Clinical Trials on Histiocytic Disorders

Total 144431 results

Mayo Clinic

Recruiting

Clinical and Molecular Characteristics of Histiocytic Disorders

Histiocytic Disorder

United States
Memorial Sloan Kettering Cancer Center
Genentech, Inc.

Completed

Single-agent Cobimetinib for Adults With Histiocytic Disorders

Histiocytic Disorders

United States
Memorial Sloan Kettering Cancer Center
BioMed Valley Discoveries, Inc

Recruiting

Ulixertinib in People With Histiocytic Neoplasms

Histiocytic Neoplasms

United States
Dana-Farber Cancer Institute
Celgene

Active, not recruiting

A Study of Lenalidomide for Adult Histiocyte Disorders

Langerhans Cell Histiocytosis (LCH) | Histiocytoses Erdheim-chester Disease | Histiocytic Sarcoma (HS)

United States
Dana-Farber Cancer Institute
Merck Sharp & Dohme LLC

Suspended

Pembrolizumab in Neoplasms or Lymphomas

Lymphoma | Histiocytic Sarcoma | Follicular Dendritic Cell Sarcoma | Interdigitating Dendritic Cell Sarcoma

United States
Far Eastern Memorial Hospital

Unknown

Ultrasonographic Differentiation Between Kikuchi's Disease and Lymphoma in Patients With Cervical Lymphadenopathy

Lymphoma | Kikuchi's Disease

Taiwan
University of Alabama at Birmingham

Recruiting

Histiocytic Disorder Follow-up Study

Histiocytosis | Langerhans Cell Histiocytosis | Erdheim-Chester Disease | Rosai Dorfman Disease | Xanthogranuloma | Malignant Histiocytoses

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Low-Dose Selinexor and Choline Salicylate for Non-Hodgkin or Hodgkin Lymphoma, Histiocytic/Dendritic Cell Neoplasm, or Relapsed or Refractory Multiple Myeloma

Recurrent Hodgkin Lymphoma | Refractory Hodgkin Lymphoma | Refractory Plasma Cell Myeloma | Recurrent Histiocytic and Dendritic Cell Neoplasm | Recurrent Non-Hodgkin Lymphoma | Refractory Histiocytic and Dendritic Cell Neoplasm | Refractory Non-Hodgkin Lymphoma | Recurrent Plasma Cell Myeloma

United States
Gilead Sciences

Completed

Safety Study of Different Doses of hA20 (Veltuzumab) in CD20+ Non-Hodgkin's Lymphoma

Non-Hodgkin's Lymphoma | Lymphoma, Diffuse | Lymphoma, Diffuse, Mixed Lymphocytic-Histiocytic

France, United Kingdom
Carl Allen
Baylor College of Medicine; Genentech, Inc.; North American Consortium for Histiocytosis

Recruiting

Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders (NACHO-COBI)

Histiocytic Sarcoma | Juvenile Xanthogranuloma | Histiocytic Disorders, Malignant | Erdheim-Chester Disease | Langerhan's Cell Histiocytosis | Rosai Dorfman Disease | Neuro-Degenerative Disease

United States
Memorial Sloan Kettering Cancer Center

Completed

Uptake and Biodistribution of 18F-fluorocholine in Histiocytic Disorders by PET Imaging and Biopsy Measurement

Langerhans Cell Histiocytosis | Erdheim-Chester Disease | Histiocytic Disorders

United States
Memorial Sloan Kettering Cancer Center
Pentixapharm AG

Recruiting

In-Human CXCR4 Imaging of Blood Cancers Using [68Ga]-Pentixafor-PET

Multiple Myeloma | Non-Hodgkin Lymphoma | Erdheim-Chester Disease | Rosai-Dorfman Disease | Histiocytic Neoplasms

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Exploration of Allograft Humoral Rejection in Chronic Histiocytic Intervillositis (RH-PL)

Miscarriage | Intrauterine Growth Retardation | Chronic Histiocytic Intervillositis | Fetal Death in Utero

France
Maria Sklodowska-Curie National Research Institute...

Unknown

Hypofractionated Radiotherapy With Sequential Chemotherapy in Marginally Resectable Soft Tissue Sarcomas of Extremities or Trunk Wall (UN-RESARC)

Sarcoma | Leiomyosarcoma | Fibrosarcoma | Liposarcoma | Myxoid Liposarcoma | Myosarcoma | Histiocytic Sarcoma | Pleomorphic Liposarcoma | Synovial Sarcoma | Undifferentiated Pleomorphic Sarcoma | Myxofibrosarcoma | Dedifferentiated Liposarcoma | Malignant Peripheral Nerve Sheath Tumors | Malignant Triton Tumor | Pleomorphic... and other conditions

Poland
Children's Hospital Medical Center, Cincinnati

Recruiting

Mirdametinib in Histiocytic Disorders

Histiocytic Disorders | Juvenile Xanthogranuloma (JXG) | Langerhans Cell Histiocytosis (LCH) | Rosai-Dorfman Disease (RDD)

United States
Patrick C. Johnson, MD
AstraZeneca

Recruiting

Acalabrutinib + Liso-Cel In R/R Aggressive B-Cell Lymphomas

Refractory B-Cell Non-Hodgkin Lymphoma | Diffuse Large B-cell Lymphoma (DLBCL) | Grade 3b Follicular Lymphoma | Refractory Aggressive B-cell Lymphomas | Aggressive B-cell NHL | De Novo or Transformed Indolent B-cell Lymphoma | DLBCL, Nos Genetic Subtypes | T Cell/Histiocyte-rich Large B-cell Lymphoma and other conditions

United States
The Hospital for Sick Children

Active, not recruiting

International Rare Histiocytic Disorders Registry (IRHDR) (IRHDR)

Rare Histiocytic Disorders (RHDs) | Juvenile Xanthogranuloma (JXG) | Reticulohistiocytoma (Epithelioid Histiocytoma) | Xanthoma Disseminatum (XD) | Multicentric Reticulohistiocytosis (MRH) | Systemic Juvenile Xanthogranuloma | Erdheim-Chester Disease (ECD) | Multi-system Rosai-Dorfman Disease (RDD)

Canada, United States, Poland, Argentina, Austria, Czechia, Germany, Italy, Russian Federation, Spain
SpringWorks Therapeutics, Inc.

Available

Individual Patient Compassionate Use of Mirdametinib

Neurofibromatosis Type 1-Associated Plexiform Neurofibromas | Histiocytic Neoplasm | Other MAP-K Pathway Driven Diseases
Northwestern University
National Cancer Institute (NCI)

Recruiting

Zanubrutinib and CAR T-cell Therapy for the Treatment of Recurrent or Refractory Aggressive B-cell Non-Hodgkin's Lymphoma or Transformed Indolent B-cell Lymphoma

Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Recurrent... and other conditions

United States
Center for International Blood and Marrow Transplant...
National Marrow Donor Program

Recruiting

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

Autoimmune Diseases | Hodgkin Lymphoma | Hematologic Malignancies | Acute Lymphoblastic Leukemia (ALL) | Non-hodgkin Lymphoma | Severe Aplastic Anemia | Inherited Disorders of Metabolism | Inherited Abnormalities of Platelets | Histiocytic Disorders | Acute Myelogenous Leukemia (AML or ANLL) | Other Acute... and other conditions

United States
Northwestern University
Bristol-Myers Squibb; National Cancer Institute (NCI)

Suspended

Nivolumab and Combination Chemotherapy in Treating Participants With Diffuse Large B-Cell Lymphoma

B-Cell Non-Hodgkin Lymphoma | Primary Mediastinal (Thymic) Large B-Cell Lymphoma | CD20 Positive | Aggressive Non-Hodgkin Lymphoma | Transformed Follicular Lymphoma to Diffuse Large B-Cell Lymphoma | Diffuse Large B-Cell Lymphoma Unclassifiable | Intravascular Large B-Cell Lymphoma | T-Cell/Histiocyte-Rich...

United States
Northwestern University
National Cancer Institute (NCI)

Active, not recruiting

Combination Chemotherapy and TAK-659 as Front-Line Treatment in Treating Patients With High-Risk Diffuse Large B Cell Lymphoma

Diffuse Large B-Cell Lymphoma | Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | High Grade B-Cell Lymphoma, Not Otherwise Specified | T-Cell/Histiocyte-Rich Large B-Cell Lymphoma | High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements | Diffuse Large B-Cell Lymphoma... and other conditions

United States
Jennifer Crombie, MD
Merck Sharp & Dohme LLC

Recruiting

Pembro Plus CAR T-cell Therapy in R/R in PMBCL

Primary Mediastinal Large B-cell Lymphoma (PMBCL) | Primary Mediastinal Large B Cell Lymphoma | T-Cell/Histiocyte-Rich Large B-Cell Lymphoma | Primary Mediastinal Large B-Cell Lymphoma Refractory | Primary Mediastinal Large B-Cell Lymphoma Recurrent | Epstein-Barr Virus Positive Diffuse Large...

United States
David Bond, MD

Recruiting

Tafasitamab and Lenalidomide Followed by Tafasitamab and ICE as Salvage Therapy for Transplant Eligible Patients With Relapsed/ Refractory Large B-Cell Lymphoma

Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Recurrent... and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

TTI-622 and TTI-621 in Combination With Pembrolizumab for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Recurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Recurrent Diffuse Large B-Cell... and other conditions

United States
University of Michigan

Completed

Sleep-Disordered Breathing and PAP in Perinatal Depression

Major Depressive Disorder | Sleep-disordered Breathing

United States
Black Diamond Therapeutics, Inc.

Recruiting

A Study of BDTX-4933 in Patients With KRAS, BRAF and Select RAS/MAPK Mutation-Positive Cancers

Melanoma | Colorectal Cancer | NSCLC | Solid Tumor | Metastatic Lung Cancer | Metastatic Lung Non-Small Cell Carcinoma | Metastatic Melanoma | Non-small Cell Lung Cancer | Histiocytosis | Melanoma (Skin) | Recurrent Melanoma | Thyroid Carcinoma | Thyroid Cancer | Brain Metastases | Recurrent Histiocytic and Dendritic... and other conditions

United States
University Hospital, Montpellier

Recruiting

Evaluation of a Parent/Child Cognitive-Behaviorial Therapy Program in ADHD Children With Emotional Dysregulation Profile (DP-KID)

Attention Deficit Disorder With Hyperactivity | Attention-Deficit-Disordered Children

France
Adams Clinical

Recruiting

Triage Survey for Psychiatry Research Eligibility (TRIAGE-Psych)

Generalized Anxiety Disorder | Major Depressive Disorder | Borderline Personality Disorder

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Imagery Rescripting as a Stand-alone Treatment for OCD and BDD.

Obsessive-Compulsive Disorder | Anxiety Disorders | Body Dysmorphic Disorders

Netherlands
Weill Medical College of Cornell University

Completed

The Influence of the Menstrual Cycle on Lithium and Sertraline Blood Levels

Schizoaffective Disorder | Obsessive-Compulsive Disorder | Major Depressive Disorder | Posttraumatic Stress Disorder | Social Anxiety Disorder | Panic Disorder | Premenstrual Dysphoric Disorder | Dysthymic Disorder | Cyclothymic Disorder | Bipolar Affective Disorders

United States
Nova Scotia Health Authority

Terminated

Cognitive Behavioral Therapy Group for Older Adults Delivered by Telethealth

Generalized Anxiety Disorder | Major Depressive Disorder | Social Anxiety Disorder | Panic Disorder

Canada
Sheba Medical Center

Recruiting

Development of a Model for Digital Monitoring of the Mental State of the Hospitalized Patient

Personality Disorders | Depressive Disorder | Mood Disorders | Schizophrenia | Schizoaffective Disorder | Anxiety Disorders | Bipolar Disorder | Severe Mental Disorder | Psychotic Episode

Israel
Laureate Institute for Brain Research, Inc.
National Center for Complementary and Integrative Health (NCCIH)

Active, not recruiting

Floatation-REST (Reduced Environmental Stimulation Therapy) for Anxiety and Depression

Generalized Anxiety Disorder | Major Depressive Disorder | Posttraumatic Stress Disorder | Social Anxiety Disorder | Panic Disorder | Agoraphobia

United States
Medical University of Gdansk

Enrolling by invitation

Observation of Ketamine Treatment Safety and Tolerability in Adult Psychiatry Clinic Medical University of Gdańsk Inpatients (KetGD)

Obsessive-Compulsive Disorder | Anxiety Disorders | Somatoform Disorders | Post Traumatic Stress Disorder | Major Depressive Disorder | Dissociative Disorder

Poland
Vivantes Netzwerk für Gesundheit GmbH
Medizinische Hochschule Brandenburg Theodor Fontane; Vivantes Klinikum am Urban and other collaborators

Active, not recruiting

Implementation, Efficacy and Costs of Inpatient Equivalent Home-Treatment in German Mental Health Care (AKtiV)

Personality Disorders | Anxiety Disorders | Addiction | Schizo Affective Disorder | Mental Disorder | Eating Disorders

Germany
Samsung Medical Center

Unknown

The Development of Skin Adhesive Patches for the Monitoring and Prediction of Mental Disorders

Major Depressive Disorder, Anxiety Disorder

Korea, Republic of
King's College London
Innovate UK; Juniver

Recruiting

Efficacy of Juniver, a Digital Self-help Intervention, on Symptoms of Eating Disorders: A Randomised Controlled Trial

Anorexia Nervosa | Feeding and Eating Disorders | Binge-Eating Disorder | Bulimia Nervosa | Binge Eating | Eating Disorders | Disordered Eating

United Kingdom
Centre Hospitalier Intercommunal Creteil
University of Paris 5 - Rene Descartes

Terminated

School Withdrawal in Adolescents (DESCOL)

Depression | Obsessive-Compulsive Disorder | Anxiety Disorders | Somatoform Disorders | Emotional Disorder | Behavior Disorders | Neurotic Disorders

France
Laureate Institute for Brain Research, Inc.

Completed

Examining the Effects of Reduced Environmental Stimulation on Anxiety

Generalized Anxiety Disorder | Major Depressive Disorder | Social Anxiety Disorder | Panic Disorder | Agoraphobia | PostTraumatic Stress Disorder

United States
Columbia University

Not yet recruiting

Self-Distancing for Pediatric Anxiety and OCD

Obsessive-Compulsive Disorder | Anxiety Disorders

United States
National Institute of Mental Health (NIMH)
University of Oregon; University of Maryland; University of Minnesota

Recruiting

Study of Neuro-Cognitive Correlates of Pediatric Anxiety Disorders

Anxiety Disorders | Major Depressive Disorder

United States
GlaxoSmithKline

Completed

To Investigate Effects GSK561679 on Part of the Body's System That Controls the Balance of Many of the Hormones.

Depressive Disorder and Anxiety Disorders

United Kingdom
GlaxoSmithKline

Completed

First Study in Humans With GSK206136 (NSB101909)

Depressive Disorder and Anxiety Disorders

United Kingdom
GlaxoSmithKline

Completed

Emotional Processing in Healthy Volunteers in the Presence of an Investigational Anxiolytic

Depressive Disorder and Anxiety Disorders

United Kingdom
Stanford University

Recruiting

Caloric Vestibular Stimulation for Modulation of Insight in Obsessive-Compulsive Spectrum Disorders

Obsessive-Compulsive Disorder | Body Dysmorphic Disorders | Illness Anxiety Disorder

United States
Johns Hopkins University
Once Upon a Time Foundation

Completed

Electronic Communication Augmented Mental Health Care

Depressive Disorder | Anxiety Disorders | Bipolar Affective Disorder

United States
Brain and Cognition Discovery Foundation

Enrolling by invitation

Chart Review of Patients Undergoing Ketamine Infusions

Obsessive-Compulsive Disorder | Bipolar Disorder | Post Traumatic Stress Disorder | Major Depressive Disorder

Canada
VA Office of Research and Development

Recruiting

Comparing Individual Therapies for Veterans With Depression, PTSD, and Panic Disorder

Major Depressive Disorder | Posttraumatic Stress Disorder | Panic Disorder and Agoraphobia

United States
Duke University
National Institute of Mental Health (NIMH)

Completed

Antidepressant Safety in Kids Study (ASK)

Obsessive Compulsive Disorder | Anxiety Disorders | Eating Disorders | Depressive Disorders

United States

Clinical Trials on Histiocytic Disorders

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CROs in Uruguay

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Rare Diseases

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