Clinical Trials on MDR-TB

Total 600 results

Centre for the AIDS Programme of Research in South...
Amsterdam Institute for Global Health and Development; Global Alliance for... and other collaborators

Recruiting

Triage Test for All Oral DR-TB Regimen (TRiAD Study)

Tuberculosis | Drug Resistant Tuberculosis | MDR-TB | XDR-TB

Nigeria, South Africa, Ethiopia
The First Affiliated Hospital with Nanjing Medical...

Unknown

Study of Adjunctive Recombinant Human Interleukin-2 Therapy in Patients With MDR-TB (rhIL-2)

MDR TB

China
Global Alliance for TB Drug Development

Completed

Various Doses and Durations of Linezolid Plus Bedaquiline & Pretomanid in Participants With Drug Resistant Tuberculosis (ZeNix)

Tuberculosis | Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Extensively Drug-Resistant Tuberculosis | Tuberculosis, MDR | XDR-TB | Pre-XDR-TB

South Africa, Russian Federation, Georgia, Moldova, Republic of
Shanghai Pulmonary Hospital, Shanghai, China
Huashan Hospital; Shanghai Public Health Clinical Center; Anhui Chest Hospital; No.85 Hospital, Changning, Shanghai, China and other collaborators

Recruiting

A Study of Ultrashort PRS Regimen V in the Treatment of MDR-TB

MDR-TB

China
IUATLD, Inc
Medical Research Council; Institute of Tropical Medicine, Belgium; Liverpool... and other collaborators

Completed

The Evaluation of a Standard Treatment Regimen of Anti-tuberculosis Drugs for Patients With MDR-TB (STREAM)

MDR-TB

Ethiopia, Georgia, India, Moldova, Republic of, Mongolia, South Africa, Uganda
Shanghai Pulmonary Hospital, Shanghai, China
Huashan Hospital; Shanghai Public Health Clinical Center; No.85 Hospital, Changning...

Recruiting

A Exploratory Study of Vγ2Vδ2 T Lymphocyte-based Immunotherapy for MDR-TB

Immunotherapy | MDR-TB

China
Jan-Willem C Alffenaar
University of Virginia; Kibong'oto Infectious Diseases Hospital

Completed

Saliva and Dried Blood Spot Therapeutic Drug Monitoring for MDR-TB in Tanzania

MDR-TB

Tanzania
University of Oxford

Completed

A Study of the Immunogenicity of M. Bovis BCG, Delivered Intradermally in Healthy Volunteers

TB

United Kingdom
University of Oxford

Completed

A Study of the Immunogenicity of BCG, Delivered Intradermally in Healthy Volunteers

TB

United Kingdom
University of Oxford
Medical Research Council

Completed

Safety, Immunogenicity, and Impact of MVA85A, on the Immunogenicity of the EPI Vaccines

TB

Gambia
University of Oxford

Completed

Study of the Safety and Immunogenicity of Bacille Calmette Guerin (BCG) Vaccine

TB

United Kingdom
Ina-Respond
National Institute of Health Research and Development, Ministry of Health... and other collaborators

Completed

Tuberculosis Research of INA-RESPOND On Drug Resistance (TRIPOD)

Lung Tuberculosis | MDR TB

Indonesia
University of Bergen

Completed

Cost and Cost-effectiveness of PTB+ Treatment in Southern Ethiopia

Smear-positive TB Cases

Ethiopia
Nordic MDS Group

Unknown

Individual Molecular MRD Monitoring for MDS Patients After Allo-SCT

MDS | SCT | MRD

Denmark, Norway, Sweden
Tuberculosis Research Centre, India
International Union Against Tuberculosis and Lung Diseases; Sarvodaya Charitable... and other collaborators

Active, not recruiting

Modified BPaL Regimen for Managing Pre-XDR TB and MDR (TI/NR) TB in India (mBPaL)

Pre-Extensively Drug-Resistant Pulmonary TB | Treatment Intolerant Multidrug-Resistant Pulmonary TB | Non-responsive Multidrug-Resistant Pulmonary TB

India
Seoul National University Hospital

Terminated

Comparison of the Effect Between Levofloxacin and Moxifloxacin Among MDR-TB Patients

TB

Korea, Republic of
National Institute of Allergy and Infectious Diseases...

Completed

Dose Escalation Study of SQ109 in Healthy Adult Volunteers

TB Multi-drug Resistant

United States
Far Eastern Memorial Hospital

Unknown

The Protective Effect for Liver Organ in Patients With Anti-TB Drugs Using of Acetylcysteine (NAC)

Protective Effect in TB-DIH | TB-DIH Means: Drug Induced Liver Function Abnormalities

Taiwan
Wits Health Consortium (Pty) Ltd
University of Cape Town; Perinatal HIV Research Unit of the University of the... and other collaborators

Active, not recruiting

Building Evidence for Advancing New Treatment for Rifampicin Resistant Tuberculosis (RR-TB) Comparing a Short Course of Treatment (Containing Bedaquiline, Delamanid and Linezolid) With the Current South African Standard of Care

Tuberculosis | Multi Drug Resistant Tuberculosis | Rifampicin Resistant Tuberculosis | Extensively Drug-Resistant Tuberculosis | Pre-XDR-TB

South Africa
The HIV Netherlands Australia Thailand Research...
Radboud University Medical Center; Bhumibol Adulyadej Hospital; Klang Hospital; Bamrasnaradura Infectious Diseases Institute and other collaborators

Recruiting

Efficacy, Safety and Pharmacokinetics of DTG With RIF

HIV/TB Coinfection

Thailand
Health Science Center of Xi'an Jiaotong University
Pakistan Institute of Medical Sciences; Quaid i Azam University Islamabad Pakistan

Completed

Impact of a Pharmacist-led Patient-centred Care Intervention Along With Text-Message Reminders, on the Management of Newly Diagnosed Tubercular Patients: a Protocol for a Randomized Controlled Trial'.

TB | Pulmonary TB

Pakistan
All India Institute of Medical Sciences, New Delhi
National AIDS Control Organisation

Completed

Efficacy and Safety of Concomitant Use of Nevirapine and Rifampicin With HIV-TB ("NVP")

HIV/TB Co-infection

India
Johns Hopkins University
National Institute of Allergy and Infectious Diseases (NIAID); National Institutes... and other collaborators

Active, not recruiting

A Nurse Case Management Intervention to Improve MDR-TB/HIV Co-Infection Outcomes

HIV | MDR-TB

South Africa
Serum Institute of India Pvt. Ltd.

Active, not recruiting

Study to Check the Efficacy and Safety of Recombinant BCG Vaccine in Prevention of TB Recurrence

Prevention of TB Recurrence

Bangladesh, India
Riverside University Health System Medical Center

Unknown

The Prognostic Value of Limited Transthoracic Echocardiogram (LTTE) During Trauma Resuscitation

Patients Who Are in Shock and Intubated in the Trauma Bay (TB)

United States
The HIV Netherlands Australia Thailand Research...
King Chulalongkorn Memorial Hospital; Srinagarind Hospital, Khon Kaen University and other collaborators

Active, not recruiting

Tuberculosis Preventive Therapy Among Latent Tuberculosis Infection in HIV-infected Individuals

HIV-infected Participants With Latent TB Infection in High TB Burden Country

Thailand
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Household Transmission Dynamics of Multidrug Resistant Enterobacterales (HOME)

Adults Patients, With Fecal Carriage of Multi-Drug Resistant Enterobacterales (MDR-E)
International AIDS Vaccine Initiative
Universidad de Zaragoza; Biofabri, SLU

Not yet recruiting

A Study to Evaluate the Efficacy, Safety and Immunogenicity of MTBVAC in IGRA Positive Adolescents and Adults Living in a TB Endemic Region.

Tuberculosis (TB)
GlaxoSmithKline

Completed

Safety and Immunogenicity of GSK Biological's Candidate Tuberculosis Vaccine Mtb72F/AS02 in Healthy PPD-negative Adults.

Tuberculosis (TB)

Belgium
University of Oxford
Imaxio

Completed

Phase I Trial Evaluating Safety and Immunogenicity of MVA85A-IMX313 Compared to MVA85A in BCG Vaccinated Adults

Tuberculosis (TB)

United Kingdom
Johns Hopkins University
National Institute of Allergy and Infectious Diseases (NIAID); Dr. D.Y. Patil...

Recruiting

Tuberculosis (TB) Aftermath

Tuberculosis (TB)

India
QIAGEN Gaithersburg, Inc

Withdrawn

QuantiFERON Access Clinical Performance Study Protocol

Tuberculosis (TB)
GlaxoSmithKline

Completed

Safety and Immunogenicity of GSK Biological's Candidate Tuberculosis Vaccine Mtb72F/AS02A in Healthy PPD-positive Adults

Tuberculosis (TB)

Switzerland
GlaxoSmithKline
Corixa Corporation

Completed

Safety and Immunogenicity of a Candidate Tuberculosis (TB) Vaccine Given to PPD-Negative Adults

Tuberculosis (TB)

United States
Boston College
Boston University; National Institute of Nursing Research (NINR); National Institutes... and other collaborators

Not yet recruiting

Systems Analysis and Improvement Approach to Prevent TB (SAIA-TB)

Tuberculosis | TB - Tuberculosis | TPT

South Africa
Qurient Co., Ltd.

Completed

A Phase 2 Study to Evaluate Early Bactericidal Activity, Safety, Tolerability, and Pharmacokinetics of Multiple Oral Doses of Telacebec (Q203)

Treatment-naïve, Sputum Smear-positive Patients With Drug-sensitive Pulmonary TB

South Africa
GlaxoSmithKline

Completed

Immunogenicity and Safety of a Candidate Tuberculosis (TB) Vaccine Given to Healthy Adults in a TB-endemic Region

Tuberculosis (TB) | Tuberculosis Vaccines

South Africa
St George's, University of London

Unknown

Innovative Reagents for Improving Rapid Diagnosis of Mycobacterial Infections (TIKA_TB)

Tuberculosis (TB)

United Kingdom
Sun Yat-sen University

Recruiting

A Prospective Multicenters Clinical Cohort Study of Stratified Treatment of Chinese Children With Systemic ALK(+) ALCL

Pediatric Cancer | Anaplastic Lymphoma | MDD | MRD | Lymphoma, Nonhodgkin

China
University Medical Center Groningen

Completed

PK/PD of Ertapenem In Patients With TB

PK of Ertapenem in TB Patients

Netherlands
Oxford Immunotec

Completed

Assessing the Ability of the T-SPOT®.TB Test (IQ)

Tuberculosis (TB)

South Africa
Farman Ullah Khan
Pakistan Institute of Medical Sciences; Shaheed Zulfiqar Ali Bhutto Medical... and other collaborators

Unknown

Promoting Overall Care and Management Related to Tuberculosis Infection Through Pharmaceutical Care and Text Messaging

Pulmonary TB

Pakistan
Peking University Third Hospital
Beijing Geriatric Hospital

Recruiting

Risk Factors and Biomarkers for Post-tuberculosis Lung Damage

Pulmonary TB

China
National Taiwan University Hospital

Unknown

The Role of Apoptosis Associated Markers in Pathogenesis of Pulmonary Tuberculosis

To Compare the Serum Apoptosis-associated Markers Between Patients With Active TB and Patients With LTBI | To Evaluate the Efficiency of Apoptosis-associated Markers to Differentiate Potential of Active TB From LTBI

Taiwan
Thomayer University Hospital
Charles University, Czech Republic

Recruiting

Cytometric Immunodiagnostics of Latent Tuberculosis Infection (LTBI)

BCG Vaccination Reaction | LTBI | TB

Czechia
Harvard University Faculty of Medicine
National Institute of Allergy and Infectious Diseases (NIAID); Brigham and... and other collaborators

Unknown

Epidemiology of MDR-TB in Peru (Estudio Epi)

TB Multi-drug Resistant

Peru
University of Stellenbosch

Completed

Xpert Ultra and Xpert HIV-VL in People Living With HIV

HIV/AIDS | TB - Tuberculosis | Antiretroviral Therapy, Highly Active

South Africa
Kafrelsheikh University
Ministry of Health, Saudi Arabia

Not yet recruiting

Utilizing the Crosstalk Among Chicoric Acid, 13-Cis Retinoic Acid(Aerosolized), Minocycline and Vitamin D as a Potent Quadrate Therapy for Treating Patients With Multidrug-resistant TB and Patient With Both Multidrug-resistant TB and COVID-19

Tuberculosis

Egypt, Saudi Arabia
Freundeskreis Für Internationale Tuberkulosehilfe...

Not yet recruiting

Evaluating the Accuracy of New Tests for TB Infection Diagnosis (TB infection)

Latent Tuberculosis | Tuberculosis | TB Infection

Vietnam
University of Luebeck
University Hospital Tuebingen; University of Giessen; University Hospital Freiburg and other collaborators

Recruiting

Monitoring of MDRO Dynamics and Resistance Mechanisms in a University Hospital Network (R-Net)

MDRO

Germany

Clinical Trials on MDR-TB

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Netherlands

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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