Clinical Trials on Immunologic Activity Alteration

Total 7432 results

Fundação Bahiana de Infectologia
GlaxoSmithKline

Completed

DTG Plus 3TC for Prophylaxis of Mother-to-child Transmission of HIV Infection in Pregnant Women (PREGNANCY)

HIV Infections | Pregnancy Related | Mother to Child Transmission

Brazil
ViiV Healthcare
GlaxoSmithKline; PPD

Completed

An Efficacy, Safety, and Tolerability Study Comparing Dolutegravir Plus Lamivudine With Dolutegravir Plus Tenofovir/Emtricitabine in Treatment naïve HIV Infected Subjects (Gemini 1)

HIV Infections | Infection, Human Immunodeficiency Virus

Taiwan, France, Germany, Belgium, United States, Canada, Netherlands, Spain, Korea, Republic of, Italy, Australia, United Kingdom, Russian Federation, Portugal, Argentina, South Africa, Romania, Mexico
Boston University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Boston ARCH 4F Intervention to Reduce Fall Risk in People With HIV and Alcohol Use

HIV Infection | Alcohol Consumption | Falls | Falls, Accidental

United States
University of California, San Francisco
National Institutes of Health (NIH); Fogarty International Center of the National...

Completed

Thermocoagulation for Treatment of Precancerous Cervical Lesions

HPV Infection | Human Immunodeficiency Virus | CIN 2/3

Kenya
BioCryst Pharmaceuticals

Completed

Study to Evaluate the Efficacy and Safety of BCX7353 as an Oral Treatment for the Prevention of HAE Attacks in Japan (APeX-J)

Hereditary Angioedema, HAE

Japan
Evandro Chagas National Institute of Infectious...
Valdiléa Veloso dos Santos, Ph.D.; Beatriz Grinzstejn, MD, PhD; Brenda Hoagland... and other collaborators

Completed

Seroincidence Study Among Men Who Have Sex With Men and Transgender Women - The ImPrEP Seroincidence Study (Seroincidence)

HIV Infections | Risk Behavior | HIV Seropositivity | Risk Reduction | STD | HIV Infection Primary | Risky Health Behavior

Brazil
University of California, Los Angeles

Completed

Cell Phone Technology Targeting ART and Naltrexone Adherence and Alcohol Use (ALCTXT)

HIV Infections | Alcohol Dependence

United States
Kirby Institute

Completed

Randomised Study of Interferon-free Treatment for Recently Acquired Hepatitis C in PWID and People With HIV Coinfection. (REACT)

Hepatitis C

Australia, United States, United Kingdom, New Zealand, Switzerland, Canada, Germany, Netherlands
Fundació Institut de Recerca de l'Hospital de la...
Fondo de Investigacion Sanitaria

Active, not recruiting

Immunophenotype of Risk in Older Patients Admitted for Pneumonia

Pneumonia | Frail Elderly Syndrome | Sarcopenia | Elderly Infection | Nutrition Disorders in Old Age | Age Associated Immune Deficiency

Spain
National Institute of Allergy and Infectious Diseases...
Bristol-Myers Squibb; Glaxo Wellcome

Completed

Comparison of 2',3'-Dideoxyinosine (Didanosine, ddI) and Zidovudine in Therapy of Patients With the AIDS Dementia Complex

HIV Infections | AIDS Dementia Complex

United States
Assistance Publique - Hôpitaux de Paris

Completed

Gene Therapy for X-linked Severe Combined Immunodeficiency (SCID2)

X-linked Severe Combined Immunodeficiency

France
University of Hawaii
ViiV Healthcare; University of Puerto Rico

Completed

Maraviroc and NeuroAIDS Pathogenesis

AIDS Dementia Complex

United States, Puerto Rico
Shire

Completed

Efficacy and Safety Study of DX-88 to Treat Acute Attacks of Hereditary Angioedema (HAE)

Hereditary Angioedema (HAE)

United States
Shire

Completed

Long-term Safety and Efficacy Study of DX-2930 (SHP643) to Prevent Acute Angioedema Attacks in Patients With Type I and Type II HAE

Hereditary Angioedema (HAE)

United States, United Kingdom, Germany, Canada, Italy, Jordan, Puerto Rico
Shire

Completed

Study to Evaluate the Clinical Efficacy and Safety of Subcutaneously Administered C1 Esterase Inhibitor for the Prevention of Angioedema Attacks in Adolescents and Adults With Hereditary Angioedema

Hereditary Angioedema (HAE)

Spain, Israel, United States, Hungary, Germany, Canada, Romania
Shire

Completed

CINRYZE for the Treatment of Hereditary Angioedema Attacks in Children Under the Age of 12

Hereditary Angioedema (HAE)

United States, Germany, Hungary
Shire

Completed

Subcutaneous CINRYZE With Recombinant Human Hyaluronidase for Prevention of Angioedema Attacks

Hereditary Angioedema (HAE)

United States, Germany, Spain, Sweden
Shire

Completed

Open-label, Single-arm Study to Assess the Pharmacokinetics, Safety, and Tolerability of a Single Subcutaneous Dose of Icatibant in Healthy Japanese Volunteers

Hereditary Angioedema (HAE)

United States
Shire

Completed

Safety and Efficacy Study of CINRYZE for Prevention of Angioedema Attacks in Children Ages 6-11 With Hereditary Angioedema

Hereditary Angioedema (HAE)

Israel, Germany, Mexico, United States, Romania
Shire

Completed

A Study of Icatibant for Acute Attacks of Hereditary Angioedema in Japanese Participants

Hereditary Angioedema (HAE)

Japan
Shire

Completed

A Double-Blind, Multiple Ascending Dose Study to Assess Safety, Tolerability and Pharmacokinetics of DX-2930 in Hereditary Angioedema Participants

Hereditary Angioedema (HAE)

United States, Jordan, Italy
BioCryst Pharmaceuticals

Completed

Efficacy and Safety of BCX7353 to Prevent Angioedema Attacks in Subjects With Hereditary Angioedema (APeX-1)

Hereditary Angioedema (HAE)

Canada, United Kingdom, Germany, Spain, Australia, Hungary, Italy, Austria, North Macedonia, Denmark, Switzerland
Federal Research Institute of Pediatric Hematology...

Completed

Romiplostim Treatment for Thrombocytopenia in Patients With Wiskott-Aldrich Syndrome.

Wiskott-Aldrich Syndrome

Russian Federation
Centre Hospitalier de Niort

Completed

Study on the Response to Tetanus Vaccination of People Living With HIV (VACTEVIH)

HIV Infections

France
ViiV Healthcare
GlaxoSmithKline

Completed

Effect of Rifabutin on the Pharmacokinetics of Oral Cabotegravir in Healthy Subjects

HIV Infections | Infection, Human Immunodeficiency Virus

United Kingdom
University Hospital, Strasbourg, France

Completed

Severe PID With Lymphoproliferation and Neutropenia (DICEP)

Primary Immune-Deficiency (PID) Common Variable Immune Deficiency (CVID)

France
National Human Genome Research Institute (NHGRI)

Withdrawn

Quality of Life and Neuropsychiatric Sequelae in Patients Treated With Gene Therapy for ADA-SCID and in Their Parents

ADA-SCID
The Immunobiological Technology Institute (Bio-Manguinhos)...
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Unknown

Validation of Rapid Tests for the Serological Diagnosis of HIV in 9 to 24 Months Old Children

Human Immunodeficiency Virus | Human Immunodeficiency Virus Transmission | Diagnoses, Syndromes, and Conditions

Brazil
Boston Medical Center
National Institute on Drug Abuse (NIDA); Emory University; Grady Health System

Completed

Targeting Effective Analgesia in Clinics for HIV - Patient Cohort (TEACH)

HIV Infection | Pain | Drug Dependence

United States
Boston Medical Center
National Institute on Drug Abuse (NIDA); Emory University; Grady Health System

Completed

Targeting Effective Analgesia in Clinics for HIV - Intervention (TEACH)

HIV Infection | Pain | Drug Dependence

United States
Albert Einstein College of Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Examining the Link Between Heart Disease and HIV Infection in Women

Cardiovascular Diseases | HIV Infections | Acquired Immunodeficiency Syndrome | Atherosclerosis
Janssen-Cilag International NV

Completed

A Clinical Trial Comparing the Efficacy of Darunavir/Ritonavir Monotherapy Versus a Triple Combination Therapy Containing Darunavir/Ritonavir and 2 Nucleoside/Nucleotide Reverse Transcriptase Inhibitors in Patients With Undetectable Plasma HIV-1 RNA on Current Treatment (PROTEA)

Human Immunodeficiency Virus (HIV) Infections | Acquired Immunodeficiency Syndrome (AIDS) Virus

France, United Kingdom, Belgium, Germany, Spain, Switzerland, Denmark, Israel, Austria, Poland, Hungary, Sweden, Ireland
Beau Nakamoto
National Institute of Neurological Disorders and Stroke (NINDS); University... and other collaborators

Completed

Ferumoxytol-enhanced Imaging and Mapping in neuroAIDS

AIDS Dementia Complex

United States
ViiV Healthcare
GlaxoSmithKline

Completed

Fractures Stratified by HIV and Antiretroviral Therapy (ART) Status

Infection, Human Immunodeficiency Virus | Fracture
ViiV Healthcare

Completed

GW640385 Plus Ritonavir And NRTIs For 48 Weeks In HIV-1 Infected Adults

HIV Infection | Infection, Human Immunodeficiency Virus I

United States
ViiV Healthcare

Terminated

GW873140 In Combination With Kaletra In HIV Infected Subjects

HIV Infection | Infection, Human Immunodeficiency Virus I

United States, Germany, France, Canada, Spain, Italy, Portugal, United Kingdom, Denmark, Netherlands
ViiV Healthcare

Completed

Observational Study Of A Protease Inhibitor (PI) Containing Regimen In Subjects With PI Mutations Selected During Prior Treatment With GW433908 (Fosamprenavir)

HIV Infection | Infection, Human Immunodeficiency Virus I

United States, Italy
GlaxoSmithKline

Completed

A Study Comparing The Safety, Tolerability and Efficacy of Trizivir VS Combivir & Atazanavir In Subjects With HIV

HIV Infection | Infection, Human Immunodeficiency Virus I

United States, Mexico
Stanley Jordan, MD
CSL Behring

Completed

Safety & Tolerability of Berinert® (C1 Inhibitor) Therapy to Prevent Rejection

Kidney Transplantation

United States
University of Delaware
National Institute on Drug Abuse (NIDA)

Completed

DVD-based HIV/HCV Prevention Intervention for Drug-Involved Latino Criminal Justice Clients

Acquired Immunodeficiency Syndrome | Hepatitis C | Human Immunodeficiency Virus

United States
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Exploring Novel Mechanisms of Vaccine Failure LAIV Pilot Study (LAIV)

Acquired Immune Deficiency Syndrome Virus

United Kingdom
National Heart, Lung, and Blood Institute (NHLBI)

Completed

AIDS-Associated Heart Disease -- Incidence and Etiology

Heart Diseases | HIV Infections | Acquired Immunodeficiency Syndrome | Myocardial Diseases
Dartmouth-Hitchcock Medical Center
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Investigational Vaccine for the Prevention of Disseminated Tuberculosis in HIV Infected People

HIV Infections | Tuberculosis

Tanzania
Columbia University
Centers for Disease Control and Prevention

Completed

Pediatric Enhanced Surveillance Study (PESS)

Human Immunodeficiency Virus (HIV) | Acquired Immune Deficiency Syndrome (AIDS)

South Africa
Janssen Pharmaceutica

Withdrawn

A Study on the Safety and Effectiveness of Rilpivirine Hydrochloride (Edurant) Among Adult Filipino Patients With Human Immunodeficiency Virus Type-I Infection

Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Columbia University
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Enhanced Prevention in Couples: Feasibility Study #2 (EPIC)

Human Immunodeficiency Virus (HIV) | Acquired Immune Deficiency Syndrome (AIDS)

Lesotho
Columbia University
National Institute of Mental Health (NIMH)

Completed

Multi-level Determinants of Starting ART Late: Aim 3 (LSTART)

Human Immunodeficiency Virus (HIV) | Acquired Immune Deficiency Syndrome (AIDS)

Ethiopia
Columbia University
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Enhanced HIV Prevention in Couples: Feasibility Study #3 (EPIC)

Human Immunodeficiency Virus (HIV) | Acquired Immune Deficiency Syndrome (AIDS)

Lesotho
EMD Serono

Completed

Growth Hormone in the Treatment of HIV-Associated Wasting

HIV Infections | HIV Wasting Syndrome
National Institute of Allergy and Infectious Diseases...

Completed

A Comparison of Two Caloric Supplements in the Prevention of Weight Loss in Patients With AIDS Who Take Daily Multivitamin and Mineral Supplements

HIV Infections | HIV Wasting Syndrome

United States

Clinical Trials on Immunologic Activity Alteration

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