Clinical Trials on Hemolytic-Uremic Syndrome in France

Total 3526 results

Alexion

Completed

An Open-label, Multi-center Clinical Trial of Eculizumab in Adult Patients With Atypical Hemolytic-uremic Syndrome

Atypical Hemolytic-Uremic Syndrome

United Kingdom, United States, France, Italy, Germany, Spain, Belgium
Alexion Pharmaceuticals

Completed

An Open-Label, Multi-Center Clinical Trial of Eculizumab in Pediatric Patients With Atypical Hemolytic-Uremic Syndrome (aHUS)

Atypical Hemolytic-Uremic Syndrome

United Kingdom, Belgium, United States, Germany, Italy, France, Netherlands, Australia, Canada
Nantes University Hospital

Completed

Study Assessing an Algorithm-based Strategy of Eculizumab Discontinuation in Children and Adults With aHUS (STOPECU)

Atypical Hemolytic Uremic Syndrome

France
University Hospital, Toulouse

Completed

Eculizumab in Shiga-toxin Related Hemolytic and Uremic Syndrome Pediatric Patients - ECULISHU (ECULISHU)

Hemolytic Uremic Syndrome of Childhood

France
Alexion Pharmaceuticals

Completed

Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Resistant aHUS (aHUS)

Atypical Hemolytic Uremic Syndrome

France, United States, Austria, Germany, United Kingdom
Alexion Pharmaceuticals

Completed

Open Label Controlled Trial of Eculizumab in Adult Patients With Plasma Therapy-sensitive Atypical Hemolytic Uremic Syndrome (aHUS) (aHUS)

Atypical Hemolytic Uremic Syndrome

Canada, United Kingdom, France, Germany, Sweden, Netherlands, Italy
Alexion
Syneos Health

Recruiting

Atypical Hemolytic-Uremic Syndrome (aHUS) Registry

Atypical Hemolytic-Uremic Syndrome

France, Germany, Israel, Italy, United Kingdom, Canada, United States, Australia, Belgium, Denmark, Korea, Republic of, Poland, Russian Federation, Spain, Taiwan
University Hospital, Tours
Hospices Civils de Lyon; University Hospital, Strasbourg, France; University... and other collaborators

Active, not recruiting

Personalized Spacing of Eculizumab Infusions Based on Therapeutic Pharmacological Monitoring (EspacECU) (EspacECU)

Hemolytic-Uremic Syndrome, Atypical

France
Alexion Pharmaceuticals

Completed

Open Label Controlled Trial of Eculizumab in Adult Patients With Plasma Therapy-Resistant aHUS (aHUS)

Atypical Hemolytic Uremic Syndrome

France, United States, Austria, Germany, United Kingdom
Alexion Pharmaceuticals

Terminated

aHUS Observational Long Term Follow-Up (LTFU)

Atypical Hemolytic Uremic Syndrome

France, Canada, United States, Belgium, Italy, United Kingdom, Netherlands, Australia, Austria, Germany, Sweden, Switzerland
University Hospital, Bordeaux

Completed

Outbreak of Hemolytic Uremic Syndrome Linked to Escherichia Coli of Serotype O104:H4 (SHU O104 CUB)

Escherichia Coli Infections | Hemolytic-uremic Syndrome

France
Alexion

Completed

A Retrospective, Observational, Non-interventional Trial to Assess Eculizumab Treatment Effect in Patients With Atypical Hemolytic Uremic Syndrome (aHUS)

Atypical Hemolytic Uremic Syndrome (aHUS)

United States, France, Germany, Spain, Switzerland, Netherlands, Canada, Austria
Alexion

Completed

Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Sensitive aHUS (aHUS)

Atypical Hemolytic Uremic Syndrome

Canada, United Kingdom, France, Germany, Netherlands, Sweden, Italy
Alexion Pharmaceuticals, Inc.

Completed

Study of ALXN1210 in Complement Inhibitor Treatment-Naïve Adult and Adolescent Participants With Atypical Hemolytic Uremic Syndrome (aHUS)

Atypical Hemolytic Uremic Syndrome (aHUS)

United States, France, Spain, Taiwan, United Kingdom, Australia, Belgium, Germany, Italy, Japan, Korea, Republic of, Russian Federation, Austria, Canada
Hoffmann-La Roche
Chugai Pharmaceutical

Recruiting

A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Adult and Adolescent Participants With Atypical Hemolytic Uremic Syndrome (aHUS) (COMMUTE-a)

Atypical Hemolytic Uremic Syndrome

Canada, United States, Japan, France, Spain, Mexico, Peru, Brazil, New Zealand, Belgium, China, Germany, Hungary, Israel, Italy, Poland, South Africa, Turkey, India
Assistance Publique - Hôpitaux de Paris

Recruiting

Eculizumab in Hypertensive Emergency-associated Hemolytic Uremic Syndrome (HYPERSHU)

Hypertensive Emergency-associated Hemolytic Uremic Syndrome

France
Assistance Publique - Hôpitaux de Paris

Completed

Azithromycin in Post Diarrheal Haemolytic and Uremic Syndrome (ZITHROSHU)

Haemolytic and Uremic Syndrome

France
Hoffmann-La Roche
Chugai Pharmaceutical

Recruiting

A Study Evaluating the Efficacy, Safety, Pharmacokinetics and Pharmacodynamics of Crovalimab in Pediatric Participants With Atypical Hemolytic Uremic Syndrome (aHUS) (COMMUTE-p)

Atypical Hemolytic Uremic Syndrome

United States, Belgium, China, France, Spain, Canada, South Africa, Japan, Brazil, Italy, Poland, India, Hungary, Mexico, Israel
Assistance Publique Hopitaux De Marseille

Completed

Study of 'Vascular Competence' Profile and Endothelial Activation in the Hemolytic Uremic Syndrome in Children and Adults (SHU)

Hemolytic Uremic Syndrome

France
University Hospital, Tours

Recruiting

French National Cohort MATRIX "Renal and Systemic Thrombotic Microangiopathy" (MATRIX)

Kidney Diseases | Hemolytic Uremic Syndrome | Acute Kidney Injury | Thrombotic Microangiopathy | Nephrology

France
Centre Hospitalier Universitaire Dijon

Recruiting

Role of T Follicular Helper Cells in Autoimmune Hemolytic Anemia (TFH in AIHA) (TFH and AIHA)

Autoimmune Hemolytic Anemia

France
Assistance Publique - Hôpitaux de Paris
Hoffmann-La Roche

Completed

Rituximab in Auto-Immune Hemolytic Anemia (RAHIA)

Warm Autoimmune Hemolytic Anemia

France
University Hospital, Bordeaux

Completed

Evaluating the Interest of Interleukine-2 for Patients With Active Warm Hemolytic Anemia Resistant to Conventional Treatment (ANEMIL)

Autoimmune Hemolytic Anemia

France
Centre Hospitalier Universitaire Dijon

Completed

Immunopathology of Autoimmune Hemolytic Anemia (IAHAI)

Autoimmune Hemolytic Anemia

France
Centre Hospitalier Universitaire, Amiens

Withdrawn

Evaluation of Interaction Between Immunosuppressive Drugs and Protein-bound Uremic Toxins in Renal Transplant Patients (DRUGTOX)

Immunosuppression | Kidney Transplant | Uremic; Toxemia

France
Centre Hospitalier Universitaire Dijon

Recruiting

Efficacy of Prolonged Anticoagulation for Primary Prevention of Venous Thromboembolic Disease in Autoimmune Hemolytic Anemia: a Prospective, Phase II, Randomized, Multicenter Study (API-AHAI)

Autoimmune Hemolytic Anemia | Venous Thromboembolic Disease | Prolonged Anticoagulation

France
Association ECHO
Elsan; European Clinical Trial Experts Network

Completed

Retrospective Study Evaluating the Contribution of Rheopheresis in the Treatment of Uremic Calciphylaxis (RHEO-CUA) (RHEO-CUA)

Rheopheresis | Calcifying Uremic Arteriolopathy | Uremic Calciphylaxis

France
Sanofi

Terminated

Safety, Pharmacokinetics, and Efficacy of Subcutaneous Isatuximab in Adults With Warm Autoimmune Hemolytic Anemia (wAIHA)

Warm Autoimmune Hemolytic Anemia (wAIHA)

United Kingdom, Belgium, Netherlands, France, United States, Germany, Hungary, Italy
Incyte Corporation

Completed

A Study of INCB050465 in Participants With Autoimmune Hemolytic Anemia

Autoimmune Hemolytic Anemia

United States, France, Italy, Austria
University Hospital, Toulouse

Recruiting

French Registry of Adult Patients With Immune Thrombocytopenia and Autoimmune Hemolytic Anemia (CARMEN)

Immune Thrombocytopenia | Autoimmune Hemolytic Anemia

France
Rigel Pharmaceuticals

Enrolling by invitation

A Phase 3 Open Label Extension Study of Fostamatinib Disodium in the Treatment of Warm Antibody Autoimmune Hemolytic Anemia

Warm Antibody Autoimmune Hemolytic Anemia

Spain, United States, Australia, Norway, Belarus, Germany, Netherlands, Belgium, Austria, Bulgaria, Czechia, France, Georgia, Italy, Russian Federation, Serbia, Ukraine, United Kingdom
Incyte Corporation

Terminated

Study of the Efficacy and Safety of Parsaclisib in Participants With Primary Warm Autoimmune Hemolytic Anemia (PATHWAY)

Warm Autoimmune Hemolytic Anemia (wAIHA)

Spain, United States, Austria, Belgium, Canada, France, Germany, Israel, Italy, Japan, Netherlands, Poland, United Kingdom
Apellis Pharmaceuticals, Inc.

Completed

Study to Assess the Safety, Tolerability, Efficacy and PK of APL-2 in Patients With Warm Type Autoimmune Hemolytic Anemia (wAIHA) or Cold Agglutinin Disease (CAD)

Cold Agglutinin Disease | Warm Autoimmune Hemolytic Anemia

United States
Rigel Pharmaceuticals

Completed

A Safety and Efficacy Study of R935788 in the Treatment of Warm Antibody Autoimmune Hemolytic Anemia (AIHA) (SOAR)

Warm Antibody Autoimmune Hemolytic Anemia

United States, Canada
Rigel Pharmaceuticals

Completed

A Phase 3, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Study of Fostamatinib Disodium in the Treatment of wAIHA

Warm Antibody Autoimmune Hemolytic Anemia

United States, Spain, Canada, Australia, Norway, France, Belarus, Germany, Netherlands, Belgium, United Kingdom, Austria, Czechia, Georgia, Italy, Russian Federation, Serbia, Ukraine, Romania, Denmark, Hungary, Bulgaria
Janssen Research & Development, LLC

Recruiting

Efficacy and Safety of M281 in Adults With Warm Autoimmune Hemolytic Anemia (ENERGY)

Warm Autoimmune Hemolytic Anemia

United States, Israel, Korea, Republic of, Spain, Czechia, France, Brazil, China, United Kingdom, Malaysia, Hungary, Japan, Poland, Germany, Ukraine, Italy, Greece, Netherlands, Egypt
Novartis Pharmaceuticals

Recruiting

A Study of Efficacy and Safety of Ianalumab in Previously Treated Patients With Warm Autoimmune Hemolytic Anemia (VAYHIA)

Warm Autoimmune Hemolytic Anemia (wAIHA)

China, Japan, Spain, Singapore, France, Germany, Taiwan, United States, Italy, India, Malaysia, Argentina, Hungary, Israel, Australia, Thailand, United Kingdom, Romania
Assistance Publique - Hôpitaux de Paris

Completed

Assessment of Tolerance of Mobilizing Peripheral Hematopoietic Stem Cells by Plerixafor in Sickle Cell Patients (DrepaMob)

Major Sickle Cell Syndrome of Type SS or Sβ Thalassemia

France
Assistance Publique - Hôpitaux de Paris
Mallinckrodt

Completed

Nitric Oxide Therapy for Acute Chest Syndrome in Sickle Cell Disease Children (INNOSTAPED)

Sickle Cell Disease | Acute Chest Syndrome

France
Assistance Publique - Hôpitaux de Paris

Completed

Combined Use of a Respiratory Broad Panel Multiplex PCR and Procalcitonin to Reduce Antibiotics Exposure in Hospitalized Sickle-cell Adults With Acute Chest Syndrome. (Antibio_STA)

Sickle Cell Disease | Acute Chest Syndrome

France
Soutien aux Actions contre les Maladies du Globule...
Pierre Fabre Laboratories; ADDMEDICA SASA

Recruiting

Validation of a Predictive Score of Acute Chest Syndrome (Presev2)

Acute Chest Syndrome | Vaso Occlusive Crisis

France
Centre Hospitalier Universitaire, Amiens

Recruiting

Prognostic Role of the Uremic Toxin Indoxyl Sulfate on Vascular and Cardiac Functions During Acute Kidney Injury (VASC-AKI)

Acute Kidney Injury | Cardiac Dysfunction | Vascular Dysfunction | Uremic; Toxemia | Cardiovascular Prognosis

France
Assistance Publique - Hôpitaux de Paris
LEO Pharma

Completed

Therapeutic Anticoagulation Strategy for Acute Chest Syndrome (TASC)

Anemia | Acute Chest Syndrome | Sickle Cell | Low-Molecular-Weight Heparin

France
Assistance Publique - Hôpitaux de Paris
Mallinckrodt

Completed

Effect of Inhaled Nitric Oxide in Acute Chest Syndrome (INOSTA Study) (INOSTA)

Sickle Cell Disease | Acute Chest Syndrome

France
University Hospital, Bordeaux

Recruiting

OBS'CEREVANCE: French Cohort of Pediatric Autoimmune Cytopenia (OBS'CEREVANCE)

Immune Thrombocytopenia | Autoimmune Hemolytic Anemia | Evans Syndrome

France
Novartis Pharmaceuticals

Completed

Study of Safety, Efficacy, Tolerability, Pharmacokinetics and Pharmacodynamics of LNP023 in in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Paroxysmal Nocturnal Hemoglobinuria (PNH) With Signs of Active Hemolysis

Italy, Germany, France
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Early-goal Directed Automated Red Blood Cell Exchange for Acute Chest Syndrome in Sickle Cell Disease (ARCAD)

Acute Chest Syndrome

France
Centre Hospitalier Universitaire, Amiens

Recruiting

Prognostic Value Serum Concentration of Indoxyl Sulfate During Acute Kidney Injury in Septic Shock Patients. (TOX-AKI)

Mortality | Septic Shock | Acute Kidney Injury | Uremic; Toxemia

France
Assistance Publique - Hôpitaux de Paris
Takeda Pharmaceuticals International, Inc.

Withdrawn

Efficacy and Safety of Ixazomib and Dexamethasone Refractory Autoimmune Cytopenia (Ixa-Cyto)

Immune Thrombocytopenia | Warm Autoimmune Hemolytic Anemia

France
Centre Hospitalier Universitaire, Amiens

Active, not recruiting

Detection of Acute Renal Failure Using Hospital Coding Data (IRA-PMSI)

Acute Renal Failure | Uremic Toxin | Iatrogenic Effect

France

Clinical Trials on Hemolytic-Uremic Syndrome in France

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