Clinical Trials on Metabolism, Inborn Errors in Netherlands

Total 2123 results

Pfizer

Completed

Study Evaluating the Safety,Tolerability and Efficacy of PF-04360365 in Adults With Probable Cerebral Amyloid Angiopathy

Cerebral Amyloid Angiopathy

Canada, United States, Netherlands, France, United Kingdom
Maastricht University Medical Center

Recruiting

Qualitative Study in Patients With Genodermatoses and Healthcare Professionals on Reproductive Counselling

Quality of Life | Tuberous Sclerosis | Basal Cell Nevus Syndrome | Cutis Laxa | Epidermolysis Bullosa | Ichthyosis | Ectodermal Dysplasia | Albinism | Birt-Hogg-Dube Syndrome | Palmoplantar Keratoses

Netherlands
Maastricht University Medical Center

Enrolling by invitation

Reproductive Options in Inherited Skin Diseases (REPRO-ISD)

Tuberous Sclerosis | Basal Cell Nevus Syndrome | Cutis Laxa | Epidermolysis Bullosa | Ichthyosis | Ectodermal Dysplasia | Albinism | Xeroderma Pigmentosum | Birt-Hogg-Dube Syndrome | Palmoplantar Keratoses

Netherlands
bluebird bio

Completed

A Clinical Study to Assess the Efficacy and Safety of Gene Therapy for the Treatment of Cerebral Adrenoleukodystrophy (CALD)

Cerebral Adrenoleukodystrophy (CALD)

United States, France, Germany, Italy, Netherlands, United Kingdom
Radboud University Medical Center
Dutch Kidney Foundation

Recruiting

Salt Supplementation in Gitelman Syndrome

Gitelman Syndrome

Italy, Netherlands
Minoryx Therapeutics, S.L.

Active, not recruiting

A Clinical Study to Evaluate the Efficacy and Safety of MIN-102 (IMP) in Male AMN Patients. (Advance)

Adrenoleukodystrophy

Spain, United States, Hungary, France, Germany, Italy, Netherlands, United Kingdom
Neurocrine Biosciences

Active, not recruiting

Global Safety and Efficacy Registration Study of Crinecerfont for Congenital Adrenal Hyperplasia (CAHtalyst)

Congenital Adrenal Hyperplasia

United States, Spain, Belgium, Austria, Bulgaria, Canada, Czechia, France, Germany, Greece, Israel, Italy, Netherlands, Poland, Portugal, Serbia, Sweden, United Kingdom
Spruce Biosciences

Active, not recruiting

A Ph2b to Evaluate Clinical Efficacy and Safety of Tildacerfont in Adult CAH

Congenital Adrenal Hyperplasia

United States, Australia, Brazil, Canada, Denmark, Estonia, Germany, Ireland, Italy, Korea, Republic of, Latvia, Lithuania, Netherlands, Poland, Romania, Spain, Sweden, Switzerland, Turkey, United Kingdom
Alnylam Pharmaceuticals

Active, not recruiting

HELIOS-A: A Study of Vutrisiran (ALN-TTRSC02) in Patients With Hereditary Transthyretin Amyloidosis (hATTR Amyloidosis)

Transthyretin Amyloidosis | Amyloidosis, Hereditary

United States, Argentina, Australia, Belgium, Brazil, Bulgaria, Canada, Cyprus, France, Germany, Greece, Italy, Japan, Korea, Republic of, Malaysia, Mexico, Netherlands, Portugal, Spain, Sweden, Taiwan, United Kingdom
dr. Laura C. G. de Graaff-Herder

Not yet recruiting

Growing up With the Young Endocrine Support System (YESS!) (YESS)

Congenital Adrenal Hyperplasia | Hypogonadotropic Hypogonadism | Growth Hormone Deficiency | Turner Syndrome | Addison's Disease | Klinefelter Syndrome | Combined Pituitary Hormone Deficiency | Androgen Insensitivity Syndrome | Thyroid Dysgenesis

Spain, United Kingdom, Belgium, Netherlands
Maastricht University Medical Center

Completed

VERION Versus Conventional, Manual Ink-marking in Toric IOL Implantation

Astigmatism

Netherlands
Maastricht University Medical Center

Active, not recruiting

Effect of Matrices on Serum Fructose.

Fructose Metabolism Disorder

Netherlands
Unilever R&D
Maastricht University

Completed

Continuous Glucose Monitoring During Diets That Differ in Glycemic Load (GLOW)

Glucose Metabolism Disorders

Netherlands
Medical Research Foundation, The Netherlands
Medtronic

Completed

Accuracy and Safety of Real Time Continuous Glucose Monitoring Before, During and After Surgery (GluContinu)

Glucose Metabolism Disorders | Perioperative Care

Netherlands
Maastricht University Medical Center
DSM Food Specialties

Recruiting

Impact of Canola Protein Processing on Plasma Amino Acid Responses (CANOLAA)

Protein Metabolism Disorder

Netherlands
Wageningen University and Research
Asahimatsu Foods

Completed

Cholesterol Effects of Kori-tofu Proteins (CHOKO)

Lipid Metabolism Disorders

Netherlands
bluebird bio

Terminated

Observational Study to Evaluate Allogeneic HSCT Outcomes for Cerebral Adrenoleukodystrophy (CALD)

Cerebral Adrenoleukodystrophy (CALD) | Adrenoleukodystrophy (ALD) | X-Linked Adrenoleukodystrophy (X-ALD)

United States, United Kingdom, Argentina, Canada, Germany, Italy, Netherlands
bluebird bio

Active, not recruiting

Long-term Follow-up of Participants With Cerebral Adrenoleukodystrophy Who Were Treated With Lenti-D Drug Product

Cerebral Adrenoleukodystrophy (CALD) | Adrenoleukodystrophy (ALD) | X-Linked Adrenoleukodystrophy (X-ALD)

United States, Argentina, Australia, Brazil, France, Germany, Netherlands, United Kingdom, Italy
Maastricht University Medical Center
Center for Translational Molecular Medicine

Completed

Cross-over Study on Effect of Lipid Lowering by Acipimox on Cardiac and Skeletal Muscle Mitochondrial Function (ACP)

Diabetes Mellitus, Type 2 | Cardiomyopathy, Dilated

Netherlands
Leiden University Medical Center
Dutch Diabetes Research Foundation

Completed

Metabolic Effects of Subchronic Dopamine D2 Receptor Blockade by Haloperidol in Healthy Humans

Insulin Resistance | Dyslipidemia

Netherlands
Maastricht University Medical Center
Abbott Medical Optics

Completed

A Randomised Evaluation of Visual Function After Bilateral Implantation of Two Types of Presbyopia-correcting IOLs

Cataract | Presbyopia

Netherlands
Yale University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Academisch...

Recruiting

Metabolic Heterogeneity Underlying Hypertriglyceridemia: Hepatic Triglyceride Biosynthesis in Humans With Different Insulin Resistance Phenotypes

Insulin Resistance | Hypertriglyceridemia

Netherlands
Pfizer

Completed

Transthyretin Amyloidosis Outcome Survey (THAOS) (THAOS)

Transthyretin Amyloidosis | Transthyretin Gene Mutations

United States, France, Spain, Taiwan, Israel, Korea, Republic of, Denmark, Canada, Netherlands, Japan, Sweden, Brazil, Mexico, Argentina, Portugal, Belgium, Bulgaria, Cyprus, Germany, Italy, Malaysia, Romania, Saudi Arabia, Turkey, United...
Leiden University Medical Center
Dutch Diabetes Research Foundation

Completed

Metabolic Effects of Subchronic Dopamine D2 Receptor Blockade by Antipsychotic Drugs in Healthy Humans

Insulin Resistance | Dyslipidemia

Netherlands
Maastricht University Medical Center
Bioriginal Europe / Asia B.V.

Completed

Stearidonic Acid and Lipid Metabolism

Lipid Metabolism Disorders

Netherlands
Maastricht University Medical Center
Ministry of Education, Culture and Science

Unknown

Human Brown Adipose Tissue and Mitochondrial Respiration

Obesity | Aging | Mitochondrial Metabolism Disorders | Adipose Tissue, Brown

Netherlands
Maastricht University Medical Center
Unilever R&D

Completed

Alpha-linolenic Acid and Blood Pressure (VASALA)

Hypertension | Lipid Metabolism Disorders

Netherlands
Maastricht University Medical Center
DSM Nutritional Products, Inc.

Completed

Resveratrol and Serum Apo A-I

Dyslipidemia

Netherlands
UMC Utrecht

Completed

Effects of Ezetimibe on Postprandial Hyperlipidemia and Endothelial Function

Metabolic Syndrome

Netherlands
Maastricht University Medical Center
Nederlandse Zuivel Organisatie

Completed

Effect of Feeding Frequency on Glucose and Insulin Metabolism and Substrate Partitioning in Impaired Glucose Tolerant (IGT) Men

Glucose Intolerance

Netherlands
AstraZeneca

Completed

The Effect of Rosuvastatin on Aortic Stiffness in Hemodialysis Patients in the AURORA Study

Hypercholesterolemia

Netherlands
Maastricht University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Astigmatism Management in Cataract Surgery With the AcrySof Toric Intraocular Lens

Astigmatism

Netherlands
Akros Pharma Inc.

Completed

Safety and Efficacy Study of JTT-705 in Combination With Simvastatin 40 mg in Patients With Low High-Density Lipoprotein (HDL) Levels

Dyslipidemia

Netherlands
Akros Pharma Inc.

Completed

Safety and Efficacy Study of JTT-705 in Combination With Atorvastatin 20 mg in Patients With Low High-Density Lipoprotein (HDL) Levels

Dyslipidemia

Netherlands
Santaris Pharma A/S

Terminated

Multiple Ascending Dose Study of SPC5001 in Treatment of Healthy Subjects and Subjects With FH

Hypercholesterolemia

Netherlands
Alnylam Pharmaceuticals

Completed

APOLLO: The Study of an Investigational Drug, Patisiran (ALN-TTR02), for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis

Amyloid Neuropathies | Amyloid Neuropathies, Familial | TTR-mediated Amyloidosis | Amyloidosis, Hereditary | Amyloidosis, Hereditary, Transthyretin-Related | Familial Amyloid Polyneuropathies

United States, Canada, Argentina, Australia, Bulgaria, Cyprus, Italy, Japan, Malaysia, Mexico, Netherlands, Portugal, Spain, Sweden, Germany, France, Brazil, Turkey, Korea, Republic of, Taiwan, United Kingdom
Maastricht University Medical Center

Not yet recruiting

Acute Microbial Switch

Hyperinsulinism | Insulin Sensitivity | Glucose Metabolism Disorders (Including Diabetes Mellitus)

Netherlands
Nutricia Research

Completed

Glucose Response to a Formula for Patients at Risk of Hypoglycaemia (EFFECT)

Postprandial Hypoglycemia

Netherlands
Maastricht University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development

Completed

Long Term Effects of Plant Sterol and Stanol Esters (LTS)

Hypercholesterolemia

Netherlands
Utrecht Institute for Pharmaceutical Sciences
Harvard University; Scientific Institute for Dutch Pharmacists, The Netherlands and other collaborators

Completed

A Community Pharmacist-led Intervention to Improve Adherence to Lipid-lowering Treatment

Hypercholesterolemia

Netherlands
Alnylam Pharmaceuticals

Active, not recruiting

APOLLO-B: A Study to Evaluate Patisiran in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR Amyloidosis With Cardiomyopathy)

Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

United States, Australia, Brazil, Bulgaria, France, Italy, Japan, Mexico, Netherlands, Taiwan, United Kingdom, Belgium, Czechia, Denmark, New Zealand, Sweden, Korea, Republic of, Argentina, Chile, Hong Kong, Portugal
Maastricht University Medical Center

Completed

Role of Angiotensin II in Insulin-induced Microvascular Activity

Insulin Sensitivity | Microcirculation

Netherlands
Khondrion BV
Julius Clinical; ProPharma Group; Certara

Completed

The KHENEREXT Study

Mitochondrial Diseases | Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation | Maternally Inherited Diabetes and Deafness (MIDD) | Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke Like Episodes (MELAS) | Chronic Progressive External Ophthalmoplegia (CPEO)

Netherlands, Denmark, United Kingdom, Germany
Alnylam Pharmaceuticals

Active, not recruiting

HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

United States, Poland, Argentina, Australia, Belgium, France, Germany, Japan, Netherlands, Portugal, Spain, Sweden, United Kingdom, Canada, Czechia, Denmark, Hungary, Ireland, Norway, Korea, Republic of, Austria, Croatia, Israel, Latvia, Lithuan... and more
Rijnstate Hospital

Completed

FGF-23 Suppressibility by Calcitonin

Hypophosphatemia

Netherlands
Maastricht University Medical Center
Top Institute Food and Nutrition

Completed

Body Weight and Vascular Function

Obesity | Metabolic Syndrome

Netherlands
Assiut University

Completed

IVL and RA in Treatment of Balloon-crossable Severely Calcified Coronary Lesions

Coronary Calcification

Netherlands
Maastricht University Medical Center

Recruiting

Alternating Energy Intake and Blood Fat Content After a Meal

Glucose Metabolism | Abdominal Obesity | Lipid Metabolism | Postprandial Lipemia

Netherlands
Maastricht University Medical Center

Completed

Gut Flora and Lipid Metabolism

Hypercholesterolemia

Netherlands
Maastricht University Medical Center
Raisio Group

Completed

Plant Stanols and Gene Expression Profile

Hypercholesterolemia

Netherlands

Clinical Trials on Metabolism, Inborn Errors in Netherlands

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