Clinical Trials on International Classification of Diseases / Standards in South Africa

Total 794 results

Prisma Health-Upstate
National Institute on Drug Abuse (NIDA); Clemson University

Recruiting

An Integrated Intervention Involving Recovery Coaching and Cognitive Behavioral Therapy for Opioid Use Disorder (OVERCOME 2)

Standard of Care | Standard of Care + CBT4CBT | Standard of Care + CBT4CBT + RC

United States
Harriet Shezi Children's Clinic

Unknown

Dosing, Safety and Pharmacokinetic Profile of Rifabutin in Children Receiving Concomitant Treatment With Kaletra (RBT)

Children With Confirmed HIV Infection | Receiving ART Regimen Containing 2 NRTIs + LPV/RTV at Standard Dose | Successfully Completed TB Treatment in the Past 2 to 6 Weeks of Enrollment

South Africa
Medical University of South Carolina
Johns Hopkins University; University of North Carolina; Cook Endoscopy; Thoraxklinik-Heidelberg...

Completed

22-gauge ProCore Needle v. Standard 22-gauge (P00030500)

Quantity of Tissue Obtained | Quality of Tissue Obtained | Ease of Use of 22-gauge ProCore EBUS Needles and the Standard 22-gauge Needles

United States
AstraZeneca

Completed

Centralized Pan-South African Survey on the Undertreatment of Hypercholesterolaemia (CEPHEUS)

Undertreatment of Hypercholesterolaemia

South Africa
Brown University

Completed

Schools Championing Safe South Africa

Prevention or Reduction of HIV Risk Behavior | Prevention or Reduction of Intimate Partner Violence

South Africa
Cycle Pharmaceuticals Ltd.
Parexel

Completed

Assessment of Intra-subject Variability in the Bioavailability of Chlorpromazine Hydrochloride

Acute Intermittent Porphyria | Anti-Psychotic | Management of Manifestations of Psychotic Disorders | Treatment of Schizophrenia | Control Nausea and Vomiting | Relief of Restlessness and Apprehension Before Surgery | Adjunct in the Treatment of Tetanus | Control Manifestations of the Manic Type... and other conditions

South Africa
University of KwaZulu
University of California, San Francisco; Centers for Disease Control and Prevention and other collaborators

Completed

Effectiveness of an HIV-adapted IMCI Training and Supervision Programme for Community Health Workers

Infant Feeding Practices | Prevention of Mother-to-child Transmission of HIV | Antenatal Health Care Utilization | Postnatal Health Care Utilization

South Africa
University of Johannesburg

Completed

The Efficacy of Venavine Intensive® on the Quality of Life in Females With Chronic Venous Insufficiency

Venous Insufficiency

South Africa
Helen Joseph Hospital
University of Johannesburg; Abbott Point of Care; Lodox Systems (Ltd)

Completed

Early Point-Of-Care Blood Tests, ECG & X-rays in the Emergency Department (EPOC-BEX-ED)

Emergency Medicine | Point-of-Care Testing

South Africa
University of Cape Town
Karolinska Institutet

Completed

Use of Low Sensitivity Pregnancy Test for Self-assessment of Medical Abortion (m-Assist+)

Completion of Medical Abortion

South Africa
DePuy International

Terminated

A Single Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Primary Hip Resurfacing Surgery

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Nonunion of Femoral Fractures

South Africa
University of the Western Cape

Completed

Interventions for Patients With a Shortened Dental Arch (SDA-RCT)

Anomaly of Dental Arch

South Africa
Novartis

Completed

A Quality of Life and Safety Study With Pimecrolimus Cream, 1% in Children (Age 2-12 Years) With Atopic Dermatitis

Atopic Eczema

South Africa
University of Cape Town

Unknown

Self-expandable Metal Stents Versus Multiple Plastic Stents for Palliation of Biliary Obstruction

Biliary Stricture | Cancer of the Pancreas | Bile Duct Obstruction, Extrahepatic | Cancer of the Bile Duct

South Africa
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

Drug-drug Interaction Study With MDV3100 and a Cocktail of Substrates

Castration Resistant Prostate Cancer (CRPC) | Pharmacokinetics of MDV3100

South Africa
Eastern Virginia Medical School
Gilead Sciences; United States Agency for International Development (USAID); FHI... and other collaborators

Active, not recruiting

Project Engage: Oral PrEP Acceptability

Adherence, Medication | Acceptability of Health Care

South Africa, Zimbabwe
Duke University
The Emmes Company, LLC

Recruiting

Pharmacokinetics of Antiretroviral Drugs in Lactating Women and Breastmilk Fed Infants Under 6 Months of Age in Botswana (BMS02)

HIV Infections | Lactating Women on Select DOI | Breastmilk Fed Infants of Mothers on Select DOI

South Africa
H. Lee Moffitt Cancer Center and Research Institute
Merck Sharp & Dohme LLC

Completed

Preparedness Study - HPV Vaccine

Sexual Transmission of Infection

United States, South Africa
University of Cape Town
King's College London; University of KwaZulu

Completed

Collaborative Care for the Detection and Management of Depression Among Adults Receiving Antiretroviral Therapy in South Africa (COBALT)

Depression | HIV/AIDS | Chronic Diseases of Lifestyle

South Africa
University of Maryland, College Park
National Institute on Drug Abuse (NIDA); Medical Research Council, South Africa

Active, not recruiting

Siyakhana Peer: Evaluating a Peer Recovery Coach Model to Reduce Substance Use Stigma in South African HIV Care

Substance-Related Disorders | HIV | Substance Use | Substance Use Disorders | Treatment Adherence | Treatment Adherence and Compliance | Stigmatization | Delivery of Health Care | Stigma, Social | Attitude of Health Personnel | Community Health Workers | Health Personnel | Health Personnel Attitude | Health Care Seeking... and other conditions

South Africa
University of Cape Town

Completed

Iron Deficiency Anaemia in Pregnant Patients Presenting for Antenatal Care

Iron Deficiency Anemia of Pregnancy

South Africa
Antiva Biosciences

Completed

Study of Topical ABI-1968 in Subjects With Precancerous Cervical Lesions From Human Papillomavirus (HPV) Infection.

Cervical Cancer | Human Papilloma Virus | HSIL, High Grade Squamous Intraepithelial Lesions | Cervical Dysplasia | HSIL of Cervix | High-Grade Cervical Intraepithelial Neoplasia | HIV Negative | CIN - Cervical Intraepithelial Neoplasia | Cervical Neoplasm

South Africa
Arthrex, Inc.

Recruiting

Evaluate the Continued Safety and Performance of the Foot and Ankle Products

Hyperpronated Foot | Reconstruction Surgeries of the Foot | Fixation of Fractures and Fusion (Bunionectomy Osteotomies) of the Foot/Ankle | Fixation of Small Bone Fragments of the Foot/Ankle | Lisfranc Arthrodesis | Mono or Bi-cortical Osteotomies in the Forefoot | First Metatarsophalangeal Arthrodesis and other conditions

Germany, United States, South Africa
University of Maryland, College Park
National Institute of Mental Health (NIMH); Medical Research Council, South...

Completed

Community Health Worker Training to Reduce Depression and Substance Use Stigma in TB/HIV Care in South Africa (Siyakhana)

Substance-Related Disorders | Depression | Tuberculosis | Hiv | Mental Health Disorder | Mental Disorder | Health Care Utilization | Treatment Adherence and Compliance | Social Stigma | Attitude of Health Personnel | Community Health Workers | Health Care Delivery

South Africa
Novartis Pharmaceuticals

Completed

Re-treatment of Participants With Paget's Disease Using Zoledronic Acid

Paget's Disease of the Bone

Spain, Canada, New Zealand, Belgium, South Africa, United Kingdom
Faculty of Medicine

Completed

Uterotonic Efficacy of Oxytocin 2.5 Versus 10 Units During Caesarean Section at Mulago Hospital

Uterine Hemorrhage | Adverse Effect of Oxytocic Drugs | Inappropriate Dose of Drug Administered

Uganda
International Atomic Energy Agency

Unknown

Clinical and Experimental Studies to Improve Radiotherapy Outcome in AIDS Cancer Patients

Cancer of the Cervix

India, South Africa, Tanzania, Uganda, Zimbabwe
Horizon Health Network
University of Manitoba; University of British Columbia; University of Michigan; Dalhousie University and other collaborators

Completed

Sonography in Hypotension and Cardiac Arrest in the Emergency Department. (SHoC-ED)

Shock | Hypotension | Point of Care Ultrasound

Canada, South Africa
University College, London
M.D. Anderson Cancer Center; National Cancer Institute (NCI); National Institutes... and other collaborators

Recruiting

ARCHERY - Artificial Intelligence Based Radiotherapy Treatment Planning for Cervical, Head and Neck and Prostate Cancer

Cancer Head Neck | Cancer of Prostate | Cancer Cervix

India, Jordan, Malaysia, South Africa
National Cancer Institute (NCI)

Recruiting

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8

United States, Puerto Rico, Canada
University of Cape Town

Completed

Study of Hip and Knee Arthroplasty in South Africa

Arthritis, Rheumatoid | Osteoarthritis, Knee | Osteoarthritis, Hip | Arthritis Knee | Arthritis of Hip

South Africa
Cosmetique Active International

Recruiting

Effect of Lipikar Baume AP+M on Quality of Life and Pain of Adults With Dryness or Severe Xerosis

Skin Diseases | Atopic Dermatitis

Croatia, Germany, Portugal, South Africa, Taiwan, Thailand, Vietnam
AIDS Malignancy Consortium
National Cancer Institute (NCI); University of California, Los Angeles; Merck... and other collaborators

Active, not recruiting

HPV Vaccine Therapy in Reducing High-Grade Cervical Lesions in Patients With HIV and HPV (COVENANT)

HIV Infection | AIDS-Related Human Papillomavirus Infection | High Grade Cervical Squamous Intraepithelial Neoplasia

Uganda, Kenya, Zimbabwe, South Africa, Malawi
University of Miami
National Institute of Neurological Disorders and Stroke (NINDS); National Institutes...

Recruiting

Phenotype, Genotype and Biomarkers 2 (PGB2)

Amyotrophic Lateral Sclerosis | Primary Lateral Sclerosis | Frontotemporal Dementia | Progressive Muscular Atrophy | Hereditary Spastic Paraplegia

United States, South Africa
Medical University of South Carolina

Completed

Evaluation of the Duration of Bupivacaine Spinal Block in Orthopedic Procedures With and Without Epinephrine Wash

Arthropathy of Knee | Arthropathy of Hip

United States
Foundation for Innovative New Diagnostics, Switzerland
Swiss Tropical & Public Health Institute; University of Cape Town; The HIV Netherlands... and other collaborators

Completed

FujiLAM Prospective Evaluation Trial

Diagnosis of Tuberculosis in People Living With HIV

Malawi, South Africa, Tanzania, Thailand, Uganda, Vietnam, Zambia
University of Vermont

Completed

Mobile Technology to Support Physical Therapy Exercise (MyTherEx)

Osteoarthritis of Knee | Osteoarthritis Of Hip

United States
Hellenic Breast Surgeons Society

Completed

Impact of Chemotherapy Followed by Aromatase Inhibitors on Bone Health of Women With ER-positive Early Breast Cancer (POCHARBI)

Breast Cancer | Other Disorders of Bone Density and Structure

Greece
Novartis Pharmaceuticals

Completed

Safety and Efficacy Trial With Zoledronic Acid for the Treatment of Paget's Disease of Bone, Including an Extended Observation Period

Paget's Disease of Bone

United States, Germany, Spain, United Kingdom, Canada, France, Belgium, South Africa, Australia, New Zealand
Wollo University

Recruiting

Interactive Mobile Health Intervention to Improve Early Postpartum Modern Contraceptive Method Uptake (EPPMC)

Other Cardiovascular Diseases of Mother, Postpartum

Ethiopia
AstraZeneca

Completed

A Pharmacokinetic (PK) and Pharmacodynamic (PD) Dose-ranging Phase II Study of Ticagrelor in Paediatric Patients With Sickle Cell Disease (HESTIA 1)

Investigation of Platelet Aggregation in Paediatric Patients With Sickle Cell Disease

United States, Canada, United Kingdom, South Africa, Lebanon, Kenya
Agricultural University of Athens

Completed

Determining the Glycemic Effects of Sunflower Pasta

Appetitive Behavior | Potential Abnormality of Glucose Tolerance

Greece
Agricultural University of Athens

Completed

Characterizing Emmer Seeds and Flours, and Determining the Glycemic Effects of Emmer Breads

Appetitive Behavior | Potential Abnormality of Glucose Tolerance

Greece
Agricultural University of Athens

Completed

Effects of Sugar-free Products With Added Sweeteners on Glycemic Responses

Appetitive Behavior | Potential Abnormality of Glucose Tolerance

Greece
Agricultural University of Athens

Completed

Effects of Traditional Greek Meals on Glycemic Responses

Appetitive Behavior | Potential Abnormality of Glucose Tolerance

Greece
Agricultural University of Athens

Completed

Acute Effects of Fruit Juices Consumption on Postprandial Glycemic Responses and Satiety

Appetitive Behavior | Potential Abnormality of Glucose Tolerance

Greece
Agricultural University of Athens

Completed

Acute Effects of Spirulina on Postprandial Glycemic Responses and Arterial Blood Pressure

Blood Pressure | Appetitive Behavior | Potential Abnormality of Glucose Tolerance

Greece
Agricultural University of Athens

Completed

Acute Effect of Crocus Sativus on Postprandial Glycemia

Blood Pressure | Appetitive Behavior | Potential Abnormality of Glucose Tolerance

Greece
InGeneron, Inc.
Sanford Health

Recruiting

Safety of Adipose-derived Regenerative Cells Injection for Treatment of Osteoarthritis of the Facet Joint

Osteoarthritis of Facet Joint of Lumbar Spine

United States
Medical University of South Carolina

Completed

Compare Epidural vs. Lumbar Plexus Analgesia After Hip Arthroplasty

Arthropathy of Hip

United States

Clinical Trials on International Classification of Diseases / Standards in South Africa

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