Clinical Trials on Genes, BRCA1
Total 772 results
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Aristotle University Of ThessalonikiCompletedPoor Ovarian Response | Androgen Receptor Gene Overexpression | Normal Responders | Bologna Criteria
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingRecurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Uterine Corpus Carcinoma | Endometrial Adenocarcinoma | Recurrent Breast Carcinoma | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast... and other conditionsUnited States
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Shanghai Chest HospitalJiangsu Hansoh Pharmaceutical Co., Ltd.Not yet recruitingLung Cancer | EGFR Gene Mutation
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Assistance Publique Hopitaux De MarseilleCompletedPatient With Breast CancerFrance
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CHANGHEE LEEPurdue University; LG Electronics Inc.CompletedBCL2 Gene mRNA OverexpressionKorea, Republic of
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Sheffield Hallam UniversityUnknownModulation of Cognitive Flexibility by Transcranial Direct Current Stimulation, Tyrosine Administration and Polymorphisms in the COMT GeneUnited Kingdom
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Guangxi Medical UniversityCompletedFull Gene Sequences of c-KIT、PDGFRA and DOG1 Are Analyzed With the Screening-sequencing Approach | Investigate the Characteristics and Variations Associated With the Different Gene Mutations of c-KIT、PDGFRA and DOG1 in GIST Patients
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Hospital Universitario La FeUnknownMalignant Hyperthermia | Polymorphisms in Genes RYR1 and CACNAS1SSpain
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xCuresCancer CommonsAvailableExpanded Access to Ulixertinib (BVD-523) in Patients With Advanced MAPK Pathway-Altered MalignanciesMelanoma | Head and Neck Cancer | Glioblastoma | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Small Bowel Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Cholangiocarcinoma | Bladder Cancer | Thyroid Cancer | ERK Mutation | MAPK Gene Mutation | KRAS Activating... and other conditionsUnited States
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Centre Hospitalier Universitaire de la RéunionNot yet recruitingBreast Cancer | BRCA2 Mutation | Genetic Disease
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Thomas Jefferson UniversityCompletedStage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Lung Non-Small Cell Carcinoma | Stage IV Lung Cancer AJCC v8 | Health Care Provider | Activating ALK Gene Mutation Negative | Activating EGFR Gene Mutation Negative | Activating ROS1 Gene Mutation NegativeUnited States
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Second Affiliated Hospital, School of Medicine,...RecruitingRisk Factors | Gene Polymorphism | Severe PeriodontitisChina
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Uludag UniversityUnknownOvarian Reserve, Endometrioma, PTEN-AKT-FOXO3 Gene ExpressionTurkey
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Korea University Guro HospitalKorean Cancer Study GroupActive, not recruitingMetastatic Cancer | HER2 Gene MutationKorea, Republic of
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Jiangsu HengRui Medicine Co., Ltd.RecruitingTreatment in HER2-negative Metastatic Breast Cancer Patients With Germline BRCA MutationChina
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German Breast GroupAstraZenecaCompletedBreast Cancer | Triple Negative Breast Neoplasms | HRpos Breast Neoplasms | BRCA 1 /2 and / or HRDGermany
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NRG OncologyNational Cancer Institute (NCI)Active, not recruitingGlioma | Oligoastrocytoma | Anaplastic Astrocytoma | Oligodendroglioma | Diffuse Astrocytoma | WHO Grade III Glioma | IDH2 Gene Mutation | IDH1 Gene Mutation | 1p/19q Co-deletionUnited States
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Taiho Oncology, Inc.Approved for marketingAdvanced CholangiocarcinomaUnited States
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National Cancer Center, JapanEisai Co., Ltd.Active, not recruitingAdvanced or Recurrent Solid Tumors | FGFR Gene AlterationsJapan
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SensorionRecruitingSensorineural Hearing Loss, Bilateral | Congenital Deafness | AUNB1 | DFNB1A | DFNB9 | OTOF Gene Mutation | GJB2 Gene MutationFrance
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Jonsson Comprehensive Cancer CenterAstraZenecaActive, not recruitingGlioblastoma | Recurrent Glioblastoma | EGFR Gene Mutation | Supratentorial Glioblastoma | EGFR Gene Amplification | TP53 wt AlleleUnited States
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Blokhin's Russian Cancer Research CenterRecruitingColorectal Cancer Metastatic | Brain Metastases, Adult | HER2 Gene Mutation | MSI | BRAF Gene Mutation | Ras (KRAS or NRAS) Gene MutationRussian Federation
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Nantes University HospitalTerminated
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Taiho Oncology, Inc.TerminatedAdvanced or Metastatic Solid Tumors Irrespective of Gene Alterations | Advanced or Metastatic Solid Tumors With Germline PTEN Inactivating MutationsUnited States, United Kingdom, Austria, France
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National Institutes of Health Clinical Center (CC)WithdrawnAcute Pain | Nitric Oxide | Gene Expression
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University of HelsinkiCompletedAndroid Obesity, Metabolic Parameters and Adipose Tissue (AT) Gene ExpressionFinland
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Day One Biopharmaceuticals, Inc.RecruitingMelanoma | Colorectal Cancer | Solid Tumor | Non Small Cell Lung Cancer | Bladder Cancer | Thyroid Cancer, Papillary | Pilocytic Astrocytoma | Bladder Urothelial Carcinoma | Non-Small Cell Adenocarcinoma | MEK Mutation | RAS Mutation | Pancreatic Acinar Carcinoma | RAF Mutation | CRAF Gene Amplification | RAF1 Gene Amplification and other conditionsUnited States, Canada, Korea, Republic of, Spain, Australia, Belgium, France
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Genzyme, a Sanofi CompanyCompletedEye Diseases | Macular Degeneration | Retinal Degeneration | Gene Therapy | Age-Related Maculopathies | Age-Related Maculopathy | Retinal Neovascularization | Maculopathies, Age-Related | Maculopathy, Age-Related | Therapy, GeneUnited States
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Northwestern UniversityNational Cancer Institute (NCI)RecruitingSarcoma | Cervical Cancer | Ovarian Cancer | Fallopian Tube Cancer | Vulvar Cancer | Endometrial Cancer | Vaginal Cancer | Hereditary Breast/Ovarian Cancer (brca1, brca2) | Uterine LeiomyomataUnited States
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Novosibirsk Scientific Research Institute for Circulatory...Recruitingto Evaluate the Association of GUCY1A3 rs7692387 Gene Polymorphism Carrier on the Development of Cardiovascular Events After Coronary Artery Bypass GraftingRussian Federation
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Cancer Institute and Hospital, Chinese Academy...RecruitingCarcinoma, Transitional Cell | HER-2 Gene AmplificationChina
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University Health Network, TorontoAbbVie; CelgeneTerminatedAcute Myeloid Leukemia | Relapsed Cancer | Refractory Cancer | IDH2 Gene MutationCanada
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Deciphera Pharmaceuticals LLCRecruitingMelanoma | Non-Small Cell Lung Cancer | Advanced Solid Tumor | Pancreatic Ductal Adenocarcinoma | BRAF Gene Mutation | RAS Mutation | NF1 Mutation | RAF Mutation | CRAF Gene MutationUnited States
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Taiho Oncology, Inc.TerminatedNon-Small Cell Lung Cancer | KRAS Gene Mutation | Advanced or Metastatic Solid Tumors Irrespective of Gene AlterationsUnited States
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Spark TherapeuticsCompletedHematologic Diseases | Blood Coagulation Disorders, Inherited | Coagulation Protein Disorders | Hemorrhagic Disorders | Genetic Diseases, Inborn | Genetic Diseases, X-Linked | Gene Therapy | Blood Coagulation Disorder | Gene Transfer | Adeno-Associated Virus (AAV) | Factor VIII (FVIII) | Factor VIII (FVIII)... and other conditionsUnited States
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University of VirginiaNot yet recruitingGenetic Predisposition | Gene Mutation-Related Cancer
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Fondazione Policlinico Universitario Agostino Gemelli...RecruitingGenetic Predisposition to Disease | Gene Rearrangement | Genome InstabilityItaly
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Institut CurieRecruitingGenetic Predisposition | Gene Mutation-Related CancerFrance, Guadeloupe, Martinique, Réunion
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University Hospital, BrestUnknownBreast Neoplasms | HER-2 Gene AmplificationFrance
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Taiho Oncology, Inc.RecruitingAdvanced Cholangiocarcinoma | FGFR2 Fusions | Gene RearrangementUnited States, Korea, Republic of, Spain, Japan, Portugal, Italy, China, Argentina, Brazil, Poland, Australia
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Peking Union Medical CollegeUnknownBreast Cancer | HER2 Gene MutationChina
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Tel-Aviv Sourasky Medical CenterUnited States Department of DefenseRecruitingEvaluation of the Frequency and Severity of Sleep Abnormalities in Patients With Parkinson's DiseaseParkinson Disease | GBA Gene Mutation | Leucine-rich Repeat Kinase 2 (LRRK2) Gene MutationIsrael
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National Cancer Institute (NCI)CompletedRecurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Breast Carcinoma | Ovarian Carcinoma | Pancreatic Carcinoma | Prostate Carcinoma | Recurrent Breast Carcinoma | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative... and other conditionsUnited States
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Cynvenio BiosystemsUnknownTriple Negative Breast Cancer | BRCA Mutation | Natural Killer CellsUnited States
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Centre Hospitalier Universitaire de Saint EtienneCompleted
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BayerRecruitingAdvanced or Recurrent Solid Tumor Harboring an NTRK Gene FusionJapan
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HutchmedRecruitingIsocitrate Dehydrogenase Gene MutationSpain, United States
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Institut Claudius RegaudRecruitingDDX41 Gene MutationFrance
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Associazione Italiana per lo Studio del PancreasRecruitingLynch Syndrome | BRCA1 Mutation | BRCA2 Mutation | Familial Pancreatic Cancer | Hereditary Pancreatitis | Peutz-Jeghers Syndrome | FAMMM - Familial Atypical Mole Malignant Melanoma SyndromeItaly
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Intergroupe Francophone de Cancerologie ThoraciquePfizerCompletedALK Gene Rearrangement Positive | Non-small Cell Lung Cancer Metastatic | ROS-1 Gene Rearrangement PositiveFrance