Clinical Trials on Human Immunodeficiency Virus (HIV) Infections in Germany

Total 1108 results

Hoffmann-La Roche

Completed

A Study of the Pharmacokinetics And Pharmacodynamics of Intravenously Administered Pegasys (Peginterferon Alfa-2a) in Patients With Chronic Hepatitis C And Previous Non-Response to Pegylated Interferon And Ribavirin Combination Therapy

Hepatitis C, Chronic

Germany
Hannover Medical School

Recruiting

Improvement of Portal Hypertension During Viral Suppression in Patients With Hepatitis Delta (IMPHROVE-D) (IMPHROVE-D)

Liver Cirrhosis | Hepatitis B | Hepatitis D | Portal Hypertension

Germany
GlaxoSmithKline

Completed

Safety and Immunogenicity of 3 Lots of GSK Biologicals' HBV-MPL Vaccine and Engerix™-B in Healthy Volunteers ≥ 15y

Hepatitis B

Australia, Czech Republic, Germany, Italy, Netherlands, Switzerland, United Kingdom
Johann Wolfgang Goethe University Hospital

Unknown

Patients With Chronic Hepatitis B and Low Viremia Not Receiving Antiviral Therapy

Hepatitis B, Chronic

Germany
GlaxoSmithKline

Completed

Safety Study of Pandemic Candidate Influenza Vaccines in the Elderly Population

Influenza | Influenza Vaccines

Germany
AiCuris Anti-infective Cures AG
Medpace, Inc.

Recruiting

Trial on Efficacy and Safety of Pritelivir Tablets for Treatment of Acyclovir-resistant Mucocutaneous HSV (Herpes Simplex Virus) Infections in Immunocompromised Subjects (PRIOH-1)

HSV Infection

United States, Italy, Belgium, France, United Kingdom, Germany, Switzerland, Argentina, Australia, Georgia, Greece, Mexico, Israel, Canada
Gilead Sciences

Completed

Safety and Efficacy of SOF/VEL/VOX FDC for 12 Weeks and SOF/VEL for 12 Weeks in DAA-Experienced Adults With Chronic HCV Infection Who Have Not Received an NS5A Inhibitor (POLARIS-4)

Hepatitis C Virus Infection

United States, France, United Kingdom, Germany, Canada, Australia, New Zealand, Puerto Rico
GlaxoSmithKline

Completed

This Study Aims to Determine the Long-term Persistence of Antibodies Against Hepatitis B and to Evaluate the Immunogenicity and Safety of Hepatitis B Vaccine in Adolescents Vaccinated in Infancy With Infanrix™ Hexa

Hepatitis B

Germany
Merck Sharp & Dohme LLC

Completed

Activity of MK-8504 in Anti-retroviral-naïve, Human Immunodeficiency Virus 1 (HIV-1) Infected Participants (MK-8504-002)

HIV-1 Infection

Germany, United Kingdom
Hoffmann-La Roche

Completed

Influenza Resistance Information Study (IRIS)

Influenza

Australia, Hong Kong, United States, France, Germany, Netherlands, Norway, Poland
Merck Sharp & Dohme LLC

Completed

Safety, Tolerability, Pharmacokinetics, and Anti-Retroviral Activity of MK-8558 Monotherapy in Anti-Retroviral-Naïve HIV-1 Infected Participants (MK-8558-002)

HIV-1 Infection

Germany, Romania
ZymoGenetics
Bristol-Myers Squibb

Unknown

Efficacy and Safety Study of PEG-rIL-29 Plus Ribavirin to Treat Chronic Hepatitis C Virus Infection (EMERGE)

Hepatitis C, Chronic

Australia, France, Poland, United States, Spain, Germany, Romania, Canada, Austria, Italy, Puerto Rico
Hoffmann-La Roche
Roche Pharma AG

Completed

Influence of Ribavirin on the Initial Virological Response in Treatment Naïve Patients With Hepatitis C Genotype 1 Infection

Hepatitis C, Chronic

Germany
GlaxoSmithKline

Completed

Study to Compare the Efficacy of GSK Biologicals' Adjuvants in Combination With the Antigen of the Hepatitis B Vaccine

Hepatitis B

Germany, Belgium
GlaxoSmithKline

Completed

A Study to Evaluate Persistence of Hepatitis B Antibodies, Immunogenicity and Safety of Engerix™-B Kinder Challenge Dose, in Adolescents Vaccinated With Four Doses of Infanrix™ Hexa During Infancy

Hepatitis B

Germany
Novartis Vaccines

Completed

Safety of a Influenza Vaccine Produced Either in Mammalian Cell Culture or in Embryonated Hen Eggs in Adults and Elderly With and Without Underlying Medical Conditions, and Immunogenicity in a Subset of Subjects With Underlying Medical Conditions

Seasonal Influenza | Vaccine

Germany
Pharmasset

Completed

A Study of DPC 817 in HIV-Infected Males

HIV Infections

United States, Germany
Hannover Medical School
German Center for Infection Research

Recruiting

Terminator 2 Register

Chronic Hepatitis B, HBeAg Negative

Germany
University of Cologne

Completed

Registry for Clinical Presentation and Management of Patients With COVID-19 in the Emergency Room (ReCovER)

SARS-CoV 2 | Corona Virus Infection

Germany
Gilead Sciences

Completed

Multicenter, Randomized, Double-Blind, Double-Dummy, Phase 3 Study of the Safety and Efficacy of Elvitegravir Versus Raltegravir

HIV Infection

Canada, Germany, United States, Spain, France, Australia, Puerto Rico, Italy, Belgium, Mexico, Switzerland, Portugal, Netherlands, United Kingdom
Tibotec Pharmaceuticals, Ireland

Completed

TMC114-C214: Trial of TMC114 Administered With Low Dose Ritonavir (RTV) in HIV-1 Infected Treatment Experienced Patients

HIV Infection

United States, Australia, France, United Kingdom, Belgium, Germany, Spain, Argentina, Chile, Mexico, Portugal, Malaysia, Panama, South Africa, Canada, Netherlands, Brazil, Puerto Rico, Austria, Russian Federation, Thailand, Hungary, Denmar... and more
Universitätsklinikum Hamburg-Eppendorf
Bristol-Myers Squibb

Completed

Interferon-free Antiviral Treatment of Chronic Hepatitis C Virus Infection Among Opioid-substituted Patients (INFO)

Hepatitis C, Chronic | Opioid-Related Disorders

Germany
Arrowhead Pharmaceuticals

Terminated

Extension Study of the Safety and Efficacy of Multi-dose Intravenous ARC-520 in Patients With Chronic Hepatitis B (HBV) Infection

Hepatitis B

Korea, Republic of, Germany, China
Technical University of Munich
Charite University, Berlin, Germany

Recruiting

Chronic Fatigue Syndrome/ Myalgic Encephalomyelitis (ME/CFS) Registry and Biobank, COVID-19, SARS-CoV-2 (MECFS-R)

Fatigue Syndrome, Chronic | SARS CoV 2 Infection | ME/CFS | Epstein-Barr Virus

Germany
Glaxo Wellcome

Completed

A Study of the Safety and Effectiveness of Different Doses of 1592U89 in HIV-Infected Patients

HIV Infections

France, Germany
Innovative Molecules GmbH

Recruiting

Phase I Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of Single Doses of IM-250 in Healthy Volunteers

Herpes Simplex Virus

Germany
GlaxoSmithKline

Completed

Study to Evaluate an Influenza Vaccine Candidate

Influenza

France, Spain, Germany
ViiV Healthcare
Pfizer

Completed

Pharmacokinetics, Pharmacodynamics, And Safety Of Maraviroc (UK-427,857) In Patients With Human Immunodeficiency Virus

HIV Infections

Netherlands, Germany, United Kingdom
Immune System Regulation AB

Unknown

Efficacy and Safety of GnRH Analogue Triptorelin for HIV-1 Reservoir Reduction in ART Treated HIV-1 Infected Patients

HIV-1-infection

Sweden, Germany
FGK Clinical Research GmbH
University Hospital, Saarland

Completed

Individually Adapted Therapy Duration for the Treatment of Chronic Hepatitis C Genotype 1 Infection

Hepatitis C, Chronic

Germany
GlaxoSmithKline

Completed

Hepatitis B Antibody Persistence and Immune Response to Hepatitis B Vaccine Challenge in Previously Vaccinated Children

Hepatitis B

Germany
Janssen R&D Ireland

Completed

3-year Follow-up Study in Patients Previously Treated With TMC435-Containing Regimen for the Treatment of Hepatitis C Virus Infection

Hepatitis C

United States, Canada, France, Belgium, Germany, Russian Federation, Poland
Radboud University Medical Center

Terminated

Pharmacokinetics of Atazanavir /Dolutegravir/Lamivudine Regimen as Maintenance Regimen (PRADAII)

HIV-1 Infection

Netherlands, Germany
Tibotec Pharmaceuticals, Ireland

Completed

A Study to Assess the Anti-viral Activity, Safety, Tolerability and Pharmacokinetics of TMC435350 in Participants Infected With Hepatitis C-Virus (HCV)

Hepatitis C

Belgium, Germany, Thailand
Hoffmann-La Roche

Completed

A Pharmacokinetic/Pharmacodynamic (PK/PD) and Safety Evaluation of Oseltamivir [Tamiflu] in the Treatment of Infants 0 to <12 Months of Age With Confirmed Flu Infection

Influenza

Belgium, Poland, France, Germany, Italy, Spain
University of Erlangen-Nürnberg Medical School

Recruiting

Low-field Magnetic Resonance Imaging in Pediatric Post Covid-19 (FASCINATE)

COVID-19 | Long COVID | COVID-19 Respiratory Infection

Germany
GlaxoSmithKline

Completed

Evaluation of the Long-term Persistence of Immunity to Hepatitis B, in Adolescents Vaccinated in Infancy With Engerix™-B Kinder

Hepatitis B

Germany
Valneva Austria GmbH

Completed

Virological Response Study of the HCV Vaccine IC41

Chronic Hepatitis C

Germany, Poland, Romania
Sanofi Pasteur, a Sanofi Company

Completed

Safety Surveillance of VaxigripTetra® and Efluelda® Influenza Vaccines in Europe During the Influenza Season 2022/23

Influenza (Healthy Volunteers)

Germany, Finland
Janssen R&D Ireland

Completed

A Study of Pharmacokinetics, Efficacy, Safety, Tolerability, of the Combination of Simeprevir (TMC435), Daclatasvir (BMS-790052), and Ribavirin (RBV) in Patients With Recurrent Chronic Hepatitis C Genotype 1b Infection After Orthotopic Liver Transplantation

Hepatitis C, Chronic

Spain, Germany, Poland
ANRS, Emerging Infectious Diseases
EUCLID Clinical Trial Platform

Recruiting

ANRS HB07 IP-Cure-B Proof of Concept (PoC) Clinical Trial. Educating the Liver Immune Environment Through TLR8 Stimulation Followed by NUC Discontinuation (IP-CURE-B)

Hepatitis B, Chronic

France, Germany, Italy, Spain
GlaxoSmithKline

Completed

Safety & Immunogenicity of an Alternative Immunization Schedule of GSK Bio's Pandemic Influenza Vaccine (GSK1119711A)

Influenza | Influenza Vaccines

Germany
Janssen-Cilag International NV

Completed

A Study of TMC435 Plus Pegylated Interferon Alfa-2a and Ribavirin in Participants With Chronic HCV Infection

Hepatitis C, Chronic | Infection

United Kingdom, Germany, Spain, Belgium, Saudi Arabia, Austria, France
PENTA Foundation

Completed

PENTA15: Pharmacokinetic Study of Once Versus Twice Daily Abacavir in HIV-1 Infected Children Aged 3 to <36 Months (PENTA15)

HIV Infection

France, Germany, Italy, Spain, United Kingdom
Novartis Pharmaceuticals

Completed

Pharmacokinetics and Safety of Single-Dose Telbivudine in Children and Adolescents With Chronic Hepatitis B

Chronic Hepatitis B

Belgium, Germany, United Kingdom, Philippines
University Hospital Tuebingen

Unknown

Prospective Registry of Corona Virus Disease 2019 (Covid-19) Patients With Neuromuscular Involvement

Myocarditis | COVID | Myositis | Corona Virus Infection | Sars-CoV2

Germany
Medicago

Completed

Efficacy, Safety, and Immunogenicity of a Plant-Derived Quadrivalent Virus-Like Particles (VLPs) Influenza Vaccine in Adults

RNA Virus Infections | Virus Diseases | Respiratory Tract Infections | Respiratory Tract Diseases | Influenza

United States, Canada, Finland, Germany, Philippines, Thailand, United Kingdom
Hegau-Bodensee-Klinikum Singen

Completed

Fatigue a Long COVID-19 Symptom Substudy of FSC19-KN Trial (SubFSC19-KN)

SARS-CoV2 Infection

Germany
Themis Bioscience GmbH

Completed

Phase II Study to Evaluate Safety and Immunogenicity of a Chikungunya Vaccine (MV-CHIK-202)

Chikungunya Virus Infection

Austria, Germany
Hannover Medical School
Gilead Sciences; HepNet Study House, German Liverfoundation; German Center for...

Completed

Trial for the Treatment of Acute Hepatitis C for 8 Weeks With Sofosbuvir/Velpatasvir

Hepatitis C | Acute Hepatitis C

Germany

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