Clinical Trials on Lymphatic Abnormalities

Total 36646 results

Palvella Therapeutics, Inc.

Recruiting

Study Evaluating the Safety and Efficacy of PTX-022 (QTORIN Sirolimus) in the Treatment of Microcystic Lymphatic Malformations

Microcystic Lymphatic Malformation

United States
Nanjing Children's Hospital

Recruiting

A Prospective Study on the Treatment of cLM Based on ICG Imaging

Lymphatic Malformation

China
Protara Therapeutics

Recruiting

Safety and Efficacy Study of Intracystic TARA-002 for the Treatment of Lymphatic Malformations in Participants 6 Months to Less Than 18 Years of Age (STARBORN-1)

Lymphatic Malformation

United States
Avalo Therapeutics, Inc.

Withdrawn

A Pharmacokinetic, Pharmacodynamic, Safety and Tolerability Study of CERC-006 in Adults With Complex Lymphatic Malformations

Lymphatic Malformation

United States
University Hospital, Tours

Recruiting

TOPical Sirolimus in linGUal Microcystic Lymphatic Malformation -TOPGUN (TOPGUN)

Lingual Microcystic Lymphatic Malformations

France
University Hospital, Tours
University Hospital, Angers

Recruiting

Topical Sirolimus in Cutaneous Lymphatic Malformations (TOPICAL)

Vascular Malformations | Lymphatic Malformation

France
Medical University of South Carolina

Recruiting

Weekly Sirolimus Therapy

Lymphatic Malformation | Venous Malformation

United States
Palvella Therapeutics, Inc.

Not yet recruiting

A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study Evaluating Safety and Efficacy of QTORIN 3.9% Rapamycin Anhydrous Gel in the Treatment of Microcystic Lymphatic Malformations (SELVA)

Microcystic Lymphatic Malformation

United States
Novartis Pharmaceuticals

Recruiting

Alpelisib in Pediatric and Adult Patients With Lymphatic Malformations Associated With a PIK3CA Mutation. (EPIK-L1)

Lymphatic Malformations

Spain, France, Germany, Australia, United States
Stanford University
Ann & Robert H Lurie Children's Hospital of Chicago

Completed

Sildenafil for the Treatment of Lymphatic Malformations

Lymphatic Diseases | Lymphatic Malformations

United States
Richard JH Smith

Completed

OK432 (Picibanil) in the Treatment of Lymphatic Malformations

Lymphatic Malformations

United States
Medical College of Wisconsin

Terminated

Selenium in the Treatment of Complicated Lymphatic Malformations

Lymphatic Malformations

United States
West China Hospital

Completed

Clinical Characteristics of Lymphatic Malformations

Lymphangioma | Lymphatic Malformation

China
Venthera, Inc., a BridgeBio company

Terminated

First in Human Trial of Topical VT30 in Pts With Venous/Lymphatic Malformations Assoc With PIK3CA or TEK Gene Mutations

Lymphatic Malformation | Venous Malformation | Venolymphatic Malformation

United States
University of Iowa

Completed

Study of Picibanil (OK432) Sclerotherapy in Children With Macrocystic Lymphatic Malformations

Lymphatic Malformations

United States
Sohag University

Recruiting

Role of Sirolimus in Treatment of Microcystic , Mixed Lymphatic and Vascular Malformations

Vascular Malformations | Microcystic Lymphatic Malformation | Combined Vascular Malformation

Egypt
University Hospital, Lille
Ministry of Health, France

Recruiting

Efficacy of Rapamycin in the Treatment of Cervico-facial Lymphatic Malformations (RAPAMALYMPH)

Pediatric | Lymphatic Malformation

France
Stanford University

Completed

A Study to Evaluate Sildenafil for the Treatment of Lymphatic Malformations

Lymphangioma

United States
University of Arkansas

Completed

Airway Vascular Lesions

Lymphatic Malformations | Hemangiomas | Venous Malformations
University of Aarhus
Rigshospitalet, Denmark; InCor Heart Institute; Hospital das Clínicas de Ribeirão...

Completed

Lymphatic Function in Patients With a Fontan Circulation From Brazil

Univentricular Heart | Lymphatic Abnormalities | Lymphatic Edema

Denmark
University of Aarhus

Unknown

Lymphatic Function in Patients With a Fontan-Kreutzer Circulation

Univentricular Heart | Lymphatic Abnormalities | Lymphatic Edema
Children's Hospital of Fudan University

Recruiting

Percutaneous Administration of Sirolimus in the Treatment of Superficial Complicated Vascular Anomalies

Kaposiform Hemangioendothelioma | Tufted Angioma | Superficial Vascular Anomalies | Superficial Lymphatic Malformations

China
Eunice Kennedy Shriver National Institute of Child...

Recruiting

A Prospective Natural History Study of Lymphatic Anomalies

Lymphatic Diseases | Lymphatic Abnormalities

United States
University of Arkansas

Completed

Diagnosis of Hemangiomas and Vascular Malformations

Arteriovenous Malformations | Vascular Malformations | Lymphatic Malformations | Hemangiomas | Venous Malformations | Venular Malformations
Children's Hospital Medical Center, Cincinnati

Unknown

Safety and Efficacy Study of Sirolimus in Complicated Vascular Anomalies

Tufted Angioma | Microcystic Lymphatic Malformation | Kaposiform Hemangioendotheliomas | Capillary Venous Lymphatic Malformation | Venous Lymphatic Malformation | Mucocutaneous Lymphangiomatosis and Thrombocytopenia | Capillary Lymphatic Arterial Venous Malformations | PTEN Overgrowth Syndrome With... and other conditions

United States
Mayo Clinic

Completed

Vascular Anomaly Pathology and Genomics Biopsy Study

Hemangioma | Arteriovenous Malformations | Vascular Malformations | Lymphatic Malformation | Venous Malformation | Vascular Anomaly | Klippel Trenaunay Syndrome

United States
Radboud University Medical Center

Recruiting

Lymphatic Phenotype in Noonan Syndrome Spectrum Disorders (LENS)

Lymphatic Diseases | Noonan Syndrome | Lymphatic Disease | Lymphatic System Disorders Congenital

Netherlands
Institut National de la Santé Et de la Recherche...

Recruiting

National Evaluation of Patients With PIK3CA-Related Overgrowth Spectrum (PROS) (COSY)

Vascular Malformations | PIK3CA-related Overgrowth Spectrum | Megalencephaly | Lymphatic Malformation | CLOVES Syndrome | Venous Malformation | Klippel Trenaunay Syndrome | MCAP | Macrodactyly

France
Laboratoires Vivacy

Recruiting

Study of a Novel Hyaluronic Acid Based Gel for Volume Deficiency in the Mid-face (FaceHyal) (FaceHyal)

Aging | Aesthetics | Volume Deficiency in the Mid-Face

France
Murdoch Childrens Research Institute
Royal Children's Hospital; Peter MacCallum Cancer Centre, Australia

Not yet recruiting

A Trial of Targeted Therapies for Patients With Slow-Flow or Fast-Flow Vascular Malformations (TARGET-VM)

Arteriovenous Malformations | Vascular Malformations | MAP2K1 Gene Mutation | PIK3CA-related Overgrowth Spectrum | Vascular Anomalies | Lymphangioma | Lymphatic Malformation | KRAS G12D | Venous Malformation | Vascular Anomaly | KRAS G12C | PI3K Gene Mutation | Slow-Flow Vascular Malformation | Fast-Flow Vascular... and other conditions

Australia
National Institute of Dental and Craniofacial Research...

Terminated

Effects of PTH Replacement on Bone in Hypoparathyroidism

DiGeorge Syndrome | Hypoparathyroidism

United States
Children's Healthcare of Atlanta

Terminated

Prevalence and Clinical Spectrum of the 22q11 Deletion

Congenital Disorders

United States
University of Sao Paulo
University of Aarhus; Fundação de Amparo à Pesquisa do Estado de São Paulo; Copenhagen...

Completed

Lymphatic Function in Patients With Fontan Circulation: Effect of Physical Training

Quality of Life | Exercise Training | Congenital Heart Disease | Univentricular Heart | Functional Capacity | Lymphatic Abnormalities

Brazil
Innovation Research & Training

Recruiting

Mindfulness Program for Adolescents With 22q11DS

22Q11 Deletion Syndrome

United States
Sumitomo Pharma Switzerland GmbH

Recruiting

Congenital Athymia Patient Registry

Complete DiGeorge Anomaly | Complete DiGeorge Syndrome | Congenital Athymia

United States
Enzyvant Therapeutics GmBH
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Parathyroid and Thymus Transplantation in DiGeorge #931

DiGeorge Syndrome | Hypoparathyroidism | Complete DiGeorge Syndrome

United States
Hôpital le Vinatier

Recruiting

Arithmetic Abilities in Children With 22q11.2DS (ARITH22)

22q11.2 Deletion Syndrome

France
Nobias Therapeutics, Inc.

Completed

NB-001 in Children and Adolescents With 22q11 Deletion Syndrome

22q11 Deletion Syndrome

United States, Canada
University of Geneva, Switzerland

Completed

Effects of Methylphenidate on Brain and Cognition in 22q11 Deletion Syndrome

22q11.2 Deletion Syndrome

Switzerland
Hôpital le Vinatier

Terminated

Social Cognition Training and Cognitive Remediation (RCKID)

22q11.2 Deletion Syndrome

France
Albert Einstein College of Medicine
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Examining Genetic Factors That Affect the Severity of 22q11.2 Deletion Syndrome

DiGeorge Syndrome | 22q11.2 Deletion Syndrome

United States
University of Geneva, Switzerland

Terminated

Neuroprotective Effects of Risperdal on Brain and Cognition in 22q11 Deletion Syndrome

22q11.2 Deletion Syndrome

Switzerland
Enzyvant Therapeutics GmBH
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Terminated

Serum-Free Thymus Transplantation in DiGeorge Anomaly (SerumFree)

DiGeorge Anomaly
Rigshospitalet, Denmark

Completed

Lymphatic Magnetic Resonance Imaging Abnormalities in Children With Tetralogy of Fallot: A Case-Control Study

Tetralogy of Fallot | Lymphatic

Denmark
National Center for Research Resources (NCRR)
Children's Hospital of Philadelphia

Unknown

Immunologic Evaluation in Patients With DiGeorge Syndrome or Velocardiofacial Syndrome

Abnormalities, Multiple | DiGeorge Syndrome | Chromosome Abnormalities | Conotruncal Cardiac Defects | Shprintzen Syndrome

United States
Stephan Eliez

Recruiting

Using Transcranial Alternating Current Stimulation to Improve Executive Function in 22q11.2 Deletion Syndrome

tACS | 22Q11 Deletion Syndrome

Switzerland
Zynerba Pharmaceuticals, Inc.

Completed

Open-Label Study of ZYN002 Administered as a Transdermal Gel to Children and Adolescents With 22q11.2 Deletion Syndrome (INSPIRE)

22Q Deletion Syndrome

United States, Australia
Aevi Genomic Medicine, LLC, a Cerecor company

Completed

Safety and Efficacy Study of NFC-1 in Subjects Aged 12-17 Years With 22q11.2DS & Associated Neuropsychiatric Conditions

22q11.2 Deletion Syndrome

United States
Enzyvant Therapeutics GmBH
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Thymus Transplantation in DiGeorge Syndrome #668

DiGeorge Syndrome | Complete Typical DiGeorge Anomaly

United States
National Institute of Mental Health (NIMH)

Completed

Velocardiofacial (VCFS; 22q11.2; DiGeorge) Syndrome Study

DiGeorge Syndrome | Velocardiofacial Syndrome | 22q11.2 Syndrome

United States

Clinical Trials on Lymphatic Abnormalities

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