Clinical Trials on Kynurenine Pathway and Its Metabolites

Total 602 results

Novartis

Completed

Efficacy of Tegaserod in Relieving the Symptoms of Female Patients With Irritable Bowel Syndrome (IBS), Excluding Those With Predominant Diarrhea IBS

IBS-C and IBS With Mixed Bowel Habits
Erik Mittra
National Cancer Institute (NCI)

Terminated

18F-FDOPA PET/CT or PET/MRI in Measuring Tumors in Patients With Newly-Diagnosed or Recurrent Gliomas

Untreated Childhood Brain Stem Glioma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Oligodendroglioma | Adult Pilocytic Astrocytoma | Adult Pineal Gland Astrocytoma and other conditions

United States
Hamad Medical Corporation

Unknown

Effect of Taurine on Glycemic Control in Type I and Type II Diabetic Patients

it is a Group of Metabolic Diseases in | Which a Person Has High Blood Sugar, Either | Because the Body Does Not Produce Enough Insulin, | or Because Cells do Not Respond to the Insulin That | is Produced.
National Cancer Institute (NCI)

Completed

Low-Dose or High-Dose Lenalidomide in Treating Younger Patients With Recurrent, Refractory, or Progressive Pilocytic Astrocytoma or Optic Pathway Glioma

Neurofibromatosis Type 1 | Recurrent Childhood Pilocytic Astrocytoma | Recurrent Childhood Visual Pathway Glioma

United States, Canada, Australia, New Zealand
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Psychosocial Support for African-American, Latina-American, or European-American Cervical Cancer Survivors

Cervical Cancer | Cancer Survivor | Psychosocial Effects of Cancer and Its Treatment

United States
Centre Leon Berard
Ministry of Health, France

Terminated

Study of Vismodegib in Combination With Temozolomide Versus Temozolomide Alone in Patients With Medulloblastomas With an Activation of the Sonic Hedgehog Pathway

Histologically Confirmed Medulloblastoma | Activation of the Sonic Hedgehog (SHH) Pathway

France, Italy, Switzerland, United Kingdom
University Hospital Schleswig-Holstein

Withdrawn

Confocal Laser Endomicroscopy in IBS Patients

Food Intolerance | IBS

Germany
Southwest Oncology Group
National Cancer Institute (NCI); Cancer and Leukemia Group B

Completed

SWOG-9208 Quality of Life and Health Status in Patients With Stage I or Stage II Hodgkin's Disease

Lymphoma | Psychosocial Effects of Cancer and Its Treatment

United States
Institut Bergonié

Completed

Psychological and Social Factors That May Increase the Risk of Developing Chronic Pain After Surgery in Women With Breast Cancer

Pain | Breast Cancer | Psychosocial Effects of Cancer and Its Treatment
M.D. Anderson Cancer Center

Not yet recruiting

Phase I/II Study of a Combination of Decitabine and Cedazuridine (ASTX727) and ASTX029, an ERK Inhibitor, for Patients With RAS Pathway Mutant Myelodysplastic Syndromes and Myelodysplastic/Myeloproliferative Neoplasms

Myeloproliferative Neoplasm | Myelodysplastic Neoplasm | Pathway Mutant Myelodysplastic Syndromes

United States
Kyle Staller, MD, MPH
Ardelyx

Recruiting

Effect of Tenapanor on the Metagenomics and Metabolomics of Patients With Irritable Bowel Syndrome With Constipation

IBS - Irritable Bowel Syndrome | IBS

United States
University of Michigan
National Institute of Neurological Disorders and Stroke (NINDS); National Institutes... and other collaborators

Completed

Optimization of Transcutaneous Electrical Acustimulation (TEA) Modalities for Treatment of IBS-C (TEA)

Constipation | IBS

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Making Decisions About Participating in a Cancer Clinical Trial for Patients With Stage II, Stage III, or Stage IV Pancreatic Cancer or Stage III or Stage IV Colon Cancer or Rectal Cancer

Colorectal Cancer | Pancreatic Cancer | Psychosocial Effects of Cancer and Its Treatment

United States
Gruppo Italiano Malattie EMatologiche dell'Adulto

Not yet recruiting

Real World Evaluation of the Activity and Safety of Fostamatinib in Consecutive Adult Patients With ITP

ITP - Immune Thrombocytopenia | Chronic ITP | Refractory ITP
Nutrabiotix, LLC
Rush University Medical Center

Terminated

Use of Novel Prebiotic Fiber for Targeted Dietary Management of Irritable Bowel Syndrome (Nutrabiotix Phase II)

Constipation-predominant IBS (IBS-C)

United States
University of Miami
National Eye Institute (NEI)

Completed

BCI and Evaluation of Visual and Task Performance in Subjects With Eye Diseases

Glaucoma | Macular Degeneration | Retinal Degeneration | Optic Neuropathy | Glaucoma Suspect | Visual Pathway Disorder

United States
European Organisation for Research and Treatment...
ETOP IBCSG Partners Foundation; German Adjuvant Breast Cancer Group

Completed

Assessing Women's Attitudes About the Risk of Infertility Related to Adjuvant Therapy for Early Breast Cancer

Breast Cancer | Psychosocial Effects of Cancer and Its Treatment | Sexuality and Reproductive Issues | Sexual Dysfunction and Infertility

Belgium, Switzerland, Peru, Italy, Germany, Netherlands, United Kingdom, Serbia, Chile, Poland, Croatia, Turkey, South Africa, Lebanon, Portugal
University of California, Irvine
National Cancer Institute (NCI)

Completed

Telephone Counseling or Standard Care in Patients Who Have Completed Treatment for Stages I, II, or III Cervical Cancer

Cervical Cancer | Psychosocial Effects of Cancer and Its Treatment

United States
UNICANCER

Completed

Doxorubicin and Cyclophosphamide in Treating Older Women With Stage I, Stage II, or Stage III Breast Cancer That Has Been Removed By Surgery

Depression | Breast Cancer | Malnutrition | Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment

France
Greater Boston Medical Associates
Massachusetts General Hospital

Unknown

Experience With H.P. Acthar Gel Treatment of Patients With Nephrotic Syndrome/Proteinuria Due to Various Etiologies and Its Effect on Podocyte Function (Acthar)

Decrease of Proteinuria With H.P. Acthar Gel and Its Effects on Clinical and Podocyte Function

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI); Fox Chase Cancer Center

Completed

Couples Therapy to Enhance Intimacy Between Patients With Advanced or Recurrent Prostate Cancer and Their Partners

Sexual Dysfunction | Prostate Cancer | Psychosocial Effects of Cancer and Its Treatment | Sexuality and Reproductive Issues

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Completed

Aerobic Exercise, Resistance Exercise, or Flexibility and Relaxation Training in Inactive Older Female Breast Cancer Survivors

Breast Cancer | Fatigue | Cancer Survivor | Psychosocial Effects of Cancer and Its Treatment | Long-term Effects Secondary to Cancer Therapy in Adults

United States
NYU Langone Health
Bayer Healthcare Pharmaceuticals, Inc./Bayer Schering Pharma

Terminated

Sorafenib in Children and Young Adults With Recurrent or Progressive Low-Grade Astrocytomas

neurofibromatosis1 (NF1) | Recurrent or Progressive Optic Pathway Gliomas (OPG) | Recurrent or Progressive Low-grade Glioma

United States
Tel-Aviv Sourasky Medical Center

Completed

Probiotic in Irritable Bowel Syndrome (IBS) Patients With Diarrhea (IBS-D)

IBS

Israel
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Quality of Life in Female Breast Cancer Survivors and Their Spouse, Partner, or Acquaintance

Breast Cancer | Cancer Survivor | Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment | Sexuality and Reproductive Issues | Spiritual Concerns

United States
Mayo Clinic
National Cancer Institute (NCI)

Withdrawn

Nicotine in Treating "Hunger Pain" in Patients With Malignant Bowel Obstruction Caused By Cancer

Pain | Anorexia | Unspecified Adult Solid Tumor, Protocol Specific | Psychosocial Effects of Cancer and Its Treatment | Constipation, Impaction, and Bowel Obstruction
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Healing Touch in Treating Patients Receiving Chemotherapy for Acute Myeloid Leukemia or Acute Lymphocytic Leukemia

Leukemia | Fatigue | Psychosocial Effects of Cancer and Its Treatment

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Unknown

Communication and Intimacy-Enhancing Therapy for Men With Early Stage Prostate Cancer and Their Partners

Prostate Cancer | Psychosocial Effects of Cancer and Its Treatment | Sexuality and Reproductive Issues | Sexual Dysfunction and Infertility

United States
Cairo University

Unknown

The Prevalence of Extra Root Canals and the Root Canal Configuration in Mandibular Anterior Teeth in a Sample of Egyptian Population Using Cone Beam Computed Tomography

Number of Root Canals and it's Configurations in Lower Anteriors
Assiut University

Unknown

The Role of Lung Ultrasound in The Diagnosis of Weaning -Induced Pulmonary Edema

Detecting the Number of B-lines in Lung Ultrasound and Its Accuracy in Diagnosis of Weaning Induced Pulmonary Oedema
Leap of Faith Technologies
National Cancer Institute (NCI)

Completed

Study of @neWorld: A Virtual Community for Children With Cancer

Lymphoma | Unspecified Childhood Solid Tumor, Protocol Specific | Leukemia | Psychosocial Effects of Cancer and Its Treatment

United States
Beth Israel Deaconess Medical Center

Terminated

Dose Ranging Study With the Probiotic Combination (VSL#3) in Diarrhea IBS

IBS

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Mindful Movement Program in Improving Quality of Life in Older Female Breast Cancer Survivors

Depression | Breast Cancer | Cancer Survivor | Cognitive/Functional Effects | Anxiety Disorder | Psychosocial Effects of Cancer and Its Treatment

United States
The First Affiliated Hospital of Soochow University
Shanghai Unicar-Therapy Bio-medicine Technology Co.,Ltd

Recruiting

Anti-BCMA CAR T-Cell Therapy for R/R ITP

ITP

China
Peking University People's Hospital
Beijing Hospital

Recruiting

Gut Microbiota in ITP

ITP

China
Helwan University

Completed

The Incidence of Gall Stones After Bariatric Surgery and Its Association With Weight Loss

The Incidence of Gall Stones After Bariatric Surgery and Its Association With Weight Loss

Egypt
Vanderbilt University Medical Center

Completed

Vertical Expandable Prosthetic Titanium Rib (VEPTR) for Thoracic Insufficiency Syndrome (VEPTR)

Thoracic Insufficiency Syndrome (TIS)

United States
Danone Research

Completed

A Single-centre, Randomised, Double-blind, Controlled, Parallel-group Study to Evaluate the Effect of a Fermented Dairy Product on Abdominal Distension, Digestive Symptoms and Rectal Sensitivity in Patients With Irritable Bowel Syndrome With Constipation (IBS-C)

Women With IBS-C

United Kingdom
Gregory A. Dekaban
University of Western Ontario, Canada; Ontario Institute for Cancer Research

Unknown

Tracking Peripheral Blood Mononuclear Cells With Fluorine MRI (TRACK)

Adverse Reaction to Diagnostic Agents and Kits Nos

Canada
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Withdrawn

Probiotic Therapy in Preventing Gastrointestinal Complications in Patients Undergoing Chemotherapy and Pelvic Radiation Therapy

Fatigue | Diarrhea | Unspecified Adult Solid Tumor, Protocol Specific | Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment | Gastrointestinal Complications | Constipation, Impaction, and Bowel Obstruction
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Physical Activity or Usual Care in Preventing Weight Gain in Women With Stage I or Stage II Breast Cancer Undergoing Chemotherapy

Depression | Breast Cancer | Fatigue | Psychosocial Effects of Cancer and Its Treatment | Weight Changes

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI); University College, London; McMaster University and other collaborators

Completed

Measuring Patient Satisfaction With Facial Appearance: Development and Validation of a New Patient-Reported Outcome Measure

Head and Neck Cancer | Psychosocial Effects of Cancer and Its Treatment

United States, Canada, United Kingdom
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Individualized Exercise Programs for Patients Receiving Chemotherapy for Newly Diagnosed Acute or Relapsed Myeloid Leukemia or Lymphoblastic Leukemia

Depression | Leukemia | Fatigue | Psychosocial Effects of Cancer and Its Treatment | Musculoskeletal Complications

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Educational and Skills Training Program for Parents of Childhood Cancer Survivors Who Have Neurobehavioral Dysfunction

Lymphoma | Leukemia | Cancer Survivor | Cognitive/Functional Effects | Long-term Effects Secondary to Cancer Therapy in Children | Psychosocial Effects of Cancer and Its Treatment

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Study of Physical and Mental Health of Older Patients With Newly Diagnosed Cancer

Depression | Pain | Malnutrition | Unspecified Adult Solid Tumor, Protocol Specific | Hematopoietic/Lymphoid Cancer | Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment | Weight Changes

United States
University of Dundee

Completed

Investigating Hereditary Cardiac Disease by Reprogramming Skin Cells to Heart Muscle (CLUE)

Eletrophysiology of iPS-derived Cardiomyocytes

United Kingdom
Assiut University

Completed

First rTMS for Treatment of Drug Induced Tardive Syndromes. Double Randomized Clinical Trial

Drug Induced Tardive Syndrome (DITS)

Egypt
Hacettepe University

Not yet recruiting

Adaptation of Mattresses Made With Different Materials to Personal Anthropometry Values and Body Postures

Sleep Disorder | Pressure Ulcer | Spine Degeneration | Body Structure, Altered From Its Original Anatomical Structure
University of Arizona
National Cancer Institute (NCI)

Completed

Moderate Physical Activity in Helping Patients Recover Physically and Emotionally From Stage II Or Stage III Colorectal Cancer

Depression | Colorectal Cancer | Anxiety Disorder | Psychosocial Effects of Cancer and Its Treatment

United States
Assiut University

Not yet recruiting

IL37,Tlymphocytes,NK Cells in Pathogenesis of ITP

ITP

Clinical Trials on Kynurenine Pathway and Its Metabolites

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CROs in South Korea

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