Clinical Trials on MPS - Mucopolysaccharidosis

Total 806 results

Sidney Kimmel Comprehensive Cancer Center at Johns...
Bristol-Myers Squibb; Bayer

Active, not recruiting

Study of PI3Kinase Inhibition (Copanlisib) and Anti-PD-1 Antibody Nivolumab in Relapsed/Refractory Solid Tumors With Expansions in Mismatch-repair Proficient (MSS) Colorectal Cancer

Colon Cancer | Unresectable or Metastatic Microsatellite Stable (MSS) Solid Tumor Along With Microsatellite Stable (MSS) Colon Cancer

United States
Cyclacel Pharmaceuticals, Inc.

Suspended

A Study to Investigate Fadraciclib (CYC065), in Subjects With Leukemia or Myelodysplastic Syndrome (MDS)

Leukemia | Myelodysplastic Syndrome(MDS)

United States
Fujifilm Pharmaceuticals U.S.A., Inc.

Completed

Study of FF-10501-01 in Patients With Relapsed or Refractory Hematological Malignancies

AML | MDS | CMML

United States
Esra ÖZER
KTO Karatay University

Recruiting

The Effect of Aromatherapy Application With Bergamot and Grapefruit Essential Oils on PMS (Aromatherapy)

Premenstrual Syndrome-PMS

Turkey
University of Dundee

Completed

Investigating Hereditary Cardiac Disease by Reprogramming Skin Cells to Heart Muscle (CLUE)

Eletrophysiology of iPS-derived Cardiomyocytes

United Kingdom
AstraZeneca

Completed

Study to Investigate the Effect of a Single Dose of AZD7624 on Inflammation Caused by an Endotoxin Challenge

LPS Challenge, Neutrophils

United Kingdom
University Hospital, Akershus

Recruiting

Precision Therapy Versus Standard Therapy in AML and MDS in Elderly (PALM)

MDS | AML, Adult

Norway
Coeptis Therapeutics
Duke University

Recruiting

Safety and Efficacy of Allogeneic NK Cell Infusions in Patients With Relapsed/Refractory AML and High Risk MDS

MDS | AML, Adult Recurrent

United States
Immune System Key Ltd
University of Miami Sylvester Comprehensive Cancer Center

Recruiting

Study of NEROFE, a Novel Hormone-Peptide in Adult Patients With Advanced MDS and AML

AML | Advanced MDS

United States
University Clinic Frankfurt

Active, not recruiting

Inter-rater Reliability of the ASA Classification (In-ASK)

ASA PS Klassifikation

Germany
University of Cologne

Not yet recruiting

Immun Response in Children With MIS-C

MIS-C Multisystem Inflammatory Syndrome in Children

Germany
Sidney Kimmel Comprehensive Cancer Center at Johns...
Merck Sharp & Dohme LLC

Active, not recruiting

Study of MK-3475 (Pembrolizumab) in Patients With Microsatellite Unstable (MSI) Tumors (Cohort D)

High Tumor Mutation Burden | High TMB (Tumor Mutation Burden) | MSS (Microsatellite Stable)

United States
Shaare Zedek Medical Center

Unknown

Homeopathic Treatment of Premenstrual Syndrome

Premenstrual Syndrome-PMS
Assiut University

Unknown

Platelet Indices in Decompensated Post Hepatitic Liver Cirrhosis

MPV | PDW
Kiadis Pharma
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute... and other collaborators

Withdrawn

Haplo-identical Natural Killer (NK) Cells to Prevent Post-Transplant Relapse in AML and MDS (NK-REALM)

Myelodysplastic Syndromes (MDS) | Acute Myeloid Leukemia (AML)

United States
New York Medical College

Completed

Human Placental-Derived Stem Cell Transplantation (HPDSC)

Mucopolysaccharidosis I | Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Niemann-Pick Disease | Mucopolysaccharidosis VI | Wolman Disease | Adrenoleukodystrophy | Batten Disease | Metachromatic Leukodystrophy | Diamond-Blackfan Anemia | Severe Aplastic Anemia | Fucosidosis | Gaucher... and other conditions

United States
Carelon Research

Active, not recruiting

Long-Term Outcomes After the Multisystem Inflammatory Syndrome in Children (MUSIC)

Multisystem Inflammatory Syndrome in Children (MIS-C)

United States, Canada
Samsung Medical Center

Unknown

Feasibility and Efficacy Study of Conditioning Regimen for Allogeneic Hematopoietic Cell Transplantation (HCT) With Fludarabine, Busulfan, and Total Body Irradiation (TBI)

Lymphoma | AML | MDS | CML | ALL

Korea, Republic of
Ascentage Pharma Group Inc.
Suzhou Yasheng Pharmaceutical Co., Ltd.

Recruiting

A Phase Ib Study of APG-115 Single Agent or in Combination With Azacitidine or Cytarabine in Patients With AML and MDS.

Myelodysplastic Syndromes (MDS) | Acute Myeloid Leukemia (AML)

China
Singapore Eye Research Institute

Unknown

Ikervis for DED Due to GVHD Post Allo-HSCT (Ikervis)

Leukemia (Both ALL and AML) | MDS-EB-1

Singapore
Dilşad Sindel

Completed

Investigation of the Effectiveness of Muscle Inhibition and Space Correction Techniques of Kinesiotaping Method in Female Patients With Myofascial Pain Syndrome Related to Upper Trapezius Active Trigger Points

Female Patients With Myofascial Pain Syndrome (MPS) Related to Upper Trapezius Active Trigger Points (TP)
University Of Perugia

Recruiting

Allogeneic HSCT in MDS Patients Based on Risk According to R-IPSS

MDS and Allogeneic Stem Cell Transplantation

Italy
Astex Pharmaceuticals, Inc.

Completed

SGI-110 in Patients With Myelodysplastic Syndromes (MDS) or Acute Myelogenous Leukemia (AML)

AML | MDS | CMML

United States, Canada
Eli Lilly and Company
Loxo Oncology, Inc.

Active, not recruiting

Study of Oral LY3410738 in Patients With Advanced Hematologic Malignancies With IDH1 or IDH2 Mutations

Acute Myeloid Leukemia (AML) | Chronic Myelomonocytic Leukemia (CMML) | Myelodysplastic Syndrome (MDS) | Myeloproliferative Neoplasms (MPNs)

United States, Spain, Korea, Republic of, France, Taiwan, Australia, Belgium, Singapore, Israel, Canada, Germany, Finland
Spectrum Health Hospitals
Van Andel Research Institute; Community Foundation for Southeast Michigan (JP...

Completed

Evaluation of Formin Gene Status and Expression in Myeloproliferative and Myelodysplastic Disorders

AML | MDS | Myeloproliferative Disorder

United States
Terra Biological LLC

Completed

Oxaloacetate Supplementation for Emotional PMS (OAA4PMS)

Premenstrual Syndrome (PMS)
University of Dundee
University of Southampton; Newcastle University; University of Aberdeen; Chief... and other collaborators

Completed

Developing and Evaluating Interventions to Reduce Inappropriate Prescribing of Antibiotics in Primary Care (WIME)

Antibiotic Prescribing by GPs for URTI

United Kingdom
Cytheris, Inc.

Completed

Safety Study of IL-7 in Recipients of a Hemopoietic Stem Cell Transplant Peripheral Blood Stem Cell Transplant

AML | MDS | CML

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Center for Research Resources (NCRR); Otsuka Pharmaceutical Co., Ltd.

Completed

Safety Study of Bone Marrow Transplant Using Mismatched Tissue Followed by Chemotherapy

MDS | Lymphomas | Leukemias

United States
GWT-TUD GmbH

Completed

Assessment of Body, Liver and Labile Plasma Iron and Their Association With Outcome and Immunological Recovery in Myelodysplastic Syndrome (MDS) or Acute Myeloid Leukemia (AML) Patients Undergoing Allogeneic Stem Cell Transplantation - ALLIVE (ALLogeneic Iron inVEstigators) Observational Trial (ALLIVE)

MDS and AML Prior to Allogeneic SCT

Germany
University of Catanzaro

Completed

Matrix Metalloproteinases (MMPs),Neutrophil Gelatinase-associated Lipocalin (NGAL) Tissue and Plasma Levels and Aneurysms

MMPs and NGAL in Ruptured and Non-ruptured Aneurysms

Italy
Goethe University
Stichting Hemato-Oncologie voor Volwassenen Nederland; Polish Adult Leukemia... and other collaborators

Terminated

Panobinostat Maintenance After HSCT fo High-risk AML and MDS

Myelodysplastic Syndromes (MDS) | Acute Myeloid Leukaemia (AML)

Germany, Netherlands
Synta Pharmaceuticals Corp.

Completed

STA-9090 for Treatment of AML, CML, MDS and Myeloproliferative Disorders

Myeloproliferative Disorders | AML | MDS | CML

United States
GeNeuro Innovation SAS

Completed

Longitudinal Therapeutically Non-interventional Study of MSRV-Env Burden in Patients With Multiple Sclerosis Disease (LOMBARD)

Multiple Sclerosis (MS) | Clinically Isolated Syndrome (CIS) | Secondary Progressive MS | Primary Progressive MS | Relapsing-Remitting MS

France, Spain, Switzerland
PureTech

Recruiting

A Phase 1 Study With LYT-200 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML), or With Relapsed/Refractory, High-risk Myelodysplastic Syndrome (MDS)

MDS | AML, Adult Recurrent

United States
Anjali Sharathkumar
Amgen

Active, not recruiting

TPO-Mimetic Use in Children for Hematopoietic Failure

Thrombocytopenia | Bone Marrow Failure Disorders | Aplastic Anemia | Refractory Cytopenia of Childhood | Myelodysplastic Syndrome(MDS)

United States
OncoTherapy Science, Inc.

Terminated

Pharmacological Study of Intravenous OTS167 in Patients With Refractory or Relapsed Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, Advanced Myelodysplastic Syndromes, Advanced Myeloproliferative Neoplastic Disorders, or Advanced Chronic Myelogenous Leukemia

AML | Advanced MDS | ALL | Advanced CML | Advanced MPNs

United States
Institut fuer anwendungsorientierte Forschung und...
University Medical Center Goettingen

Completed

Screening and Genetic Monitoring of Patients With Myelodysplastic Syndromes (MDS) Under Different Treatment Modalities by Cytogenetic Analyses of Circulating CD34+Cells

Myelodysplastic Syndromes (MDS) | Chromosmal Aberrations | Karyotype Evolution | Rare Abnormalities | Cytogenetic Monitoring

Germany
Stanford University
Celgene Corporation

Terminated

Azacitidine + Lenalidomide Combo in the Elderly With Previously Treated AML & High-Risk MDS

Leukemia | Myelodysplastic Syndromes (MDS) | Acute Myeloid Leukemia (AML)

United States
Nantes University Hospital

Completed

Allogeneic Stem Cell Transplant With Clofarabine, Busulfan and Antithymocyte Globulin (ATG) for Adult Patients With High-risk Acute Myeloid Leukemia/Myelodysplastic Syndromes (AML/MDS) or Acute Lymphoblastic Leukemia (ALL) (Cloric)

AML | MDS | ALL | BAL

France
Assiut University

Recruiting

Expression Pattern of HNRNPH1 and HNRNPK Genes in MPNs

Myeloproliferative Neoplasms (MPNs)

Egypt
University of Illinois at Chicago

Recruiting

BMT-06: Study of Intensity Modulated Total Marrow Irradiation (IM-TMI)

Acute Leukemia | MDS

United States
Stanford University

Terminated

Investigation of Dysregulated Signaling in MPD Via Multiparameter Phospho-specific Flow Cytometry

Myeloproliferative Disorders | Myeloproliferative Disorders (MPD)

United States
Yale University
National Institute of Allergy and Infectious Diseases (NIAID); Hospital for...

Active, not recruiting

Pilot Study of Gut Commensals in Antiphospholipid Syndrome

Antiphospholipid Syndrome (APS)

United States
Samus Therapeutics, Inc.

Withdrawn

A Study of Zelavespib (PU-H71) in Subjects With AP-MPN or BP-MPN (AP-MPN)

Accelerated Phase MPN | Blast Phase MPN
Philipps University Marburg Medical Center
Linkoeping University

Completed

Treatment of Premenstrual Syndrome - Internet-based Self-help (praemensis)

Premenstrual Syndrome (PMS)

Germany
TJ Biopharma Co., Ltd.

Completed

A Study to Evaluate the Safety and Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of TJ011133 as Monotherapy and in Combination With Azacitidine (AZA) in Patients With Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

Acute Myeloid Leukemia (AML) | Myelodysplastic Syndromes(MDS)

China
Ruijin Hospital

Recruiting

Effect of Telitacicept on Antibody Titers in Primary APS Patients

Antiphospholipid Syndrome (APS)

China
Hospital for Special Surgery, New York

Recruiting

ESP Block in MIS Lumbar Spine Surgery

Patients With Spinal Stenosis Indicated for MIS TLIF

United States
University Hospital, Brest

Recruiting

Optical Genome Mapping in Hematological Malignancies (CARTOGEN)

MDS | ALL | Other Hematologic Malignant Neoplasms

France

Clinical Trials on MPS - Mucopolysaccharidosis

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