Clinical Trials on Leukemia, B-Cell, Chronic

Total 7848 results

Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Fludarabine and Busulfan Followed by Donor Peripheral Stem Cell Transplant and Antithymocyte Globulin, Tacrolimus, and Methotrexate in Treating Patients With Myeloid Cancer

Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Myelodysplastic/Myeloproliferative Diseases | Graft Versus Host Disease

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy and Antithymocyte Globulin in Reducing Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplantation For Myelodysplastic Syndrome or Myeloproliferative Disorder

Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Myelodysplastic/Myeloproliferative Diseases | Graft Versus Host Disease

United States
Tufts Medical Center
National Cancer Institute (NCI)

Completed

A Web-Based Stem Cell Transplant Support System or Standard Care in Young Patients Undergoing Stem Cell Transplant and Their Families

Sarcoma | Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Ovarian Cancer | Neuroblastoma | Psychosocial Effects of Cancer and Its Treatment | Myelodysplastic/Myeloproliferative Neoplasms

United States
RemeGen Co., Ltd.

Recruiting

A RC198 Study in Subjects With Locally Advanced Unresectable or Metastatic Solid Tumors

Melanoma | Renal Cell Carcinoma | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Urothelial Carcinoma | Colorectal Carcinoma

Australia, China
Janux Therapeutics

Recruiting

Study of JANX008 in Subjects With Advanced or Metastatic Solid Tumor Malignancies

Renal Cell Carcinoma | Non-Small Cell Lung Cancer | Squamous Cell Carcinoma of the Head and Neck | Colorectal Carcinoma

United States
National Cancer Institute (NCI)

Completed

Vaccine Therapy in Treating Patients With Colon, Pancreatic, or Lung Cancer

Recurrent Pancreatic Cancer | Stage III Pancreatic Cancer | Extensive Stage Small Cell Lung Cancer | Recurrent Colon Cancer | Recurrent Rectal Cancer | Stage II Pancreatic Cancer | Stage IVA Pancreatic Cancer | Stage IVB Pancreatic Cancer | Stage I Pancreatic Cancer | Stage II Non-small Cell Lung Cancer | Stage III Colon Cancer and other conditions

United States
Sanguine Biosciences

Completed

At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions

Depression | Melanoma | Epilepsy | Lymphoma | Multiple Sclerosis | Kidney Cancer | Cervical Cancer | Diabetes Mellitus | Leukemia | Breast Cancer | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Parkinson's Disease | Systemic Lupus Erythematosus | Multiple Myeloma | Hepatitis B | Insomnia | Colorectal Cancer | HIV/AID... and other conditions

United States
Tehran University of Medical Sciences

Completed

Evaluate the Safety and Feasibility of Allogeneic Mesenchymal Stem Cells in Patients With Multiple Sclerosis (MS)

Multiple Sclerosis | Mesenchymal Stem Cells | Secondary-Progressive Multiple Sclerosis

Iran, Islamic Republic of
Dana-Farber Cancer Institute
National Cancer Institute (NCI); Prometheus Laboratories; Miltenyi Biomedicine...

Active, not recruiting

Trial of Regulatory T-cells Plus Low-Dose Interleukin-2 for Steroid-Refractory Chronic Graft-versus-Host-Disease

Chronic Graft Versus Host Disease | Chronic GVHD | Complications of Organ Transplant Stem Cells

United States
National Cancer Institute (NCI)

Terminated

Pilot Trial of Targeted Immune-Depleting Chemotherapy and Reduced-Intensity Matched Unrelated Double Cord Blood Transplant for the Treatment of Leukemias, Lymphomas, and Pre-Malignant Blood Disorders

Leukemia | Multiple Myeloma | MDS | Non-Hodgkins Lymphoma | Hodgkins Lymphoma

United States
Massachusetts General Hospital
Dana-Farber Cancer Institute

Terminated

Non-Myeloablative HLA-Mismatched Ex-Vivo T-cell Depleted Stem Cell Transplantation for Hematologic Malignancies

Lymphoma | Leukemia | Multiple Myeloma | Myelodysplastic Syndrome

United States
University of Southern California

Terminated

Pegylated Liposomal Doxorubicin (Doxil) With Rituximab in Relapsed AIDS-Related Non-Hodgkin's Lymphomas

Non-Hodgkin's Lymphoma | Burkitt Lymphoma | Primary Effusion Lymphomas

United States
Fate Therapeutics

Completed

FATE-NK100 as Monotherapy and in Combination With Monoclonal Antibody in Subjects With Advanced Solid Tumors

Melanoma | Renal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Cancer | Pancreatic Cancer | Non Small Cell Lung Cancer | Advanced Solid Tumors | HER2-positive Breast Cancer | Head and Neck Squamous Cell Carcinoma | HER2 Positive Gastric Cancer | EGFR Positive Solid Tumor

United States
Leiden University Medical Center
Erasmus Medical Center; Amsterdam UMC, location VUmc

Recruiting

Allogeneic MSC Treatment for Pulmonary Emphysema

Pulmonary Emphysema | Mesenchymal Stromal Cells

Netherlands
Mitchell Cairo

Recruiting

AlloSCT for Malignant and Non-malignant Hematologic Diseases Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletion

Hodgkin Lymphoma | Sickle Cell Disease | Acute Leukemia | Beta-Thalassemia | Non-hodgkin Lymphoma | Severe Aplastic Anemia | Diamond Blackfan Anemia | Amegakaryocytic Thrombocytopenia | Kostmann

United States
Massachusetts General Hospital

Completed

Combined Bone Marrow Transplantation (BMT) and Renal Transplant for Multiple Myeloma (MM) With End Stage Renal Disease (ESRD)

Multiple Myeloma | End Stage Renal Disease

United States
Novartis Pharmaceuticals

Recruiting

Platform Study of JDQ443 in Combinations in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation (KontRASt-03)

Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Colorectal Cancer | Non-Small Cell Lung Cancer | Nonsmall Cell Lung Cancer | Carcinoma, Non-Small Cell Lung | Colorectal Tumors | Colorectal Carcinoma | Neoplasms, Colorectal | Non-Small Cell Lung Carcinoma | KRAS G12C Mutant Solid Tumors

Korea, Republic of, Spain, Belgium, United States, France, Germany, Italy, Singapore
Cellerant Therapeutics
Department of Health and Human Services

Completed

Safety Study of Human Myeloid Progenitor Cells (CLT-008) After Cord Blood Transplant for Hematologic Malignancy

Lymphoma | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma | Plasma Cell Neoplasm

United States
Paul G. Kemps, MD
Juliana Children's Hospital

Active, not recruiting

GastroIntestinal Cancer in Children and Adolescents (GICCA)

Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Burkitt Lymphoma | Neuroendocrine Tumors | Gastrointestinal Cancer | Hepatoblastoma

Netherlands
National Cancer Institute (NCI)

Completed

Flavopiridol in Treating Children With Relapsed or Refractory Solid Tumors or Lymphomas

Unspecified Childhood Solid Tumor, Protocol Specific | Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Recurrent Neuroblastoma | Recurrent Osteosarcoma | Recurrent Childhood Rhabdomyosarcoma | Recurrent Wilms Tumor and Other Childhood Kidney Tumors | Recurrent Childhood Soft... and other conditions

United States
National Cancer Institute (NCI)

Completed

Lenalidomide and Cetuximab in Treating Patients With Advanced Colorectal Cancer or Head and Neck Cancer (ADCC)

Recurrent Colon Carcinoma | Recurrent Rectal Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Stage IV Hypopharyngeal Squamous Cell Carcinoma AJCC v7 | Stage IVA Laryngeal Squamous Cell... and other conditions

United States
European Organisation for Research and Treatment...

Completed

Prevention of Infection in Patients With Hematologic Cancer and Persistent Fever Caused by a Low White Blood Cell Count

Lymphoma | Unspecified Childhood Solid Tumor, Protocol Specific | Myelodysplastic Syndromes | Leukemia | Unspecified Adult Solid Tumor, Protocol Specific | Infection | Multiple Myeloma and Plasma Cell Neoplasm | Fever, Sweats, and Hot Flashes | Bone Marrow Suppression

Switzerland, United States, Canada, United Kingdom, Belgium, Israel, Slovakia, Finland, Germany, France, Turkey, Czech Republic, Greece
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Doxorubicin Hydrochloride Liposome and Bortezomib in Treating Patients With Refractory Hematologic Cancer or Malignant Solid Tumor or Metastatic Breast Cancer

Lymphoma | Leukemia | Breast Cancer | Ovarian Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm

United States
Kahr Medical

Recruiting

A Study of DSP107 Alone and in Combination With Atezolizumab for Patients With Advanced Solid Tumors

Colorectal Cancer | Non Small Cell Lung Cancer | Advanced Solid Tumor

United States
Janssen Research & Development, LLC

Completed

First-in-Human Study of JNJ-74699157 in Participants With Tumors Harboring the KRAS G12C Mutation

Neoplasms | Colorectal Cancer | Advanced Solid Tumors | Non-small Cell Lung Cancer

France, United States
National Cancer Institute (NCI)

Completed

Feasibility and Preliminary Efficacy of a Mindfulness-based Intervention for Children and Young Adults With High Grade or High-Risk Cancer and Their Caregivers

Sarcoma | Leukemia | Astrocytoma | Brain Cancer | Glioblastomas

United States
Bellicum Pharmaceuticals

Active, not recruiting

Study of Gene Modified Donor T Cell Infusion in Patients With Recurrent Disease After Allogeneic Transplant

Lymphoma | Myelodysplastic Syndromes | Leukemia | Hematologic Neoplasms | Multiple Myeloma

United States
Massachusetts General Hospital
Dana-Farber Cancer Institute

Terminated

Non-Myeloablative HLA-Matched Ex-Vivo T-cell Depleted Stem Cell Transplantation for Hematologic Malignancies

Lymphoma | Leukemia | Multiple Myeloma | Myelodysplastic Syndrome

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
M.D. Anderson Cancer Center; Fred Hutchinson Cancer Center; Otsuka Pharmaceutical...

Completed

Allo BMT Using Matched Related/Unrelated Donors With FluBu and HiCY

Lymphoma | Leukemia | Multiple Myeloma | Myelodysplastic Syndrome

United States
Copenhagen University Hospital at Herlev

Completed

Can Treatment With Bismuth Reduce Toxicity to Chemotherapy and Radiotherapy? (Bismuth-PBH)

Leukemia | Multiple Myeloma | Hematological Malignancies | Hematological Diseases | Blood Diseases | Malignant Lymphoma

Denmark
Washington University School of Medicine

Completed

Study of Hypotensive Hematopoietic Malignancy Patients' USCOM Readings

Lymphoma | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma | Paraproteinemias

United States
Mayo Clinic

Recruiting

Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program

Malignant Solid Neoplasm | Renal Cell Carcinoma | Hepatocellular Carcinoma | Metastatic Cutaneous Melanoma | Unresectable Cutaneous Melanoma | Lung Non-Small Cell Carcinoma | Urothelial Carcinoma | Stage III Renal Cell Cancer AJCC v8 | Stage IV Renal Cell Cancer AJCC v8 | Recurrent Head and Neck Squamous... and other conditions

United States
University Hospital, Basel, Switzerland

Unknown

Hematopoietic Stem Cell Therapy in Chronic Wounds Using a Pressure Sore Model

Wound Healing | Chronic Wounds | Hematopoietic Stem Cells | Pressure Sores

Switzerland
University of Arizona
National Cancer Institute (NCI)

Terminated

Pentostatin and Alemtuzumab as a Preparative Regimen for Allogeneic Peripheral Blood Stem Cell Transplantation

Lymphoma | Carcinoma, Renal Cell | Leukemia | Hematologic Neoplasms | Multiple Myeloma | Hodgkin's Disease

United States
GlaxoSmithKline

Terminated

Eltrombopag To Reduce The Need For Platelet Transfusion In Subjects With Chronic Liver Disease And Thrombocytopenia Undergoing Elective Invasive Procedures (ELEVATE)

Liver Diseases | HIV Infection | Thrombocytopenia | Hepatitis C Virus | HBV | NASH - Nonalcoholic Steatohepatitis | Human Immunodeficiency Virus | Chronic Liver Disease | HCV | Non-alcoholic Steatohepatitis | Hepatitis B Virus

United States, Spain, Taiwan, Italy, Belgium, France, Korea, Republic of, Canada, Russian Federation, Pakistan, Poland, India, Argentina
MedImmune LLC

Completed

A Multiple Ascending Dose Study of MEDI7247 in Advanced or Metastatic Solid Tumors

Metastatic Castration-resistant Prostate Cancer (mCRPC) | Small Cell Lung Cancer (SCLC) | Pancreatic Ductal Adenocarcinoma (PDAC) | Head and Neck Squamous Cell Carcinoma (HNSCC) | Colorectal Cancer (CRC) | Non Small Cell Lung Cancer Squamous (NSCLC-Sq)

United States, Canada
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Laboratory-Treated Donor Bone Marrow in Treating Patients Who Are Undergoing a Donor Bone Marrow Transplant for Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases | Graft Versus Host Disease

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Suberoylanilide Hydroxamic Acid in Treating Patients With Advanced Solid Tumors That Have Not Responded to Previous Therapy

Lymphoma | Leukemia | Small Intestine Cancer | Prostate Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm

United States
Nutricia Research

Recruiting

Effect of an Oral Nutritional Supplement on Muscle Mass During Anticancer Treatment (ALLIES)

Non-small Cell Lung Cancer (NSCLC) | Colorectal Cancer (CRC)

Ireland
Stanford University

Completed

Allogeneic Transplantation From Related Haploidentical Donors

Leukemia | MDS | NHL | Graft Versus Host Disease | Blood Cancer | Malignancy | CLL | Hodgkin's Disease

United States
National Cancer Institute (NCI)

Terminated

Phase I Study of Cetuximab With RO4929097 in Metastatic Colorectal Cancer

Recurrent Colon Carcinoma | Recurrent Rectal Carcinoma | Stage IVA Colon Cancer | Stage IVA Rectal Cancer | Stage IVB Colon Cancer | Stage IVB Rectal Cancer | Colon Mucinous Adenocarcinoma | Colon Signet Ring Cell Adenocarcinoma | Rectal Mucinous Adenocarcinoma | Rectal Signet Ring Cell Adenocarcinoma

United States
Seagen Inc.

Recruiting

A Study of SGN-EGFRd2 in Advanced Solid Tumors

Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Squamous Cell Carcinoma of the Head and Neck | Pancreatic Ductal Adenocarcinoma

United States
Amgen

Completed

Study of the Pharmacokinetics and Safety of Carfilzomib in Patients With Multiple Myeloma and Renal Disease

End-stage Renal Disease | Relapsed Multiple Myeloma

United States, Australia, Canada
Massachusetts General Hospital
Conquer Cancer Foundation

Active, not recruiting

Improving Patient and Caregiver Understanding of Risks and Benefits of Immunotherapy for Advanced Cancer (UPLIFT)

Stage IV Non-Small Cell Lung Cancer | Stage IV Bladder Cancer | Stage IV Breast Cancer | Stage IV Melanoma | Immunotherapy | Immune Checkpoint Inhibitors | Stage IV Gastric Cancer | Stage IV Merkel Cell Carcinoma | Stage IV Colorectal Cancer | Stage IV Esophageal Cancer | Advanced Lung Cancer | Stage IV Renal... and other conditions

United States
Stanford University

Terminated

Clinical and Pathologic Studies of Patients Undergoing Treatment With EGFR Inhibitors

Head and Neck Cancer | Colorectal Neoplasms | Lung Cancer | Colon Cancer | Colonic Neoplasms | Head and Neck Cancers | Anal, Colon, and Rectal Cancers | Colon/Rectal Cancer | Colon/Rectal Cancer Colon Cancer | Colon/Rectal Cancer Rectal Cancer | Colon/Rectal Cancer Anal Cancer | Head and Neck Cancers Lip | Head... and other conditions

United States
GeoVax, Inc.
National Cancer Institute (NCI)

Recruiting

SARS-CoV-2 Vaccine (GEO-CM04S1) Versus mRNA SARS-COV-2 Vaccine in Patients With Blood Cancer

Lymphoma | Leukemia | Plasma Cell Myeloma | Hematopoietic and Lymphoid System Neoplasm | COVID-19 Infection

United States
Duke University

Completed

Microvascular and Fibrosis Imaging Study

Autoimmune Diseases | Chronic Graft Versus Host Disease | Sickle Cell Disease

United States
Eastern Cooperative Oncology Group

Recruiting

Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials

Melanoma | Breast Cancer, NOS | CNS Primary Tumor, NOS | Cervical Cancer, NOS | Colorectal Cancer, NOS | Leukemia, NOS | Lymphoma, NOS | Miscellaneous Neoplasm, NOS | Non-Rhabdomyosarcoma Soft Tissue Sarcoma, NOS | Testicular Nonseminomatous Germ Cell Tumor, NOS | Thyroid Cancer, NOS | Bone Cancer, NOS

United States
Peking Union Medical College Hospital

Completed

Study on Microflora Characteristics of Pancreatic Solid Lesions Via Endoscopic Ultrasound-guided Fine Needle Aspiration/Biopsy

Pancreatic Carcinoma | Pancreatic Neuroendocrine Tumor | Autoimmune Pancreatitis | Microflora

China
Paul Szabolcs

Enrolling by invitation

Sequential Cadaveric Lung and Bone Marrow Transplant for Immune Deficiency Diseases (BOLT+BMT)

Chronic Granulomatous Disease (CGD) | Wiskott-Aldrich Syndrome | Severe Chronic Neutropenia | Severe Combined Immunodeficiency (SCID) | Immunodeficiency With Predominant T-cell Defect, Unspecified | Hyper IgE Syndromes | Hyper IgM Deficiencies | Mendelian Susceptibility to Mycobacterial Disease | Common...

United States

Clinical Trials on Leukemia, B-Cell, Chronic

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