Resistance Training and Milk Supplementation

Effects of High-protein Milk Supplementation on Muscular Strength and Power, Body Composition, and Skeletal Muscle Regulatory Markers Following Heavy Resistance Training in Resistance-trained Men

Post-resistance training high protein milk supplementation may be a viable method to elicit muscular gains.

The investigators hypothesis is that high protein milk supplementation would improve skeletal regulatory markers, hormonal responses and body composition in resistance-trained men.

Study Overview

• Status: Completed
• Conditions: Muscular Hypertrophy
• Intervention / Treatment: Dietary supplement: high protein milk; Dietary supplement: Placebo

Detailed Description

The aim of this investigation was to compare the effects of high protein milk supplementation (daily and after training sessions) during 6 weeks of resistance training on skeletal muscle regulatory markers, hormonal responses and body composition in resistance-trained men. Specific aims of the study are to:

To investigate the extent to which high protein milk supplementation will improve anabolic factors, lean body mass, fat mass and decrease catabolic markers after 6 weeks of resistance training in resistance-trained men.

• Study Type: Interventional
• Enrollment (Actual): 30
• Phase: Not Applicable

Contacts and Locations

Study Locations

• United States
  • Virginia
    • Arlington, Virginia, United States, 22207
      • Marymount University

Participation Criteria

Eligibility Criteria

• Ages Eligible for Study: 18 years to 35 years (ADULT)
• Accepts Healthy Volunteers: Yes
• Genders Eligible for Study: Male

Description

Inclusion Criteria:

• Aged 18-35 years of age
• Healthy Males
• Experienced at resistance training (at least 1 year of prior structured resistance training 3 x week).

Exclusion Criteria:

• smoking
• chronic alcohol consumption
• having any medical issues and diseases
• lactose intolerance
• the consumption of any dietary supplements (including vitamins or protein supplements) or medications for 6 months prior to participation

Study Plan

How is the study designed?

Design Details

• Primary Purpose: BASIC_SCIENCE
• Allocation: RANDOMIZED
• Interventional Model: PARALLEL
• Masking: DOUBLE

Number of Arms

2

Arms and Interventions

Participant Group / Arm	Intervention / Treatment
EXPERIMENTAL: High protein milk; Experimental: High protein milk consumption This arm involved High protein milk whole consumption concomitant with 6 weeks of resistance training. Subject ingested consumed 1 x 250 mL immediately after resistance training and 1 x 250 mL half an hour before bedtime.	Dietary supplement: high protein milk; This intervention consisted of high protein milk consumption concomitant with 6 weeks of resistance training. Subject ingested consumed 1 x 250 mL immediately after resistance training and 1 x 250 mL half an hour before bedtime.; Dietary supplement: Placebo; This intervention consisted of the consumption of a maltodextrin drink with a 9% solution with a vanilla flavor concomitant with 6 weeks of resistance training. Subject ingested consumed 1 x 250 mL immediately after resistance training and 1 x 250 mL half an hour before bedtime.
PLACEBO_COMPARATOR: Placebo; This arm involved consumption of a maltodextrin drink with a 9% solution with a vanilla flavor concomitant with 6 weeks of resistance training. Subject ingested consumed 1 x 250 mL immediately after resistance training and 1 x 250 mL half an hour before bedtime. drink r	Dietary supplement: high protein milk; This intervention consisted of high protein milk consumption concomitant with 6 weeks of resistance training. Subject ingested consumed 1 x 250 mL immediately after resistance training and 1 x 250 mL half an hour before bedtime.; Dietary supplement: Placebo; This intervention consisted of the consumption of a maltodextrin drink with a 9% solution with a vanilla flavor concomitant with 6 weeks of resistance training. Subject ingested consumed 1 x 250 mL immediately after resistance training and 1 x 250 mL half an hour before bedtime.

What is the study measuring?

Primary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Circulatory Myokines levels	Fasting blood samples were collected from the antecubital vein using standard procedures and then analyzed to establish concentration of myostatin and follistatin.	6 weeks
Circulatory hormone levels	Fasting blood samples were collected from the antecubital vein using standard procedures and then analyzed to establish concentrations of testosterone, IGF-1, growth hormone, insulin and cortisol	6 weeks
Body composition	Lean body mass and body fatness will be evaluated using bioelectrical impedance	6 weeks

Secondary Outcome Measures

Outcome Measure	Measure Description	Time Frame
Muscular Strength	Using a 1 repetition maximum test (defined as the maximal weight an individual can lift for only one repetition) for the bench press and back squat exercises	6 weeks
Muscular Power	Using the Wingate test	6 weeks

Collaborators and Investigators

• Sponsor: Marymount University
• Collaborators: University of Tehran

Study record dates

Study Major Dates

• Study Start (ACTUAL): January 4, 2018
• Primary Completion (ACTUAL): May 5, 2018
• Study Completion (ACTUAL): May 5, 2018

Study Registration Dates

• First Submitted: August 5, 2020
• First Submitted That Met QC Criteria: August 10, 2020
• First Posted (ACTUAL): August 12, 2020

Study Record Updates

• Last Update Posted (ACTUAL): August 12, 2020
• Last Update Submitted That Met QC Criteria: August 10, 2020
• Last Verified: August 1, 2020

More Information

Terms related to this study

• Keywords: body composition; milk; Hypertrophy; resistance training
• Additional Relevant MeSH Terms: Pathological Conditions, Anatomical; Hypertrophy
• Other Study ID Numbers: Sports sciences institute.1396

Plan for Individual participant data (IPD)

• Plan to Share Individual Participant Data (IPD)?: NO

Drug and device information, study documents

• Studies a U.S. FDA-regulated drug product: No
• Studies a U.S. FDA-regulated device product: No