Clinical Trials on Hyponatremia

Total 175 results

Medical Centre Leeuwarden
University Medical Center Groningen

Completed

Investigation on Differences in Skin Sodium Content Between Normal Subjects and ICU-patients (InCa)

Hypernatremia

Netherlands
Cumberland Pharmaceuticals

Completed

Study to Compare Conivaptan Pharmacokinetics in Subjects With Mild & Moderate Kidney Function Impairment to Subjects With Normal Kidney Function

Kidney Diseases | Hyponatremia

United States
University of Delaware

Recruiting

Dietary Sodium, Oxidative Stress, and Pulsatile Hemodynamics

Sodium Excess

United States
Medical Centre Leeuwarden

Completed

Hydrochloorthiazide and Hypernatriaemie

Hypernatraemia

Netherlands
University of Calgary

Terminated

Tolvaptan for Advanced or Refractory Heart Failure

Heart Failure | Hyponatremia

Canada
Finn Gustafsson
Rigshospitalet, Denmark

Unknown

The Effect of Fluid Restriction in Congestive Heart Failure Complicated With Hyponatremia (Decongest)

Heart Failure | Hyponatremia

Denmark
Beijing Friendship Hospital
Chinese University of Hong Kong

Completed

Efficacy and Safety of Tolvaptan in Cirrhotic Patients With Hyponatremia (OASIS)

Liver Cirrhosis | Hyponatremia

China
Rajavithi Hospital

Unknown

Efficacy and Safety of Bolus Comparing With Continuous Drip of 3% NaCl in Patients With Severe Symptomatic Hyponatremia.

Hyponatremia | Osmotic Demyelination Syndrome

Thailand
Cumberland Pharmaceuticals

Terminated

Safety and Efficacy of Conivaptan in Hyponatremic Patients With Symptomatic Acute Decompensated Heart Failure (ADHF) (CONVERT-H)

Acute Decompensated Heart Failure | Hyponatremia

India
Institute of Liver and Biliary Sciences, India

Recruiting

To Study Effect of the Combination of Midodrine and Tolvaptan Versus Tolvaptan Alone in Patients With Severe Hyponatremia in Cirrhosis(TOLMINA Trial)

Liver Cirrhosis

India
Sanofi

Completed

DILIPO (DILutIonal HyPOnatremia)

Congestive Heart Failure

United States, Canada, Poland, Romania, Portugal, Sweden, Belgium, Argentina, Denmark, Hungary, Israel, Australia, Chile, South Africa, Greece
Centre Hospitalier Universitaire de Besancon

Unknown

ED Hypernatremia. Prognostic Factors and Epidemiology. (NATSAU)

Hypernatremia

France
Catharina Ziekenhuis Eindhoven

Completed

Prospective Data Analysis of the Development of Hypernatremia in Intensive Care Unit (HYPNIC)

Hypernatremia

Netherlands
Polderman, Kees, H., MD, PhD
University of Pittsburgh

Terminated

Tolvaptan for Patients With Acute Neurological Injuries

Hyponatremia | SIADH

United States
University of Wuerzburg

Completed

Subclassification of the Syndrome of Inappropriate ADH Secretion

Hyponatremia

Germany
Centre Hospitalier Arras

Completed

Relieve the Patient's Thirst, Refresh the Mouth First (ICU-MIC) (ICU-MIC)

Dehydration | Hypernatremia

France
Texas Tech University
American Society for Nutrition

Not yet recruiting

Increasing Vegetable Intake Using Monosodium Glutamate: A Reduced-Effort Intervention

Sodium Excess | Healthy Nutrition | Culinary Medicine
Federico II University

Completed

Low Sodium Neapolitan Pizza Prepared With Seawater: Nutritional Properties, Sensory Characteristics, Metabolic Effects

Satiety Response | Sodium Retention | Carbohydrate Metabolism

Italy
Rigshospitalet, Denmark

Completed

The Association Between Hyponatremia and Osteoporosis in Patients With Epilepsy.

Hyponatremia | Metabolic Bone Disease

Denmark
Auburn University
University of Delaware

Recruiting

Racial Differences in Serum Sodium and Blood Pressure Regulation

Blood Pressure | Cardiovascular Risk Factor | Sodium Excess | Racial Disparities

United States
University of North Carolina, Chapel Hill
Medical University of South Carolina; Otsuka America Pharmaceutical; Barnes-Jewish...

Terminated

Pharmacokinetics and Clinical Response of Tolvaptan in Neurocritical Care Patients

Brain Injury | Hyponatremia

United States
Ege University

Recruiting

Investigation of the Effect of Distention Medium Temperature on Image Quality, Hyponatremia Risk, and Post-operative Pain in Operative Hysteroscopy

Post-operative Pain

Turkey
Konkuk University Medical Center
Samsung Medical Center; Seoul St. Mary's Hospital; Korea University Anam Hospital and other collaborators

Unknown

Tolvaptan for Hyponatremia in Cirrhotic Patients With Ascites (TONIC)

Ascites | Hyponatremia

Korea, Republic of
Catharina Ziekenhuis Eindhoven

Not yet recruiting

Prospective Analysis Into Development of Hypernatremia in Critically Ill Patients (HYPNIC II)

Critical Illness | Hypernatremia

Netherlands
University of Sao Paulo

Unknown

Safety and Efficacy of Hydrochlorothiazide in the Treatment of Hypernatremia in Critically Ill Patients (HYDRA)

Critical Illness | Hypernatremia

Brazil
University Hospital Freiburg
Stanford University; Heidelberg University

Not yet recruiting

A Short, Animated Storytelling Video to Increase Knowledge About Sodium Intake as a Cardiovascular Risk Factor

Cardiovascular Risk Factor | Sodium Excess | Education Entertainment Intervention | Short, Animated Storytelling
Navitas Pharma
IndiPharm Inc.

Not yet recruiting

Cicletanine in Hypertension With Diabetes: Added Magnesium Preserves Potassium and Sodium (CHAMP)

Diabetes | Hyponatremia | Arterial Hypertension | Hypokalemia
University of Sao Paulo
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Hypertonic Saline Solution in Heart Failure

Heart Failure | Renal Failure | Hyponatremia

Brazil
University Hospital, Caen

Completed

Delirium Related to Proton Pump Inhibitors Use

Delirium | Hyponatremia | Proton Pump Inhibitor Adverse Reaction

France
Universitair Ziekenhuis Brussel

Recruiting

Asymptomatic Bacteriuria, Hyponatremia and Geri-atric Syndrome

Frailty | Asymptomatic Bacteriuria | Geriatric Syndrome | SIADH

Belgium
Air Force Military Medical University, China

Unknown

Continuous Venovenous Hemofiltration Versus Conventional Treatment for Acute Severe Hypernatremia

Critically Ill | Hypernatremia

China
Helbert Rondon Berrios, MD, MS
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Terminated

Urea for Chronic Hyponatremia

Hyponatremia | Inappropriate ADH Syndrome

United States
University Hospital, Basel, Switzerland

Completed

Effects of Empagliflozin an SGLT2-Inhibitor on Healthy Volunteers With Induced Hypotonic Hyponatremia - the DIVE Study (DIVE)

Inappropriate ADH Syndrome

Switzerland
University Hospital, Grenoble

Recruiting

Urea Therapy for Hyponatremia in Subarachnoid Hemorrhage (NAT-URE)

Subarachnoid Hemorrhage | Hyponatremia | SIADH

France
Hospices Civils de Lyon

Completed

Seizures in Infants Hospitalized in Pediatric Intensive Care Unit for Bronchiolitis (BRONCHIOLITIS)

Seizures | Hyponatremia | Bronchiolitis

France
University of Connecticut
United States Department of Defense; AMP Human; Park City, UT

Completed

The Effect of AMP Human Sodium Bicarbonate Lotion on Hydration (AMPlify)

Cognitive Change | Electrolyte and Fluid Balance Conditions | Fluid Retention | Heat Exposure | Fluid Loss | Hyperhydration | Sodium Retention

United States
Hospital Nacional Profesor Alejandro Posadas

Recruiting

Prevalence of Hyponatremia in Dengue Infected Patients: Relationship With Systemic Inflammation. (HINDIP)

Inflammation | Hyponatremia | Dengue

Argentina
University Hospital Inselspital, Berne
University Hospital, Geneva; University of Lausanne Hospitals

Terminated

Treatment of Sodium Retention in Liver Cirrhosis With Dexamethasone

Liver Cirrhosis

Switzerland
Centre Hospitalier Universitaire, Amiens

Recruiting

Association Between Renal and Right Cardiac Functions After Urinary Sodium Depletion Following Cardiac Surgery (DECONGEST)

Cardiorenal Syndrome

France
University Hospital, Basel, Switzerland

Completed

Effects of the SGLT2-inhibitor Empagliflozin on Patients With Chronic SIADH - the SANDx Study (SANDx)

Hyponatremia | SIAD - Syndrome of Inappropriate Antidiuresis

Switzerland
University Hospital, Basel, Switzerland

Recruiting

Effects of Intravenous [Pyr1]Apelin-13 on Healthy Volunteers With Artificially Induced SIAD (ESCAPE)

Hyponatremia | SIAD - Syndrome of Inappropriate Antidiuresis

Switzerland
Otsuka Pharmaceutical Europe Ltd

Completed

An Observational Study to Describe the Adherence to the SEOM Algorithm for the Treatment of Hyponatraemia in Spain (ALGA)

Hyponatremia | Syndrome of Inappropriate ADH (SIADH) Secretion

Spain
Otsuka Pharmaceutical Europe Ltd

Completed

An Observational Study on Real-world Use and Outcomes of Patients Treated With Tolvaptan for Hyponatraemia Due to SIADH (SAMPLE)

Hyponatremia | Syndrome of Inappropriate ADH (SIADH) Secretion

Germany, Spain
Thomas Jefferson University

Unknown

Safety and Feasibility of Hypertonic Saline Solution After Aneurysmal Subarachnoid Hemorrhage: (HS3)

Subarachnoid Hemorrhage | Hyponatremia | Cerebral Vasospasm

United States
Oregon Health and Science University

Withdrawn

Stop Hypernatremia, Use Metolazone, for Aggressive, Controlled, Effective Diuresis (SHUM)

Respiratory Failure | Hypernatremia | Volume Overload

United States
Otsuka Pharmaceutical Europe Ltd

Completed

An Observational Study Measuring Outcomes in Cancer Patients Treated for Moderate to Severe Hyponatremia in Italy (ASSERT)

Cancer | Hyponatremia | Syndrome of Inappropriate ADH (SIADH) Secretion

Italy
Ankara University

Completed

Hyponatremia and Hypoalbuminemia is Morbimortality Predictors in Coronary Artery Bypass Graft Surgery

Coronary Artery Disease | Hyponatremia | Hypoalbuminemia
Hospital Nacional Profesor Alejandro Posadas

Completed

HYPONATREMIA IN COVID-19 PATIENTS

Covid19 | Corona Virus Infection | Hyponatremia

Argentina
Ankara City Hospital Bilkent

Completed

Effect of Hyponatremia in Small Cell Lung Cancer

Small Cell Lung Cancer
Sanofi

Terminated

A Phase III Study Evaluating the Efficacy and Safety of Satavaptan Versus Placebo in Patients With Dilutional Hyponatremia (AQUARIST1)

Hyponatremia | Inappropriate ADH Syndrome

United States

Clinical Trials on Hyponatremia

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Georgia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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