Clinical Trials on Infective Endocarditis in United States

Total 4686 results

Lysovant

Withdrawn

ERAdicate S. Aureus in Patients With Bacteremia and Endocarditis (ERASE)

Endocarditis Infective | Bacteremia Due to Staphylococcus Aureus | Left Sided Infective Endocarditis (Disorder) | Right Sided Infective Endocarditis (Disorder)

United States
Virginia Commonwealth University

Withdrawn

Retrospective Review of Management of Infective Endocarditis

Endocarditis

United States
Cubist Pharmaceuticals LLC

Terminated

Phase 4 Efficacy and Safety Study of Cubicin® With and Without Combination Therapy in S. Aureus Infective Endocarditis (SAIE)

Infective Endocarditis

United States
University of Edinburgh

Unknown

PET/MR Imaging In Patients With Infective Endocarditis

Infective Endocarditis

United Kingdom
AbbVie

Terminated

Efficacy and Safety of Dalbavancin Compared to Standard of Care Antibiotic Therapy for the Completion of Treatment of Patients With Complicated Bacteremia or Infective Endocarditis

Bacteremia | Endocarditis

United States
Queen Mary University of London
Barts & The London NHS Trust; Quadram Institute Bioscience

Recruiting

Accuracy of Metagenomic Blood Sampling to Identify Pathogen in Infective Endocarditis Patients (AMetIP)

Infective Endocarditis

United Kingdom
Cubist Pharmaceuticals LLC

Terminated

Phase 2 Study of Safety, Efficacy, and Pharmacokinetics of Higher Doses of Daptomycin and Vancomycin in MRSA Bacteremia (HDSAB)

Infective Endocarditis | Endocarditis, Bacterial

United States
Wake Forest University Health Sciences

Recruiting

Reducing Risk for Infective Endocarditis (PIE-B)

Bacteremia | Infective Endocarditis

United States
University of Rochester

Completed

Cardiac Surgery Peer Recovery Support Program

Substance Use Disorders | Infective Endocarditis | IV Drug Usage

United States
ContraFect

Terminated

Direct Lysis of Staph Aureus Resistant Pathogen Trial of Exebacase (DISRUPT)

Staphylococcus Aureus Bacteremia | Staphylococcus Aureus Endocarditis

United States
University of Pennsylvania

Withdrawn

Oritavancin for Staphylococcus Aureus Infections in Opioid Users

Staphylococcus Aureus Bacteremia | Staphylococcus Aureus Endocarditis

United States
Centre Chirurgical Marie Lannelongue

Completed

Infective Endocarditis in Percutaneous Pulmonary Revalvulation: Comparison Between Melody and Sapien Valves (Endopulm)

Congenital Heart Disease | Infective Endocarditis | Percutaneous Pulmonary Valve Implantation

France, Germany, Italy, Portugal, Saudi Arabia, Spain, United Kingdom
Weill Medical College of Cornell University

Terminated

Daptomycin as an Adjuvant Agent in the Treatment of Enterococcal Native Valve Endocarditis.

Endocarditis, Bacterial

United States
ContraFect

No longer available

Expanded Access Study of Exebacase in COVID-19 Patients With Persistent MRSA Bacteremia

Covid19 | MRSA Bacteremia | MRSA Bloodstream Infection | MRSA Right-sided Endocarditis

United States
Laura Fanucchi

Completed

Combining Opioid Addiction Treatment Services With CARe for Infectious Endocarditis (CATS-CARE)

Endocarditis, Bacterial | Opioid-use Disorder | Outpatient Parenteral Antibiotic Therapy | Buprenorphine

United States
Emory University

Completed

Outcomes Following Medical or Surgical Management of Endocarditis

Endocarditis

United States
William Beaumont Hospitals

Terminated

Cardiac Computed Tomography (CT) Scan Compared to Transesophageal Echocardiogram (TEE) in Endocarditis

Endocarditis

United States
Abbott Medical Devices
University of Pittsburgh

Terminated

Artificial Valve Endocarditis Reduction Trial (AVERT)

Aortic Valve Disease | Endocarditis | Mitral Valve Disease

United States, Canada, Spain, Netherlands, Switzerland, France, Germany, Italy
ContraFect

Completed

Safety, Efficacy and Pharmacokinetics of CF-301 vs. Placebo in Addition to Antibacterial Therapy for Treatment of S. Aureus Bacteremia

Staphylococcus Aureus Bacteremia | Staphylococcus Aureus Endocarditis

United States, Belgium, Bulgaria, Chile, Czechia, France, Germany, Greece, Guatemala, Israel, Italy, Russian Federation, Spain, United Kingdom
Vinay Badhwar

Enrolling by invitation

Postoperative Antibiotic Management Duration Following Surgery for Intravenous Drug Abuse (IVDA) Endocarditis (OPTIMAL) (OPTIMAL)

Endocarditis

United States
Stony Brook University
The Plastic Surgery Foundation

Completed

Postoperative Antibiotic Requirements Following Immediate Breast Reconstruction

Breast Implantation | Bacterial Infection | Anti-infective Agents

United States
Washington University School of Medicine
Centers for Disease Control and Prevention

Completed

Probiotics to Promote Intestinal Health

Communicable Diseases | Infection | Therapeutic Uses | Anti-Infective Agents | Pharmacologic Actions

United States
Henry Ford Health System

Terminated

Safety and Efficacy of Strategy to Prevent Drug-Induced Nephrotoxicity in High-Risk Patients (STOP-NT)

Bacteremia | Endocarditis | Acute Bacterial Skin and Skin Structure Infections | Health Care Associated Pneumonia | Osteomyelitis/Septic Arthritis

United States
University of Hull

Recruiting

PREhabilitation in Patients Awaiting Acute Inpatient Cardiac SurgEry ((PREP-ACE))

Coronary Artery Disease | Aortic Valve Disease | Endocarditis | Cardiac Disease | Valve Heart Disease

United Kingdom
Beth Israel Deaconess Medical Center

Completed

The Digital Incentive Spirometer (DIS): Improving Adherence to Incentive Spirometry (DIS)

Pulmonary Atelectasis | Adherence, Patient | Post-Op Complication | Incentive Spirometry | Post-Op Infection

United States
University of Pennsylvania

Completed

How v. How and Why Nudges and Rewards

Control Condition | How Incentive Receive | How Incentive Holdout | How Incentive Ineligible | How and Why Incentive Receive | How and Why Incentive Holdout | How and Why Incentive Ineligible

United States
Infectopharm Arzneimittel GmbH
INPADS GmbH; Dr. Oestreich + Partner GmbH

Recruiting

Fosfomycin i.v. for Treatment of Severely Infected Patients (FORTRESS)

Respiratory Tract Infections | Sepsis | Encephalitis | Bacterial Infections | Intraabdominal Infections | Bacteremia | Skin Diseases, Bacterial | Pneumonia, Bacterial | Urinary Tract Infections | Meningitis, Bacterial | Central Nervous System Bacterial Infections | Soft Tissue Infections | Endocarditis, Bacterial | Bone Diseases, Infectious and other conditions

Germany, Austria, Greece, Italy, United Kingdom
Ondine Biomedical Inc.

Completed

Red Light Photobiomodulation and Topical Disinfectants

Surgical Site Infection | Nosocomial Infection | Healthcare Associated Infection

United States
West Virginia University

Enrolling by invitation

Comparing Oral Versus Parenteral Antimicrobial Therapy (COPAT)

Skin and Soft Tissue Infection | Gastrointestinal Infection | Pulmonary Infection | Bone and Joint Infection | Endovascular Infection | Genitourinary Infection

United States
Ondine Biomedical Inc.

Completed

Nasal Photodisinfection in All Patients Presenting for Surgery for a Wide Range of Surgical Procedures (BENEFIT-PDT)

Nosocomial Infection | Surgical Site Infections | Healthcare Associated Infections

United States
Angela Bianco
Stryker Nordic

Terminated

Preoperative Application of Chlorhexidine to Reduce Infection With Cesarean Section After Labor (PRACTICAL)

Cesarean Section | Surgical Site Infection | Nosocomial Infection

United States
Yaneve Fonge

Recruiting

Aqueous vs Alcohol Chlorhexidine Skin Preparation for Prevention of Cesarean Section Wound Infections

Surgical Site Infection | Cesarean Section; Infection

United States
Columbia University

Completed

Vaginal Preparation With Chlorhexidine-alcohol vs. Povidine-iodine vs. Saline

Surgical Site Infection | Cesarean Section; Infection

United States
Abington Memorial Hospital

Unknown

Abdominal Closure Bundle to Reduce Surgical Site Infection in Patients Undergoing C-sections. Cesarean Section Lead to Reduction in Surgical Site Infection? - A Randomized Controlled Trial

Surgical Site Infection | Cesarean Section; Infection

United States
Gundersen Lutheran Medical Foundation
Gundersen Lutheran Health System

Completed

Clipping Versus No Hair Removal and the Risk of Surgical Site Infections

Surgical Site Infection | Superficial Surgical Site Infection | Deep Surgical Site Infection | Organ/Space Surgical Site Infection

United States
The Cleveland Clinic

Completed

Prevena™ Incisional Negative Pressure Wound Therapy in Re-operative Colorectal Surgery

Surgical Site Infection

United States
AlloVir

Withdrawn

Most Closely Human Leukocyte Antigen (HLA)-Matched BK Virus-specific T Lymphocytes (Viralym-B)

BK Virus Infection

United States
Duke University
Agency for Healthcare Research and Quality (AHRQ)

Completed

Early Recognition and Response to Increases in Surgical Site Infections Using Optimized Statistical Process Control Charts: The Early 2RIS Study (Early 2RIS)

Surgical Site Infection | Infection Control

United States
Children's Healthcare of Atlanta

Withdrawn

Wick vs. No Wick: Does Method of Closure Affect Rate of Wound Infection?

Postoperative Wound Infection

United States
Sean Devitt

Recruiting

Studying How Outpatient Water affEcts Risks With Drains (SHOWER Study) (SHOWER)

Postoperative Complications | Surgical Site Infection | Drain Site Complication | Postoperative Wound Infection

United States
Major Extremity Trauma Research Consortium
United States Department of Defense

Recruiting

Topical Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures at High Risk of Infection: TOBRA

Post Operative Surgical Site Infection

United States
The University of Texas Medical Branch, Galveston

Recruiting

Antibacterial-coated Sutures at Time of Cesarean (ASTC)

Cesarean Section Complications | Surgical Wound Infection | Surgical Site Infection | Cesarean Section; Infection

United States
University of Iowa
Professional Disposables International, Inc.

Completed

Nasal Decolonization for Orthopedic Trauma Patients

Surgical Site Infection

United States
3M
Sharp HealthCare

Terminated

Impact of Pre-surgical Nasal Bacterial Reduction on Postoperative Surgical Site Infections / Standard Care Change

Surgical Site Infection

United States
Major Extremity Trauma Research Consortium

Completed

Local Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures at High Risk of Infection: A Multicenter Randomized, Controlled Trial (VANCO) (VANCO)

Post Operative Surgical Site Infection

United States
Washington University School of Medicine

Terminated

Dose Escalation Trial of Intrasite Vancomycin Pharmacokinetics

Surgical Site Infection

United States
Eastern Virginia Medical School
Cupron Inc.

Completed

Effect of Copper Impregnated Textiles on Healthcare Associated Infections and Antibiotic Use

Hospital Acquired Infection

United States
AdventHealth

Recruiting

Reducing Wound Infections Using Bioelectric Wound Dressings (JumpStart)

Surgical Site Infection

United States
Vanderbilt University

Completed

Use of 2% Chlorhexidine Cloths Reduce Surgical Site Infections

Surgical Site Infection

United States
Nimbic Systems, LLC
Baylor College of Medicine; National Institute of General Medical Sciences...

Completed

Air Barrier System for the Prevention of Surgical Site Infection (ABS)

Surgical Site Infection

United States

Clinical Trials on Infective Endocarditis in United States

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