Clinical Trials on Human Papillomavirus (HPV)-Positive Oropharyngeal Cancer

Total 351 results

Lisette Nixon
Stanford University; University of Leipzig; AdventHealth; UNICANCER; Princess Alexandra...

Recruiting

Post-operative Adjuvant Treatment for HPV-positive Tumours (PATHOS) (PATHOS)

Human Papillomavirus (HPV)-Positive Oropharyngeal Cancer

Germany, United Kingdom, United States, Australia, France
Rutgers, The State University of New Jersey
National Cancer Institute (NCI)

Active, not recruiting

Swallowing Outcomes and Circulating Tumor DNA in Patients With HPV Related Oropharyngeal Cancer Treated With Transoral Surgery and Reduced Intensity Adjuvant Therapy

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Oropharyngeal Human Papillomavirus-Positive Squamous...

United States
Mayo Clinic

Recruiting

Blood-Based Biomarkers to Inform Treatment and Radiation Therapy Decisions for HPV Associated Oropharyngeal Squamous Cell Head and Neck Cancers

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Oropharyngeal Human Papillomavirus-Positive Squamous...

United States
Jonsson Comprehensive Cancer Center
AstraZeneca

Terminated

Stereotactic Body Radiation Therapy and Durvalumab With or Without Tremelimumab Before Surgery in Treating Participants With Human Papillomavirus Positive Oropharyngeal Squamous Cell Caner

Oropharyngeal Squamous Cell Carcinoma | Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Pathologic... and other conditions

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Immunologic Responses in HPV-Associated Carcinoma for Patients Receiving Chemoradiation

Head and Neck Cancer | HPV (Human Papillomavirus)-Associated Carcinoma | Oropharyngeal

United States
Mayo Clinic

Recruiting

Prospective Assessment of HPV Associated Anogenital Pathology in Female Patients and Female Partners of Patients With Confirmed HPV Associated Oropharyngeal Carcinoma, PAP-OP Study

Oropharyngeal Human Papillomavirus-Positive Squamous Cell Carcinoma

United States
Gilead Sciences

Terminated

Study to Evaluate the Safety and Efficacy of KITE-439 in HLA-A*02:01+ Adults With Relapsed/Refractory HPV16+ Cancers

Human Papillomavirus (HPV) 16+ Relapsed/Refractory Cancer

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Ipilimumab, Nivolumab, and Radiation Therapy in Treating Patients With HPV Positive Advanced Oropharyngeal Squamous Cell Carcinoma

Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7 | Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma... and other conditions

United States
The University of Texas Health Science Center,...
Baylor College of Medicine; Cancer Prevention Research Institute of Texas

Completed

Multi-component Interventions to Increase HPV Vaccination in a Network of Pediatric Clinics

Human Papillomavirus (HPV)

United States
Ann & Robert H Lurie Children's Hospital of Chicago

Unknown

Utilization of Human Papillomavirus (HPV) Vaccine Among Young Men Who Have Sex With Men (MSM) and Parents of Boys (Aged 9 to 18 Years)

Human Papillomavirus (HPV)

United States
Jonathan Schoenfeld, MD, MPH
Naveris

Recruiting

Risk-adapted Therapy in HPV+ Oropharyngeal Cancer Using Circulating Tumor (ct)HPV DNA Profile - The ReACT Study

HPV Positive Oropharyngeal Squamous Cell Carcinoma | Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC... and other conditions

United States
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Active, not recruiting

HPV-16/18 E6/E7-Specific T Lymphocytes, Relapsed HPV-Associated Cancers, HESTIA (HESTIA)

Human Papillomavirus-Related Carcinoma | Human Papillomavirus Positive Oropharyngeal Carcinoma | Human Papillomavirus Positive Cervical Carcinoma | Human Papillomavirus Positive Anal Carcinoma | Human Papillomavirus Positive Vulvar Carcinoma | Human Papillomavirus Positive Penile Carcinoma

United States
National Institute for Control of Vaccine and Biologicals

Unknown

Safety Study of GlaxoSmithKline (GSK) Biologicals' Human Papillomavirus (HPV) Vaccine in Healthy Vietnamese Women According to a 0, 1, 6 Month Schedule (HPV-022 PRI)

Human Papillomavirus (HPV) Vaccine

Vietnam
University of Florida
Patient-Centered Outcomes Research Institute; National Cancer Institute (NCI)

Not yet recruiting

Maximizing HPV Vaccination: Real-time Reminders, Guidance, and Recommendations - Part 4: Feasibility Trial

Human Papillomavirus (HPV) Vaccines

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Study of Mucosal Sparing Adjuvant Radiotherapy After Surgical Exploration in HPV+ Head and Neck Cancer of Unknown Primaries

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Pathologic Stage I HPV-Mediated (p16-Positive)... and other conditions

United States
University of Pittsburgh
Merck Sharp & Dohme LLC

Completed

Randomized Trial of Alternative HPV Vaccination Schedules in Males in a University Setting

Quadrivalent HPV Vaccine | Human Papillomavirus Vaccine

United States
Mayo Clinic

Recruiting

A Vaccine (PDS0101) Alone or in Combination With Pembrolizumab for the Treatment of Locally Advanced Human Papillomavirus-Associated Oropharynx Cancer

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Stage IVB Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Human Papillomavirus-Related Carcinoma | Locally Advanced Oropharyngeal Carcinoma

United States
Klein Buendel, Inc.
National Cancer Institute (NCI); Indiana University; University of New Mexico

Completed

Web App Technology for Boys and Parents: Improving HPV Vaccine Uptake

HPV | Human Papillomavirus Virus

United States
Emory University
National Cancer Institute (NCI)

Recruiting

Biomarker-Driven Radiation Therapy Dose Reduction After Transoral Robotic Surgery for the Treatment of HPV-Positive Oropharyngeal Cancer

Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Oropharyngeal HPV-Positive Squamous Cell Carcinoma

United States
National Cancer Institute (NCI)

Recruiting

Testing Immunotherapy Versus Observation in Patients With HPV Throat Cancer

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Pathologic Stage III HPV-Mediated (p16-Positive)...

United States
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins University; Dana-Farber Cancer Institute; Icahn School of Medicine... and other collaborators

Completed

Human Papillomavirus (HPV) Oral Transmission Study in Partners Over Time (HOTSPOT)

Oropharyngeal Cancer | Human Papillomavirus

United States
Memorial Sloan Kettering Cancer Center

Completed

Ribavirin for Patients With Recurrent/Metastatic (R/M) Human Papillomavirus (HPV)-Related Malignancies

Human Papillomavirus (HPV)-Related Malignancies | Recurrent/Metastatic (R/M) Human Papillomavirus (HPV)-Related Malignancies

United States
University of Edinburgh

Recruiting

The Role of Circulating Tumour DNA in Head and Neck Cancer

Oropharyngeal Squamous Cell Carcinoma | Human Papillomavirus (HPV)

United Kingdom
Vanderbilt University Medical Center
American Cancer Society, Inc.

Completed

New Modalities for Detection of Oropharyngeal Cancer

Oropharynx Cancer | Tonsil Cancer | Human Papillomavirus Positive Oropharyngeal Squamous Cell Carcinoma | Base of Tongue Carcinoma

United States
University of Chicago

Recruiting

TheraT® Vectors (Vaccines) Combined With Chemotherapy to Treat HPV16 Head and Neck Cancers

Head and Neck Cancer | HPV Positive Oropharyngeal Squamous Cell Carcinoma | HPV | Human Papilloma Virus

United States
National Taiwan University Hospital

Unknown

102 Annual Pap Smear Screening Database Maintenance Project

Cancer | Human Papillomavirus

Taiwan
Assistance Publique - Hôpitaux de Paris

Completed

Molecular Signatures of HPV+ ORL Cancers (OROPAP) (OROPAP)

Oropharyngeal Cancer | Human Papillomavirus-Related Carcinoma

France
Ohio State University Comprehensive Cancer Center
National Cancer Institute (NCI)

Withdrawn

Digital PET Scan for the Prediction of Outcomes in Patients With Locally Advanced Oropharyngeal Cancer

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Pathologic Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma... and other conditions

United States
University of Texas Southwestern Medical Center
Gateway for Cancer Research

Active, not recruiting

HYHOPE: De-intensified Hypofractionated Radiation Therapy for HPV-associated Oropharynx Cancer

Oropharyngeal Cancer | Human Papillomavirus-Related Carcinoma

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI); The Emmes Company, LLC; Inovio Pharmaceuticals

Active, not recruiting

VGX-3100 and Electroporation in Treating Patients With HIV-Positive High-Grade Anal Lesions

Anal Intraepithelial Neoplasia | High Grade Squamous Intraepithelial Neoplasia | HIV Positivity | Human Papillomavirus-16 Positive | Human Papillomavirus-18 Positive

United States, Puerto Rico
M.D. Anderson Cancer Center

Completed

Sexual Behavior in Oropharyngeal Patients Versus Head and Neck Cancer Patients, With or Without HPV Infection

Head and Neck Cancer | Oropharyngeal Cancer | Human Papillomavirus Infection

United States
Jonsson Comprehensive Cancer Center
Eli Lilly and Company

Terminated

Radiation Therapy and Cisplatin With or Without Cetuximab in Treating Patients With HPV Positive, KRAS-Variant Stage III-IV Oropharyngeal Squamous Cell Carcinoma

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Pathologic Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Pathologic Stage IV HPV-Mediated (p16-Positive)... and other conditions

United States
Merck Sharp & Dohme LLC

Completed

GARDASIL Reexamination Study (V501-059)

Human Papillomavirus (HPV) Infection
GlaxoSmithKline

Completed

Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' Human Papillomavirus (HPV) Vaccine (GSK580299) in Healthy Female Subjects 10-25 Years of Age.

Human Papillomavirus (HPV) Infection

Senegal, Tanzania
Paul W. Read, MD

Terminated

OPSCC N0 Nodal Control With Reduced IMRT

Oropharyngeal Squamous Cell Carcinoma (OPSCCA) | HPV (Human Papillomavirus)-Associated

United States
National Cancer Institute (NCI)
NRG Oncology

Suspended

De-intensified Radiation Therapy With Chemotherapy (Cisplatin) or Immunotherapy (Nivolumab) in Treating Patients With Early-Stage, HPV-Positive, Non-Smoking Associated Oropharyngeal Cancer

Oropharyngeal Squamous Cell Carcinoma | Squamous Cell Carcinoma | Basaloid Squamous Cell Carcinoma | Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Papillary Squamous Cell Carcinoma | Pathologic Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC... and other conditions

United States, Canada
Inovio Pharmaceuticals

Completed

Fourth Dose of Human Papillomavirus (HPV) DNA Plasmid (VGX-3100) + EP in Adult Females Previously Vaccinated With Three Doses of VGX-3100

Human Papillomavirus (HPV)

Puerto Rico, United States
The Alfred
Merck Sharp & Dohme LLC

Completed

Prevalence of Genital HPV Infection in Males Following Introduction of Universal Male HPV Vaccination (Impress)

Human Papillomavirus

Australia
University of Aarhus
Aarhus University Hospital

Completed

Immune Response to Bivalent and Tetravalent Human Papillomavirus Vaccine in HIV Infected Adults (HIPAVAC)

HIV | Human Papillomavirus

Denmark
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Blood Tests and Questionnaires in Studying Adherence to Preventative Swallowing Exercises in Participants With Metastatic Head and Neck Cancer

Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Stage IV Hypopharyngeal Carcinoma AJCC v8 | Stage IV Laryngeal Cancer... and other conditions

United States
TScan Therapeutics, Inc.

Recruiting

A Basket Study of Customized Autologous TCR-T Cell Therapies in Patients With Locally Advanced (Unresectable) or Metastatic Solid Tumors

Melanoma | Cervical Cancer | Head and Neck Cancer | HPV-Related Malignancy | Ovarian Cancer | HPV-Related Carcinoma | HPV-Related Cervical Carcinoma | HPV Positive Oropharyngeal Squamous Cell Carcinoma | Non-small Cell Carcinoma | HPV - Anogenital Human Papilloma Virus Infection | HPV-Related Adenocarcinoma | HPV-Related Adenosquamous Carcinoma and other conditions

United States
Monash University
The Alfred; University of Melbourne

Recruiting

Human Papillomavirus in Young People Epidemiological Research 3 (HYPER3)

Cancer | Anal Cancer | HPV Infection | HPV | Human Papillomavirus Infection | Men | HPV 16 Infection

Australia
Ohio State University Comprehensive Cancer Center

Recruiting

Adaptive De-intensified Radiotherapy Using Circulating Tumor DNA in HPV- Associated Oropharyngeal Cancer

Oropharyngeal Squamous Cell Carcinoma | Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8

United States
Centre Hospitalier Universitaire de Saint Etienne
Ministry of Health, France

Completed

Prevalence of HPV Transmission During Medically Assisted Procreation Procedures (AMPAMAVIR)

Infertility | Human Papillomavirus (HPV) | Medically Assisted Procreation (MAP)

France
Monash University
The Alfred; University of Melbourne

Recruiting

Human Papillomavirus in Young People Epidemiological Research 4 (HYPER4)

Cancer | Anal Cancer | HPV Infection | HPV | Human Papillomavirus Infection | Men | HPV 16 Infection

Australia
Memorial Sloan Kettering Cancer Center

Recruiting

A Study Using Human Papillomavirus (HPV) DNA Testing to Detect HPV-Related Oropharyngeal Cancer (OPC)

Oropharyngeal Cancer | HPV-Related Carcinoma | HPV Positive Oropharyngeal Squamous Cell Carcinoma

United States
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of Reduced Radiation Therapy and Standard-of-Care Chemotherapy in People With HPV-Positive Throat Cancer

Oropharyngeal Cancer | HPV | Human Papilloma Virus | Throat Cancer | Oropharyngeal Carcinoma

United States
Regina Elena Cancer Institute
University of California, San Diego; Lega Italiana per la Lotta contro i Tumori

Recruiting

New Prognostic and Predictive Biomarkers for HPV-associated Oropharyngeal Cancer

PREDICTIVE BIOMARKERS | Evaluation of HPV-specific E5 Transcript Expression in a Cohort of Patients With HPV-associated OPC | HPV 16 Positive Oropharyngeal Tumors (OPC)

Italy
The Behavioural Insights Team
UNICEF; National Center for Disease Control and Public Health, Georgia; Information...

Not yet recruiting

SMS Reminders to Strengthen Demand for HPV Vaccination in Georgia

HPV, Human Papillomavirus Viruses, Human Papilloma Virus Vaccine
Hyunseok Kang, MD
NRG Oncology

Completed

Sodium Thiosulfate in Preventing Ototoxicity for Squamous Cell Cancer Patients Undergoing Chemoradiation With Cisplatin

Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Lip and Oral Cavity Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Stage IV Hypopharyngeal... and other conditions

United States

Clinical Trials on Human Papillomavirus (HPV)-Positive Oropharyngeal Cancer

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