Clinical Trials on Hypertrophy in United Kingdom

Total 299 results

University of Exeter

Completed

Supplemental Protein And Resistance Training Adaptations (SPARTA)

Hypertrophy

United Kingdom
Bristol-Myers Squibb

Recruiting

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive HCM) (DISCOVER-HCM)

Obstructive Hypertrophic Cardiomyopathy

United States, Puerto Rico
Bristol-Myers Squibb

Active, not recruiting

A Study to Evaluate Mavacamten in Adults With Symptomatic Obstructive HCM Who Are Eligible for Septal Reduction Therapy (VALOR-HCM)

HOCM, Hypertrophic Obstructive Cardiomyopathy

United States
Children's Healthcare of Atlanta

Terminated

Hypertrophic Myopathy in Children

Congenital Disorders

United States
University of Exeter
Quorn

Active, not recruiting

Mycoprotein, Resistance Training, and Hypertrophy (HAM)

Hypertrophy

United Kingdom
Cytokinetics

Recruiting

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic nHCM (ACACIA-HCM)

Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cyclosporine A to Treat Hypertrophic Cardiomyopathy (HCM)

Cardiomyopathy, Hypertrophic | Heart Hypertrophy

United States
Duke University
Gilead Sciences

Completed

Ranolazine for the Treatment of Chest Pain in HCM Patients (RHYME)

Hypertrophic Cardiomyopathy

United States
Tenaya Therapeutics

Recruiting

Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM (MyPEAK-1)

Hypertrophic Cardiomyopathy

United States
AVAVA, Inc.

Recruiting

The MIRIA Acne Scar Study (MIRIA)

Acne Scars - Mixed Atrophic and Hypertrophic

United States
MyoKardia, Inc.

Completed

A Phase 2 Open-label Pilot Study Evaluating MYK-461 in Subjects With Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract Obstruction (PIONEER-HCM)

Cardiomyopathy, Hypertrophic Obstructive | Left Ventricular Outflow Tract Obstruction

United States
University of Dundee

Completed

MetfoRmin and Its Effects on Left Ventricular Hypertrophy in Normotensive Patients With Coronary Artery Disease (MET-REMODEL)

Coronary Artery Disease | Insulin Resistance | PreDiabetes | Left Ventricular Hypertrophy

United Kingdom
Bristol-Myers Squibb

Recruiting

A Study to Evaluate Mavacamten in Adolescents With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Cardiomyopathy, Hypertrophic

United States, Australia, Canada, France, Germany, Ireland, Italy, Spain, United Kingdom
Massachusetts General Hospital
National Heart, Lung, and Blood Institute (NHLBI); Brigham and Women's Hospital

Active, not recruiting

The Impact of Exercise-Induced Cardiac Remodeling on Myocardial Efficiency

Cardiomyopathy, Hypertrophic

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Long-Term Results of DDD Pacing in Obstructive Hypertrophic Cardiomyopathy

Cardiomyopathy, Hypertrophic

United States
Stanford University
University of Michigan

Unknown

Exercise Study Including Patients With Hypertrophic Cardiomyopathy

Cardiomyopathy, Hypertrophic

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

The Role of Heart Stiff and Weak Atrium on Exercise Capacity in Patients With Hypertrophic Cardiomyopathy

Cardiomyopathy, Hypertrophic

United States
Imperial College London

Completed

Regeneration of Liver: Portal Vein Embolization Versus Radiofrequency Assisted Ligation for Liver Hypertrophy (REBIRTH) (REBIRTH)

Cancer | Liver Resection

United Kingdom
University of Michigan
Stanford University

Completed

Study of Exercise Training in Hypertrophic Cardiomyopathy (RESET-HCM)

Cardiomyopathy, Hypertrophic

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Study of Blood Flow in Heart Muscle

Myocardial Ischemia | Coronary Disease | Healthy | Hypertrophic Cardiomyopathy

United States
Gilead Sciences

Terminated

Effect of Eleclazine (GS-6615) on Exercise Capacity in Subjects With Symptomatic Hypertrophic Cardiomyopathy (LIBERTY-HCM)

Hypertrophic Cardiomyopathy

Australia, United States, Netherlands, Israel, Italy, France, Germany, United Kingdom
Bristol-Myers Squibb

Recruiting

A Study to Evaluate Mavacamten Impact on Myocardial Structure in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy (MEMENTO)

Cardiomyopathy, Hypertrophic

United States, Argentina, Australia, Belgium, Canada, Czechia, Hungary, Poland, Switzerland, France, Austria, Finland, Germany, Greece, Italy, Spain, United Kingdom
University of Edinburgh
Sir Jules Thorn Charitable Trust

Active, not recruiting

Early Valve Replacement Guided by Biomarkers of LV Decompensation in Asymptomatic Patients With Severe AS (EVoLVeD)

Aortic Valve Stenosis | Hypertrophy, Left Ventricular

United Kingdom
Oregon Health and Science University

Completed

Hypertrophic Cardiomyopathy Pilot Study

Coronary Artery Disease | Hypertrophic Cardiomyopathy

United States
University of Dundee
British Heart Foundation; NHS Tayside; NHS Greater Glasgow and Clyde; University...

Completed

Does ALlopurinol Regress lefT Ventricular Hypertrophy in End Stage REnal Disease: The ALTERED Study (Altered)

End Stage Renal Disease | Left Ventricular Hypertrophy

United Kingdom
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Signs and Symptoms of Genetic Abnormalities Linked to Inherited Heart Disease

Cardiomyopathy, Hypertrophic, Familial

United States
Bristol-Myers Squibb

Active, not recruiting

A Study of Mavacamten in Non-Obstructive Hypertrophic Cardiomyopathy (ODYSSEY-HCM)

Cardiomyopathy, Hypertrophic

Spain, Austria, Belgium, Brazil, Canada, Denmark, France, Germany, Hungary, Israel, Japan, Netherlands, Norway, Poland, Portugal, United Kingdom, United States, Australia, China, Czechia, India, Italy, Korea, Republic of
The Cleveland Clinic

Recruiting

A Cardiac Disease Quality of Life Study (UPLIFT)

Quality of Life | Hypertrophic Obstructive Cardiomyopathy | Thoracic Aortic Dilatation | Heart Disease Caused by Ionising Radiation

United States
University Hospital Birmingham
Brighton and Sussex University Hospitals NHS Trust; British Heart Foundation; University of Birmingham

Unknown

Myocardial Protection With Perhexiline in Left Ventricular Hypertrophy (HYPER)

Myocardial Reperfusion Injury | Hypertrophy, Left Ventricular | Cardiac Output, Low

United Kingdom
Bristol-Myers Squibb

Recruiting

A Study to Evaluate the Efficacy, Safety, and Tolerability of MYK-224 in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy (MERCUTIO)

Cardiomyopathy, Hypertrophic

United States, Poland, Spain, Italy
Jean-Luc Balligand
University of Oxford; University of Athens; Cliniques universitaires Saint-Luc-... and other collaborators

Active, not recruiting

Assessment of Efficacy of Mirabegron, a New beta3-adrenergic Receptor in the Prevention of Heart Failure (Beta3_LVH)

Hypertrophy, Left Ventricular

Belgium, France, Germany, Greece, Italy, Poland, Portugal, United Kingdom
St George's, University of London
Guy's and St Thomas' NHS Foundation Trust

Unknown

Vitamin D Supplementation and Cardiac Hypertrophy in Chronic Kidney Disease (CKD) (5C)

Chronic Kidney Disease

United Kingdom
Heart Metabolics Limited

Terminated

Open-Label Study of Perhexiline in Patients With Hypertrophic Cardiomyopathy and Moderate to Severe Heart Failure

Cardiomyopathy, Hypertrophic | Cardiomyopathy, Hypertrophic, Familial

United States
Brigham and Women's Hospital
Baylor College of Medicine; Duke University; National Human Genome Research Institute...

Completed

A Pilot Project Exploring the Impact of Whole Genome Sequencing in Healthcare

Healthy Adults (Full Study and Extension Phase) | Hypertrophic Cardiomyopathy or Dilated Cardiomyopathy

United States
iRhythm Technologies, Inc.

Completed

Extended ECG Monitoring in HCM Patients (EXAMINE-HCM)

Atrial Fibrillation | Arrhythmia | Ventricular Tachycardia | Hypertrophic Cardiomyopathy | Nonsustained Ventricular Tachycardia

United States
The Cleveland Clinic

Completed

Genomic Sequencing in Patients With HCM Undergoing Septal Myectomy

Hypertrophic Cardiomyopathy | Genetic Disease | Gene Product Sequence Variation

United States
Rhode Island Hospital

Completed

Lidocaine Infusion for Pain Relief in Children Scheduled for Tonsillectomy and Adenoidectomy

Children, Only | Tonsillar Hypertrophy | Adenoid Hypertrophy

United States
Yale University
National Heart, Lung, and Blood Institute (NHLBI); National Institutes of Health...

Completed

Exercise in Genetic Cardiovascular Conditions (LIVE-HCM/LQT)

Hypertrophic Cardiomyopathy | Long QT Syndrome

United States, United Kingdom, Canada, Australia, New Zealand
Olubukola Nafiu

Enrolling by invitation

Metabolomic Profiling of Racial Disparity

Surgery | Tonsillar Hypertrophy | Adenoid Hypertrophy

United States
University Hospital Birmingham NHS Foundation Trust

Completed

Effects of a Reduction in Renal Function on Cardiovascular Structure and Function (CRIB-DONOR II)

Hypertension | Chronic Kidney Disease | Hypertrophy, Left Ventricular

United Kingdom
Mayo Clinic

Completed

Biomarkers in Aortic Stenosis - B.A.S.S. (BASS)

Aortic Stenosis | Mitral Valve Insufficiency | Aortic Valve Insufficiency | Hypertrophic Cardiomyopathy | Tricuspid Valve Insufficiency | Disorder of Prosthetic Cardiac Valve

United States
University of California, Irvine

Withdrawn

The Genetics of Cardiomyopathy and Heart Failure

Dilated Cardiomyopathy | Hypertrophic Cardiomyopathy | Restrictive Cardiomyopathy | Mitochondrial Cardiomyopathy | Noncompaction Cardiomyopathy

United States
Olix Pharmaceuticals, Inc.

Completed

A Study to Evaluate Safety and PK Profiles of OLX10010 in Healthy Subjects

Cicatrix, Hypertrophic

United Kingdom
Royal Marsden NHS Foundation Trust
King's College London; University College, London; Institute of Cancer Research... and other collaborators

Recruiting

A Study Comparing Urolift and TURP Ahead of Radiotherapy in Men With Urinary Symptoms Secondary to Prostate Enlargement (CO-STAR)

Prostate Cancer

United Kingdom
Brigham and Women's Hospital
National Institutes of Health (NIH); National Library of Medicine (NLM)

Unknown

Refining Information Technology Support for Genetics in Medicine (RISGIM)

Cancer | Hearing Loss | Hypertrophic Cardiomyopathy

United States, Canada
Marymount University
University of Tehran

Completed

Resistance Training and Milk Supplementation

Muscular Hypertrophy

United States
Medstar Health Research Institute
Latham Fund

Recruiting

Treatment of Hypopigmented Scars With Bimatoprost

Burn Scar | Cicatrix | Scars | Cicatrix, Hypertrophic | Pigmentation Disorder | Scarring | Hypopigmented Skin | Hypopigmented Scar | Burns Laser

United States
Arlyne Thung

Completed

A Pilot Study: a Non-opioid Technique for Postoperative Adenoidectomy Pain Relief in Pediatric Patients

Adenoid Hypertrophy

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Analysis of Heart Muscle Function in Patients With Heart Disease and Normal Volunteers

Myocardial Ischemia | Coronary Disease | Healthy | Cardiomyopathy, Hypertrophic | Syndrome X

United States
Pierre-Yves P Lequeux

Completed

Opioid-sparing Effect of Intranasal Dexmedetomidine

Tonsillar Hypertrophy

United Arab Emirates

Clinical Trials on Hypertrophy in United Kingdom

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