Clinical Trials on Malignant Glioma

Total 6834 results

M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Procarbazine and Isotretinoin in Treating Patients With Recurrent Primary Malignant Gliomas

Brain and Central Nervous System Tumors
National Cancer Institute (NCI)

Completed

Carmustine in Treating Patients With Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

United States
National Cancer Institute (NCI)

Completed

Brachytherapy in Treating Patients With Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

United States
National Cancer Institute (NCI)

Completed

O6-Benzylguanine and Carmustine Implants in Treating Patients With Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

United States
National Cancer Institute (NCI)

Completed

Alanosine in Treating Patients With Progressive or Recurrent Malignant Gliomas

Brain and Central Nervous System Tumors

United States
National Cancer Institute (NCI)

Completed

Karenitecin in Treating Patients With Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

United States
Massachusetts General Hospital

Not yet recruiting

ASCENT Intervention for Brain Tumor Patients

Glioma | Coping Skills | Distress, Emotional | Malignant Brain Tumor

United States
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

18F-DOPA-PET in Planning Surgery in Patients With Gliomas

Malignant Glioma | Recurrent Brain Neoplasm

United States
Rush University Medical Center

Terminated

Topotecan and Thalidomide in Treating Patients With Recurrent or Refractory Malignant Glioma

Brain and Central Nervous System Tumors

United States
Jonsson Comprehensive Cancer Center

Completed

Vaccine Therapy in Treating Young Patients Who Are Undergoing Surgery for Malignant Glioma

Brain and Central Nervous System Tumors

United States
Northwestern University
CTI BioPharma; Cephalon

Unknown

Arsenic Trioxide, Temozolomide, and Radiation Therapy in Treating Patients With Malignant Glioma That Has Been Removed By Surgery

Brain and Central Nervous System Tumors

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Fenretinide in Treating Patients With Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Gene Therapy in Treating Patients With Recurrent Malignant Gliomas

Brain and Central Nervous System Tumors

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Irinotecan in Treating Patients With Progressive or Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Temozolomide Plus Irinotecan in Treating Patients With Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

United States
Duke University
National Cancer Institute (NCI)

Completed

Irinotecan Plus Temozolomide in Treating Patients With Recurrent Primary Malignant Glioma

Brain and Central Nervous System Tumors

United States
Duke University
National Cancer Institute (NCI)

Completed

Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) With Bevacizumab and Irinotecan for Malignant Glioma

Brain and Central Nervous System Tumors

United States
Northwestern University
Millennium Pharmaceuticals, Inc.

Completed

Presurgery Bortezomib for Recurrent Malignant Gliomas Followed by Postop Bortezomib & Temozolomide

Brain and Central Nervous System Tumors

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Temozolomide in Treating Patients With Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

United States
Duke University
National Cancer Institute (NCI)

Completed

Imatinib Mesylate and Temozolomide in Treating Patients With Malignant Glioma

Brain and Central Nervous System Tumors

United States
Northwestern University
Vion Pharmaceuticals

Terminated

VNP40101M and Temozolomide in Treating Patients With Progressive or Relapsed Malignant Glioma

Brain and Central Nervous System Tumors

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

Carmustine Implants and O(6)-Benzylguanine in Treating Children With Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

United States
National Cancer Institute (NCI)

Completed

Atrasentan in Treating Patients With Progressive or Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

United States
Samus Therapeutics, Inc.

Terminated

Study of Icapamespib (PU-AD) in Patients With Recurrent Malignant Glioma (Glio)

Recurrent Glioblastoma Multiforme (GBM) | Grade 3 Isocitrate Dehydrogenase (IDH) Wildtype Astrocytoma | Grade 3 or 4 Astrocytoma | Glioblastoma Surgery

United States
Jonsson Comprehensive Cancer Center

Completed

Erlotinib and Sirolimus in Treating Patients With Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

United States
NCIC Clinical Trials Group

Completed

SarCNU in Treating Patients With Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

Canada
Dana-Farber Cancer Institute
National Cancer Institute (NCI); Celgene; Schering-Plough

Completed

Thalidomide, Celecoxib, and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Malignant Glioma

Brain and Central Nervous System Tumors

United States
Herbert Irving Comprehensive Cancer Center

Unknown

Temozolomide in Treating Patients With Recurrent or Progressive Malignant Glioma

Brain and Central Nervous System Tumors

United States
Barrett Cancer Center

Completed

Internal Radiation Therapy Plus Carmustine Implants in Treating Patients With Recurrent or Refractory Malignant Glioma

Brain and Central Nervous System Tumors

United States
New Approaches to Brain Tumor Therapy Consortium
National Cancer Institute (NCI)

Completed

Efaproxiral Plus Carmustine in Treating Patients With Progressive or Recurrent Malignant Glioma

Brain and Central Nervous System Tumors

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Withdrawn

Immunotoxin Therapy in Treating Children With Recurrent Malignant Gliomas

Brain and Central Nervous System Tumors
Abramson Cancer Center of the University of Pennsylvania
United States Department of Defense

Completed

Skull Base and Low Grade Glioma Neurocognitive Magnetic Resonance Imaging (MRI) Study

Glioma | Radiotherapy | Malignancy

United States
Assistance Publique - Hôpitaux de Paris
Association de Neuro-Oncologues d'Expression Francaise

Active, not recruiting

gliomasPCV Only in 1p/19q Codeleted Anaplastic Gliomas (POLCA)

Anaplastic Gliomas With 1p/19q Codeletion

France
University of Colorado, Denver

Withdrawn

Fluorescein vs. iMRI in Resection of Malignant High Grade Glioma

Glioblastoma Multiforme | Anaplastic Astrocytoma | High Grade Malignant Neoplasm

United States
National Cancer Institute (NCI)

Active, not recruiting

Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial)

Malignant Glioma | Recurrent Childhood Ependymoma | Rhabdoid Tumor | Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Recurrent Hepatoblastoma | Recurrent Langerhans Cell Histiocytosis | Recurrent Malignant Solid Neoplasm | Recurrent Medulloblastoma | Recurrent Neuroblastoma | Recurrent... and other conditions

United States, Puerto Rico
University Hospital, Strasbourg, France

Recruiting

Pediatric Low Grade Glioma - MEKinhibitor TRIal vs Chemotherapy (PLGG - MEKTRIC)

Pleomorphic Xanthoastrocytoma | Grade 1 Glioma | Mixed Glio-neuronal Tumors

France
Huashan Hospital

Completed

Efficacy and Tolerability of Cisplatin Plus Alternating Weekly Temozolomide in Recurrent High-grade Gliomas

High-grade Gliomas

China
Jasper Gerritsen
Massachusetts General Hospital; Universitaire Ziekenhuizen KU Leuven; University... and other collaborators

Recruiting

The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201) (SUPRAMAX)

Glioblastoma | Brain Neoplasms | Astrocytoma, Grade III | High-grade Glioma | Astrocytoma, Grade IV | Glioblastoma, IDH-mutant | Glioblastoma, IDH-wildtype | Glioblastoma Multiforme, Adult | Brain Neoplasm, Primary | Brain Neoplasm, Malignant | Astrocytoma, Malignant | Brain Neoplasms, Adult

United States, Germany, Belgium, Switzerland, Netherlands
NewLink Genetics Corporation

Completed

Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain Tumors

Glioma | Glioblastoma Multiforme | Gliosarcoma | Malignant Brain Tumor

United States
National Cancer Institute (NCI)
Children's Oncology Group

Active, not recruiting

Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial

Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Recurrent Ependymoma | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Histiocytic and Dendritic Cell Neoplasm | Recurrent Langerhans Cell Histiocytosis | Recurrent Lymphoma | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant... and other conditions

United States, Puerto Rico, Australia
Hospital Sant Joan de Deu
Fundació Sant Joan de Déu; Spanish National Health System

Completed

Irinotecan in Combination With Cisplatin in Pediatric Patients With Unfavorable Prognosis Gliomas

Pediatric High Risk Gliomas

Spain
Gregory K. Friedman, MD
Memorial Sloan Kettering Cancer Center; United States Department of Defense; Food... and other collaborators

Completed

HSV G207 Alone or With a Single Radiation Dose in Children With Progressive or Recurrent Supratentorial Brain Tumors

Glioblastoma | Malignant Glioma | PNET | Anaplastic Astrocytoma | Embryonal Tumor | Supratentorial Neoplasms, Malignant | Cerebral Primitive Neuroectodermal Tumor

United States
National Cancer Institute (NCI)

Completed

Entinostat in Treating Pediatric Patients With Recurrent or Refractory Solid Tumors

Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Recurrent Lymphoma | Recurrent Malignant Solid Neoplasm | Recurrent Primary Central Nervous System Neoplasm | Refractory Primary Central Nervous System Neoplasm | Brain Stem Neoplasm | Pineal Region Neoplasm | Recurrent Visual Pathway Glioma | Refractory Visual Pathway Glioma

United States
Lee's Pharmaceutical Limited

Unknown

Phase I Clinical Study of Oral TG02 Capsule in the Treatment of Recurrent / Progressive High-grade Glioma Patients

High-grade Gliomas

China
University of Louisville

Terminated

Phase I/II: Decitabine/Vaccine Therapy in Relapsed/Refractory Pediatric High Grade Gliomas/Medulloblastomas/CNS PNETs

Neuroectodermal Tumors, Primitive | Medulloblastoma | Gliomas

United States
Burzynski Research Institute

Completed

Antineoplaston Therapy in Treating Patients With Brain Stem Glioma

Brain Stem Gliomas

United States
Assistance Publique - Hôpitaux de Paris

Completed

Treatment With AZD4547 for Recurrent Malignant Glioma Expressing FGFR-TACC Gene Fusion" (TARGET)

Recurrent IDHwt Gliomas With FGFR3-TACC3 Fusion | Recurrent IDHwt Gliomas With FGFR1-TACC1 Fusion

France
National Cancer Institute (NCI)

Active, not recruiting

Testing the Sequential Combination of the Anti-cancer Drugs Olaparib Followed by Adavosertib (AZD1775) in Patients With Advanced Solid Tumors With Selected Mutations and PARP Resistance, STAR Study

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
Northwell Health

Recruiting

Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM

Glioblastoma | Brain Cancer | Glioblastoma Multiforme | GBM | Glioma, Malignant | Glioblastoma, IDH-wildtype | Glioblastoma Multiforme, Adult

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI); Weill Medical College of Cornell University; Schering-Ploug...

Completed

Temozolomide in Treating Patients With Recurrent Glioblastoma Multiforme or Other Malignant Glioma

Brain and Central Nervous System Tumors

United States

Clinical Trials on Malignant Glioma

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CROs in Portugal

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