Clinical Trials on Healthy Obesity, Metabolically in South Africa

Total 531 results

Columbia University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Obesogenic Origins of Maternal and Child Metabolic Health Involving Dolutegravir (ORCHID)

Obesity | HIV | Maternal Obesity During Childbirth | Maternal Obesity Complicating Pregnancy | Obesity, Infant

South Africa
Crossject

Completed

Bioavailability Study of Midazolam Administered as a Solution by Conventional Syringe or ZENEO®

Healthy

South Africa
Actavis Inc.

Withdrawn

Pivotal Bioequivalence Study of Exemestane 25 mg Tablets Under Fasting Conditions in Healthy Subjects

Healthy

South Africa
NeuroVive Pharmaceutical AB

Completed

A Study to Compare the Bioavailability and Pharmacokinetics of Cyclosporine After Intravenous Administration of NEUROSTAT®, a CREMOPHOR® EL-free Lipid Emulsion, and SANDIMMUNE® Injection (a Suspension of Cyclosporine in CREMOPHOR® EL) in Healthy Volunteers

Healthy

South Africa
Immtech Pharmaceuticals, Inc

Terminated

Randomized, Double-Blind Phase 1 Safety and Tolerability Study of Pafuramidine Maleate (DB289) in Healthy Subjects

Healthy

South Africa
Boehringer Ingelheim

Completed

Comparison of the Bioavailability of Diclofenac in a Combination Product (Diclofenac 2% + Capsaicin 0.075% Topical Gel) With Two Diclofenac Only Products, Diclofenac Mono Gel 2% and Voltarol® 12 Hour Emulgel 2.32% Gel, in Healthy Volunteers

Healthy

South Africa
Boehringer Ingelheim

Completed

Bioequivalence of a Fixed Dose Combination Tablet Containing 400 mg Ibuprofen and 60 mg Pseudoephedrine-HCl Compared to Two Film Coated Fixed Dose Combination Tablets RhinAdvil(R)(200 mg Ibuprofen and 30 mg Pseudoephedrine-HCl) Administered in Healthy Subjects

Healthy Volunteers

South Africa
North-West University, South Africa
Medical Research Council, South Africa; National Research Foundation of South...

Active, not recruiting

Exercise, Arterial Modulation and Nutrition in Youth South Africa Study (ExAMIN-Youth)

Hypertension | Childhood Obesity | Retinal Artery Stenosis

South Africa
Boehringer Ingelheim

Completed

To Determine Blood Concentrations of Ibuprofen and Caffeine in a Tablet Against Ibuprofen Alone From Another Tablet

Healthy

South Africa
London School of Economics and Political Science
University of Witwatersrand, South Africa

Recruiting

Improved Access to Quality Care and Healthcare Use

Health, Subjective | Health Knowledge, Attitudes, Practice | Health Care Utilization

South Africa
Swiss Federal Institute of Technology
North-West University, South Africa

Completed

Omega-3 Fatty Acid Supplementation and Fractional Iron Absorption in Obese South African Women

Obesity

South Africa
PATH
The Emmes Company, LLC

Completed

Safety and Immunogenicity Study of Trivalent P2-VP8 Subunit Rotavirus Vaccine in Adults, Toddlers and Infants

Healthy

South Africa
Mitsubishi Tanabe Pharma Corporation

Completed

Safety and Immunogenicity of MT-5625 in Healthy Adults, Toddlers and Infants

Healthy

Australia, South Africa
University of Cape Town

Completed

Impact of Employee Wellness Programme

Obesity

South Africa
Nestlé

Terminated

Effect of a Starter Formula With Synbiotics on Stool Microbiota in Infants After Normal or Caesarean Section Delivery

Healthy Full Term Infants

South Africa
University of Cape Town

Unknown

Pregnancy-Related Obesity Prevention Through Education & Communication Technology in AFRICA:The PROTECT-AFRICA STUDY (PROTECT-AFRI)

Obesity

South Africa
Novo Nordisk A/S

Completed

Comparison of Two Insulin Aspart Formulations in Healthy Volunteers

Healthy | Diabetes

South Africa
Novo Nordisk A/S

Completed

Bioequivalence of Two Formulations of Biphasic Insulin Aspart 50 in Healthy Male Subjects

Healthy | Diabetes

South Africa
Novo Nordisk A/S

Completed

Bioequivalence of Two Formulations of Biphasic Insulin Aspart 70 in Healthy Male Subjects

Healthy | Diabetes

South Africa
University of Witwatersrand, South Africa
UNITAID

Completed

CHARACTERISE - A Cross-sectional, Observational Study to Characterise the Transition to Dolutegravir-based Regimens in South Africa in Terms of the Emergence of Obesity, Viral Re-suppression and Integration Into Routine Programme Care (CHARACTERISE)

Dolutegravir

South Africa
University of KwaZulu
The ELMA Foundation; KwaZulu Natal Department of Health

Completed

An Evaluation of the Effectiveness of e-IMCI Implementation in Primary Health Care Clinics in South Africa.

Primary Health Care | Child Health | Clinical Practice Guidelines

South Africa
University of Witwatersrand, South Africa
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Completed

Effectiveness of a Pre-adolescent Inter-generational Intervention to Address HIV and Obesity

Obesity | Hiv

South Africa
University of Witwatersrand, South Africa
University of Stellenbosch; University of Cape Town; University of KwaZulu; University...

Completed

Group B Strep Correlates of Protection Study (GBSCoP)

Maternal Health, Child Health, Infectious Diseases

South Africa
University of Cape Town
University of Oxford; Orion Corporation, Orion Pharma

Completed

Single-dose Novel Selective alpha2c Antagonist Pharmaco-MRI Study in Healthy Volunteers (SNAP_MRI)

Healthy Volunteer

South Africa
University of Maryland, College Park
National Institute on Drug Abuse (NIDA); Medical Research Council, South Africa

Active, not recruiting

Siyakhana Peer: Evaluating a Peer Recovery Coach Model to Reduce Substance Use Stigma in South African HIV Care

Substance-Related Disorders | HIV | Substance Use | Substance Use Disorders | Treatment Adherence | Treatment Adherence and Compliance | Stigmatization | Delivery of Health Care | Stigma, Social | Attitude of Health Personnel | Community Health Workers | Health Personnel | Health Personnel Attitude | Health Care Seeking... and other conditions

South Africa
University of Cape Town

Completed

The Impact of Obesity on Cardiac Function in Pregnancy (CFOP)

Obesity | Pregnancy

South Africa
Statens Serum Institut
Bill and Melinda Gates Foundation; Aurum Institute; Leiden University Medical... and other collaborators

Recruiting

First-in-Human Trial of the Novel Tuberculosis Vaccine Candidate, H107e/CAF®10b (nTB-01)

Healthy

South Africa
University of KwaZulu
University of California, San Francisco; Centers for Disease Control and Prevention and other collaborators

Completed

Effectiveness of an HIV-adapted IMCI Training and Supervision Programme for Community Health Workers

Infant Feeding Practices | Prevention of Mother-to-child Transmission of HIV | Antenatal Health Care Utilization | Postnatal Health Care Utilization

South Africa
University of Cape Town
National Research Foundation of South Africa

Completed

Randomised Trial of Two Educational Intervention for Improving Evidence-based Practice Knowledge, Atttitudes and Practice (OTEBP)

Health Knowledge, Attitudes, Practice

South Africa
University of Maryland, College Park
National Institute of Mental Health (NIMH); Medical Research Council, South...

Completed

Community Health Worker Training to Reduce Depression and Substance Use Stigma in TB/HIV Care in South Africa (Siyakhana)

Substance-Related Disorders | Depression | Tuberculosis | Hiv | Mental Health Disorder | Mental Disorder | Health Care Utilization | Treatment Adherence and Compliance | Social Stigma | Attitude of Health Personnel | Community Health Workers | Health Care Delivery

South Africa
University of Cape Town

Completed

Health System Dynamic & Resource Requirement in a South African COVID-19 Field Hospital

COVID-19 Pandemic | Low-Income Population | Global Health | Health Resources | Field Hospitals | Health Systems

South Africa
University of South Carolina
Johns Hopkins University; Eunice Kennedy Shriver National Institute of Child...

Active, not recruiting

Promoting Nutrition and Physical Activity in Family Child Care (FCCH)

Physical Activity | Obesity, Childhood | Diet, Healthy

United States
City University of Hong Kong
Stanford University; Harvard University

Completed

International REACH Forgiveness Intervention

Mental Health Wellness

Colombia, Indonesia, South Africa, Ukraine
Innovations for Poverty Action
Bill and Melinda Gates Foundation; U.S. National Science Foundation; Broadening... and other collaborators

Completed

Evaluation of Impacts of Access to Credit and Loan Size for Microcredit Clients in South Africa

Depression | Stress | Mental Health

South Africa
IGM Biosciences, Inc.

Terminated

Evaluation of IGM-6268 in Healthy Adults and Patients With Mild to Moderate COVID-19

COVID-19 | Healthy Volunteers

South Africa
North-West University, South Africa
GlaxoSmithKline; Novartis; Pfizer; Boehringer Ingelheim; Medical Research Council; Medical... and other collaborators

Active, not recruiting

The African-PREDICT Study (PREDICT)

Cardiovascular Diseases | Hypertension | Health Risk Behaviors | Arterial Stiffness | Young | Renin Hypertension

South Africa
University of Pennsylvania

Withdrawn

Vitality Health Incentives for Physical Activity

Obesity

United States, South Africa
Alvotech Swiss AG

Completed

AVT03 With Prolia in Healthy Male Subjects

Healthy Male Subjects

Australia, New Zealand, South Africa
Amsterdam UMC, location VUmc
Syddansk Universitet, Denmark; Stichting Alexander (the Netherlands); Aalborg... and other collaborators

Enrolling by invitation

YoPA - A Youth-centred Participatory Action (YoPA)

Physical Activity | Sleep | Health Promotion

Denmark, Netherlands, Nigeria, South Africa
University of South Carolina
National Institute on Minority Health and Health Disparities (NIMHD)

Completed

"GameDay Ready": Evaluating a Behavioral Weight Management Program for Black Men Living in the Rural South

Obesity | Diet, Healthy | Physical Inactivity

United States
Eastern Virginia Medical School
Gilead Sciences; United States Agency for International Development (USAID); FHI... and other collaborators

Active, not recruiting

Project Engage: Oral PrEP Acceptability

Adherence, Medication | Acceptability of Health Care

South Africa, Zimbabwe
Alvotech Swiss AG

Completed

AVT03 With Xgeva in Healthy Male Subjects

This is a Phase I Study Conducted in Healthy Volunteers

South Africa, Poland, United Kingdom
University of South Carolina

Recruiting

Healthy Kids Beyond the Bell: Investigating the Impact of After-School and Summer Programs

Pediatric Obesity | Socioeconomic Factors | Health Status Disparities | Ethnic Group

United States
Boston University
National Institute of Mental Health (NIMH); Africa Health Research Institute

Completed

Life Plans Intervention Study

HIV/AIDS | Health Knowledge, Attitudes, Practice | Chronic HIV Infection

South Africa
University of South Carolina

Recruiting

Determining the Optimal Amount of Structured Environments for Healthy Kids (DOSE)

Pediatric Obesity | Socioeconomic Factors | Health Status Disparities | Ethnic Groups

United States
Loyola University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); University... and other collaborators

Withdrawn

Vitamin D Ancillary Study in 5 Populations of African Origin (VIDA)

Obesity | Cardiovascular Disease

South Africa, Jamaica, Ghana, United States, Seychelles
University of California, San Francisco
Johns Hopkins University; National Institute of Allergy and Infectious Diseases... and other collaborators

Recruiting

Rapid Research in Diagnostics Development for TB Network (R2D2 Kids) and Assessing Diagnostics At POC for TB in Children (ADAPT for Kids)

Tuberculosis | Diagnostics | Global Health

Mozambique, South Africa, Uganda
North-West University, South Africa
University of Zurich; University of Cape Town; Medical Research Council, South... and other collaborators

Recruiting

National Blood Pressure Screening in Children to Improve Paediatric Healthcare in South Africa

Hypertension | Obesity, Childhood | Obesity, Adolescent

South Africa, Switzerland
Desmond Tutu HIV Foundation
Karolinska Institutet; University of North Carolina, Chapel Hill; ViiV Healthcare and other collaborators

Completed

Bidirectional, Upbeat Communication and Differentiated, Distanced Care for Young People (BUDDY)

HIV Infections | Covid19 | Health Care Utilization | Gender-based Violence

South Africa
Novartis Vaccines
GlaxoSmithKline

Completed

Study to Identify Factors Influencing Access of Pregnant Women and Their Infants to Local Healthcare Systems

Pregnancy, Newborn Health

Dominican Republic, Mozambique, Panama, South Africa

Clinical Trials on Healthy Obesity, Metabolically in South Africa

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