Clinical Trials on Inborn Amino Acid Metabolism Disorder

Total 43860 results

Massachusetts Eye and Ear Infirmary
National Eye Institute (NEI)

Recruiting

Clinical Trial Comparing Two Non-Surgical Treatments for Severe Blepharoptosis

Stroke | Myasthenia Gravis | Traumatic Brain Injury | Chronic Progressive External Ophthalmoplegia | Ptosis, Eyelid | Blepharoptosis

United States
Diane George

Recruiting

CD34+ (Malignant) Stem Cell Selection for Patients Receiving Allogenic Stem Cell Transplant

Acute Lymphoblastic Leukemia (ALL) | Myelodysplastic Syndrome (MDS) | Acute Myelogenous Leukemia (AML) | Chronic Myeloid Leukemia (CML) | Juvenile Myelomonocytic Leukemia (JMML) | Lymphoma (Hodgkin's and Non-Hodgkin's)

United States
Universitätsklinikum Hamburg-Eppendorf
Charite University, Berlin, Germany; University Hospital Tuebingen; Technical... and other collaborators

Recruiting

Exercise and Nutrition Intervention in Ovarian Cancer (BENITA)

Fatigue | Malnutrition | Ovarian Cancer | Muscle Wasting

Germany
University of Chicago

Not yet recruiting

Study of Liraglutide (A Weight Loss Drug) in High Risk Obese Participants With Cognitive and Memory Issues

Multiple Sclerosis | Obesity | Obesity, Morbid | Obese | Long COVID | Long Covid19 | Acute Leukemia in Remission
Rutgers, The State University of New Jersey
National Cancer Institute (NCI)

Terminated

Medical Nutrition Therapy or Standard Care in Treating Patients With Lung Cancer, Pancreatic Cancer, or Stage III or Stage IV Prostate Cancer

Pancreatic Cancer | Malnutrition | Lung Cancer | Prostate Cancer | Weight Changes

United States
Case Western Reserve University

Completed

e-Mobile Tablet for People With Chronic Conditions

Multiple Sclerosis | Osteoarthritis | Parkinson's Disease | Fibromyalgia | Sjögren's Syndrome

United States
Theravance Biopharma

Completed

TD-9855 Phase 2 in Neurogenic Orthostatic Hypotension (nOH)

Parkinson Disease | Orthostatic Hypotension | Neurogenic Orthostatic Hypotension | Hypotension, Orthostatic | Pure Autonomic Failure | Multiple System Atrophy (MSA) With Orthostatic Hypotension | Pure Autonomic Failure With Orthostatic Hypotension | Parkinson Disease With Orthostatic Hypotension

United States
Peking University First Hospital

Recruiting

Semaglutide Improves Metabolic Abnormalities and Fertility in Obese Infertile Women With Polycystic Ovary Syndrome

Semaglutide | PCOS (Polycystic Ovary Syndrome)

China
University of Washington
National Cancer Institute (NCI)

Completed

Vitamin D Deficiency, Muscle Pain, Joint Pain, and Joint Stiffness in Postmenopausal Women Receiving Letrozole For Stage I-III Breast Cancer

Pain | Arthralgia | Stage I Breast Cancer | Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IIIC Breast Cancer | Recurrent Breast Cancer | Musculoskeletal Complications

United States
Assistance Publique - Hôpitaux de Paris
Institut National de la Santé Et de la Recherche Médicale, France

Completed

Validation of the Percentage of Alveolar Fibrocyte as Biomarker During ARDS (IFRA2)

Mechanical Ventilation | Acute Respiratory Distress Syndrome (ARDS)

France
Seattle Children's Hospital
Children's Hospital of Philadelphia

Not yet recruiting

Efficacy and Safety of Phentermine/Topiramate in Youth With Hypothalamic Obesity

Craniopharyngioma | Hypothalamic Obesity | Hypothalamic Tumor

United States
Universitas Sumatera Utara

Not yet recruiting

The Role of Thiamine After Transcatheter Closure in Children With Left-to-Right Shunt Congenital Heart Disease

Atrial Septal Defect | Congenital Heart Disease | Patent Ductus Arteriosus | Ventricular Septal Defect | Thiamine Deficiency

Indonesia
Danone Specialized Nutrition

Recruiting

Impact of a New Plant-based High-energy Oral Nutritional Supplement on Nutritional Outcomes in Malnourished Patients

Cancer | Inflammatory Bowel Diseases | Malnutrition | Hiv | Chronic Obstructive Pulmonary Disease (COPD)

Spain
Monash University
Novartis Pharmaceuticals

Recruiting

VICTORION-ASCERTAIN: Implementation Study (v-ASCERTAIN) (v-ASCERTAIN)

Cerebrovascular Disease | Coronary Heart Disease (CHD) | Peripheral Arterial Disease (PAD) | Atherosclerotic Cardiovascular Disease (ASCVD)

Australia
Muhimbili University of Health and Allied Sciences
GlaxoSmithKline

Recruiting

Effect of Adiposity and Associated Local Microbial Factors on Healing and Progression of Diabetic Foot Ulcers

Diabetic Foot Ulcer

Tanzania
University of Colorado, Denver

Completed

Post-Prandial Liver Glucose Metabolism in PCOS (PLUM)

Obesity | Polycystic Ovarian Syndrome | Hepatic Steatosis

United States
Boryung Pharmaceutical Co., Ltd

Completed

An Observation Study to Evaluate the Renoprotective Effect of Fimasartan in Patients With DKD and Proteinuria (FINALE)

Diabetic Kidney Disease | Proteinuria | Hypertension,Essential

Korea, Republic of
Prof. Dr. Jörg Leuppi

Completed

High Dose Vitamin-D Substitution in Patients With COVID-19: a Randomized Controlled, Multi Center Study (VitCov)

Covid19 | Vitamin D Deficiency | Corona Virus Infection | ARDS | SARS-CoV Infection | Coronavirus

Switzerland
King's College London
Imperial College London; University of Oxford; Sheffield Teaching Hospitals NHS...

Unknown

Pain In Neuropathy Study (PINS)

Chronic Pain | Carpal Tunnel Syndrome | Neuropathic Pain | Diabetic Neuropathy | Peripheral Neuropathies

United Kingdom
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of Avutometinib for People With Solid Tumor Cancers

Solid Tumor | Neuroblastoma | Solid Tumor, Adult | Primary Brain Tumor | Solid Carcinoma | Low-grade Glioma | Central Nervous System Tumor | Refractory Cancer | CNS Tumor, Adult | CNS Tumors | NF1 | Plexiform Neurofibroma | CNS Tumor, Childhood | Optic Pathway Gliomas | MAP Kinase Family Gene Mutation

United States
Eunice Kennedy Shriver National Institute of Child...

Completed

Defining the Genetic Basis for the Development of Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the Carney Complex

Pituitary Adenoma | Cushing's Syndrome | Carney Complex | Primary Pigmented Nodular Adrenocortical Disease | Peutz-Jeghers Syndrome

United States
National Cancer Institute (NCI)

Completed

Veliparib in Treating Patients With Malignant Solid Tumors That Do Not Respond to Previous Therapy

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Breast Carcinoma | Ovarian Carcinoma | Pancreatic Carcinoma | Prostate Carcinoma | Recurrent Breast Carcinoma | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative... and other conditions

United States
Roswell Park Cancer Institute

Completed

Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Primary Myelofibrosis | Polycythemia Vera | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma and other conditions

United States
Ilya Pharma
European Commission

Recruiting

Evaluating Safety and Biological Effect on Wound Healing of ILP100-Topical in Subjects With Diabetic Foot Ulcers

Diabetic Foot Ulcer | Wound Heal | Wound Healing Disorder | Wound Healing Delayed | Wound Healing Disturbance of | Diabetic Foot Ulcer Mixed

Sweden
Department of Nephrology Clinic Ottakring Vienna

Recruiting

Treating Patients With Renal Impairment and Altered Glucose MetAbolism With TherapeutIc Carbohydrate Restriction and Sglt2-Inhibiton - a Pilot Study

Diabetes Mellitus | Chronic Kidney Diseases | PreDiabetes | Overweight and Obesity

Austria
Murdoch Childrens Research Institute
National Health and Medical Research Council, Australia; Royal Children's Hospital and other collaborators

Recruiting

Generation Victoria Cohort 2020s: A Statewide Longitudinal Cohort Study of Victorian Children and Their Parents (GenV)

Communicable Diseases | Quality of Life | Inflammation | Obesity | Congenital Abnormalities | Genetics | Healthy Aging | Child Development | Diet | Mental Health | Disability | Injuries | Cognition | Child Health | Environmental Exposure | Noncommunicable Diseases | Physical Fitness | Intergenerational Relations | Social Determinants... and other conditions

Australia
Sun Pharma Advanced Research Company Limited

Completed

Study of Doxorubicin in Patients With Metastatic Breast Cancer/Advanced Ovarian Cancer

Breast Cancer and Ovarian Cancer
Central Hospital, Nancy, France

Completed

Obesity and Mortality of Critically Ill Patients With COVID-19 (COV-OB-ICU)

Severe Acute Respiratory Syndrome | Obesity | COVID | Comorbidities and Coexisting Conditions

France
Zealand University Hospital

Completed

Vitamin D Treatment of Diabetic Patients With Foot Ulcers

Diabetic Foot Ulcers | Vitamin D Deficiency
University of Alabama at Birmingham
Children's Health System, Alabama

Completed

Vitamin D Supplementation for Extremely Preterm Infants

Vitamin D Deficiency | Preterm Infants | Bronchopulmonary Dysplasia

United States
National Taipei University of Nursing and Health...
Tri-Service General Hospital

Not yet recruiting

Study on the Effect of Incentive Spirometer-based Respiratory Training on the Long COVID-19

Hypertension | Diabetes | Long COVID | Cardiac Disease | COVID-19 Pandemic
Theravance Biopharma

Recruiting

Phase 3 Efficacy and Durability of Ampreloxetine for the Treatment of Symptomatic nOH in Participants With Multiple System Atrophy (CYPRESS)

MSA - Multiple System Atrophy | Symptomatic Neurogenic Orthostatic Hypotension

United States, Spain, United Kingdom, Hungary, Italy, Argentina, Austria, Poland, Germany, Portugal, Belgium, Brazil, Denmark, Canada, France, Chile, Estonia
Shanghai Gynecologic Oncology Group
Fudan University

Not yet recruiting

Survival Effect of Hepato-celiac Lymphadenectomy In Primary or Relapsed Ovarian Cancer

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Carcinoma

China
Edith Nourse Rogers Memorial Veterans Hospital
Biomedical Advanced Research and Development Authority; AIDAR Health, Inc.

Active, not recruiting

Using Data From a Multisensor Rapid Health Assessment Device to Predict Decompensation in Long COVID (AIDI) (AIDI)

COVID-19 | Long COVID

United States
University of Nebraska
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Vascular Risk After Kidney Transplantation

Cardiovascular Disease | Diabetes | Hyperparathyroidism | Vitamin D Deficiency | Chronic Kidney Disease

United States
The Cleveland Clinic

Active, not recruiting

A Prospective Study Frailty for Esophagectomy and Lung Resection in Thoracic Surgery

Malnutrition | Esophageal Cancer | Lung Cancer | Frail Elderly Syndrome | Sarcopenia | Surgery | Surgery--Complications | Thoracic Neoplasm | Thoracic

United States
Queen Mary University of London

Completed

Skeletal Muscle Wasting and Renal Dysfunction After Critical Illness Trauma - Outcomes Study (KRATOS)

Quality of Life | Critical Illness | Chronic Kidney Diseases | Acute Kidney Injury | Muscle Loss | Major Trauma

United Kingdom
OPKO Health, Inc.

Active, not recruiting

Safety, Efficacy, PK and PD of CTAP101 (Calcifediol) ER Capsules for SHPT in HD Patients VDI

Chronic Kidney Diseases | Vitamin D Deficiency | Stage 5 Chronic Kidney Disease | Secondary Hyperparathyroidism Due to Renal Causes

United States
Chen-Yu Chen
I-Shou University

Completed

Hyperbaric Oxygen Therapy in Diabetics With Chronic Foot Ulcers and Improvement of Quality of Life

Diabetes | Diabetic Foot Ulcer
Children's Hospital and Health System Foundation...
University of Wisconsin, Madison

Completed

Coping Skills Training (CST) for Children With Chronic Health Conditions

Epilepsy | Asthma | Spina Bifida | Rheumatologic Conditions (JRA,Lupus)

United States
UMC Utrecht
Johns Hopkins University

Recruiting

Investigation on the Cortical Communication System (CortiCom)

Neuromuscular Diseases | Traumatic Brain Injury | Locked-in Syndrome | Brainstem Stroke

Netherlands
Brigham and Women's Hospital
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

Nurses' Health Study (Cardiovascular Component)

Myocardial Infarction | Heart Diseases | Cardiovascular Diseases | Coronary Disease | Diabetes Mellitus | Angina Pectoris | Menopause | Cerebrovascular Accident | Pulmonary Embolism | Postmenopause
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Surgery in Preventing Ovarian Cancer in Patients With Genetic Mutations

Hereditary Breast and Ovarian Cancer Syndrome | Premenopausal | Deleterious BARD1 Gene Mutation | Deleterious BRCA1 Gene Mutation | Deleterious BRCA2 Gene Mutation | Deleterious BRIP1 Gene Mutation | Deleterious EPCAM Gene Mutation | Deleterious MLH1 Gene Mutation | Deleterious MSH2 Gene Mutation | Deleterious... and other conditions

United States
University of Nebraska

Recruiting

Integrated Cancer Repository for Cancer Research (iCaRe2)

Melanoma | Sarcoma | Kidney Cancer | Leukemia | Breast Cancer | Laryngeal Cancer | Hypopharyngeal Cancer | Nasopharyngeal Cancer | Multiple Myeloma | Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Small Intestine Cancer | Ovarian Cancer | Lynch Syndrome | Lung Cancer | Rectal Cancer | Prostate Cancer | Gastrointestinal... and other conditions

United States
Complejo Hospitalario Universitario de Albacete
University of Warwick; University Hospitals Coventry and Warwickshire NHS Trust and other collaborators

Not yet recruiting

An Integrated Solution for Sustainable Care for Multimorbid Elderly Patients With Dementia (CAREPATH)

Behavioral Symptoms | Coronary Artery Disease | Heart Failure | Stroke | Hypertension | Diabetes | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Malnutrition | Asthma | Dementia | Alzheimer Disease | Frailty | Sarcopenia | Comorbidities and Coexisting Conditions

Spain
University of Miami

Recruiting

Clinical Applications of Advanced Ophthalmic Imaging

Multiple Sclerosis | Diabetic Retinopathy | Dementia | Dry Eye Syndromes | Presbyopia | Myopia

United States
Tufts University
M.D. Anderson Cancer Center; Fox Chase Cancer Center; Ohio State University; Tufts...

Active, not recruiting

NutriCare Plus a Medically Tailored Meal Intervention Among Patients With Lung Cancer

Lung Cancer Metastatic | Lung Cancer, Non-small Cell | Treatment Side Effects | Lung Cancer, Small Cell | Lung Cancer Recurrent | Nutritional Imbalance

United States
Chelsea Therapeutics

Completed

Open-Label Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH) (NOH303)

Multiple System Atrophy | Neurogenic Orthostatic Hypotension | Dopamine Beta Hydroxylase Deficiency | Non-Diabetic Autonomic Neuropathy

United States, Australia, Canada, New Zealand
Assistance Publique - Hôpitaux de Paris
Iltoo Pharma

Completed

Induction of Regulatory t Cells by Low Dose il2 in Autoimmune and Inflammatory Diseases (TRANSREG)

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Psoriasis | Systemic Sclerosis | Crohn's Disease | Ulcerative Colitis | Idiopathic Thrombocytopenic Purpura | Autoimmune Hepatitis | Wegener's Granulomatosis | Ankylosing Spondylitis | Behcet's Disease | Takayasu's Disease | Sclerosing Cholangitis | Gougerot-sj...

France
AeRang Kim

Active, not recruiting

MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors

Osteosarcoma | Ewing Sarcoma | Neuroblastoma | Rhabdomyosarcoma | Wilms Tumor | Desmoid Tumor | Germ Cell Tumor | Relapsed Pediatric Solid Tumors | Refractory Pediatric Solid Tumors | Hepatic Tumor

United States

Clinical Trials on Inborn Amino Acid Metabolism Disorder

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Portugal

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations