Clinical Trials on Hydroxychloroquine Toxicity in Canada

Total 48 results

Dr. S.S. Michel Clinic

Completed

Monitoring and Preventing Hydroxychloroquine, Plaquenil, Toxicity.

Hydroxychloroquine Toxicity

Canada
University of Toronto

Completed

Pulmonary Function After Hyperbaric Oxygen Therapy

Oxygen Toxicity

Canada
University of British Columbia
Boehringer Ingelheim; Abbott; CIHR Canadian HIV Trials Network

Completed

NRTI-Sparing Pilot Study

HIV | Mitochondrial Toxicity

Canada
Takeda

Completed

Case Control Study of Pharmacogenomic Factors Associated With Hepatocellular Injury Following Exposure to Lapaquistat Acetate

Toxicity

United States, Argentina, Poland, South Africa, Russian Federation, Netherlands, Chile, Canada, Germany, Latvia, Finland, United Kingdom, Czech Republic, Slovakia
Laval University

Recruiting

Comparison of Two Oxygenation Targets With Two Different Oximeters - Impact on Oxygen Flow Rates and Oxygenation (Oxygap pong)

Respiratory Failure | Oxygen Toxicity

Canada
Mansoura University

Unknown

Development and Validation of "Ready-to-Use" Inhalable Forms of Hydroxychloroquine for Treatment of COVID-19

Covid19 | Hydroxychloroquine Adverse Reaction

Egypt
Evelyne Vinet
McGill University Health Centre/Research Institute of the McGill University... and other collaborators

Recruiting

At the Heart of the Matter - Speckle Tracking Echocardiography in Lupus Mothers and Their Offspring

Cardiovascular Diseases | Systemic Lupus Erythematosus | Pregnancy Complications | Cardiovascular Morbidity | Hydroxychloroquine | Cardiovascular Complication | Placenta-mediated Pregnancy Complications | Speckle Tracking Echocardiography

Canada
Julie Lemieux

Recruiting

App for Adverse Events to Oral Chemotherapy - Pilot Study

Breast Neoplasms | Chemotherapeutic Toxicity

Canada
Laval University

Unknown

Closed-Loop Oxygen to Verify That Healthcare Workers Interventions Decrease During SARS-CoV-2 Pneumonia (COVID-19)

Pneumonia | Coronavirus | Oxygen Toxicity

Canada
Sunnybrook Health Sciences Centre
Queen's University; The Leukemia and Lymphoma Society

Recruiting

Clonal Hematopoiesis is a Risk Factor for Chemotherapy-Related Complications

Lymphoma | Chemotherapeutic Toxicity

Canada
François Lellouche

Unknown

Influence of FreeO2 on Percentage of Time Within Oxygen Saturation Target Using Noninvasive Ventilation (NIV) and Continuous Positive Airway Pressure (CPAP) for Patients Admitted for AECOPD or Bariatric Surgery

Surgery | COPD Exacerbation | Abdominal Obesity | Oxygen Toxicity

Canada
British Columbia Cancer Agency
Princess Margaret Hospital, Canada; London Regional Cancer Program, Canada; Tom...

Not yet recruiting

Single vs. Multiple Fraction Trial of Stereotactic Ablative Radiotherapy for Comprehensive Treatment of Oligometastases/Progression

Quality of Life | Toxicity Due to Radiotherapy | Oligometastatic Disease | Oligoprogression

Canada
McMaster University
St. Joseph's Healthcare Hamilton; Juravinski Cancer Center

Recruiting

Financial Toxicity in Breast Cancer Surgery

Breast Cancer

Canada
University Health Network, Toronto
University College London Hospitals; Brigham and Women's Hospital; University... and other collaborators

Recruiting

The STOP-MED CTRCD Trial (STOP-MED)

Heart Failure | Cancer | Cardiotoxicity | Cardiac Toxicity | Antineoplastics Toxicity

Canada, United States, United Kingdom, Australia
McGill University Health Centre/Research Institute...

Enrolling by invitation

Stereotactic Arrhythmia Radioablation for Ventricular Tachycardia (StAR-VT) (StAR-VT)

Arrhythmia | Ventricular Tachycardia | Radiation Toxicity | Arrhythmic Storm

Canada
Lawson Health Research Institute
Canadian Institutes of Health Research (CIHR)

Unknown

Detecting Radiation-Induced Cardiac Toxicity After Non-Small Cell Lung Cancer Radiotherapy (RICT-LUNG)

Non-small Cell Lung Cancer | Radiation Toxicity

Canada
Lawson Health Research Institute

Unknown

Hybrid PET/MR Imaging of Acute Cardiac Inflammation After Left-Sided Breast Cancer Radiotherapy (RICT-BREAST)

Radiation Toxicity | Left-Sided Breast Cancer

Canada
Dana-Farber Cancer Institute
National Cancer Institute (NCI)

Completed

Treatment of Acute Lymphoblastic Leukemia in Children

Leukemia | Drug/Agent Toxicity by Tissue/Organ

United States, Canada
Laval University

Recruiting

Automated Adjustment of Oxygen on Patient With Acute COPD Exacerbation - FreeO2 HypHop (FreeO2 HypHop)

COPD Exacerbation | Hypoxemia | Hyperoxia | Oxygen Toxicity | Hypoxic Respiratory Failure

Canada
University of Alberta

Completed

IMPACT: IMPact of Antimalarials on Covid-19 Infections in RAPPORT (IMPACT)

Rheumatoid Arthritis | Psoriatic Arthritis | Covid-19 Infection | Hydroxychloroquine

Canada
Herbert Irving Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Silymarin (Milk Thistle Extract) in Treating Patients With Acute Lymphoblastic Leukemia Who Are Receiving Chemotherapy

Leukemia | Drug/Agent Toxicity by Tissue/Organ

United States, Canada
AHS Cancer Control Alberta

Terminated

Novel Surrogate Markers as Predictors of Radiation Toxicity in Breast Cancer Patients Undergoing Helical Tomotherapy Compared to Standard Radiation Therapy

Cardiac Toxicity | Genetic Markers | Breast and Skin Motion

Canada
Nova Scotia Health Authority

Completed

Exercise to Prevent AnthrCycline-based Cardio-Toxicity Study (EXACT)

Neoplasms | Inflammation | Heart; Disease, Functional

Canada
Fundación Centro Nacional de Investigaciones Cardiovasculares...
European Commission

Recruiting

REmote iSchemic condItioning in Lymphoma PatIents REceiving ANthraCyclinEs (RESILIENCE)

Lymphoma | Anthracycline-induced Cardiac Toxicity

Netherlands, Spain, Denmark, Germany, France, Portugal
Nova Scotia Health Authority
Canadian Institutes of Health Research (CIHR); Canadian Cancer Society (CCS)

Recruiting

Exercise to Prevent AnthraCycline-based Cardio-Toxicity Study 2.0 (EXACT2) (EXACT 2)

Cardiovascular Diseases | Cardiotoxicity | Cancer, Breast

Canada
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Amifostine in Treating Patients With Stage II or Stage III Non-small Cell Lung Cancer

Lung Cancer | Radiation Toxicity | Oral Complications | Drug/Agent Toxicity by Tissue/Organ

United States, Canada
Fundacion CRIS de Investigación para Vencer el...
Apices Soluciones S.L.; Amgen

Completed

Skin Toxicity in Patients With Metastatic Colorectal Cancer Treated With Anti-EGFR and Chemotherapy (DERMIA) (DERMIA)

Skin Toxicity

Spain
Wellstat Therapeutics

Completed

Triacetyluridine and Fluorouracil Compared With Gemcitabine in Treating Patients With Unresectable Locally Advanced, or Metastatic Pancreatic Cancer

Pancreatic Cancer | Drug/Agent Toxicity by Tissue/Organ

United States, Canada
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Standard Versus Intensity-Modulated Pelvic Radiation Therapy in Treating Patients With Endometrial or Cervical Cancer

Cervical Cancer | Endometrial Cancer | Radiation Toxicity | Perioperative/Postoperative Complications | Gastrointestinal Complications | Urinary Complications | Urinary Tract Toxicity

United States, Canada, Singapore, Hong Kong
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Salivary Gland Surgery Before Radiation Therapy in Preventing Radiation-Caused Xerostomia in Patients With Head and Neck Cancer

Head and Neck Cancer | Xerostomia | Radiation Toxicity

United States, Canada
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Radiation Therapy in Treating Patients With Stage II or Stage III Oropharyngeal Cancer

Head and Neck Cancer | Radiation Toxicity

United States, Canada
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Radiation Therapy in Treating Patients With Prostate Cancer

Sexual Dysfunction | Prostate Cancer | Radiation Toxicity | Psychosocial Effects of Cancer and Its Treatment

United States, Canada
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Amifostine in Treating Children With Malignant Germ Cell Tumors

Ovarian Cancer | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor | Drug/Agent Toxicity by Tissue/Organ

United States, Canada, Netherlands, Puerto Rico, Switzerland, Australia
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Evaluation of Memory Skills in Patients Receiving Radiation Therapy for Brain Metastases

Metastatic Cancer | Radiation Toxicity | Cognitive/Functional Effects

United States, Canada
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Enalapril in Treating Heart Damage Patients Who Received Anthracycline Chemotherapy for Childhood Cancer

Unspecified Childhood Solid Tumor, Protocol Specific | Cardiac Toxicity

United States, Canada, Switzerland
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology

Completed

Image-Guided Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Shoulder, Arm, Hip, or Leg

Sarcoma | Lymphedema | Radiation Toxicity | Radiation Fibrosis | Musculoskeletal Complications

United States, Canada
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Melatonin and Radiation Therapy in Treating Patients With Brain Metastases

Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer | Radiation Toxicity

United States, Canada
University of Calgary
The Hospital for Sick Children; CHU de Quebec-Universite Laval; McMaster University and other collaborators

Recruiting

HRQL and Symptom Assessment for Patients With DIPG or Recurrent and Re-irradiated Brain Tumours and Their Caregivers

Radiation Toxicity | Radiation Exposure | DIPG | Brain Tumor, Pediatric, Recurrent | Brain Tumor, Pediatric | Brain Tumor, DIPG

Canada
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Completed

Sargramostim in Decreasing Mucositis in Patients Receiving Radiation Therapy for Head and Neck Cancer

Head and Neck Cancer | Radiation Toxicity | Oral Complications

United States, Canada
Radiation Therapy Oncology Group
National Cancer Institute (NCI); NRG Oncology; Cancer and Leukemia Group B; North...

Completed

High-Dose or Standard-Dose Radiation Therapy and Chemotherapy With or Without Cetuximab in Treating Patients With Newly Diagnosed Stage III Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery

Lung Cancer | Radiation Toxicity

United States, Canada
Radiation Therapy Oncology Group
National Cancer Institute (NCI)

Terminated

Palifermin in Lessening Oral Mucositis in Patients Undergoing Radiation Therapy and Chemotherapy for Locally Advanced Head and Neck Cancer

Pain | Head and Neck Cancer | Mucositis | Radiation Toxicity

United States, Canada
Children's Oncology Group
National Cancer Institute (NCI); Children's Cancer Group

Completed

Chemotherapy Followed by Radiation Therapy in Treating Young Patients With Newly Diagnosed Hodgkin's Disease

Lymphoma | Cardiac Toxicity

United States, Australia, Canada
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Dexrazoxane in Treating Children With Hodgkin's Disease

Lymphoma | Cardiac Toxicity

United States, Canada, Switzerland
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Rituximab, Bendamustine Hydrochloride, and Bortezomib Followed by Rituximab and Lenalidomide in Treating Older Patients With Previously Untreated Mantle Cell Lymphoma

Lymphoma | Neurotoxicity | Therapy-related Toxicity

United States, Canada
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Dexrazoxane in Treating Patients With Newly Diagnosed Nonmetastatic Osteosarcoma

Sarcoma | Cardiac Toxicity

United States, Canada, Netherlands, Puerto Rico, Switzerland, Australia
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Epoetin Alfa in Treating Anemia in Patients Who Are Receiving Chemotherapy

Lymphoma | Leukemia | Breast Cancer | Chronic Myeloproliferative Disorders | Anemia | Small Intestine Cancer | Lung Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Drug/Agent Toxicity by Tissue/Organ

United States, Canada
ImmunoGen, Inc.

Not yet recruiting

A Study of Ocular Toxicity Evaluation and Mitigation During Treatment With Mirvetuximab Soravtansine in Participants With Recurrent Ovarian Cancer With High Folate Receptor-Alpha Expression

Recurrent Ovarian Cancer | Folate Receptor-Alpha Positive

United States, Spain, Australia, Belgium, Canada, France, Ireland, Italy
UMC Utrecht
M.D. Anderson Cancer Center; Odense University Hospital; Radboud University Medical... and other collaborators

Recruiting

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study (MOMENTUM)

Neoplasms | Quality of Life | Breast Cancer | Head and Neck Cancer | Head and Neck Neoplasms | Gynecologic Cancer | Liver Neoplasms | Pancreatic Neoplasms | Pancreatic Cancer | Esophageal Cancer | Lung Cancer | Rectal Cancer | Rectal Neoplasms | Prostate Cancer | Brain Cancer | Brain Tumor | Bladder Cancer | Liver Metastases | T... and other conditions

United States, Netherlands, Germany, Canada, Denmark, United Kingdom, Australia, Belgium, Italy

Clinical Trials on Hydroxychloroquine Toxicity in Canada

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Uganda

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations