Clinical Trials on M-protein Related Cardiac Disease in South Africa

Total 2819 results

University of Pretoria

Completed

Laparascopy Versus Laparatomy in the Management of Ruptured Ectopic Pregnancy

Ruptured Ectopic Pregnancy

South Africa
University of Pretoria

Completed

A Trial to Compare American Heart Association (AHA) and Simple (SIM)Method to Give Adenosine to Treat Supra-ventricular Tachycardia (SVT) (AHAvsSIM)

Supra-ventricular Tachycardia

South Africa
GLYCAR SA (Pty) Ltd

Completed

Post Market Observational Retrospective Study of Glycar Bovine Pericardial Patch (CIP-003)

Cardiac Anomaly | Cardiac Defect | Pericardial Defect

South Africa
Catalyst Biosciences

Completed

Study of Next-Generation Recombinant Factor IX Variant in Adult Subjects With Hemophilia B

Hemophilia B

South Africa
Medtronic BRC

Terminated

Model 20105 Lead Study

Sick Sinus Node Syndrome

South Africa, Netherlands, Canada, Singapore
University of California, San Francisco
National Institute on Alcohol Abuse and Alcoholism (NIAAA); Human Sciences... and other collaborators

Active, not recruiting

Couple-Based Motivational Interviewing With Mobile Breathalyzers to Reduce Alcohol Use in South Africa

HIV/AIDS | Alcohol Abuse

South Africa
University of Cape Town

Unknown

Sub-project: Use of Small Implantable ECG Recorder in Pregnant Women With Arrhythmia (REVEAL)

Arrhythmias in Pregnancy

South Africa
Penn State University
National Institute on Drug Abuse (NIDA)

Completed

Adolescent Drug and HIV Prevention in South Africa

Substance-Related Disorders | Sexually Transmitted Diseases

South Africa
Pace Clinic
University Hospital, Saarland

Completed

Renal Sympathetic Denervation Prevents Atrial Fibrillation in Patients With Hypertensive Heart Disease: a Pilot Study (RDPAF)

Hypertension | Atrial Fibrillation | Autonomic Imbalance | Hypertensive Heart Disease

South Africa
Aarhus University Hospital
University of Aarhus

Completed

Acute Kidney Injury After Cardiac Surgery: Novel Ultrasound Techniques for Prediction of Acute Kidney Injury

Acute Kidney Injury | Cardiac Surgery | Acute Renal Failure

Denmark, South Africa
Novo Nordisk A/S

Completed

Comparison of Two Insulin Aspart Formulations in Healthy Volunteers

Healthy | Diabetes

South Africa
Novo Nordisk A/S

Completed

Bioequivalence of Two Formulations of Biphasic Insulin Aspart 50 in Healthy Male Subjects

Healthy | Diabetes

South Africa
Eli Lilly and Company

Completed

A Study to Compare the Pharmacokinetics and Pharmacodynamics of LY2963016 to Lantus in Healthy Participants

Diabetes Mellitus

South Africa
RTI International
National Institute on Alcohol Abuse and Alcoholism (NIAAA); Medical Research...

Completed

Venue-Based Couples CoOp in South Africa (Couples CoOp)

HIV Infections | Alcoholism

South Africa
Novo Nordisk A/S

Completed

Bioequivalence of Two Formulations of Biphasic Insulin Aspart 70 in Healthy Male Subjects

Healthy | Diabetes

South Africa
University of California, Los Angeles
National Institute on Drug Abuse (NIDA)

Completed

HIV & Drug Abuse Prevention for South African Men

Substance-Related Disorders | Alcoholism | Human Immunodeficiency Virus

South Africa
University of North Carolina, Chapel Hill
National Institute on Alcohol Abuse and Alcoholism (NIAAA); University of Stellenbosch and other collaborators

Completed

The Trajectory of Fetal Alcohol Spectrum Disorders (FASD) Across the Life Span: Continuing Prevention and Longitudinal Epidemiology

Fetal Alcohol Spectrum Disorders

South Africa
University of California, Los Angeles

Active, not recruiting

Neighborhood Alcohol & HIV Prevention in South African Townships (Philani)

Nutrition Disorders | HIV | Fetal Alcohol Syndrome

South Africa
Brown University
National Institute of Mental Health (NIMH); University of Cape Town

Completed

Adherence to HIV Treatment Postpartum: The Implications of Transitions Among Women Living With HIV in South Africa

HIV | Pregnancy Related

South Africa
University of Johannesburg
Medical Research Council, South Africa

Enrolling by invitation

Evaluation of the Impact of a Personal and Domestic Hygiene Intervention on Lead Exposure in a Community Close to a Mine Dump

Lead Poisoning | Lead Poison Children

South Africa
Children's Mercy Hospital Kansas City
University of the Western Cape

Completed

Adapting the Diabetes Prevention Program for a Developing World Context

Weight Loss

South Africa
University of Pretoria

Unknown

The Efficacy of Specialist Collaboration and Mobile Screening for Improving the Management of Diabetes (CCMSD)

Diabetes

South Africa
Boston University
World Bank (Lead institution); Republic of South Africa National Department...

Completed

Evaluation of South Africa's National Adherence Strategy (ENHANCE)

Hypertension | Diabetes | HIV | Tuberculosis

South Africa
University of Athens

Recruiting

Arrhythmic Risk Stratification in Nonischemic Dilated Cardiomyopathy (ReCONSIDER)

Dilated Cardiomyopathy | Sudden Cardiac Death Due to Cardiac Arrhythmia

Greece
University of Cape Town
Stanford University

Recruiting

Point-of-care Ultrasound Abnormalities in Early Onset Preeclampsia

Preeclampsia | Pulmonary Edema | Cardiac Function

South Africa
Wits Health Consortium (Pty) Ltd
Discovery Vitality

Active, not recruiting

Testing the Effectiveness of Different Messaging Approaches to Increase Doctor Visits Amongst Individuals With Risk Factors for Diabetes

Type 2 Diabetes | Pre-diabetes

South Africa
University of North Carolina, Chapel Hill
University of Pretoria; SADC Research Centre

Completed

Impact Evaluation of a School-Based Sexuality and HIV Prevention Education Activity in South Africa

HIV Infections | Pregnancy Related | HSV-2 Infection

South Africa
RTI International
University of Cape Town

Completed

Treating South African Pregnant Women for Methamphetamine

HIV | Drug Addiction

South Africa
Eunice Kennedy Shriver National Institute of Child...
Medical Research Council, South Africa

Completed

Women-Focused HIV Prevention in the Western Cape (WC-WHC)

HIV | Substance Abuse | Violence

South Africa
University of Pretoria
South African Sugar Association

Completed

Nutrition Education Intervention for Adults With Type 2 Diabetes

Type 2 Diabetes Mellitus

South Africa
Wayne State University
Columbia University; University of Cape Town

Recruiting

RCT of Prenatal Choline Supplementation During Pregnancy to Mitigate Adverse Effects of Prenatal Alcohol Exposure

Fetal Alcohol Spectrum Disorders | Fetal Alcohol Syndrome

South Africa
Boston University
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Completed

Non-Communicable Diseases and Antiretroviral Therapy Outcomes in the RapIT Study Population (RapIT-NCD)

Cardiovascular Diseases | Diabetes Mellitus, Type 2 | Antiretroviral Therapy, Highly Active

South Africa
University of Cape Town
Medical Research Council, South Africa

Completed

A Trial Of Intravenous N-Acetylcysteine In The Management Of Antituberculous Drug-Induced Hepatitis (NAC in TB DIH)

Drug-Induced Liver Injury

South Africa
University of Witwatersrand, South Africa
GlaxoSmithKline; University of Oxford; Medical Research Council, South Africa; University...

Completed

Determinants of Type 2 Diabetes Risk in Middle-aged Black South African Men and Women

Diabetes Mellitus, Type 2 | Insulin Resistance | Menopause | Hiv

South Africa
RTI International
Medical Research Council, South Africa

Recruiting

Couples Health CoOp Plus (CHC+)

HIV | Substance Use | Stigma, Social

South Africa
Columbia University
National Institute of Mental Health (NIMH); University of Cape Town

Recruiting

A Randomized Trial of ImpACT+, a Coping Intervention for HIV Infected Women With Sexual Trauma in South Africa (ImpACT+)

HIV | Trauma Exposure

South Africa
University of Maryland, College Park
National Institute on Drug Abuse (NIDA); University of Miami; Weill Medical College... and other collaborators

Recruiting

Project Khanya: Peer-Delivered Intervention to Improve HIV Medication Adherence and Substance Use in South Africa

Alcohol-Related Disorders | Substance Use | Drug Use | Human Immunodeficiency Virus

South Africa
University of California, Los Angeles
University of Stellenbosch; The ELMA Foundation; Philani Maternal Child Health...

Completed

Evaluation of a Home-based Community Health Worker Program in Rural Eastern Cape, South Africa

Depression | HIV Infections | Alcohol Drinking | Alcohol; Harmful Use | HIV/AIDS | Depressive Symptoms | Child Development | Alcohol Use Disorder | Stunting | Child Nutrition Disorders | Child Malnutrition | Birth Weight Less Than 10Th Percentile

South Africa
Vanderbilt University
National Institute of Mental Health (NIMH); University of California, San Francisco and other collaborators

Completed

CareConekta: A Smartphone App to Improve Engagement in HIV Care

HIV/AIDS | Pregnancy Related

South Africa
University of KwaZulu
Cambridge University Hospitals NHS Foundation Trust; University of Oxford; University...

Completed

Durban Diabetes Study:A Study of the Epidemiology of Diabetes Mellitus in Urban South Africans of African Descent (DDS) (DDS)

Hyperglycemia | Diabetes Mellitus | Glucose Intolerance | Hereditary Diseases

South Africa
Lannett Company, Inc.
Parexel; FARMOVS (Pty) Ltd

Completed

A Study to Demonstrate Pharmacokinetic and Pharmacodynamic Biosimilarity Between HEC-Glargine and US-Lantus® in Healthy Male Volunteers

Type 2 Diabetes Mellitus | Type 1 Diabetes Mellitus

South Africa
University of Cape Town
Medtronic

Suspended

Left Cardiac Sympathetic Denervation for Cardiomyopathy Feasibility Pilot Study (LCSD)

Dilated Cardiomyopathy | Ischemic Cardiomyopathy | Non-ischemic Cardiomyopathy

South Africa
Bayer

Completed

Study of FVIIa Variant BAY86-6150 (B0189) in Subjects With Moderate or Severe Hemophilia Types A or B With or Without Inhibitors (MATCHBOX)

Hemophilia A | Hemophilia B

South Africa, Poland, United Kingdom
Baxalta now part of Shire

Terminated

Study of Modified Recombinant Factor VIII (OBI-1) in Subjects With Congenital Hemophilia A

Hemophilia A

United States, South Africa, United Kingdom
University of Maryland, College Park
National Institute on Drug Abuse (NIDA); Medical Research Council, South Africa

Active, not recruiting

Siyakhana Peer: Evaluating a Peer Recovery Coach Model to Reduce Substance Use Stigma in South African HIV Care

Substance-Related Disorders | HIV | Substance Use | Substance Use Disorders | Treatment Adherence | Treatment Adherence and Compliance | Stigmatization | Delivery of Health Care | Stigma, Social | Attitude of Health Personnel | Community Health Workers | Health Personnel | Health Personnel Attitude | Health Care Seeking... and other conditions

South Africa
University of Pretoria
Nestlè Nutrition Institute Africa; South African Sugar Association

Completed

Nutrition Education Intervention in Adults With Type 2 Diabetes Mellitus in a Resource Poor Setting

Diabetes Mellitus, Type II [Non-insulin Dependent Type] [NIDDM Type] Uncontrolled

South Africa
University of Stellenbosch
Stanley Medical Research Institute

Completed

Ethyl-Eicosapentaenoic Acid and Tardive Dyskinesia

Schizophrenia | Dyskinesia

South Africa
University of Maryland, College Park
National Institute of Mental Health (NIMH); Medical Research Council, South...

Completed

Community Health Worker Training to Reduce Depression and Substance Use Stigma in TB/HIV Care in South Africa (Siyakhana)

Substance-Related Disorders | Depression | Tuberculosis | Hiv | Mental Health Disorder | Mental Disorder | Health Care Utilization | Treatment Adherence and Compliance | Social Stigma | Attitude of Health Personnel | Community Health Workers | Health Care Delivery

South Africa
Sanofi

Completed

American-Australian-African Trial With Dronedarone in Patients With Atrial Fibrillation or Atrial Flutter for the Maintenance of Sinus Rhythm (ADONIS)

Atrial Fibrillation | Atrial Flutter

United States, Canada, Argentina, South Africa, Australia
Novartis Pharmaceuticals

Completed

Pharmacokinetics and Safety of Single Subcutaneous Pasireotide (SOM230) in Subjects With Varying Degrees of Hepatic Function

Alcoholism | Hepatic Cirrhosis

Germany, Belgium, United States, South Africa

Clinical Trials on M-protein Related Cardiac Disease in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Singapore

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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