Clinical Trials on Hereditary Macular Degeneration

Total 55667 results

University Hospital "Sestre Milosrdnice"

Completed

The Association of the Peripheral Retinal Changes and Genotypic Changes in Patients With Age Related Macular Degeneration

Peripheral Retinal Degenerations, Age Related Macular Degeneration Polymorphisms
University of Illinois at Chicago

Completed

Treatment of Cystoid Macular Edema in Patients With Retinal Degeneration

Retinal Degenerations

United States
Institut de la Macula y la Retina
Igen BioLab SLU

Recruiting

Study to Evaluate the Response to Supplementation With Postbiotics in Patients With Macular Degeneration. (REVERS)

AMD | Drusen Stage Macular Degeneration | Soft Drusen | Reticular Pseudodrusen | Drusen (Degenerative) of Macula, Bilateral

Spain
Gemini Therapeutics, Inc.

Terminated

A Multiple Dose Study of Repeat Intravitreal Injections of GEM103 in Neovascular Age-related Macular Degeneration

Macular Degeneration | Retinal Degeneration | Neovascular Age-related Macular Degeneration | Retinal Disease

United States
Novartis Pharmaceuticals

Completed

Study to Collect Safety and ECG Data on Brolucizumab 6 mg Intravitreal Treatment in Patients With Wet AMD

Eye Diseases | Age-Related Macular Degeneration | Macular Degeneration | Retinal Degeneration | Retinal Diseases | Wet Macular Degeneration

United States, Puerto Rico
Tyrogenex
International Drug Development Institute; SynteractHCR

Terminated

X-82 to Treat Age-related Macular Degeneration

Eye Diseases | Macular Degeneration | Retinal Degeneration | Retinal Diseases | Age-Related Macular Degeneration (AMD) | Exudative Age-related Macular Degeneration | AMD | Macular Degeneration, Age-related, 10

United States
Xun Xu
Peking University; Zhongshan Ophthalmic Center, Sun Yat-sen University; Air Force... and other collaborators

Unknown

Pharmacogenomic Study on Anti-VEGF Medicine in Treatment of Macular Neovascular Diseases

Age-Related Macular Degeneration | Polypoidal Choroidal Vasculopathy | Pathological Myopia | Conbercept | Pharmacogenomic

China
University of Utah

Completed

Phase 1 Pilot Study of 4-MP to Treat Stargardt Macular Dystrophy

Macular Dystrophy, Corneal

United States
Federal University of São Paulo

Completed

Stem Cell Therapy for Outer Retinal Degenerations

Age Related Macular Degeneration | Exudative Age-related Macular Degeneration | Stargardt's Disease

Brazil
Escuela Neijing

Completed

Efficacy of Acupuncture in Macular Diseases (AMAD)

Age-related Macular Degeneration | Stargardt Disease | Macular Dystrophy

Colombia
Seoul Retina Investigator Group

Unknown

Early Vitrectomy for Macular Tractional Maculopathy

Myopia, Degenerative

Korea, Republic of
University of Southern California

Not yet recruiting

Non-invasive Ultrasound Retinal Stimulation for Vision Restoration

Age-Related Macular Degeneration | Retinitis Pigmentosa | Ultrasound Therapy; Complications
University of California, Davis

Active, not recruiting

Clinical Trial of Autologous Intravitreal Bone-marrow CD34+ Stem Cells for Retinopathy

Diabetic Retinopathy | Retinitis Pigmentosa | Non-exudative Age-related Macular Degeneration | Retina Vein Occlusion | Hereditary Macular Degeneration

United States
NGoggle
National Eye Institute (NEI); Duke University

Enrolling by invitation

Assessment of Visual Function With a Portable Brain-computer Interface

Glaucoma | Retinal Degeneration | Age Related Macular Degeneration | Optic Neuropathy

United States
Southeast Clinical Research Associates, LLC
Genentech, Inc.

Completed

Efficacy of Biweekly Ranibizumab (0.5 mg) for Exudative Macular Degeneration Retinal Edema Refractory to Anti-VEGF

Exudative Age Related Macular Degeneration

United States
Medical University of Vienna

Unknown

Objective Assessment of Macular Function at Retinal and Cortical Levels

Retina Disorder | Macula; Degeneration, Congenital or Hereditary
Wake Forest University Health Sciences

Terminated

Descemet Membrane Endothelial Keratoplasty vs. Descemet's Stripping With Endothelial Keratoplasty vs. Descemet Stripping Only

Fuchs Dystrophy | Cystoid Macular Edema

United States
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

CB-PRP in Retinitis Pigmentosa and Dry Age-related Macular Degeneration (SiCord)

Retinitis Pigmentosa | Dry Age-related Macular Degeneration

Italy
Centre Hospitalier Intercommunal Creteil
Bayer

Completed

Aflibercept After Ranibizumab in Exudative Age-related Macular Degeneration (ARI2)

Eye Diseases | Macular Degeneration | Retinal Degeneration | Retinal Diseases | Wet Macular Degeneration

France
Pomeranian Medical University Szczecin

Unknown

Stem Cells Therapy in Degenerative Diseases of the Retina

Retinal Degeneration | Retinitis Pigmentosa | Age Related Macular Degeneration | Stargardt Disease 1

Poland
Astellas Institute for Regenerative Medicine

Completed

Sub-retinal Transplantation of hESC Derived RPE(MA09-hRPE)Cells in Patients With Stargardt's Macular Dystrophy

Stargardt's Macular Dystrophy

United States
Astellas Institute for Regenerative Medicine

Completed

Long Term Follow Up of Sub-retinal Transplantation of hESC Derived RPE Cells in Stargardt Macular Dystrophy Patients

Stargardt's Macular Dystrophy

United States
Tufts University
American Pistachio Growers

Recruiting

Pistachios and Neural Macular Pigment

Eye Diseases | Macular Degeneration | Retinal Degeneration | Retinal Diseases

United States
National Eye Institute (NEI)

Completed

Effect of DHA Supplements on Macular Function in Patients With Stargardt Macular Dystrophy and Stargardt-like Macular Dystrophy

Macular Degeneration

United States
CHABiotech CO., Ltd

Completed

Safety and Tolerability of MA09-hRPE Cells in Patients With Stargardt's Macular Dystrophy(SMD)

Stargardt's Macular Dystrophy

Korea, Republic of
Astellas Institute for Regenerative Medicine

Completed

Safety and Tolerability of Sub-retinal Transplantation of Human Embryonic Stem Cell Derived Retinal Pigmented Epithelial (hESC-RPE) Cells in Patients With Stargardt's Macular Dystrophy (SMD)

Stargardt's Macular Dystrophy

United Kingdom
Astellas Institute for Regenerative Medicine

Completed

A Follow up Study to Determine the Safety and Tolerability of Sub-retinal Transplantation of Human Embryonic Stem Cell Derived Retinal Pigmented Epithelial (hESC-RPE) Cells in Patients With Stargardt's Macular Dystrophy (SMD)

Stargardt's Macular Dystrophy

United Kingdom
Southwest Hospital, China

Unknown

Clinical Study of Subretinal Transplantation of Human Embryo Stem Cell Derived Retinal Pigment Epitheliums in Treatment of Macular Degeneration Diseases

Macular Degeneration | Stargardt's Macular Dystrophy

China
Institute of Molecular and Clinical Ophthalmology...

Recruiting

Function and Imaging Assessments for G1961E-associated Stargardt Disease (FIRSTORBIT)

Stargardt Disease | Stargardt Disease 1 | Fundus Flavimaculatus | Macular Degeneration, Stargardt | Macular Dystrophy With Flecks, Type 1

Switzerland
Novartis Pharmaceuticals

Terminated

The Efficacy of Oral Everolimus in Patients With Neovascular Age-related Macular Degeneration

Age-related Macular Degeneration | Choroidal Neo-Vascular Age-onset Macular Degeneration

United Kingdom, United States
Gemini Therapeutics, Inc.

Completed

First in Human Study to Evaluate the Safety and Tolerability of GEM103 in Geographic Atrophy Secondary to Dry Age Related Macular Degeneration

Macular Degeneration | Retinal Degeneration | Geographic Atrophy | Dry Age-related Macular Degeneration | Retinal Disease

United States
Retina Foundation of the Southwest

Completed

Rod Sensitivity in Age-related Macular Degeneration (AMD) and Retinitis Pigmentosa (RP)

Retinitis Pigmentosa | AMD

United States
Alkeus Pharmaceuticals, Inc.

Completed

Phase 1 Safety Study of ALK-001 in Healthy Volunteers

Age-related Macular Degeneration | Stargardt Disease | Other Retinal Dystrophies
Johns Hopkins University

Completed

Bevicizumab (Avastin) Infusion for Choroidal Neovascularization (CNV) Not Associated With Age-Related Macular Degeneration (AMD)

Choroidal Neovascularization | Pathological Myopia | Degenerative Myopia
Manhattan Eye, Ear & Throat Hospital
Alcon Research

Completed

Treatment of Conditions With Open Label-Anecortave Acetate Sterile Suspension ( 15mg.) Where Lesions do Not Meet Acceptable Criteria for Standard Care.

Age-Related Macular Degenerations. | Subfoveal Neovascularization.

United States
Gemini Therapeutics, Inc.

Terminated

A Multiple Dose Study of Repeat Intravitreal Injections of GEM103 in Dry Age-related Macular Degeneration

Macular Degeneration | Retinal Degeneration | Geographic Atrophy | Dry Age-related Macular Degeneration | Retinal Disease

United States
Ocugen

Recruiting

Study to Assess the Safety and Efficacy of OCU410ST for Stargardt Disease (GARDian)

Stargardt Disease

United States
Osias Francisco de Souza

Unknown

Evaluation of Changes in the Parameters of Optical Coherence Tomography After Intravitreal Injection of Lucentis

Degeneration of Macula and Posterior Pole

Brazil
Benha University

Recruiting

BEOVU Versus Eylea in the Treatment of Age-related Macular Neovascular Degeneration

Macula Lutea Degeneration

United Arab Emirates
Alkeus Pharmaceuticals, Inc.

Recruiting

Phase 2 Tolerability and Effects of ALK-001 on Stargardt Disease (TEASE)

Stargardt Disease | Stargardt Macular Degeneration | Stargardt Macular Dystrophy | Autosomal Recessive Stargardt Disease 1 (ABCA4-related)

United States
Alkeus Pharmaceuticals, Inc.

Enrolling by invitation

Open-Label Extension: Tolerability and Effects of ALK-001 on Stargardt Disease (TEASE)

Stargardt Disease | Stargardt Macular Degeneration | Stargardt Macular Dystrophy | Autosomal Recessive Stargardt Disease 1 (ABCA4-related)

United States
Columbia University
National Eye Institute (NEI); Centre Hospitalier National d'Ophtalmologie des... and other collaborators

Recruiting

Study of BEST1 Vitelliform Macular Dystrophy

Retinitis Pigmentosa | Best Vitelliform Macular Dystrophy

United States, Germany, France
University Hospital Tuebingen

Completed

Stargardt Disease in Childhood

Stargardt Disease

Germany
RBP4 Pty Ltd
Belite Bio, Inc

Completed

This is a Dose-finding Study Followed by 2-year Extension Study to Evaluate Safety and Tolerability of Tinlarebant in Adolescent Subjects With Stargardt Disease

Stargardt Disease

Taiwan, Australia
Nanoscope Therapeutics Inc.

Completed

Safety and Effects of a Single Intravitreal Injection of vMCO-010 Optogenetic Therapy in Subjects With Stargardt Disease (STARLIGHT)

Stargardt Disease

United States
Nanoscope Therapeutics Inc.

Enrolling by invitation

Non-interventional Long Term Follow-up Study of Participants Previously Enrolled in the STARLIGHT Study (SUSTAIN)

Stargardt Disease

United States
Pfizer

Completed

Safety And Tolerability Study Of RN6G In Patients With Dry, Age-Related Macular Degeneration

Eye Diseases | Macular Degeneration | Retinal Degeneration | Age-Related Maculopathies | Age-Related Maculopathy

United States
Ophthalmos Research and Education Institute

Completed

Therapeutic Potential of Omega-3 Fatty Acids Supplementation in Dry Macular Degeneration and Stargardt Disease (MADEOS)

Stargardt Disease 1 | Dry AMD

France, Germany, Italy
Catholic University of the Sacred Heart

Unknown

Saffron Supplementation in Stargardt's Disease (STARSAF02)

Retinal Degeneration | Genetic Disease | Single-Gene Defects | Macular Dystrophy

Italy
Sanofi

Active, not recruiting

Phase I/II Follow-up Study of SAR422459 in Patients With Stargardt's Macular Degeneration

Stargardt's Disease

United States, France

Clinical Trials on Hereditary Macular Degeneration

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