Clinical Trials on Hypothermic Machine Perfusion in South Africa

Total 48 results

PATH
Bill and Melinda Gates Foundation; Children's Hospital Medical Center, Cincinnati and other collaborators

Completed

Mixed Schedule Study of Live Oral Rotavirus Vaccines and Trivalent P2-VP8 Subunit Rotavirus Vaccine

Rotavirus Vaccine

South Africa
PATH

Completed

Phase I/II Descending Age Study of P2VP8 Subunit Parenteral Rotavirus Vaccine in Healthy Toddlers and Infants

Evaluation of a Rotavirus Vaccine

South Africa
University of Cape Town
Population Health Research Institute; Walter Sisulu University

Unknown

IMPI 2 - A Trial of Intrapericardial Alteplase in Large Pericardial Effusion (IMPI-2)

Pericardial Effusion

South Africa
Nkanyiso Hadebe

Unknown

Cardiac REperfusion With Intralipid® at Reperfusion (CREW-I)

Reperfusion Injury

South Africa
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Study Evaluating a 13-valent Pneumococcal Conjugate Vaccine in Elderly Subjects

Vaccines, Pneumococcal Conjugate Vaccine

South Africa
University of Cape Town
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

B. Infantis Supplementation to Improve Immunity in Infants Exposed to HIV (BifIID)

Vaccine Reaction | Hiv | Microbial Colonization | Infant Development

South Africa
Farzanah Laher
Sanofi

Active, not recruiting

Pertussis Vaccination Among HIV-infected and HIV-uninfected Pregnant Women

dTap Vaccine

South Africa
Medical University of South Carolina
Guerbet

Recruiting

Dotarem Evaluation for Myocardial Perfusion CMR

Magnetic Resonance Imaging | Myocardial Perfusion Imaging

United States
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Active Warming During Elective Caesearean Section

Preoperative Hypothermia

United Kingdom
HIV Vaccine Trials Network
South Africa AIDS Vaccine Initiative

Completed

Safety of and Immune Response to a DNA HIV Vaccine Boosted With a Modified Vaccinia HIV Vaccine and Protein HIV Vaccine in Healthy Adults

HIV Seronegativity | HIV Preventive Vaccine

South Africa
Medical University of South Carolina

Completed

Observational Examination of Thermoregulation in Total Joint Arthroplasty

Hypothermia

United States
Sanofi Pasteur, a Sanofi Company

Completed

Study to Evaluate the Immune Response After Booster Vaccination With Tdap-IPV Vaccine (Against Tetanus, Diphtheria, Pertussis and Poliomyelitis) in Children Who Received Different Pertussis Primary Vaccine Regimens in Republic of South Africa

Pertussis Immunisation | Diphtheria Immunisation | Tetanus Immunisation | Poliomyelitis Vaccine

South Africa
Bilix Co.,Ltd.

Recruiting

A Study to Evaluate the Safety and Pharmacokinetics of BX-001N in Healthy Participants

Ischemia-reperfusion Injury

Australia
University of Cape Town
University College, London; Kenyatta National Hospital; Uganda Heart Institute; Grey's Hospital and other collaborators

Recruiting

Remote Ischaemic Conditioning in STEMI Patients in Sub-Saharan AFRICA (RIC-AFRICA)

Myocardial Reperfusion Injury | STEMI | Remote Ischaemic Conditioning

Kenya, Uganda, South Africa, Sudan
BioSyngen Pte Ltd

Unknown

A Study of Syngenon (BSG-001) for Inhalation in Subjects With Malignant Pleural Effusion and/or Malignant Ascites

Malignant Ascites | Malignant Pleural Effusion

Australia
Otonomy, Inc.

Completed

Open-Label Study of OTO-201 for Middle Ear Effusion Evaluating Trans-Tympanostomy Tube Administration

Bilateral Middle Ear Effusion

United States
Duke University
University of South Carolina

Completed

Increase Vaccine Uptake in Adolescent in Rural South (INVEST)

Vaccine Hesitancy

United States
Clover Biopharmaceuticals AUS Pty Ltd

Completed

Study With SCB-313 (Recombinant Human TRAIL-Trimer Fusion Protein) for Treatment of Malignant Pleural Effusions

Malignant Pleural Effusions

Australia
Providence Therapeutics Holdings Inc.

Completed

PTX-COVID19-B, an mRNA Humoral Vaccine, Intended for Prevention of COVID-19 in a General Population. This Study is Designed to Demonstrate the Safety, Tolerability, and Immunogenicity of PTX-COVID19-B in Comparison to the Pfizer-BioNTech COVID-19 Vaccine.

Covid19 Vaccine

Canada, South Africa
Pfizer

Completed

A Trial to Describe the Safety and Immunogenicity of MenABCWY When Administered on 2 Schedules

Meningococcal Vaccine

United States
EyeGene Inc.
Novotech (Australia) Pty Limited

Active, not recruiting

Study to Assess the Safety, Tolerability and Explore the Immunogenicity of EG-COVID and EG-COVARo in Healthy Adult Volunteers

COVID-19 Vaccine

Australia
Tusker Medical

Completed

Adult Study to Evaluate Placement of Tympanostomy Tubes In-office (ADEPT) (ADEPT)

AOM - Acute Otitis Media | Eustachian Tube Dysfunction | Barotrauma;Ear | OME - Otitis Media With Effusion

United States
South Australian Health and Medical Research Institute
University of Sydney; Telethon Kids Institute; Flinders University; Royal Adelaide... and other collaborators

Recruiting

Antibiotics and Vaccine Immune Responses Study (AVIRS)

Vaccine Response Impaired

Australia
Phoenix Children's Hospital
National Institutes of Health (NIH)

Terminated

Hypothermia in Children After Trauma

Traumatic Brain Injury

United States, Australia, Canada, New Zealand, South Africa, United Kingdom
Pfizer

Completed

MenABCWY Noninferiority Study in Healthy Participants ≥10 to <26 Years of Age

Meningococcal Vaccine

United States, Denmark, Hungary, Czechia, Poland
Tusker Medical

Completed

In-Office Tympanostomy Tube Placement in Children (OTTER) (OTTER)

AOM - Acute Otitis Media | OME - Otitis Media With Effusion

United States, Canada
Medical University of South Carolina

Recruiting

Hypothermia's Effect on Hepatitis B Vaccination

Hepatitis B Vaccination | Hypoxic-Ischemic Encephalopathy | Hypothermia, Newborn

United States
Australia and New Zealand Intensive Care Society

Completed

Hypothermia in Traumatic Brain Injury in Children (HiTBIC)

Traumatic Brain Injury

Australia, New Zealand
Philips Clinical & Medical Affairs Global

Completed

Point of Care Ultrasound Lung Artificial Intelligence (AI) Validation Data Collection Study (AI)

Pleural Effusion | Lung Consolidation

United States
Chung Shan Medical University
Ministry of Education, Taiwan

Completed

Enhancing Respiratory Auscultation Skills Among Medical Students: Digital Stethoscopes in Medical Education

Pneumonia | Asthma | Pleural Effusion | Breathing Sound | Auscultation

Taiwan
Dynavax Technologies Corporation

Completed

Trial to Evaluate the Safety, Tolerability, and Immunogenicity of an Investigational Herpes Zoster Vaccine (Z-1018) Compared to Shingrix® in Healthy Adult Volunteers

Herpes Zoster | Vaccine-Preventable Diseases | Shingles

Australia
Pfizer

Completed

A Trial to Describe the Immunogenicity and Safety of 2 Doses of Bivalent rLP2086 (Trumenba) and a Pentavalent Meningococcal Vaccine in Healthy Subjects >=10 to <26 Years of Age.

Meningococcal Vaccine

United States, Finland, Czechia, Poland
National Cancer Institute (NCI)

Completed

Erlotinib Hydrochloride With or Without Carboplatin and Paclitaxel in Treating Patients With Stage III-IV Non-small Cell Lung Cancer

Lung Adenocarcinoma | Minimally Invasive Lung Adenocarcinoma | Malignant Pleural Effusion | Stage IIIB Lung Non-Small Cell Cancer AJCC v7 | Stage IV Lung Non-Small Cell Cancer AJCC v7 | Malignant Pericardial Effusion | Lung Adenosquamous Carcinoma

United States
University of South Carolina
Prisma Health-Midlands; The Gerber Foundation

Recruiting

Blood Warming in Preterm Infants to Decrease Hypothermia

Preterm Birth | Hypothermia | Blood Transfusion Complication

United States
Johns Hopkins University
Medical University of South Carolina; Vanderbilt University Medical Center; University... and other collaborators

Recruiting

Gravity Versus Vacuum Based Indwelling Tunneled Pleural Drainage System (NEWTON)

Pleural Effusion

United States, United Kingdom
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI); Eastern Cooperative Oncology Group; Radiation... and other collaborators

Completed

Talc in Treating Patients With Malignant Pleural Effusion

Metastatic Cancer

United States, Canada
University of Miami
United States Department of Defense

Recruiting

Systemic Hypothermia in Acute Cervical Spinal Cord Injury

Spinal Cord Injury, Acute

United States
Bilthoven Biologicals
Serum Institute of India Pvt. Ltd.

Completed

A Clinical Study Comparing Safety and Immunogenicity of bOPV of Bilthoven Biologicals

Immune Response to Oral Polio Vaccine

Bangladesh
Helsingborgs Hospital
Lund University; Region Skåne - Skånevård SUND; Copenhagen Trial Unit, Center... and other collaborators

Completed

Targeted Hypothermia Versus Targeted Normothermia After Out-of-hospital Cardiac Arrest (TTM-2)

Out-of-hospital Cardiac Arrest

Norway, Sweden, Denmark, France, New Zealand, United Kingdom, Belgium, United States, Australia, Austria, Czechia, Germany, Italy, Switzerland
DynPort Vaccine Company LLC, A GDIT Company

Completed

Randomized Single-Blinded Study to Evaluate Safety and Immunogenicity of Recombinant Plague Vaccine With and Without Adjuvant

Plague Vaccine

United States
Novartis Pharmaceuticals

Completed

Non-small Cell Lung Cancer Registry

Pleural Effusion, Malignant | Non-Small-Cell Lung Cancer

United States
Masaryk University
University of Kiel; University of Giessen; F.D. Roosevelt Teaching Hospital with... and other collaborators

Unknown

Oral Side Effects of COVID-19 Vaccine

Covid19 | Vaccine Adverse Reaction | Oral Manifestations

Czechia, Germany, Slovakia
IDeA States Pediatric Clinical Trials Network
National Institutes of Health (NIH); University of Nebraska; University of Montana

Active, not recruiting

Improving Pediatric COVID-19 Vaccine Uptake Using an mHealth Tool (MoVeUP)

Telemedicine | Pediatric ALL | Vaccine Hesitancy | COVID-19 Vaccines

United States
Craig Anderson
Johns Hopkins University; Genentech, Inc.; The George Institute for Global Health...

Recruiting

Optimal Post Tpa-Iv Monitoring in Ischemic Stroke

Acute Ischemic Stroke Patients Receiving Reperfusion Therapy

Australia, United Kingdom, United States, Chile, China, Malaysia, Mexico
GlaxoSmithKline

Completed

Safety and Immunogenicity Study of GlaxoSmithKline (GSK) Biologicals' Measles, Mumps and Rubella (MMR) Vaccine (209762) Compared to Merck & Co., Inc.'s MMR Vaccine in Healthy Children 12 to 15 Months of Age

Measles; Mumps; Rubella | Measles-Mumps-Rubella Vaccine

United States, Finland, Taiwan, Estonia, Puerto Rico
GlaxoSmithKline

Completed

Study to Evaluate Efficacy, Safety and Immunogenicity of GlaxoSmithKline (GSK) Biologicals' Herpes Zoster (HZ) Vaccine GSK1437173A in Adults Aged 70 Years and Older

Herpes Zoster | Herpes Zoster Vaccine

United States, Australia, Spain, Finland, Germany, Japan, Taiwan, Canada, Sweden, Korea, Republic of, Czechia, Hong Kong, Mexico, Italy, Brazil, Estonia, France, United Kingdom
GlaxoSmithKline

Completed

Immunogenicity of GSKs' MMR Vaccine (209762) vs. M-M-R® II, When Given With Routine Vaccines at 12-15 Months of Age

Measles | Rubella | Mumps | Measles-Mumps-Rubella Vaccine

United States, Puerto Rico
GlaxoSmithKline

Completed

Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Combined Measles-mumps-rubella (MMR) Vaccine in Children in Their Second Year of Life

Measles | Rubella | Mumps | Measles-Mumps-Rubella Vaccine

Finland, Thailand, United States, Spain, Czechia, Puerto Rico, Malaysia

Clinical Trials on Hypothermic Machine Perfusion in South Africa

Sponsors and Collaborators

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