Clinical Trials on Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor

Total 1173 results

Memorial Sloan Kettering Cancer Center

Recruiting

A Study of a Vaccine in Combination With Beta-glucan in People With Neuroblastoma

Neuroblastoma | High-risk Neuroblastoma | Metastatic Neuroblastoma

United States
Seattle Children's Hospital
The Evan Foundation; Ben Towne Center for Childhood Cancer Research

Active, not recruiting

Engineered Neuroblastoma Cellular Immunotherapy (ENCIT)-01

Neuroblastoma | Ganglioneuroblastoma

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Ethanol-Lock Treatment in Preventing Central Venous Catheter Infections in Patients With High-Risk Neuroblastoma

Neuroblastoma

United States
Giselle Sholler
Dell, Inc.

Completed

Molecular-Guided Therapy for Relapsed and Refractory Childhood Cancer

Medulloblastoma | Neuroblastoma | Brain Tumors | Rare Tumors

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Recruiting

Iodine I 131 Metaiodobenzylguanidine in Treating Patients With Recurrent, Progressive, or Refractory Neuroblastoma or Malignant Pheochromocytoma or Paraganglioma

Neuroblastoma | Pheochromocytoma

United States
University of Texas Southwestern Medical Center

No longer available

131I-Metaiodobenzylguanidine (131I-MIBG) Therapy for Relapsed/Refractory Neuroblastoma

Relapsed Neuroblastoma | Metastatic Pheochromocytoma

United States
Y-mAbs Therapeutics
Memorial Sloan Kettering Cancer Center

Terminated

Radiolabeled MAB Therapy in Patients With Refractory, Recurrent, or Advanced CNS or Leptomeningeal Cancer

Sarcoma | Brain and Central Nervous System Tumors | Neuroblastoma

United States
National Cancer Institute (NCI)

Completed

Docetaxel in Treating Children With Recurrent Solid Tumors

Sarcoma | Brain and Central Nervous System Tumors | Neuroblastoma

United States, Australia, Canada
Giselle Sholler
Beat NB Cancer Foundation; Because of Ezra; K C Pharmaceuticals Inc.

Completed

Study of Difluoromethylornithine (DFMO) in Combination With Bortezomib for Relapsed or Refractory Neuroblastoma

Neuroblastoma Recurrent

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Biological Therapy, Sargramostim, and Isotretinoin in Treating Patients With Relapsed or Refractory Neuroblastoma

Recurrent Neuroblastoma

United States, Canada
National University Hospital, Singapore

Unknown

Immunotherapy of Neuroblastoma Patients Using a Combination of Anti-GD2 and NK Cells (NKEXPGD2)

Neuroblastoma Recurrent

Singapore
Boehringer Ingelheim

Completed

Trial of Afatinib in Pediatric Tumours

Neuroectodermal Tumors | Rhabdomyosarcoma

United States, Spain, Canada, Germany, Italy, United Kingdom, Australia, Austria, Denmark, Faroe Islands, France, Netherlands
Samsung Medical Center

Recruiting

Response-based Treatment of High-risk Neuroblastoma

Newly Diagnosed High Risk Neuroblastoma

Korea, Republic of
Jakob Stenman
Novartis; Advanced Accelerator Applications

Recruiting

177Lutetium-DOTATATE in Children With Primary Refractory or Relapsed High-risk Neuroblastoma (LuDO-N)

Neuroblastoma | Neuroblastoma Recurrent

Sweden, Denmark, Lithuania, Norway, Netherlands
Giselle Sholler
Cortice Biosciences, Inc.

Terminated

Safety and Efficacy Study of TPI-287 in Neuroblastoma and Medulloblastoma

Medulloblastoma | Neuroblastoma

United States
Y-mAbs Therapeutics

Terminated

Naxitamab and GM-CSF in Combination With IT in Patients With High-Risk Neuroblastoma

Neuroblastoma Recurrent

Korea, Republic of, Hong Kong
Dana-Farber Cancer Institute
Patient-Centered Outcomes Research Institute

Active, not recruiting

Parental Decision-Making for Children With Relapsed Neuroblastoma

Relapsed Neuroblastoma

United States
South Plains Oncology Consortium

No longer available

Expanded Access Study of Fenretinide Lym-X-Sorb Plus Ketoconazole in Neuroblastoma

Neuroblastoma | Recurrent Neuroblastoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Studying Gene Expression in Samples From Younger Patients With Neuroblastoma

Neuroblastoma | Neoplastic Syndrome
National Cancer Institute (NCI)

Terminated

Interleukin-12 and Interleukin-2 in Treating Patients With Refractory or Recurrent Neuroblastoma

Recurrent Neuroblastoma

United States
Memorial Sloan Kettering Cancer Center

Completed

Local Injection of Pain Medication to Reduce Pain After Bone Marrow Procedures in Pediatric Neuroblastoma Patients

Neuroblastoma

United States
University of Virginia
National Cancer Institute (NCI)

Unknown

Activated T Cells Armed With GD2 Bispecific Antibody in Children and Young Adults With Neuroblastoma and Osteosarcoma

Recurrent Neuroblastoma | Disseminated Neuroblastoma

United States
Hong Kong Children's Hospital
The University of Hong Kong

Recruiting

Quadruple Immunotherapy for Neuroblastoma

Neuroblastoma Recurrent

Hong Kong
PersonGen BioTherapeutics (Suzhou) Co., Ltd.
Tianjin Medical University Cancer Institute and Hospital; Shandong Cancer Hospital...

Recruiting

TAA06 Injection in the Treatment of Patients With B7-H3-positive Relapsed/ Refractory Neuroblastoma

B7-H3-positive Relapsed/ Refractory Neuroblastoma

China
University Children's Hospital Tuebingen

Completed

CH14.18 1021 Antibody and IL2 After Haplo SCT in Children With Relapsed Neuroblastoma

Neuroblastoma Recurrent

Germany, Austria
University of Regensburg

Completed

Multimodal Molecular Targeted Therapy to Treat Relapsed or Refractory High-risk Neuroblastoma (RIST-rNB-2011)

Neuroblastoma Recurrent

Germany
Hospices Civils de Lyon

Unknown

MEK and Autophagy Inhibition in Metastatic/Locally Advanced, Unresectable Neuroblastoma RAS (NRAS) Melanoma (CHLOROTRAMMEL)

Metastatic NRAS Melanoma

France
Giselle Sholler
Cortice Biosciences, Inc.

Completed

TPI 287 in Patients With Refractory or Recurrent Neuroblastoma or Medulloblastoma

Medulloblastoma | Neuroblastoma | Relapse

United States
Giselle Sholler
Van Andel Research Institute

Completed

A Trial Using Molecular-Guided Therapy in Patients With Refractory or Recurrent Neuroblastoma

Refractory Neuroblastoma | Relapsed Neuroblastoma

United States
National Cancer Institute (NCI)
United Therapeutics

Completed

Irinotecan Hydrochloride and Temozolomide With Temsirolimus or Dinutuximab in Treating Younger Patients With Refractory or Relapsed Neuroblastoma

Recurrent Neuroblastoma | Ganglioneuroblastoma

United States, Canada, Australia, New Zealand, Puerto Rico
National Taiwan University Hospital

Unknown

A Pilot Study on ALK Gene Mutations in Neuroblastoma

Neuroblastoma

Taiwan
National Cancer Institute (NCI)

Terminated

Pyrazoloacridine and Stem Cell or Bone Marrow Transplantation in Treating Young Patients With High-Risk Neuroblastoma

Recurrent Neuroblastoma | Disseminated Neuroblastoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Lorvotuzumab Mertansine in Treating Younger Patients With Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial Sarcoma

Recurrent Neuroblastoma | Recurrent Rhabdomyosarcoma | Wilms Tumor | Recurrent Malignant Peripheral Nerve Sheath Tumor | Recurrent Synovial Sarcoma | Pleuropulmonary Blastoma

United States
Institute of Mother and Child, Warsaw, Poland
Maria Sklodowska-Curie National Research Institute of Oncology

Recruiting

Regorafenib in Patients With Refractory Primary Bone Tumors (Regbone)

Osteosarcoma | Ewing Sarcoma of Bone

Poland
Medical University of Vienna
Medical University of Graz; Charite University, Berlin, Germany; Hannover Medical... and other collaborators

Completed

Quality Improvement Project - "My Logbook! - I Know my Way Around!"; ("Mein Logbuch - Ich Kenne Mich Aus!")

Sarcoma | Hematologic Diseases | Leukemia | Brain Tumor | Neurofibromatoses | Neuroblastoma

Austria, Germany, Switzerland, Italy
Stephan Grupp MD PhD
Children's Hospital of Philadelphia; University of Pennsylvania; Tmunity Therapeutics

Recruiting

GPC2 CAR T Cells for Relapsed or Refractory Neuroblastoma (GPC2)

Refractory Neuroblastoma | High-risk Neuroblastoma | Relapsed Neuroblastoma

United States
Zhujiang Hospital

Completed

Anti-GD2 4th Generation CART Cells Targeting Refractory and/or Recurrent Neuroblastoma (4SCAR-GD2)

Effects of Immunotherapy | Neuroblastoma

China
Cancer Research UK

Completed

A Phase I Trial of Anti-GD2 T-cells (1RG-CART)

Relapsed or Refractory Neuroblastoma

United Kingdom
Children's Oncology Group
National Cancer Institute (NCI)

Completed

ABT-751 in Treating Children With Neuroblastoma That Has Relapsed or Not Responded to Previous Treatment

Recurrent Neuroblastoma | Disseminated Neuroblastoma

United States, Canada
PersonGen BioTherapeutics (Suzhou) Co., Ltd.
The First Affiliated Hospital of Zhengzhou University

Not yet recruiting

Clinical Study of CD276 Targeted Autologous Chimeric Antigen Receptor T Cell Infusion in Patients With CD276 Positive Advanced Solid Tumor

Gastric Cancer | Lung Cancer | Osteosarcoma | Neuroblastoma
National Cancer Institute (NCI)

Completed

Phase I Study of Ipilimumab (Anti-CTLA-4) in Children and Adolescents With Treatment-Resistant Cancer

Sarcoma | Lymphoma | Neuroblastoma | Wilm's Tumor

United States
John Maris

Available

131-I-MIBG Therapy for Refractory Neuroblastoma, Expanded Access Protocol

Neuroblastoma | Childhood Metastatic Pheochromocytoma

United States
St. Jude Children's Research Hospital

Completed

Recombinant Human Thrombopoietin in Children Receiving Ifosfamide, Carboplatin, and Etoposide Chemotherapy

Osteosarcoma | Neuroblastoma | Rhabdomyosarcoma | Hepatic Cancer | Germ Cell Tumors

United States
Matthew Ingham
Takeda; Karyopharm Therapeutics Inc

Withdrawn

Selinexor in Combination With Ixazomib for the Treatment of Advanced Sarcoma

Sarcoma | Ewing Sarcoma | Liposarcoma | Alveolar Soft Part Sarcoma | Malignant Peripheral Nerve Sheath Tumors

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
Baxter Healthcare Corporation; Amgen; Nexell Therapeutics Inc

Completed

Peripheral Stem Cell Transplantation Plus Chemotherapy in Treating Patients With Malignant Solid Tumors

Sarcoma | Testicular Germ Cell Tumor | Ovarian Cancer | Brain and Central Nervous System Tumors | Neuroblastoma | Liver Cancer | Extragonadal Germ Cell Tumor | Childhood Germ Cell Tumor

United States
Medical College of Wisconsin
National Cancer Institute (NCI)

Completed

Gallium Nitrate in Treating Children With Brain Tumor, Neuroblastoma, Rhabdomyosarcoma, Non-Hodgkin's Lymphoma, or Refractory Solid Tumors

Sarcoma | Lymphoma | Unspecified Childhood Solid Tumor, Protocol Specific | Brain and Central Nervous System Tumors | Neuroblastoma

United States
Seattle Children's Hospital

Active, not recruiting

HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors

Glioma | Ependymoma | Medulloblastoma | Pineoblastoma | Central Nervous System Tumor, Pediatric | Germ Cell Tumor | Atypical Teratoid/Rhabdoid Tumor | Primitive Neuroectodermal Tumor | Choroid Plexus Carcinoma

United States
Seattle Children's Hospital

Active, not recruiting

EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors

Glioma | Ependymoma | Medulloblastoma | Pineoblastoma | Central Nervous System Tumor, Pediatric | Germ Cell Tumor | Atypical Teratoid/Rhabdoid Tumor | Primitive Neuroectodermal Tumor | Choroid Plexus Carcinoma

United States
Merck Sharp & Dohme LLC

Terminated

A Study of Robatumumab (SCH 717454, MK-7454) in Combination With Different Treatment Regimens in Pediatric Participants With Advanced Solid Tumors (P05883, MK-7454-006)

Neoplasms | Bone Cancer | Neuroblastoma | Solid Tumors | Kidney Tumor
National Cancer Institute (NCI)

Completed

Monoclonal Antibody Therapy With Sargramostim and Interleukin-2 in Treating Children With Neuroblastoma

Recurrent Neuroblastoma | Disseminated Neuroblastoma | Regional Neuroblastoma

United States

Clinical Trials on Localized Ewing Sarcoma/Peripheral Primitive Neuroectodermal Tumor

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