Clinical Trials on ICAS - Intracranial Atherosclerosis

Total 4987 results

Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Dotatate to Locate Coronary Plaques at High-risk of Myocardial Infarction (DOLPHIN)

Atheroscleroses, Coronary

Netherlands
Novartis Pharmaceuticals

Recruiting

A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients.

Primary Prevention of Atherosclerotic Cardiovascular Disease

United States, China, Italy, Spain, France, Netherlands, Poland, Switzerland, Taiwan, Greece, Thailand, Brazil, India, Hungary, Latvia, Mexico, Israel, Malaysia, Turkey, Argentina, Singapore, Australia, Belgium, Bulgaria, Denmark, Croatia, South... and more
Esperion Therapeutics, Inc.

Completed

Evaluation of Long-Term Safety and Tolerability of ETC-1002 in High-Risk Patients With Hyperlipidemia and High CV Risk (CLEAR Harmony)

Hypercholesterolemia | Atherosclerotic Cardiovascular Diseases

United States, United Kingdom, Germany, Poland, Netherlands, Canada
Icahn School of Medicine at Mount Sinai
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Study of Symptoms and Quality of Life in Patients With Implantable Cardiac Defibrillators (ICDs) and Their Caregivers

Quality of Life | Implantable Cardiac Defibrillators | ICDs

United States
Guy's and St Thomas' NHS Foundation Trust

Unknown

The Use of Subcutaneous Implantable Cardiac Defibrillators (ICDs) Following Extraction of Conventional ICDs (SUBTRACT)

Use of Subcutaneous ICDs Following Infection
Yale University

Completed

Pragmatic Trial of Messaging to Providers About Treatment of Hyperlipidemia (PROMPT-LIPID)

High Risk Atherosclerotic Cardiovascular Disease

United States
The First Affiliated Hospital with Nanjing Medical...

Recruiting

Evolocumab Added to Statin Therapy in Symptomatic Intracranial Atherosclerotic Stenosis (EAST-ICAS) (EAST-ICAS)

Stroke Patients With Symptomatic Intracranial Atherosclerotic Stenosis

China
David Grant U.S. Air Force Medical Center

Terminated

Assessment of Coronary Artery Calcium in Active Duty Enlisted Military Members With 10 or More Years of Service

Atherosclerosis | Plaque, Atherosclerotic

United States
Merck Sharp & Dohme LLC

Completed

Evaluate the Utility of 18FDG-PET as a Tool to Quantify Atherosclerotic Plaque (MK-0000-081 AM3)(COMPLETED)

Atherosclerotic Vascular Disease
Second Affiliated Hospital, School of Medicine,...

Withdrawn

Study of Urinary Kallikrein to Enhance Collateral Circulation in Symptomatic Intracranial Atherosclerosis

Intracranial Arteriosclerosis | Collateral Circulation | Anterior Cerebral Circulation Infarction

China
Clinical Operations WCN B.V.
Sanofi

Enrolling by invitation

Comparison of Two Lipid Management Strategies in Very High Risk Patients (PENELOPECTRL)

Atherosclerotic Cardiovascular Disease | STEMI | Non STEMI

Netherlands
Creighton University

Completed

Utility of Clinical Examination in the Noninvasive Prediction of Aortic Atheroma - A Prospective Study

Atherosclerosis

United States
Westside Medical Associates of Los Angeles
Regeneron Pharmaceuticals; University of Washington

Unknown

Assessment of Atherosclerotic Plaque Characteristics Change by DCE-MRI With Alirocumab

Atherosclerosis | Hyperlipidemia

United States
Asan Medical Center
Bayer

Recruiting

Effects of aSPIrin Versus Aspirin Plus Low-dose RIvaroxaban on Carotid aTherosclerotic Plaque Inflammation (SPIRIT)

Coronary Artery Disease | Peripheral Arterial Disease | Carotid Stenosis | Atherosclerosis of Artery

Korea, Republic of
Takeda

Withdrawn

Proof of Mechanism Study of MLN1202 on Atherosclerotic Inflammation in Participants With Stable Atherosclerotic Cardiovascular Disease

Atherosclerotic Cardiovascular Disease
Stanford University

Not yet recruiting

Notification of Incidental Coronary Artery Calcium in Patients With Atherosclerotic Cardiovascular Disease (NOTIFY-ASCVD) (NOTIFY-ASCVD)

Coronary Artery Calcification | ASCVD
University of Helsinki
University of Eastern Finland

Completed

The Influence of Dietary Plant Sterols and Plant Stanols on Cholesterol and Plant Sterol Levels in Atheromatous Plaques

Atherosclerosis

Finland
Novartis Pharmaceuticals

Not yet recruiting

VictORION-INCLUSION is a Multicenter, Randomized, Open Label, Study of Inclisiran + Usual Care vs Usual Care Alone in an Inclusive and Underrepresented Population at High Risk for or Diagnosed With ASCVD Within a Pragmatic EHR Framework. (V-INCLUSION)

Atherosclerotic Cardiovascular Disease
Istituti Clinici Scientifici Maugeri SpA
Società Italiana Cardiologia Ospedalità Accreditata (SICOA)

Recruiting

PAtients With Symptomatic Peripheral Artery Disease on Rivaroxaban-acetylsalicylic Acid Combination Therapy (PRO-PAS) (PRO-PAS)

Peripheral Atherosclerotic Disease

Italy
Novartis Pharmaceuticals

Completed

A Randomized Study to Evaluate the Effect of an "Inclisiran First" Implementation Strategy Compared to Usual Care in Patients With Atherosclerotic Cardiovascular Disease and Elevated LDL-C Despite Receiving Maximally Tolerated Statin Therapy (VICTORION-INITIATE) (V-INITIATE)

Atherosclerotic Cardiovascular Disease

United States
Montreal Heart Institute

Completed

Colchicine in Vascular Inflammation Assessed With PET Imaging (COLPET)

Atherosclerotic Vascular Disease

Canada
National Cerebral and Cardiovascular Center

Unknown

Atheroma Progression and Vulnerability Under Continuous Glucose Monitoring (OPTIMAL)

Coronary Atherosclerosis

Japan
University of Vermont
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Epidemiology of Vascular Inflammation & Atherosclerosis

Heart Diseases | Cardiovascular Diseases | Coronary Disease | Atherosclerosis | Coronary Arteriosclerosis | Cerebrovascular Accident | Cerebral Arteriosclerosis
Xiang Xie
Xinjiang Medical University

Not yet recruiting

Study on the Composite Endpoint Event of PCSK9 Inhibitor in Patients With Very High Risk of ASCVD and Cancer

Cancer | Atherosclerotic Cardiovascular Disease | ASCVD | Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor
Icahn School of Medicine at Mount Sinai
Massachusetts General Hospital; National Heart, Lung, and Blood Institute (NHLBI) and other collaborators

Completed

Cardiovascular Inflammation Reduction Trial - Inflammation Imaging Study (CIRT)

Atherosclerotic Cardiovascular Disease | Vascular Inflammation

United States, Canada
Aristotle University Of Thessaloniki

Completed

Diagnosis and Therapy of Vulnerable Atherosclerotic Plaque

Stroke | Metabolic Syndrome | Type 2 Diabetes | Carotid Atherosclerosis

Greece
AstraZeneca
The Cleveland Clinic; IQVIA RDS Inc.

Completed

Outcomes Study to Assess STatin Residual Risk Reduction With EpaNova in HiGh CV Risk PatienTs With Hypertriglyceridemia (STRENGTH)

Eligible Men or Women Considered High Risk for Atherosclerotic Cardiovascular Disease (CVD)

United States, Belgium, Italy, Netherlands, Denmark, Taiwan, Poland, Russian Federation, Korea, Republic of, Hungary, United Kingdom, China, New Zealand, Czechia, Australia, South Africa, Ukraine, Japan, Canada, Mexico, Lithuania, Estoni...
Novo Nordisk A/S

Completed

A Research Study Looking at the Effect of Food Intake on How the Medicine NN0385-0434 Behaves in the Body of Healthy Participants

Healthy Volunteers | Elevated Cholesterol | Established Atherosclerotic Cardiovascular Disease (ASCVD) or ASCVD Risk

Germany
Brigham and Women's Hospital

Terminated

The Effect(s) of Sevelamer Carbonate (Renvela) on Atherosclerotic Plaque Inflammation Judged by FDG-PET Scan

Inflammation | Cardiovascular Disease | Atherosclerosis | Hyperphosphatemia | Dialysis

United States
Massachusetts General Hospital

Completed

Indocyanine Green Fluorescence Uptake in Human Carotid Artery Plaque (BRIGHT-CEA)

Atherosclerosis | Carotid Stenosis | Atherosclerotic Plaque

United States
Universidade do Porto
University of Oxford; University of Edinburgh

Not yet recruiting

Screening Coronary Artery Disease Using artiFicial intelligencE in Non-contrast Computed Tomography (SAFE-CT)

Coronary Artery Disease | Coronary Atheroscleroses

Portugal
Korea University Guro Hospital

Recruiting

Concurrent OCT and FFR-guided PCI in CAD (OPTICARE-CAD)

Coronary Artery Disease | Image | Atheroscleroses, Coronary

Korea, Republic of
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cholesterol-Lowering Atherosclerosis Study (CLAS)

Myocardial Ischemia | Heart Diseases | Cardiovascular Diseases | Cerebrovascular Disorders | Coronary Disease | Arterial Occlusive Diseases | Atherosclerosis | Carotid Artery Diseases | Coronary Arteriosclerosis | Cerebral Arteriosclerosis
Abbott Point of Care

Not yet recruiting

Method Comparison Study for Measuring Potassium (K) and Ionized Calcium (iCa) in Blood

Potassium (K) and Ionized Calcium (iCa) in Capillary Whole Blood
Shanghai Zhongshan Hospital

Not yet recruiting

The Efficacy and Safety of Tofacitinib in Patients With Glucocorticoid Resistant ICIs-related Myocarditis

Glucocorticoid Resistant ICIs-related Myocarditis
Jordan Collaborating Cardiology Group

Terminated

Tracking of Lipid Lowering Therapy in Jordan (JoLLA)

Dyslipidemias | Atherosclerotic Cardiovascular Disease

Jordan
Sheba Medical Center
Carmel Medical Center; University Hospital Goettingen; CVPath Institute Inc.

Unknown

Physical,Histological,and Genetic Analyses of Lipid-rich Atherosclerotic Plaques

Peripheral Vascular Diseases | Atherosclerosis | Aortic Aneurysm

Israel
Diagram B.V.
Isala; St. Jude Medical Nederland B.V.

Completed

Optical Coherence Tomography Morphologic and Fractional Flow Reserve Assessment in Diabetes Mellitus Patients (COMBINE)

Coronary Artery Disease | Diabetes Mellitus | Coronary Atheroscleroses

Netherlands
Johns Hopkins University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Reducing Total Cardiovascular Risk in an Urban Community (COACH)

Heart Diseases | Cardiovascular Diseases | Coronary Disease | Hypertension | Diabetes Mellitus | Atherosclerosis | Cerebral Arteriosclerosis

United States
Novartis Pharmaceuticals

Completed

In Silico Study Assessing the Impact of Inclisiran on Major Adverse Cardiovascular Events in Patients With Established Cardiovascular Disease (SIRIUS)

Atherosclerotic Cardiovascular Disease

France
China National Center for Cardiovascular Diseases

Not yet recruiting

Natural History of Coronary Atherosclerosis (NASCENT)

Coronary Artery Disease Progression | Optical Coherence Tomography | Atherosclerotic Lesion | Radial Wall Strain
Ionis Pharmaceuticals, Inc.

Active, not recruiting

A Study of Olezarsen (ISIS 678354) in Participants With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease, or With Severe Hypertriglyceridemia

Cardiovascular Diseases | Atherosclerosis | Hypertriglyceridemia

United States, Spain, Italy, Denmark, Hungary, Netherlands, Canada, France, Poland, Bulgaria, Czechia, Portugal, Slovakia, Norway
Korea University Guro Hospital

Recruiting

Comprehensive Assessment of Interconnection Between Brain Emotional Activity and Coronary Plaque Instability

Inflammation | Atherosclerosis | Acute Coronary Syndrome | Emotional Stress | Atherosclerosis, Coronary | Hematopoiesis | Atherosclerosis Coronary Artery With Angina Pectoris | Atheroma; Heart

Korea, Republic of
Novartis Pharmaceuticals

Not yet recruiting

A Study to Investigate LDL-cholesterol Lowering With Inclisiran Compared to Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease.

Hypercholesterolemia
Esperion Therapeutics, Inc.

Completed

Assessment of the Long-Term Safety and Efficacy of Bempedoic Acid (CLEAR Harmony OLE)

Hypercholesterolemia | Atherosclerotic Cardiovascular Disease

United States
University of North Carolina, Chapel Hill
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Gene-by-Smoking Interactions and Risk of Atherosclerosis - Ancillary to ARIC

Heart Diseases | Cardiovascular Diseases | Coronary Disease | Peripheral Vascular Diseases | Atherosclerosis | Carotid Artery Diseases | Cerebrovascular Accident | Cerebral Arteriosclerosis
Beijing Tiantan Hospital

Recruiting

Drug Eluting Stenting and Aggressive Medical Treatment for Preventing Recurrent Stroke in Intracranial Atherosclerotic Disease Trial (DREAM-PRIDE)

Stroke | Intracranial Atherosclerotic Disease

China
Northwell Health

Active, not recruiting

The Young Heart Study

Coronary Artery Disease | Atherosclerotic Cardiovascular Disease

United States
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company

Completed

Treatment of High and Very High riSk Dyslipidemic pAtients for the PreveNTion of CardiOvasculaR Events (SANTORINI)

Cardiovascular Diseases | Dyslipidemia | Hypercholesterolemia | Atherosclerotic Cardiovascular Disease

Finland, Netherlands, Spain, Belgium, Sweden, Austria, United Kingdom, Switzerland, Denmark, France, Germany, Portugal, Italy, Ireland
Sanofi
Regeneron Pharmaceuticals

Completed

ODYSSEY Outcomes: Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab

Atherosclerotic Cardiovascular Disease

China, Hong Kong, Austria, Bulgaria, Norway, Peru, France, Japan, Spain, Lithuania, Philippines, Israel, Belgium, Croatia, Poland, Hungary, Chile, Mexico, Latvia, Singapore, Switzerland, Colombia, Greece, Ukraine, Turkey, Finland, United States and more

Clinical Trials on ICAS - Intracranial Atherosclerosis

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