Clinical Trials on Graft Failure in United Kingdom

Total 4967 results

MolecuLight Inc.

Unknown

Presence of Fluorescence Signature to Predict Graft Failure Using MolecuLight i:X

Skin Graft (Allograft)(Autograft) Failure

United Kingdom
Swedish Orphan Biovitrum
PRA Health Sciences; BioMérieux; Cytel Inc.

Terminated

A Clinical Study to Investigate Interferon Gamma (IFNɣ) Signature in Patients Post HSCT and in Patients With Impaired HSC Proliferation Pre-transplant

Graft Failure

Italy, Belgium, United Kingdom, France, Germany, Netherlands
Masonic Cancer Center, University of Minnesota

Recruiting

Treatment of Graft Failure After Hematopoietic Stem Cell Transplantation

Primary Graft Failure | Secondary Graft Failure

United States
Baylor College of Medicine
The Methodist Hospital Research Institute

Terminated

Stem Cell Transplantation for Patients With Graft Failure Following an Allogeneic Transplant, Using Identical or Near Identical Donors and Less Toxic Conditioning With CAMPATH 1H

Graft Failure

United States
Colorado Blood Cancer Institute

Unknown

Fludarabine and 400 CGY Total Body Irradiation for Recipients of HLA-Matched or Mis-Matched Family or Unrelated Donor Hematopoietic Stem Cell Transplants Who Have Rejected Their First Allogeneic Stem Cell Transplant

Graft Failure

United States
University of Edinburgh
Kidney Cancer UK

Terminated

Heme Arginate in Transplantation Study (HOT2)

Renal Transplant Rejection | Renal Transplant Failure

United Kingdom
Imperial College Healthcare NHS Trust

Completed

Standard Versus Prolonged-release Tacrolimus Monotherapy After Alemtuzumab Induction in Kidney Transplantation (TAESR)

Graft Rejection | End-stage Renal Failure

United Kingdom
University of Oklahoma
University of Michigan; Emory University

Recruiting

REVEAL Biomarkers of Engraftment After Alternative Donor HSCT (REVEAL)

Primary Graft Failure

United States
Emory University

Terminated

Terminal Graft Failure

Graft Failure | Orthotopic Heart Transplantation

United States
Mitchell Horwitz, MD
Genzyme, a Sanofi Company

Completed

Donor Enhancement With Plerixafor Post Myeloablative Allogeneic Transplant

Failure of Bone Marrow Graft

United States
University of Edinburgh
NHS Lothian

Completed

Induction of HO-1; a Therapeutic Approach to Reduce Ischaemia Reperfusion Injury (IRI) Following Deceased Donor Renal Transplantation (HOT)

Ischemia-reperfusion Injury | Graft Failure

United Kingdom
Baylor Research Institute

Active, not recruiting

Phase II Study Evaluating the Efficacy of Tacrolimus Extended Release Tablets to Twice Daily Tacrolimus Dosing Regimen (Veloxis)

Compliance, Patient | Graft Failure | Heart Transplant Rejection

United States
Mayo Clinic

Withdrawn

Analysis of Biomarkers for Acute Graft-versus-Host Disease (GVHD)

Blood Stem Cell Transplant Failure

United States
University of Regensburg
European Commission

Completed

Reference Group Trial for The ONE Study

End-stage Renal Failure | Kidney Graft Rejection

United States, Italy, Germany, France, United Kingdom
University of Kansas Medical Center

Completed

Pilot Study: Patients With Chronic Active Graft Versus Host Disease That Have Failed or Not Tolerated Standard Therapy.

Graft Versus Host Disease | Blood Stem Cell Transplant Failure

United States
Loma Linda University

Recruiting

Dd-cfDNA and Treg in Prediction of Kidney Transplant Acute Rejection

Graft Failure | Acute Rejection of Renal Transplant

United States
M.D. Anderson Cancer Center

Completed

Robotic Harvest of the Latissimus Dorsi (LD) Muscles

Cancer | Complications | Surgical Procedure, Unspecified | Other Reconstructive Surgery | Failure of Muscle Graft

United States
Speedel Pharma Ltd.
Quintiles, Inc.

Completed

A Clinical Study to Assess the Safety of PEG-Hirudin (SPP200) Compared to Heparin in Patients Who Are on Haemodialysis

Chronic Kidney Failure | Vascular Graft Occlusion

United States
Joseph Antin
Miltenyi Biomedicine GmbH

No longer available

CliniMACS® CD34+ Reagent System for Expanded Access Use

Graft Failure | Delayed Graft Function | Graft-Versus-Host Disease(GVHD) | Anemia Due to Disturbance of Proliferation and/or Differentiation of Hematopoietic Stem Cells

United States
University College, London
Medical Research Council

Recruiting

Transfer of Effector Memory T Cells (Tem) Following Allogeneic Stem Cell Transplantation (ToTem)

Lymphoma | Myelodysplastic Syndromes | Leukemia | Myeloma | Graft Vs Host Disease | Severe Aplastic Anemia | Primary Immune Deficiency

United Kingdom
Cynata Therapeutics Limited

Completed

A Study of CYP-001 for the Treatment of Steroid-Resistant Acute Graft Versus Host Disease

Graft vs Host Disease

Australia, United Kingdom
University Hospitals, Leicester

Terminated

Transcutaneous Electrical Nerve Stimulation for Local Anaesthesia (TENS-LA)

Skin Graft | Donor Site Complication

United Kingdom
University Hospital Birmingham

Unknown

T-Lymphocyte Infusion or Standard Therapy in Treating Patients at Risk of Cytomegalovirus Infection After a Donor Stem Cell Transplant

Graft Versus Host Disease | Nonneoplastic Condition

United Kingdom
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Terminated

Prospective Outcomes of Second-Line Therapy in Acute Graft-Versus-Host Study Including ECP (POSTAGE) (POSTAGE)

Graft Versus Host Disease

United States, United Kingdom, Austria, Germany
Sheffield Teaching Hospitals NHS Foundation Trust
3M

Completed

Prevena Incision Management (Prevena)

Cardiac Event | Complication of Coronary Artery Bypass Graft | Coronary Bypass Graft Stenosis | Arrest; Cardiac, Complicating Surgery

United Kingdom
The Royal Wolverhampton Hospitals NHS Trust
Maquet Cardiovascular

Completed

MACCE After Endoscopic Vein Harvest for CABG (MAQEH)

Complications Due to Coronary Artery Bypass Graft

United Kingdom
Vital Therapies, Inc.

Terminated

Safety and Efficacy of the ELAD System (ELAD) to Treat Acute Liver Failure (ALF)

Acute Liver Failure | Fulminant Hepatic Failure | Primary Graft Non-Function | Surgically-Induced Liver Failure

United States
Edixomed Ltd

Terminated

Nitric Oxide Generating Gel Dressing in Patients With Superficial Partial Thickness Wounds (ProNOx2)

Superficial Partial Thickness Burn | Skin Graft; Complications

United Kingdom
Minneapolis Heart Institute Foundation

Recruiting

Native Coronary Artery Instead of SAphenous Vein Graft Intervention for Treatment of Significant Saphenous Vein Graft Lesions

Percutaneous Coronary Intervention | Target Vessel Failure in Saphenous Vein Grafts

United States
University of California, Davis

Recruiting

Tumescence in HNC Skin Graft Reconstruction

Head and Neck Cancer | Surgery--Complications | Graft Failure

United States
Guy's and St Thomas' NHS Foundation Trust
King's College London

Recruiting

Siderophores for Imaging Infection Using 68Ga-DFO (GaDFO)

Vascular Graft Infection

United Kingdom
Mallinckrodt

Completed

Safety and Efficacy Study of Photopheresis With UVADEX to Prevent Graft-versus-Host Disease

Graft-versus-Host Disease

United States, Australia, United Kingdom, Slovakia, Brazil, Germany, Italy, Portugal, Turkey
Cambridge University Hospitals NHS Foundation Trust
University of Cambridge; Cambridge Stem Cell Institute, Cambridge; Anne McLarent... and other collaborators

Unknown

Regenerative Cellular Therapies, Physiology, Pathology and Developmental Biology (RCT)

Diabetes Mellitus | Graft Rejection | Transplantation

United Kingdom
Mallinckrodt

Completed

Safety and Efficacy Study of Photopheresis Plus Standard Therapy to Treat Chronic Graft-versus-Host Disease

Graft-versus-Host Disease

United States, Australia, France, Italy, Austria, Germany, Portugal, Slovakia, Spain, Switzerland, Turkey, United Kingdom
Reza Dana, MD

Completed

Safety and Efficacy of Bevacizumab in High-Risk Corneal Transplant Survival

Corneal Neovascularization | Corneal Graft Failure

United States
Mallinckrodt
PRA Health Sciences

Terminated

Extracorporeal Photoimmune Therapy With UVADEX for the Treatment of Acute Graft Versus-Host Disease

Acute Graft-versus-Host Disease

United States, Canada, Germany, United Kingdom, Australia, Austria, Belgium, Italy, France, Netherlands, Switzerland
Northwestern Memorial Hospital

Unknown

Study of Allogeneic Bone Marrow and T-Cell Depleted, CD34+ Peripheral Blood Stem Cell Transplantation in Patients With Aplastic Anemia

Aplastic Anemia | Graft Versus Host Disease

United States
Incyte Corporation

Terminated

Safety and Efficacy of Itacitinib in Combination With Corticosteroids for Treatment of Graft-Versus-Host Disease in Pediatric Subjects

Acute Graft-versus-host Disease

United States, Spain, France, Italy, United Kingdom, Germany
Reza Dana, MD
United States Department of Defense; New York Presbyterian Hospital; Bascom Palmer...

Completed

A Multi-Center Study of the Safety and Efficacy of Bevacizumab in High-Risk Corneal Transplant Survival

Corneal Neovascularization | Corneal Graft Failure

United States
Imperial College London

Unknown

Renal Artery Denervation in Chronic Heart Failure Study (REACH)

Chronic Systolic Heart Failure

United Kingdom
Yale University
Johns Hopkins University; National Institute of Diabetes and Digestive and...

Completed

Deceased Donor Biomarkers and Recipient Outcomes (DDS)

End Stage Renal Disease | Acute Kidney Injury | Graft Failure | Delayed Graft Function | Deceased Donor Kidney Transplant

United States
Gilead Sciences

Terminated

Efficacy and Tolerability of Entospletinib in Combination With Systemic Corticosteroids as First-Line Therapy in Adults With Chronic Graft Versus Host Disease (cGVHD)

Chronic Graft Versus Host Disease

Spain, Korea, Republic of, United States, Germany, Canada, France, United Kingdom
Mallinckrodt
Parexel

Completed

Extracorporeal Photopheresis (ECP) With Methoxsalen for Chronic Graft Versus Host Disease (cGVHD)

Chronic Graft Versus Host Disease

United States, France, Germany, United Kingdom, Spain, Italy, Austria, Hungary
Jazz Pharmaceuticals

Completed

An Open-Label Study of Defibrotide for the Prevention of Acute Graft-versus-Host-Disease (AGvHD)

Acute-graft-versus-host Disease | Graft-versus-host Disease

United States, Belgium, United Kingdom, Greece, Germany, Spain, France, Italy, Austria, Canada, Bulgaria, Croatia, Poland, Portugal
Stanford University
Novartis

Completed

Phase 1 Nilotinib in Steroid Dependent/Refractory Chronic Graft Versus Host Disease

Lymphoma, Non-Hodgkin | Lymphoma, T-Cell, Peripheral | Bone Marrow Transplant Failure

United States, Canada
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Of The Safety And Efficacy Of Conversion From A CNI To Sirolimus In Renally-Impaired Heart Transplant Recipients

Graft Rejection | Kidney Failure

United States, Spain, Canada, Switzerland, Austria, Australia, New Zealand
University College London Hospitals
Medical Research Council

Unknown

Predictive Utility of DASIMAR as a Prognostic Biomarker in Acute-on-chronic Liver Failure (ACLF) (DASIMAR)

Liver Cirrhosis

United Kingdom
University of Aberdeen

Completed

Perhexiline Therapy in Heart Failure With Preserved Ejection Fraction Syndrome

Diastolic Heart Failure

United Kingdom
Bristol-Myers Squibb

Completed

An Investigational Study of Continuous 8-Hour Intravenous Administrations of BMS-986231 in Participants With Heart Failure and Reduced Heart Function Given a Standard Dose of Loop Diuretic

Congestive Heart Failure | Heart Decompensation | Cardiac Failure | Myocardial Failure

United Kingdom
National Cancer Institute (NCI)

Terminated

Biomarkers in Acute Graft-Versus-Host Disease and Extracorporeal Photopheresis Added to Investigator Chosen Therapies of Steroid Refractory Acute GVHD

Graft vs Host Disease | Graft-Versus-Host Disease | Chronic Graft vs. Host Disease

United States

Clinical Trials on Graft Failure in United Kingdom

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