Clinical Trials on Macular Degeneration Advanced in Portugal

Total 556 results

Hoffmann-La Roche

Terminated

A Study Investigating the Safety and Efficacy of Lampalizumab Intravitreal Injections in Participants With Geographic Atrophy Secondary to Age-Related Macular Degeneration (SPECTRI)

Geographic Atrophy

United States, United Kingdom, Netherlands, Germany, Belgium, Poland, Spain, Argentina, Australia, Hungary, Italy, Portugal, France, Turkey, Austria, Russian Federation, Mexico, Peru, Denmark, Slovakia, Sweden, Switzerland
Chromaderm, Inc.

Completed

Effect of Ruboxistaurin on Clinically Significant Macular Edema

Diabetic Macular Edema

United States, Denmark, Mexico, Germany, Spain, Canada, Lithuania, Portugal, Romania, United Kingdom
Allergan

Completed

Safety and Efficacy of a New Treatment as Adjunctive Therapy to Anti-vascular Endothelial Growth Factor (Anti-VEGF) Treatment in Patients With Age-Related Macular Degeneration (AMD)

Choroidal Neovascularization | Age-Related Maculopathy

France, Korea, Republic of, New Zealand, Italy, Israel, United States, Portugal, Australia, United Kingdom
Clearside Biomedical, Inc.

Terminated

Suprachoroidal Injection of Triamcinolone Acetonide With IVT Aflibercept in Subjects With Macular Edema Following RVO (SAPPHIRE)

Macular Edema | Retinal Vein Occlusion

Spain, United States, Taiwan, Canada, Hungary, Israel, Portugal, Australia, Poland, United Kingdom, Austria, Denmark, India, Italy, Philippines, Slovakia
Hoffmann-La Roche

Completed

A Study to Evaluate the Long-Term Safety and Tolerability of Faricimab in Participants With Diabetic Macular Edema (Rhone-X)

Diabetic Macular Edema

United States, Korea, Republic of, United Kingdom, Brazil, Japan, Canada, Argentina, Australia, Austria, Denmark, France, Germany, Hungary, Italy, Poland, Slovakia, Spain, Singapore, Czechia, Hong Kong, Israel, Portugal, Russian Federation and more
Hoffmann-La Roche

Terminated

Long-Term Safety of Lampalizumab Intravitreal (ITV) Injections in Participants With Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (OMASPECT)

Geographic Atrophy

United States, United Kingdom, Germany, France, Turkey, Australia, Austria, Belgium, Canada, Denmark, Hungary, Italy, Poland, Slovakia, Spain, Switzerland, Portugal, Netherlands, Peru
Hoffmann-La Roche

Completed

A Study to Evaluate the Efficacy and Safety of Faricimab (RO6867461) in Participants With Diabetic Macular Edema (RHINE)

Diabetic Macular Edema

United States, Korea, Republic of, United Kingdom, Brazil, China, Canada, Argentina, Australia, Denmark, France, Italy, Poland, Spain, Germany, Singapore, Czechia, Hong Kong, Portugal, Russian Federation, Taiwan, Hungary, Switzerland and more
Centro Hospitalar De São João, E.P.E.

Completed

Are Postoperative Patient PROMS Influenced by Recall of Preoperative Scores?

Degenerative Diseases, Spinal Cord

Portugal
Bayer

Completed

Investigation of the Change of Vision-related Quality of Life in Subjects Treated With Aflibercept According to EU Label for DME. (AQUA)

Macular Edema

Spain, Canada, Switzerland, Portugal, Austria, Poland, Slovakia, United Kingdom, France, Czechia, Germany, Hungary, Italy, Lithuania
Pfizer

Terminated

An Open Label Trial to Investigate Macugen for the Preservation of Visual Function in Subjects With Neovascular AMD (PERSPECTIVES)

Macular Degeneration | Age Related Macular Degeneration (AMD) | Choroidal Neovascularization (CNV)

Canada, Belgium, United Kingdom, France, Poland, Spain, Turkey, Czech Republic, Italy, Greece, Germany, Austria, Portugal, Denmark, Finland
Novartis Pharmaceuticals

Completed

Randomized Study for Efficacy and Safety of Ranibizumab 0.5mg in Treat-extend and Monthly Regimens in Patients With nAMD (TREND)

Age-related Macular Degeneration | Choroidal Neovascularization

Korea, Republic of, Croatia, Germany, India, Russian Federation, Turkey, United Kingdom, Egypt, Israel, Belgium, Denmark, Hungary, Slovenia, Spain, Switzerland, Italy, Portugal, Slovakia, Chile
Pfizer

Completed

A Multi-Center Trial To Evaluate The Safety And Efficacy Of Pegaptanib Sodium(Macugen) Injected Into The Eye Every 6 Weeks For Up To 2 Years For Macular Swelling Associated With Diabetes, With An Open-Label Macugen Year Extension.

Macular Edema Associated With Diabetes Mellitus

United States, Colombia, Australia, Germany, Italy, South Africa, Greece, France, Austria, United Kingdom, Denmark, India, Portugal, Brazil, Canada, Czechia, Netherlands, Switzerland
Hoffmann-La Roche
Chugai Pharmaceutical

Completed

A Study to Evaluate the Efficacy and Safety of Faricimab in Participants With Macular Edema Secondary to Branch Retinal Vein Occlusion (BALATON)

Macular Edema | Branch Retinal Vein Occlusion

United States, Korea, Republic of, Brazil, Japan, United Kingdom, China, Argentina, Australia, France, Germany, Hungary, Italy, Poland, Spain, Singapore, Austria, Czechia, Hong Kong, Israel, Portugal, Russian Federation, Taiwan
Chromaderm, Inc.

Completed

Reduction in the Occurrence of Center-Involved Diabetic Macular Edema

Diabetic Retinopathy

United States, Canada, France, Denmark, Australia, Netherlands, Taiwan, Spain, Italy, Germany, Portugal, United Kingdom, Russian Federation, Poland, India, Brazil, Mexico
Bayer
Regeneron Pharmaceuticals

Completed

Vascular Endothelial Growth Factor (VEGF) Trap-Eye: Investigation of Efficacy and Safety in Wet Age-Related Macular Degeneration (AMD) (VIEW 2)

Macular Degeneration

Belgium, Israel, Italy, Spain, Korea, Republic of, Switzerland, Germany, Portugal, Japan, France, Australia, Netherlands, India, Austria, Brazil, Poland, United Kingdom, Singapore, Hungary, Latvia, Mexico, Czech Republic, Colombia, Ar... and more
Alcon Research

Terminated

Study of Travatan and Cosopt in Primary Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-angle Glaucoma

Portugal
Hoffmann-La Roche
Chugai Pharmaceutical

Completed

A Study to Evaluate the Efficacy and Safety of Faricimab in Participants With Macular Edema Secondary to Central Retinal or Hemiretinal Vein Occlusion (COMINO)

Central Retinal Vein Occlusion | Macular Edema | Hemiretinal Vein Occlusion

United States, Korea, Republic of, Brazil, Japan, United Kingdom, China, Argentina, Australia, France, Hungary, Italy, Poland, Spain, Singapore, Austria, Czechia, Germany, Hong Kong, Israel, Portugal, Russian Federation, Taiwan
Janssen Research & Development, LLC

Recruiting

A Study to Evaluate Intravitreal JNJ-81201887 (AAVCAGsCD59) Compared to Sham Procedure for the Treatment of Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD)

Geographic Atrophy

Netherlands, United States, Belgium, Italy, Germany, United Kingdom, Denmark, Spain, Czechia, Switzerland, Turkey, Canada, Hungary, Portugal, Poland, Australia, Sweden
Amunix, a Sanofi Company
Merck Sharp & Dohme LLC

Recruiting

To Access the Safety and Effects of Intravenous Administration of AMX-818 Alone and in Combination With Pembrolizumab in Adult Participants With Locally Advanced or Metastatic HER2-Expressing Cancers

Locally Advanced or Metastatic HER2-Expressing Cancers

Australia, Spain, France, Portugal
Bayer
Regeneron Pharmaceuticals

Recruiting

A Study to Learn How Well a Higher Amount of Aflibercept Given as an Injection Into the Eye Works and How Safe it is in People With Reduced Vision Due to Swelling in the Macula, Central Part of the Retina Caused by a Blocked Vein in the Retina (Macula Edema Secondary to Retinal Vein Occlusion) (QUASAR)

Macular Edema Secondary to Retinal Vein Occlusion

Japan, Korea, Republic of, China, Israel, Lithuania, United States, Italy, Spain, Hungary, Portugal, Serbia, Poland, United Kingdom, Thailand, Czechia, Austria, Germany, Turkey, Australia, Bulgaria, Estonia, France, Georgia, Latvia, Mal... and more
Novartis Pharmaceuticals

Completed

Ranibizumab Intravitreal Injections in Patients With Visual Impairment Due to Macular Edema Secondary to Central Retinal Vein Occlusion (CRYSTAL)

Central Retinal Vein Occlusion | Macular Edema

Greece, Hungary, Turkey, Australia, Austria, Netherlands, United Kingdom, Italy, Spain, Ireland, Portugal, Slovakia, Canada, Switzerland, Czech Republic, Poland, Denmark, Sweden
University of Coimbra

Completed

Unveiling Preclinical Idiopathic Macular Hole Formation (IMH_2012)

Idiopathic Macular Hole

Portugal
Allergan

Completed

An Exploratory Study to Evaluate the Safety of Brimonidine Intravitreal Implant in Patients With Retinitis Pigmentosa

Retinitis Pigmentosa

France, United States, Germany, Portugal
Hospital de Santa Maria, Portugal

Unknown

Internal Limiting Membrane and Macular Hole

C11.768.740

Portugal
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of Brolucizumab vs. Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema (KESTREL)

Diabetic Macular Edema

United States, Austria, Japan, Australia, Spain, Canada, Israel, Netherlands, Italy, United Kingdom, Portugal, Colombia, Puerto Rico, Argentina
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Ranibizumab in Two "Treat and Extend" Treatment Algorithms Versus Ranibizumab As Needed in Patients With Macular Edema and Visual Impairment Secondary to Diabetes Mellitus (RETAIN)

Diabetic Macular Edema

Belgium, United Kingdom, Netherlands, Ireland, Switzerland, Italy, Hungary, France, Spain, Portugal, Poland, Czech Republic, Greece
Centro Hospitalar de Lisboa Central
NOVA Medical School

Unknown

Continuous Passive Paracentesis for Intra-abdominal Hypertension (COPPTRIAHL)

Critical Illness | Cirrhosis, Liver | Ascites Hepatic | Paracentesis | Hypertension, Intraabdominal

Portugal
Instituto Portugues de Oncologia, Francisco Gentil...

Completed

Effectiveness of a Structured Intervention on the Development of Self-Care Behaviors With AVF in HD Patients (SISC-AVF)

Hemodialysis | Arteriovenous Fistula

Portugal
Universidade do Porto
University of Trieste; University of Padova; Hospital Centre Hospitalar de Trás-os-Montes... and other collaborators

Not yet recruiting

IUA Committee Research Project on the Management of TASC C and D Aortoiliac Lesions

Peripheral Arterial Disease | Peripheral Vascular Diseases | Aortoiliac Occlusive Disease | Aortoiliac Obstruction | Aortoiliac Atherosclerosis | Aortoiliac Atherosclerosis With Gangrene | Aortoiliac Atherosclerosis Without Gangrene

Portugal
Centro Hospitalar do Porto
University of Trás-os-Montes and Alto Douro; Foundation for Science and Technology... and other collaborators

Recruiting

Home-based Exercise Therapy for Patients With PAD (WalkingPAD)

Intermittent Claudication | Peripheral Arterial Disease (PAD)

Portugal
Centro Hospitalar de Lisboa Central

Completed

Screening of Diastolic Dysfunction With Impedance Cardiography in Hypertensive Patients (IMPEDDANS)

Hypertension | Diastolic Dysfunction

Portugal
Universidade do Porto
Fundação para a Ciência e a Tecnologia

Unknown

Effects of a Multicomponent Exercise Intervention on Physical and Cognitive Function of Older Adults With Dementia (Body&Brain)

Neurocognitive Disorders | Dementia | Alzheimer Disease | Vascular Dementia

Portugal
University of Trás-os-Montes and Alto Douro

Completed

Study of the Long-term Effects of Exercise on Heath Indicators in Older People

Lipid Metabolism Disorders | Sarcopenia | Osteoporosis | Overweight and Obesity | Personal Satisfaction | Hypertension With Complications and Secondary Hypertension

Portugal
Abbott Medical Devices

Terminated

AGIR Study: Angio-Seal in Interventional Radiology (AGIR)

Vascular Access Complication

Spain, Portugal
University of Trás-os-Montes and Alto Douro
Hospital Centre Hospitalar de Trás-os-Montes e Alto Douro; Research Center...

Not yet recruiting

Personalised Multicomponent Exercise Programme in Peripheral Arterial Disease

Peripheral Arterial Disease | Intermittent Claudication

Portugal
Universidade do Porto
Fundação para a Ciência e a Tecnologia; Centro Hospitalar De São João, E.P.E.; Instituto Nacional de Saúde Doutor Ricardo Jorge

Unknown

Study With an Innovative Equipment to Monitor and Control SALT During Cooking (iMC_SALT)

Hypertension | Salt; Excess

Portugal
Academia Cuf Descobertas
NOVA Medical School; CUF Academic and Research Medical Center; José de Mello... and other collaborators

Completed

Effect of a Multi-component Education Program on Salt Reduction in Adults

Hypertension | Blood Pressure

Portugal
Egas Moniz - Cooperativa de Ensino Superior, CRL
Ginásio Clube Português; Faculdade de Motricidade Humana - Universidade de... and other collaborators

Completed

Comparison of Home- vs. Gym-based Exercise Delivery Modes (UPSIDE DOWNS)

Vascular Stiffness | Cardiorespiratory Fitness

Portugal
Associacao para Investigacao e Desenvolvimento...
Cardiovascular Center of the University of Lisbon; Unidade Local de Saúde Santa...

Enrolling by invitation

SPIRIT: Study of the Patency of Spinal aRteries After the STABILISE Technique (SPIRIT)

Aortic Dissection | Spinal Cord Ischemia

Portugal
Universidade do Porto

Recruiting

National Varicose Vein Study - Portugal

Chronic Venous Insufficiency

Portugal
University Institute of Maia
University of Southern Denmark

Completed

Recreational Futsal for Controlled Hypertension (HyperFut)

Hypertension | Blood Pressure | Blood Pressure Disorders | Hypertension,Essential

Portugal
Ipsen

Completed

Botulinum Toxin A Associated Costs in the Treatment of Upper Limb Spasticity Post Stroke (P_Dysport_CS)

Upper Limb Spasticity Post-Stroke

Portugal
Association for Innovation and Biomedical Research...
Fundação para a Ciência e a Tecnologia

Completed

Characterization of Retinal Vascular Disease in Eyes With Mild to Moderate NPDR in Diabetes Type 2 (CORDIS)

NPDR - Non Proliferative Diabetic Retinopathy

Portugal
Aveiro University
University Institute of Maia; Cardiology Department, Hospital Infante D. Pedro... and other collaborators

Completed

The Role of Exercise Training in the Treatment of Resistant Hypertension (EnRIcH)

Resistant Hypertension

Portugal
Hospital de Santa Maria, Portugal

Unknown

Mesotherapy In Lateral Epicondylitis (MILES)

Lateral Epicondylitis

Portugal
Universidade da Madeira

Recruiting

Comparing Personalized and Adaptive Cognitive Training Methods Following Stroke

Stroke | Cognitive Training

Portugal
Universidade do Porto

Completed

Polidocanol Foam VS Artery Ligation in Hemorrhoidal Disease

Hemorrhoids

Portugal
Instituto de Medicina Molecular João Lobo Antunes
Fundação para a Ciência e a Tecnologia

Completed

Impact of Physical Activity in Vascular Cognitive Impairment ( AFIVASC ) (AFIVASC)

Vascular Cognitive Impairment

Portugal
Instituto Politécnico de Setúbal. Escola Superior...
Centro Hospitalar Lisboa Ocidental; Universidade de Lisboa - Faculdade Letras; Centro Hospitalar de Setúbal E.P.E... and other collaborators

Unknown

Effectiveness of Exercise and Patient-centred Education on Fibromyalgia

Fibromyalgia

Portugal
University of Coimbra

Completed

Simulation Training For Invasive Cardiovascular Procedures (Heart-SIMS1)

Coronary Artery Disease

Portugal

Clinical Trials on Macular Degeneration Advanced in Portugal

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