Clinical Trials on Gastroesophageal Disease

Total 376955 results

Hanmi Pharmaceutical Company Limited

Completed

Safety to Evaluate the Efficacy and Safety of HIP1601 in Patients With Non Erosive Reflux Disease

Non-erosive Gastroesphageal Reflux Disease

Korea, Republic of
Yonsei University

Completed

Treatment Response of Maintenance Dose of Proton Pump Inhibitor in Patients With Nonerosive Gatroesophageal Reflux Disease

Non-erosive Gatroesophageal Reflux Disease

Korea, Republic of
Novartis

Completed

A Study to Assess the Efficacy, Safety and Tolerability of Tegaserod Alone and in Combination With Omeprazole Given Orally in Patients With Symptoms of Symptomatic Gastroesophageal Reflux Disease (sGERD)

Symptomatic Gastroespohageal Reflux Disease

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Pembrolizumab and Chemoradiotherapy for the Treatment of Unresectable Gastroesophageal Cancer

Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Unresectable Gastroesophageal Junction Adenocarcinoma | Locally Advanced Gastroesophageal Junction Adenocarcinoma | Postneoadjuvant Therapy Stage III... and other conditions

United States
GlaxoSmithKline

Completed

Open-label Comparison of 24hr Gastric pH on Days 1, 2, 7 With Once-daily Administration of Lavoltidine 40 mg.

Reflux, Gastroesophageal | Gastroesophageal Reflux Disease

Australia
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Chemoradiation and Pembrolizumab Followed by Pembrolizumab and Lenvatinib Before Surgery for the Treatment of Non-metastatic Esophageal or Esophageal/Gastroesophageal Junction Cancer

Esophageal Adenocarcinoma | Esophageal Squamous Cell Carcinoma | Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage II Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage IVA Gastroesophageal Junction Adenocarcinoma AJCC v8 | Pathologic Stage... and other conditions

United States
GlaxoSmithKline

Completed

A Study To Investigate The Effectiveness Of AH234844 (Lavoltidine) Compared With NEXIUM And Ranitidine.

Reflux, Gastroesophageal | Gastroesophageal Reflux Disease

Australia
Massachusetts General Hospital
National Cancer Institute (NCI)

Active, not recruiting

A Pilot Study of FOLFIRINOX in Combination With Neoadjuvant Radiation for Gastric and GE Junction Cancers

GastroEsophageal Cancer

United States
Roswell Park Cancer Institute
Pfizer

Recruiting

Trifluridine/Tipiracil and Talazoparib for the Treatment of Patients With Locally Advanced or Metastatic Colorectal or Gastroesophageal Cancer

Advanced Malignant Solid Neoplasm | Metastatic Colorectal Adenocarcinoma | Metastatic Gastroesophageal Junction Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Clinical Stage III... and other conditions

United States
Jesper Frank Christensen, PhD
Lundbeck Foundation; Region Capital Denmark; Beckett Foundation

Active, not recruiting

PREoperativ Study of Exercise Training (PRESET-RCT)

GastroEsophageal Cancer

Denmark
H. Lee Moffitt Cancer Center and Research Institute

Recruiting

Support Through Remote Observation and Nutrition Guidance (STRONG) Program for Gastroesophageal Cancer (GEC) Patients (STRONG-GEC)

GastroEsophageal Cancer

United States
Lexington Health Incorporated

Active, not recruiting

Transoral Fundoplication Prior to Sleeve Gastrectomy Versus RNY Gastric Bypass on GERD Symptoms in Bariatric Patients

Gastroesophageal Reflux Disease

United States
Sanofi

Completed

Scintigraphy Study to Compare the Antireflux Activity of the Z0063 Versus Gaviscon Double Action Tablets, in Healthy Adult Subjects

Gastroesophageal Reflux Disease

United Kingdom
Shire

Terminated

An Explorative Trial to Evaluate the Pharmacodynamic Effect of SPD557 on Reflux Parameters in Refractory GERD Patients

Gastroesophageal Reflux Disease

United Kingdom, Switzerland, Netherlands, Belgium, France, Germany
American Gastroenterological Association
EndoGastric Solutions

Terminated

Registry to Compare Two Surgical Treatments for GERD (STAR Registry)

GastroEsophageal Reflux Disease

United States
Krankenhaus Barmherzige Schwestern Linz

Completed

Prospective Trial on the Clinical Feasibility of a New Full Thickness Endoscopic Plication Device for Patients With GERD.

Gastroesophageal Reflux Disease

Austria
EndoStim Inc.

Unknown

Effect of Long-Term Electrical Stimulation on LES Pressure and Esophageal Acid Exposure in Patients With GERD

Gastroesophageal Reflux Disease

Chile, Colombia, India, Mexico, Netherlands, New Zealand, United Kingdom
AstraZeneca

Completed

The Use of International GerdQ Questionnaire (GERDq)

Gastroesophageal Reflux Disease

Russian Federation
Nycomed

Completed

Efficacy of Pantoprazole 20/40 mg Once Daily (od) in Patients Older Than 12 Years Who Have Gastrointestinal Symptoms of Reflux Disease (PARADE)

Gastroesophageal Reflux Disease

Germany
AstraZeneca

Completed

Esomeprazole in PPI Failures - IMPROVE

Gastroesophageal Reflux Disease

Sweden
Rabin Medical Center

Unknown

SThe Effects of Melatonin on GERD Symptoms

Gastroesophageal Reflux Disease

Israel
Rigshospitalet, Denmark
Danish Cancer Society

Completed

Significance of Peritoneal Washing Cytology Before and After Neoadjuvant Chemotherapy in Patients With Esophagogastric-junction Cancer

Gastroesophageal-junction Cancer

Denmark
Mansoura University

Withdrawn

The Potential Therapeutic Effect of Melatonin in Gastro-Esophageal Reflux Disease

Gastroesophageal Reflux Disease
Cliniques universitaires Saint-Luc- Université...

Unknown

Determinants of Efficacy of EsophyX Treatment in Gastro-Esophageal Reflux Disease

Gastroesophageal Reflux Disease

Belgium
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Recruiting

Ramucirumab and Trifluridine/Tipiracil or Paclitaxel for the Treatment of Patients With Previously Treated Advanced Gastric or Gastroesophageal Junction Cancer

Clinical Stage III Gastric Cancer AJCC v8 | Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage IV Gastric Cancer AJCC v8 | Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction... and other conditions

United States
Memorial Sloan Kettering Cancer Center

Terminated

A Single-Arm Pilot Study of Adjuvant Pembrolizumab Plus Trastuzumab in HER2+ Esophagogastric Tumors With Persistent Circulating Tumor DNA Following Curative Resection

Gastric Cancer | Esophageal Cancer | Esophageal Neoplasms | Gastroesophageal Junction Cancer | Gastric Tumor | Gastroesophageal Junction Adenocarcinoma | GastroEsophageal Cancer | Esophageal Tumor | Esophagogastric Tumors | Gastroesophageal Junction Tumor

United States
Takeda

Withdrawn

Phase 1 Dexlansoprazole Delayed-Release Capsules for Acid-Related Disorders in Infants Aged 1 to 11 Months

Pediatric Gastroesophageal Reflux Disease

United States, Italy, Israel, Mexico, Poland
Wake Forest University Health Sciences
Takeda

Completed

Correlation of Oropharyngeal Pepsin and Gastroesophageal (GE) Reflux (Pepsin)

Gastroesophageal Reflux Disease (GERD)

United States
AstraZeneca
i3 Innovus

Completed

Partial Response to Proton Pump Inhibitors (PPI) Treatment: The Cost to Society and the Burden to the Patient - a Study in the US (REMAIN)

Gastroesophageal Reflux Disease (GERD)

United States
NDO Surgical, Inc.

Terminated

A Study to Determine the Effectiveness of Endoscopic Full-Thickness Plication for the Treatment of GERD

Gastroesophageal Reflux Disease (GERD)

United States, Belgium, Germany
NDO Surgical, Inc.

Completed

Endoscopic Full-Thickness Plication for the Treatment of GERD: Long-Term Multicenter Results (LTFU)

Gastroesophageal Reflux Disease (GERD)

United States, Canada
M.D. Anderson Cancer Center

Recruiting

Pembrolizumab and Lenvatinib for the Treatment of Advanced, Unresectable, or Metastatic Gastroesophageal Adenocarcinoma

Clinical Stage III Gastric Cancer AJCC v8 | Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage IV Gastric Cancer AJCC v8 | Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction... and other conditions

United States
Daewoong Pharmaceutical Co. LTD.

Recruiting

Study to Evaluate the Efficacy and Safety of FEXUCLUE Tablet

Gastroesophageal Reflux Disease

Korea, Republic of
Daewoong Pharmaceutical Co. LTD.

Recruiting

Study to Evaluate the Improvement Effect on Subjective Symptom of FEXUCLUE Tab

Gastroesophageal Reflux Disease

Korea, Republic of
Yungjin Pharm. Co., Ltd.
Seoul National University Hospital

Completed

A Study to Compare the Safety, Pharmacokinetics and Pharmacodynamics of YPI 011 to Rabeprazole in Healthy Adult Subjects

Gastroesophageal Reflux Disease

Korea, Republic of
Indiana University

Enrolling by invitation

Transoral Incisionless Fundoplication Database Repository (TIF) (TIF)

Gastroesophageal Reflux Disease

United States
Sanofi

Completed

PH Metry Study to Compare the Antacid Activity of Z0063 Versus Gaviscon Double Action Tablets, in Healthy Adult Subjects

Gastroesophageal Reflux Disease

France
Addpharma Inc.

Completed

A Study to Compare PK, PD and Safety of the AD-214-02 and Rabeprazole

Gastroesophageal Reflux Disease

Korea, Republic of
Mansoura University Children Hospital

Completed

Role of Pepsin Assay in Wheezy Infants

Gastroesophageal Reflux Disease
Otsuka Pharmaceutical Co., Ltd.

Completed

A Trial of C13-CAC Breath Test in PPI Resistant GERD Patients

Gastroesophageal Reflux Disease

Japan
Nantes University Hospital

Completed

Stretta In Reflux Uncontrolled by IPP (SIRUP)

Gastroesophageal Reflux Disease

France
Emory University
Children's Healthcare of Atlanta

Completed

Cardiaplication: A Novel Antireflux Operation

Gastroesophageal Reflux Disease
Kaohsiung Medical University Chung-Ho Memorial...

Completed

Comparing Clinical Efficacy of One-Week Dual Delayed-Release Dexlansoprazole and Esomeprazole for GERD Grade A and B

Gastroesophageal Reflux Disease
Vanderbilt University Medical Center

Completed

Feasibility of Placing Bravo PH Capsule in Proximal Esophagus (bravo)

Gastroesophageal Reflux Disease

United States
Inje University

Withdrawn

Double-dose Rabeprazole Accelerates and Sustains the Control of Symptoms in Patients With NERD (DRNERD)

Gastroesophageal Reflux Disease

Korea, Republic of
Oxford University Hospitals NHS Trust

Completed

Comparison of Laparoscopic Nissen Versus Thal Fundoplication in Children

Gastroesophageal Reflux Disease

United Kingdom
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

IRX-2, Cyclophosphamide, and Pembrolizumab in Treating Participants With Recurrent or Metastatic Gastric or Gastroesophageal Junction Cancer

Clinical Stage IV Gastric Cancer AJCC v8 | Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction Adenocarcinoma | Postneoadjuvant Therapy Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Postneoadjuvant... and other conditions

United States
Jiangsu Alphamab Biopharmaceuticals Co., Ltd

Completed

KN026 in Patients With HER2 Expressing Gastric/Gastroesophageal Junction Cancer

Gastric/Gastroesophageal Junction Cancer

China
Daewoong Pharmaceutical Co. LTD.

Recruiting

A Study to Evaluate the Improvement Effect on Subjective Symptom of FEXUCLUE Tab

Gastroesophageal Reflux Disease

Korea, Republic of
Pfizer

Terminated

PREA, PK And Safety PASS Study Of IV Pantoprazole In Pediatric Subjects

Gastroesophageal Reflux Disease

United States, Bosnia and Herzegovina, Slovakia, Italy, Germany, Argentina, Georgia, Serbia, Ukraine

Clinical Trials on Gastroesophageal Disease

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