Clinical Trials on Immune System Support

Total 191529 results

Lady Hardinge Medical College

Recruiting

Efficacy And Safety Of Short Course Antibiotic Therapy In Preterm Neonates With Early Onset Sepsis

Antibiotic Stewardship | Early-Onset Neonatal Sepsis

India
Assistance Publique - Hôpitaux de Paris
Advanz Pharma; Centre Hospitalier de Perigueux; CHU de Nantes; Centre National...

Recruiting

Dalbavancin Versus Standard Antibiotic Therapy for Catheter-related Bloodstream Infections Due to Staphylococcus Aureus (DALICATH)

Staphylococcus Aureus Infection | Catheter Bacteremia

France
Second Affiliated Hospital, School of Medicine,...

Not yet recruiting

Artificial Intelligence for Sepsis Prediction in ICU (AICUSepsis)

Septic Shock | Artificial Intelligence | Intensive Care Unit Psychosis
Emoled

Terminated

Effectiveness of the EmoLED Medical Device in the Healing of Digital Ulcers in Patients With Scleroderma. (SUITABLE)

Ulcer | Scleroderma | Digital Ulcer | Acral Nevus

Italy
University of Ljubljana

Completed

Loads, Injuries and Illnesses Among Elite Handball Players (PPDC-2022)

Athletic Injuries | Injuries | Psychological | Physical Stress | Physical Trauma | Social Stress | Physical Injury | Physical Illness | Illness, Chronic | Illnesses Systemic | Illnesses, Occupational

Slovenia
Michael Roth
University of California, Los Angeles; University of Michigan; Genentech, Inc.

Completed

Scleroderma Lung Study III - Combining Pirfenidone With Mycophenolate (SLSIII)

Scleroderma, Systemic | Interstitial Lung Disease

United States
Merck Sharp & Dohme LLC

Completed

Safety, Efficacy, and Pharmacokinetics (PK) of Daptomycin (MK-3009) in Japanese Pediatric Subjects With Complicated Skin and Soft Tissue Infections (cSSTI) and Bacteremia (MK-3009-029)

Skin Diseases, Infectious | Bacteremia | Soft Tissue Infections

Japan
Wuhan Union Hospital, China

Unknown

The Early Coagulopathy for the Prognosis in Sepsis

Sepsis | Outcome, Fatal | Coagulopathy
Assistance Publique - Hôpitaux de Paris
Centrale Supelec School (Center for Visual Computing)

Completed

MRI Quantification of Pulmonary Fibrosis in Scleroderma Patients (IRMSCLERO)

Scleroderma

France
Ohio State University
Alliance for Potato Research and Education

Unknown

Cardiometabolic Benefits of Potatoes Mediated Along the Gut-Vessel Axis in Adults With Metabolic Syndrome

Cardiovascular Diseases | Endotoxemia | Endothelial Dysfunction | Postprandial Hyperglycemia | Gut Health

United States
Virginia Commonwealth University
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Vitamin C Infusion for Treatment in Sepsis Induced Acute Lung Injury (CITRIS-ALI)

Sepsis | Acute Lung Injury

United States
Al Adan Hospital Kuwait

Completed

Effectiveness of Oral Immunotherapy Among Preterm Babies

Feeding Behavior | Late-Onset Neonatal Sepsis

Kuwait
Changi General Hospital
Genome Institute of Singapore, A*Star

Completed

The Association Between Microbiota, Endotoxaemia and the Host Obesity/ Insulin Resistance (MiPOOP Study) (MiPOOP)

Central Obesity

Singapore
Baxter Healthcare Corporation
Gambro Dialysatoren GmbH

Terminated

High Cut-Off Continuous Veno-venous Hemodialysis (CVVHD) in Patients Treated for Acute Renal Failure After Systemic Inflammatory Response Syndrome (SIRS)/Septic Shock (HICOSS)

Systemic Inflammatory Response Syndrome | Kidney Failure, Acute

Germany, Austria
MeMed Diagnostics Ltd.
European Commission

Completed

Prospective Study to Characterize Host-pathogen Related Factors in Hospitalized and ED Patients With LRTI and/or Sepsis (TailoredT)

Sepsis | Bacteremia | LRTI | Fungal Infections | Fever Without Source

Israel
Assistance Publique - Hôpitaux de Paris
Novartis

Terminated

Daptomycin Versus Vancomycin in the Treatment of Nosocomial or Healthcare-associated MRSA Bacteremia (DAVASAB)

Nosocomial Infection | Healthcare-associated Infection

France
Forest Laboratories

Completed

Safety and Efficacy Study of Ceftaroline in Subjects With Staphylococcus Aureus Bacteremia or With Persistent Methicillin-Resistant Staphylococcus Aureus Bacteremia

Staphylococcus Aureus Bacteremia | Methicillin-resistant Staphylococcus Aureus (MRSA) Bacteremia

United States
Emory University
Centers for Disease Control and Prevention; Sanofi Pasteur, a Sanofi Company

Completed

Yellow Fever Virus Vaccine and Immune Globulin Study

Viremia

United States
University Hospital, Bonn

Unknown

Surveillance for Nosocomial Infections in Pediatric Cancer Patients (Oncoped2006)

Invasive Aspergillosis | Bloodstream Infection | Nosocomial Infections

Switzerland
Asan Medical Center

Unknown

Early Continuous Renal Replacement Therapies (CRRT) in Patients With Severe Sepsis or Septic Shock With Acute Kidney Injury

Septic Shock | Acute Kidney Injury | Severe Sepsis

Korea, Republic of
Ruijin Hospital

Recruiting

The Impact of Coagulation Disorders on the Diagnosis and Prognosis of Sepsis

Sepsis | Coagulation Disorder

China
Odense University Hospital

Recruiting

Early Initiated Vasopressor Therapy in the Emergency Department (VASOSHOCK)

Shock | Shock, Septic | Hypotension | Hypovolemia | Hypotension and Shock | Hypovolemic Shock | Hypotension Symptomatic | Hypovolemic

Denmark
Azienda Ospedaliera Città della Salute e della...

Recruiting

Evaluation of Infective Risk, Efficacy of Bacterial Prophylaxis and Validation of Sepsis Scores NEWS (National Early Warning Score) and qSOFA (Quick Sequential Organ Failure Assessment) in Patient With Acute Myeloid Leukemia Treated With Intensive Chemotherapy (LAM-SEPSIS)

Acute Myeloid Leukemia

Italy
Armata Pharmaceuticals, Inc.
United States Department of Defense

Recruiting

Study Evaluating Safety, Tolerability, and Efficacy of Intravenous AP-SA02 in Subjects With S. Aureus Bacteremia (diSArm)

Bacteremia | Staphylococcus Aureus | Staphylococcus Aureus Bacteremia | Bacteremia Due to Staphylococcus Aureus | Bacteremia Staph

United States, Australia
Children's Hospital Medical Center, Cincinnati
University of Cincinnati; Cloudnine Hospital, Bangalore, India

Recruiting

Topical Coconut Oil Application and Incidence of Sepsis in Neonates

Late-Onset Neonatal Sepsis

India
Samsung Medical Center
Korea Health Industry Development Institute

Recruiting

Early Mobilization in Ventilated sEpsis & Acute Respiratory Failure Study (EVER)

Critically Ill | Early Mobility

Korea, Republic of
Radboud University Medical Center

Not yet recruiting

The Effects of Gut Micribiota Disruption on the Immune Response After Open Heart Surgery (REMEDI)

Coronary Artery Disease | Systemic Inflammatory Response Syndrome | Extracorporeal Circulation; Complications | Postoperative Shock

Netherlands
Medicines for Malaria Venture
GlaxoSmithKline; ICON plc; QIMR Berghofer Medical Research Institute; Swiss BioQuant... and other collaborators

Completed

Phase 1b MMV367 PK/PD and Safety in Healthy Adult Volunteers Experimentally Infected With Blood Stage P. Falciparum

Pathologic Processes | Infections | Systemic Inflammatory Response Syndrome | Inflammation | Vector Borne Diseases | Parasitic Diseases | Protozoan Infections | Malaria | Parasitemia | Malaria,Falciparum | Anti-Infective Agents | Antimalarials

Australia
University of Nebraska
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Terminated

Probiotics for Prevention Neonatal Infection

Sepsis | Neonatal Infections | Neonatal Sepsis

India
Assistance Publique - Hôpitaux de Paris

Completed

BetaLACTA® Test for Early De-escalation of Empirical Carbapenems in Pulmonary, Urinary and Bloodstream Infections in ICU (BLUE-CarbA)

Pneumonia | Urinary Tract Infections | Bloodstream Infection

France
Syndax Pharmaceuticals

Terminated

A Phase 2 Study to Evaluate Axatilimab for Hospitalized Participants With Respiratory Involvement Secondary to COVID-19

COVID | ARDS | Coronavirus | Cytokine Storm | Cytokine Release Syndrome

United States
Cubist Pharmaceuticals LLC

Completed

Daptomycin in the Treatment of Subjects With Infective Endocarditis or Bacteremia Due to S. Aureus

Bacteremia | Bacterial Endocarditis
Ono Pharmaceutical Co. Ltd

Completed

Study of Sivelestat Sodium Hydrate in Acute Lung Injury (ALI) Associated With Systemic Inflammatory Response Syndrome (SIRS) in Japan

Systemic Inflammatory Response Syndrome | Acute Lung Injury

Japan
Sygehus Lillebaelt
Kolding Sygehus

Completed

Neutrophil Gelatinase Associated Lipocalin (NGAL) in Urine: Can This Prove to be a Biomarker for Acute Kidney Injury in Patients With Sepsis?

Septic Shock | Acute Kidney Injury | Severe Sepsis

Denmark
East Carolina University

Terminated

Safety and Efficacy Study of Ethanol Locking to Prevent Central Line Infection in Premature Neonates

Sepsis | Bacteremia | Infection Associated With Catheter

United States
Northwestern University
National Cancer Institute (NCI)

Recruiting

CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors

Advanced Malignant Solid Neoplasm | Advanced Pancreatic Carcinoma | Metastatic Pancreatic Carcinoma | Refractory Pancreatic Carcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer... and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer

Peritoneal Carcinomatosis | Stage IV Uterine Corpus Cancer AJCC v8 | Stage IVA Uterine Corpus Cancer AJCC v8 | Stage IVB Uterine Corpus Cancer AJCC v8 | Metastatic Malignant Solid Neoplasm | Malignant Uterine Neoplasm | Clinical Stage IV Gastric Cancer AJCC v8 | Metastatic Colorectal Carcinoma | Stage... and other conditions

United States
Barbara Ann Karmanos Cancer Institute

Completed

Ask Questions (ASQ):Implementation of a Communication Intervention

Stage IV Lung Cancer | Stage III Bladder Cancer | Stage IV Bladder Cancer | Stage IV Breast Cancer | Stage II Breast Cancer | Stage II Prostate Cancer | Stage III Prostate Cancer | Stage IV Prostate Cancer | Stage III Breast Cancer | Stage IV Colorectal Cancer | Stage IV Ovarian Cancer | Stage III Lung Cancer | Stage III Cervical Cancer and other conditions

United States
National Cancer Institute (NCI)

Completed

MS-275 and Isotretinoin in Treating Patients With Metastatic or Advanced Solid Tumors or Lymphomas

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Peking University People's Hospital

Completed

Effect of NAC on the Hematopoietic Reconstitution After Haploidentical Hematopoietic Stem Cell Transplantation

Haploidentical Hematopoietic Stem Cell Transplantation

China
Chinese PLA General Hospital

Unknown

Mesenchymal Stem Cell Conditioned Medium-derived Pleiotropic Factor in Treating Residual Burn Wound

Mesenchymal Stem Cell-derived Pleiotropic Factor in Treating Residual Burn Wound

China
TC Erciyes University

Unknown

WHARTON JELLY ORIGINATED MESENCHIAL STEM CELL in GONARTHROSIS (WHAMKO)

Gonarthrosis | Stem Cell

Turkey
All India Institute of Medical Sciences, New Delhi
Indian Council of Medical Research

Unknown

Study of Homing of Labelled Stem Cells in Human Heart. (COLT)

Homing of Stem Cells in the Infarct Area.

India
Fate Therapeutics
Dana-Farber Cancer Institute

Completed

Safety and Efficacy of ProHema Modulated Umbilical Cord Blood Units in Subjects With Hematologic Malignancies.

Hematologic Malignancies | Allogeneic Stem Cell Transplantation

United States
Xencor, Inc.
ICON plc

Active, not recruiting

A Study of XmAb®23104 in Subjects With Selected Advanced Solid Tumors (DUET-3) (DUET-3)

Renal Cell Carcinoma | Nasopharyngeal Carcinoma | Small Cell Lung Cancer | Hepatocellular Carcinoma | Advanced Solid Tumors | Non-small Cell Lung Carcinoma | Squamous Cell Carcinoma of the Head and Neck | Cervical Carcinoma | Endometrial Carcinoma | Urothelial Carcinoma | Colorectal Carcinoma | Pancreatic Carcinoma and other conditions

United States
GOG Foundation
National Cancer Institute (NCI)

Active, not recruiting

Paclitaxel, Polyglutamate Paclitaxel, or Observation in Treating Patients With Stage III or Stage IV Ovarian Epithelial, Peritoneal Cancer, or Fallopian Tube Cancer

Ovarian Endometrioid Adenocarcinoma | Ovarian Seromucinous Carcinoma | Ovarian Undifferentiated Carcinoma | Ovarian Clear Cell Adenocarcinoma | Ovarian Mucinous Adenocarcinoma | Fallopian Tube Transitional Cell Carcinoma | Ovarian Transitional Cell Carcinoma | Fallopian Tube Clear Cell Adenocarcinoma and other conditions

United States
M.D. Anderson Cancer Center
Astex Pharmaceuticals, Inc.

Not yet recruiting

A Phase I/II Trial to Assess the Efficacy and Toxicity of ASTX727 (Oral Decitabine/Cedazuridine) for the Treatment of Hematological Neoplasms After Allogeneic Stem Cell Transplantation

Allogeneic Stem Cell Transplantation

United States
Nanfang Hospital of Southern Medical University
The Seventh Affiliated Hospital of Sun Yat-sen University; The First People... and other collaborators

Recruiting

Haplo-PBSC+Cord vs Haplo-PBSC+BM for Hematological Malignancies Undergoing Allo-HSCT

Hematopoietic Stem Cell Transplantation | Hematological Malignancies

China
Gadjah Mada University

Recruiting

Regeneration of Posterior Cruciate Ligament Injury Using Hypoxic Conditioned Allogenic Adipose Mesenchymal Stem Cell and Condition Medium

Ligament Rupture | Adypose Mesenchimal Stem Cell | Ligament Derived Conditined Medium

Indonesia
Shanghai General Hospital, Shanghai Jiao Tong University...
Changhai Hospital; Xiangya Hospital of Central South University; Tongji Hospital and other collaborators

Recruiting

CBA Versus FBA Conditioning Followed by Allogeneic HSCT in Treatment of High Risk and Refractory AML

High Risk Acute Myeloid Leukemia | Allogeneic Hematopoeitic Stem Cell Transplantation

China

Clinical Trials on Immune System Support

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Ukraine

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations