Clinical Trials on High Risk Atherosclerotic Cardiovascular Disease in Singapore

Total 516 results

National University Hospital, Singapore
National University of Singapore

Unknown

Intima-Medial Thickness Guidance of Primary Prevention in Relatives of Patients With Early onSet Atherosclerosis (IMPRESS)

Cardiovascular Disease | Atherosclerotic Cardiovascular Disease

Singapore
Singapore General Hospital

Active, not recruiting

Prospective Registry to Investigate the Safety and Efficacy of the Treatment With the Selution Sirolimus Drug Coated Balloon in TASC C and D Atheroma-occlusive Infra-Inguinal Disease in Patients With Chronic Limb Threatening Ischemia From Singapore (PRISTINE)

Peripheral Artery Disease | Critical Lower Limb Ischemia

Singapore
Singapore General Hospital

Recruiting

Efficacy and Safety of Endovenous Radio Frequency (EVRF) for Treatment of Varicose Veins in Singapore (ESVS)

Varicose Veins | Venous Reflux | Chronic Venous Insufficiency

Singapore
Singapore National Eye Centre
Bayer

Completed

An Open Label-study to Compare the Efficacy of Aflibercept Monotherapy for Polypoidal Choroidal Vasculopathy

Age Related Macular Degeneration | Polypoidal Choroidal Vasculopathy

Singapore
Paul Ong

Unknown

Feasibility Trial Evaluating Efficacy and Safety of Solitaire™ Thrombus Retrieval Device in the Management of Refractory Thrombus in Patients With Acute Coronary Syndrome (Solitaire)

Refractory Thrombus in Patients With Acute Coronary Syndrome

Singapore
National Heart Centre Singapore

Unknown

Targeting Mitochondrial Fusion and Fission to Prevent Atherosclerosis: Getting the Balance Right (MITOFFA)

CAD Patients

Singapore
Changi General Hospital

Approved for marketing

Athrectomy and Drug Eluting Balloon Therapy (ADEBT) on the Femoral Popliteal Arteries (ADEBT)

Peripheral Arterial Disease

Singapore
Clinical Nutrition Research Centre, Singapore

Completed

The Effect of Different States of Lipid in Food on Glycaemia, Lipaemia and Insulinaemia.

Diabetes Mellitus, Type 2 | Cardiovascular Risk Factor

Singapore
Concept Medical Inc.

Completed

Clinical Use and Safety of the Xtreme Touch (Magic Touch PTA)- Neo Sirolimus Coated PTA Balloon Catheter in the Treatment of Infrainguinal Peripheral Arterial Disease (XTOSI)

Atherosclerosis | Peripheral Artery Disease

Singapore
Sengkang General Hospital

Recruiting

Promus PREMIER Below The Knee Registry

Peripheral Arterial Disease | Arterial Disease | Arterial Disease of Legs

Singapore
Concept Medical Inc.

Recruiting

ABLUMINUS DES BTK Registry - FIM

Atherosclerosis | Peripheral Artery Disease | Arterial Disease of Legs

Singapore
Singapore General Hospital
Tan Tock Seng Hospital; Duke-NUS Graduate Medical School; Singapore Clinical...

Completed

Singapore INfra-Genicular Angioplasty With PAclitaxel-eluting Balloon for Critical Limb Ischaemia (SINGA-PACLI) Trial (SINGA-PACLI)

Peripheral Arterial Disease

Singapore
Novartis Pharmaceuticals

Recruiting

A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients.

Primary Prevention of Atherosclerotic Cardiovascular Disease

United States, China, Italy, Spain, Canada, France, Netherlands, Switzerland, Taiwan, Greece, Thailand, Brazil, India, Hungary, Latvia, Mexico, Israel, Turkey, Argentina, Singapore, Australia, Belgium, Bulgaria, Denmark, Croatia, South Africa and more
Singapore General Hospital

Recruiting

Evaluation of Post-Angioplasty Outcomes

Peripheral Arterial Disease | Critical Limb Ischemia

Singapore
Novartis Pharmaceuticals

Active, not recruiting

Study of Inclisiran to Prevent Cardiovascular (CV) Events in Participants With Established Cardiovascular Disease (VICTORION-2P)

Atherosclerotic Cardiovascular Disease

United States, China, South Africa, Spain, Austria, Belgium, Croatia, Estonia, Hungary, Taiwan, Turkey, Netherlands, Italy, Australia, Czechia, Denmark, France, Israel, Korea, Republic of, Thailand, Argentina, Bulgaria, Greece, Romania, Sloveni... and more
KK Women's and Children's Hospital
Actxa Pte Ltd

Completed

Calibration and Evaluation of Non-Invasive Wireless Blood Glucose Monitoring

Blood Glucose, High | Blood Glucose, Low

Singapore
Singapore ETH Centre
Nanyang Technological University; ETH Zurich; National University of Singapore

Recruiting

The LvL UP Pilot Trial

Health Behavior | Noncommunicable Diseases | Mental Health Issue | Lifestyle Risk Reduction

Singapore
Singapore General Hospital
National University Hospital, Singapore

Unknown

Investigating the Safety and Efficacy of the Treatment With the Non-compliant Jade Balloon in TASC C and D Athero-occlusive Infra-inguinal Disease in Patients With Chronic Limb Threatening Limb Ischemia From SingaporE (PINNACLE)

Peripheral Artery Disease | Critical Limb Ischemia

Singapore
National Heart Centre Singapore
National University Hospital, Singapore; Khoo Teck Puat Hospital; Singapore General...

Not yet recruiting

REducing Diabetic macrovascUlar Complications duE to Peripheral Arterial Disease- REDUCE-PAD (REDUCE-PAD)

Diabetes Mellitus, Type 2 | Peripheral Arterial Disease

Singapore
ECRI bv
University of Bern; European Cardiovascular Research Center; Terumo Medical Corporation and other collaborators

Completed

Management of High Bleeding Risk Patients Post Bioresorbable Polymer Coated Stent Implantation With an Abbreviated Versus Prolonged DAPT Regimen (MASTER DAPT)

Coronary Artery Disease | PCI | High Bleeding Risk

Netherlands, France, United Kingdom, Australia, Singapore, Japan, Italy, Poland, Spain, Switzerland, Israel, Argentina, Austria, Bahrain, Bangladesh, Belgium, Bulgaria, Czechia, Denmark, Estonia, Germany, Hungary, India, Korea, Republic... and more
Brigham and Women's Hospital
National Institute of Mental Health (NIMH); Yale University; Orygen

Recruiting

AMP SCZ® Observational Study: PREDICT-DPACC (AMP SCZ)

Psychosis | Remission | Conversion | Clinical High Risk

United States, United Kingdom, Canada, Italy, Australia, Chile, China, Denmark, Germany, Hong Kong, Korea, Republic of, Singapore, Spain, Switzerland
Sanofi
Regeneron Pharmaceuticals

Completed

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab

Atherosclerotic Cardiovascular Disease

China, Hong Kong, Austria, Bulgaria, Norway, Peru, France, Japan, Spain, Lithuania, Philippines, Israel, Belgium, Croatia, Poland, Hungary, Chile, Mexico, Latvia, Singapore, Switzerland, Colombia, Greece, Ukraine, Turkey, Finland, United States and more
Boston Scientific Corporation

Completed

NG PROMUS Stent System for the Treatment of Atherosclerotic Coronary Lesions

Coronary Artery Disease | Atherosclerosis

Singapore, Australia, New Zealand
Novartis Pharmaceuticals

Terminated

Phase III Study Investigating the Efficacy and Safety of Ruxolitinib in Early Myelofibrosis Patients With High Molecular Risk Mutations. (ReTHINK)

Myelofibrosis With High Molecular Risk Mutations

Belgium, Spain, United Kingdom, Hungary, Italy, Japan, Taiwan, Germany, Canada, Singapore, Austria, Australia, France, Israel, Sweden, Switzerland, Hong Kong, Greece, Turkey, Brazil, Russian Federation, Denmark, Portugal, Norway, Poland
Singapore General Hospital
National Medical Research Council (NMRC), Singapore

Completed

Autologous Cytokine-induced Killer Cell Adoptive Immunotherapy for Acute Myeloid Leukemia and Myelodysplastic Syndrome

Acute Myeloid Leukemia | Myelodysplastic Syndrome, High Grade

Singapore
Concept Medical Inc.

Recruiting

Sirolimus Coated Balloon Versus Standard Balloon for SFA and Popliteal Artery Disease (FUTURE-SFA)

Atherosclerosis | Peripheral Artery Disease | Arterial Disease

Singapore, Korea, Republic of, Taiwan
National University, Singapore

Completed

Relationship Between Obstructive Sleep Apnea and Coronary Atherosclerosis (IDEAS-OSA)

Coronary Artery Disease | Obstructive Sleep Apnea

Singapore
KK Women's and Children's Hospital
Lien Foundation

Recruiting

Healthy Early Life Moments in Singapore (HELMS)

Mental Health Wellness 1 | Metabolic Disease | Maternal Obesity | Lifestyle Risk Reduction

Singapore
National University Hospital, Singapore
National University of Singapore

Unknown

A Culture-Centered Approach to Promoting Women's Heart Health in Singapore (WHH)

Cardiovascular Disease

Singapore
Concept Medical Inc.

Recruiting

SirolimUs CoaTed Balloon for The TrEatment of Below The Knee Arterial Disease (FUTURE-BTK)

Atherosclerosis | Peripheral Artery Disease | Arterial Disease of Legs

Singapore, Korea, Republic of, Taiwan
National Heart Centre Singapore
Duke-NUS Graduate Medical School

Completed

EaRneST: Exercise and CiRulating MetabolomicS: A Pilot Randomized Controlled Study (EaRneST)

Cardiovascular Disease Other

Singapore
Novartis Pharmaceuticals

Active, not recruiting

HDM201 in Combination With MBG453 or Venetoclax in Patients With Acute Myeloid Leukemia (AML) or High-risk Myelodysplastic Syndrome (MDS)

Acute Myeloid Leukemia (AML) | High-risk Myelodysplastic Syndrome (MDS)

Spain, Singapore, Australia, Germany, Italy, Finland, United States
Vascuros Medical Pte Ltd
Novella Clinical

Unknown

The VaSecure BTK Study

Peripheral Arterial Occlusive Disease | Peripheral Vascular Disease | Peripheral Artery Disease

Singapore, Belgium, Germany
Alexandra Hospital
National University Hospital, Singapore

Active, not recruiting

Evaluating a Preventive Heart Health Programme for Women at Midlife (Phenomenon)

Cardiovascular Disease | Menopause

Singapore
Duke-NUS Graduate Medical School
SingHealth Polyclinics

Unknown

Management of Hypertension and Multiple Risk Factors to Enhance Cardiovascular Health

Hypertension | Cardiovascular Disease

Singapore
Clinical Nutrition Research Centre, Singapore

Completed

Liquid or Solid State of Food on Glycaemia, Lipaemia and Insulinaemia

Cardiovascular Disease | Diabetes

Singapore
National University Hospital, Singapore

Unknown

Epimedium Prenylflavonoid (EP) Extract for Osteoporosis and Cardiovascular Disease

Cardiovascular Disease | Osteoporosis

Singapore
Nanyang Technological University
National University Health System, Singapore; National University of Singapore

Recruiting

Healthy Living With Online suPport & Education for Cardiovascular Disease in the Primary Care Setting (HOPE-CVD-GP)

Cardiovascular Diseases (CVD)

Singapore
Clinical Nutrition Research Centre, Singapore
Glico Asia Pacific Pte Ltd

Completed

To Study the Effects of Co-ingesting Different Forms of Almond, Almond Paste, Fibre, and Almond Phytochemicals With Bread on Postprandial Glucose and Insulin Profiles

Cardiovascular Diseases | Metabolic Disease

Singapore
Tan Tock Seng Hospital

Unknown

Effectiveness of a Novel Mobile App Based Cardiac Rehabilitation

Cardiac Disease

Singapore
National Heart Centre Singapore

Unknown

Study of RV Remodeling in Congenital Heart Disease (RVShape)

Congenital Heart Disease

Singapore
Cordis Corporation

Terminated

Feasibility Study With the Sirolimus-Eluting BX Velocity Balloon-Expandable Stent in the Treatment of Diabetic Patients With Native Coronary Artery Lesions (DECODE)

Peripheral Vascular Diseases

United States, China, Malaysia, India, Singapore
National Heart Centre Singapore

Unknown

E_Stethoscope: Portable Digital Auscultation Study on Hypertensive/Hypertensive Heart Disease Patients

Hypertension | Hypertensive Heart Disease

Singapore
KK Women's and Children's Hospital

Completed

A Novel Closed-loop Integrated System for the Maintenance of Haemodynamic Stability (DIVA)

Hypotension

Singapore
Duke-NUS Graduate Medical School

Completed

Management of Hypertension and Multiple Risk Factors to Enhance Cardiovascular Health

Cardiovascular Diseases | Hypertension

Singapore
National University of Singapore
National University Hospital, Singapore; Ministry of Education, Singapore

Completed

Cardio-vascular Protective Effects of Wolfberry in Middle-aged and Older Adults

Cardiovascular Diseases | Aging

Singapore
National University of Singapore
University Health Network, Toronto; National University Hospital, Singapore; Singapore... and other collaborators

Recruiting

HOPE-CVD-Virtual: A Virtual Trial to Evaluate the Primary Prevention of CVD

Cardiovascular Diseases

Singapore
National Cancer Centre, Singapore
Khoo Teck Puat Hospital; National Heart Centre Singapore

Not yet recruiting

Timely Interventions to Enable and Reach Patients With Heart Failure, and Their Caregivers With Palliative Care (TIER-HF-PC)

Heart Failure

Singapore
National Heart Centre Singapore
National University Hospital, Singapore; Khoo Teck Puat Hospital; Singapore General... and other collaborators

Completed

Asian neTwork for Translational Research and Cardiovascular Trials ("ATTRaCT")

Heart Failure

Singapore
National Cancer Centre, Singapore
National Medical Research Council (NMRC), Singapore; Ministry of Health, Singapore

Active, not recruiting

ENABLE (Educate, Nurture, Advise, Before Life Ends) Intervention for Heart Failure (HF) Patients and Their Caregivers in Singapore (ENABLE-HF-SG)

Heart Failure

Singapore

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