Clinical Trials on Malignant Bone Neoplasm

Total 127371 results

University of Chicago
Stand Up To Cancer

Recruiting

Novel Outreach Methods to Increase Enrollment to Early Phase Clinical Trials

Cancer | Malignant Neoplasm | Malignancy

United States
University of Roma La Sapienza

Unknown

Primary Pain Palliation in Bone Metastases Treated With Magnetic Resonance-guided Focused Ultrasound

Secondary Malignant Neoplasm of Bone

Italy
Philips Healthcare

Completed

Pilot Study for Palliation of Pain in Bone Metastases by MR-HIFU

Secondary Malignant Neoplasm of Bone

France
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

18F-FDG PET-MRI for Planning and Follow-Up of Patients With Spine Tumors Treated With Spine Stereotactic Radiosurgery

Metastatic Malignant Neoplasm in the Bone | Metastatic Malignant Neoplasm

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Supervised Exercise in Improving Physical Fitness Before Surgery in Patients With Resectable Bone Cancer

Malignant Bone Neoplasm

United States
University of Edinburgh
NHS Lothian

Completed

Thermal Testing in Bone Pain (TiBoP) (TiBoP)

Pain | Toxicity Due to Radiotherapy | Cancer Induced Bone Pain | Secondary Malignant Neoplasm of Bone

United Kingdom
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Dual Energy Computed Tomography (CT) in Finding Bone Metastases in Patients With Cancer

Malignant Neoplasm | Metastatic Malignant Neoplasm to the Bone

United States
Massachusetts General Hospital
National Cancer Institute (NCI)

Completed

Effect of High Doses of Radiation on Bone Structure and Metabolism

Malignant Bone Tumors

United States
M.D. Anderson Cancer Center

Withdrawn

BAY1895344 and Copanlisib for the Treatment of Molecularly Selected Patients With Advanced Solid Tumors

Locally Advanced Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Metastatic Malignant Neoplasm in the Bone
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Recruiting

Palliative Radiation Therapy in Reducing Pain in Patients With Bone Metastasis

Pain | Metastatic Malignant Neoplasm in the Bone | Malignant Neoplasm

United States
Henan Cancer Hospital

Not yet recruiting

Application of Douyin in Perioperative Period of Malignant Tumor Patients

Perioperative Period | Malignant Tumor of Bone
Rutgers, The State University of New Jersey

Terminated

Correlation of Bispectral Index Score and Total Intravenous Anesthesia (TIVA)

Benign/Malignant Neoplasm | Long Bone Fracture

United States
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Unknown

Study of Anlotinib in Patients With Primary Malignant Bone Tumors

Neoplasm of Bone

China
Royal Marsden NHS Foundation Trust
University College London Hospitals; University of Southampton; St George's University... and other collaborators

Completed

Information Needs Around Parenteral nUTrition in Cancer (INPUT)

Neoplasms | Cancer | Tumor | Malignant Neoplasm | End Stage Cancer | Malignancy | Terminal Cancer

United Kingdom
Instituto Materno Infantil Prof. Fernando Figueira

Unknown

Laser Therapy Prevents Mucositis Oral in Chemotherapy for Bone Marrow Transplantation? (lasertherapy)

Oral Mucositis | Effects of Chemotherapy | Malignant Neoplasm of Bone Marrow

Brazil
OHSU Knight Cancer Institute
Oregon Health and Science University

Available

Bone Marrow Transplantation Using CD34-Selected Stem Cells From Related or Unrelated Donors in Treating Participants With Cancer or Other Disorders

Malignant Neoplasm | Hematopoietic Cell Transplantation Recipient | Benign Neoplasm | Bone Marrow Transplantation Recipient

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Brain Imaging Changes Following Proton Therapy for Pediatric Primary Central Nervous System and Base of Skull Tumors

Malignant Central Nervous System Neoplasm | Malignant Skull Base Neoplasm

United States
Dana-Farber Cancer Institute

Completed

Image-guided Cryoablation of Head, Neck and Spine Tumors

Head and Neck Neoplasms | Malignant Neoplasm of Vertebral Column

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Donor Natural Killer Cells, Cyclophosphamide, and Etoposide in Treating Children and Young Adults With Relapsed or Refractory Solid Tumors

Refractory Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Recurrent Cutaneous Melanoma | Recurrent Malignant Female Reproductive System Neoplasm | Refractory Malignant Female Reproductive System Neoplasm | Recurrent Lip and Oral Cavity Carcinoma | Recurrent Malignant Endocrine... and other conditions

United States
Henan Cancer Hospital

Not yet recruiting

Application of 3D Printed Prosthesis in Limb Salvage Surgery for Bone Tumors

Malignant Tumor

China
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

NaF PET/MRI Evaluation for Bone Metastases in Breast Cancer

Malignant Neoplasm of Breast TNM Staging Distant Metastasis (M) | Untreated Bone Metastases

United States
National Cancer Institute, Egypt

Completed

Dorsal Root Ganglion Thermal Radiofrequency Versus Pulsed Radiofrequency for Metastatic Pain in Thoracic Vertebral Body

Bone Neoplasm,Malignant Vertebral Column Thoracic Secondary

Egypt
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Cement Augmentation in Preventing Vertebral Body Compression Fracture Following Spine Stereotactic Radiosurgery in Patients With Solid Tumors and Spinal Metastases

Metastatic Malignant Solid Neoplasm | Metastatic Malignant Neoplasm in the Spine

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Serial Magnetic Resonance Imaging for the Prediction of Radiation-Induced Changes in Normal Tissue of Patients With Oral Cavity or Skull Base Tumors

Osteoradionecrosis | Malignant Skull Base Neoplasm | Malignant Oral Cavity Neoplasm

United States
M.D. Anderson Cancer Center
Gateway for Cancer Research; James B. and Lois R. Archer Charitable Foundation

Recruiting

Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary Metastases

Malignant Neoplasms of Female Genital Organs | Malignant Neoplasms of Lip Oral Cavity and Pharynx | Melanoma and Other Malignant Neoplasms of Skin | Malignant Neoplasm of Bone and Articular Cartilage | Malignant Neoplasms of Independent (Primary) Multiple Sites | Malignant Neoplasm of Male... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Terminated

Telemonitoring After Surgery to Preserve Limb Function in Optimizing Mobility in Cancer Survivors With Skeletal Metastases

Bone Metastases | Cancer Survivor | Metastatic Malignant Neoplasm in the Bone

United States
Peking University People's Hospital

Recruiting

Narlumosbartmab Combined With Neoadjuvant Chemotherapy in Bone-derived Malignancies With Osteolytic Lesions and Multinucleated Giant Cells

Malignant Bone Tumor

China
M.D. Anderson Cancer Center
Eisai Inc.

Withdrawn

Lenvatinib and Capecitabine in Patients With Advanced Malignancies

Advanced Cancer | Malignant Neoplasms of Female Genital Organs | Malignant Neoplasm of Breast | Malignant Neoplasms of Ill-defined Secondary and Unspecified Sites | Malignant Neoplasms of Lip Oral Cavity and Pharynx | Malignant Neoplasms of Independent (Primary) Multiple Sites | Malignant Neoplasms... and other conditions
University of Illinois at Chicago
Millennium Pharmaceuticals, Inc.

Completed

Phase I Study of MLN8237 and Pazopanib in Patients With Solid Tumors

Melanoma | Head and Neck Neoplasms | Malignant Neoplasm of Breast | Malignant Neoplasm of Thorax | CNS Malignancy | Malignant Neoplasm of Gastrointestinal Tract | Genitourinary Neoplasms Malignancy and Gender Unspecified

United States
National Cancer Institute (NCI)

Active, not recruiting

Combination Chemotherapy With or Without Ganitumab in Treating Patients With Newly Diagnosed Metastatic Ewing Sarcoma

Metastatic Malignant Neoplasm in the Bone | Peripheral Primitive Neuroectodermal Tumor of Soft Tissues | Metastatic Malignant Neoplasm in the Lung | Metastatic Ewing Sarcoma | Metastatic Malignant Neoplasm in the Bone Marrow | Metastatic Peripheral Primitive Neuroectodermal Tumor of Bone

United States, Canada, Puerto Rico
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Muscadine Grape Skin Extract in Treating Patients With Malignancy That Is Metastatic or Cannot Be Removed by Surgery

Metastatic Malignant Neoplasm | Unresectable Malignant Neoplasm | Advanced Malignant Neoplasm

United States
University of Utah

Active, not recruiting

Salvage Oligometastasectomy and Radiation Therapy in Recurrent Prostate Cancer (SOAR)

Prostate Adenocarcinoma | Metastatic Malignant Neoplasm in the Bone | Metastatic Malignant Neoplasm in the Lymph Nodes | Recurrent Prostate Carcinoma | Oligometastasis | PSA Failure

United States
Centre Hospitalier Universitaire de Saint Etienne
Institut de Cancérologie de la Loire; Institut de Recherche Biomedicale des...

Terminated

Validation of Radio-induced Damage Biomarkers (BIOM-DRI)

Bone Metastasis | Malignant Hemopathy

France
National Cancer Institute (NCI)

Active, not recruiting

Testing the Sequential Combination of the Anti-cancer Drugs Olaparib Followed by Adavosertib (AZD1775) in Patients With Advanced Solid Tumors With Selected Mutations and PARP Resistance, STAR Study

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
Lucid Lane, Inc
M.D. Anderson Cancer Center

Recruiting

Digital and Behavioral Tele-Health Tapering Program for Lowering Dependence on Opioids in Patients Undergoing Surgery

Malignant Solid Neoplasm | Malignant Thoracic Neoplasm | Malignant Head and Neck Neoplasm | Malignant Abdominal Neoplasm

United States
National Cancer Institute (NCI)

Active, not recruiting

Trametinib and Navitoclax in Treating Patients With Advanced or Metastatic Solid Tumors

Refractory Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of an Anti-cancer Drug, Copanlisib, to the Usual Immunotherapy (Nivolumab With or Without Ipilimumab) in Patients With Advanced Solid Cancers That Have Changes in the Following Genes: PIK3CA and PTEN

Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States, Canada
National Cancer Institute (NCI)

Recruiting

Testing the Combination of Two Anti-cancer Drugs, Peposertib (M3814) and M1774 for Advanced Solid Tumors

Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Combination of the Anti-cancer Drugs Copanlisib, Olaparib, and MEDI4736 (Durvalumab) in Patients With Advanced Solid Tumors With Selected Mutations

Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
National Cancer Institute (NCI)

Completed

Testing the Addition of the Anti-Cancer Drug Talazoparib to the Combination of Carboplatin and Paclitaxel for the Treatment of Advanced Cancer

Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
National Cancer Institute (NCI)

Completed

Imatinib Mesylate in Treating Patients With Advanced Soft Tissue Sarcoma or Bone Sarcoma

Sarcoma | Childhood Malignant Fibrous Histiocytoma of Bone

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Phase I/II Randomized Study of NBTXR3 Activated by Abscopal or RadScopal Radiation in Combination With Immunotherapy (Anti-PD-1/L-1) for Patients With Advanced Solid Malignancies

Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Metastatic Malignant Neoplasm in the Liver | Metastatic Malignant Neoplasm in the Lung

United States
Gustave Roussy, Cancer Campus, Grand Paris

Recruiting

Long Term Brain Toxicity of Chemotherapy in Patients Treated for a Bone TumorDuring Childhood or Adolescence (OSE)

Adults Treated During Childhood or Adolescence for a Malignant Bone Tumor (Osteosarcoma and Ewing Sarcoma)

France
M.D. Anderson Cancer Center

Active, not recruiting

Avelumab and M6620 for the Treatment of DDR Deficient Metastatic or Unresectable Solid Tumors

Refractory Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
St. Jude Children's Research Hospital
Genentech, Inc.

Completed

A Study of Bevacizumab in Combination With Chemotherapy for Treatment of Osteosarcoma

Osteosarcoma | Malignant Fibrous Histiocytoma (MFH) of Bone

United States
National Cancer Institute (NCI)

Recruiting

Study of Chemotherapy Plus Ipatasertib for People With Solid Tumors With AKT Mutations, A ComboMATCH Treatment Trial

Locally Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States, Puerto Rico
University of California, San Francisco

Completed

Integrative Palliative Care/Psycho-Oncology Telehealth Intervention in Patients With Advanced Cancer

Advanced Malignant Solid Neoplasm | Locally Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Completed

Pre-Test Genetic Education and Remote Genetic Counseling in Communicating Tumor Profiling Results to Patients With Advanced Cancer

Advanced Malignant Neoplasm | Locally Advanced Malignant Neoplasm

United States
M.D. Anderson Cancer Center

Terminated

Pevonedistat and Pembrolizumab for the Treatment of dMMR/MSI-H Metastatic or Locally Advanced Unresectable Solid Tumor

Locally Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
NRG Oncology
National Cancer Institute (NCI)

Active, not recruiting

Testing Whether Treating Breast Cancer Metastases With Surgery or High-Dose Radiation Improves Survival

Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Bone | Metastatic Malignant Neoplasm in the Lymph Nodes | Metastatic Malignant Neoplasm in the Liver | Metastatic Breast Carcinoma | Metastatic Malignant Neoplasm in the Lung and other conditions

United States, Canada, Saudi Arabia, Korea, Republic of

Clinical Trials on Malignant Bone Neoplasm

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