Clinical Trials on Metastatic

Total 9359 results

Gustave Roussy, Cancer Campus, Grand Paris

Completed

Study of the Intra-patient Variability of the Quantitative Parameters of Tumor Perfusion Evaluated With Ultrasound Contrast (VARIA-DCE-US)

GIST Metastatic Cancer | Breast Metastatic Cancer | Kidney Metastatic Cancer | Colon Metastatic Cancer | Rectal Metastatic Cancer

France
Memorial Sloan Kettering Cancer Center

Completed

Study of Palliative Radiation Therapy vs. no Palliative Radiation Therapy for Patients With High Risk Bone Metastases That Are Not Causing Significant Pain

Metastatic Solid Tumors of Metastatic Disease

United States
David Palma

Recruiting

A Randomized Phase III Trial of Stereotactic Ablative Radiotherapy for Patients With Up to 10 Oligometastases and a Synchronous Primary Tumor. (SABR-SYNC)

Metastatic Tumor

Canada
Institut Claudius Regaud

Completed

Evaluation of an Organized Consultation "Return Home" of Patients With a Cancer (CREDO) (CREDO)

METASTATIC CANCER

France
UNICANCER

Completed

EXPRESS: EXcePtional RESponSe - Exceptional and Unexpected Response to Targeted Therapies (EXPRESS)

Metastatic Cancers

France
Duke University

Recruiting

Role of Ablative Radiotherapy in the Management of Metastatic Disease: A Patient Data Registry

Metastatic Cancer | Oligometastasis

United States
AO Innovation Translation Center
AO Foundation, AO Spine

Recruiting

Metastatic Tumor Research and Outcomes Network (MTRON)

Metastatic Spine Tumor

United States, Canada, Hungary, Australia, Germany, Italy, Japan, Netherlands, Singapore, Switzerland
Bavarian Nordic

Completed

A Phase 1 Open Label Trial of Intravenous Administration of MVA-BN-Brachyury Vaccine in Patients With Advanced Cancer

Solid Metastatic Tumor

United States
University of California, San Diego

Active, not recruiting

Checkpoint Blockade Immunotherapy Combined With Stereotactic Body Radiation in Advanced Metastatic Disease

Metastatic Cancer

United States
Institut Investigacio Sanitaria Pere Virgili
Institut Català d'Oncologia; Hospital Universitario Ramon y Cajal; Hospital Arnau... and other collaborators

Recruiting

The Impact of Radiotherapy on Oligometastatic Cancer

Metastatic Colorectal Cancer | Metastatic Lung Cancer | Metastatic Breast Cancer | Metastasis | Metastatic Prostate Cancer

Spain
Memorial Sloan Kettering Cancer Center
AstraZeneca

Recruiting

A Study of AZD1390 and Stereotactic Body Radiotherapy (SBRT) for People With Metastatic Solid Tumor Cancer

Solid Tumor | Metastatic Cancer | Metastatic Solid Tumor | Solid Tumor, Adult | Solid Carcinoma | Metastatic Tumor

United States
Centre Hospitalier Universitaire de Besancon
National Cancer Institute, France

Completed

Allogenic Immunotherapy Based on Natural Killer (NK) Cell Adoptive Transfer in Metastatic Gastrointestinal Carcinoma Treated With Cetuximab (NK-EGFR01)

Gastrointestinal Metastatic Cancer

France
AstraZeneca

Completed

Phase I Orally Administered 14C-AZD2171 in Patients With Solid Metastatic Tumors

Advanced Solid Metastatic Tumor

United Kingdom
Institut de Cancérologie de la Loire
Saint-Louis Hospital, Paris, France; Gustave Roussy, Cancer Campus, Grand Paris

Withdrawn

Phase II Trial Assessing the Efficacy of Immuno-Radiation Abscopal Effect in Patients With Metastatic Cancers (IRAM)

Metastatic Colorectal Cancer | Metastatic Breast Cancer | Metastatic Head and Neck Cancer

France
Genentech, Inc.

Active, not recruiting

Safety and Pharmacokinetics (PK) of Escalating Doses of Tiragolumab as a Single Agent and in Combination With Atezolizumab and/or Other Anti-Cancer Therapies in Locally Advanced or Metastatic Tumors

Advanced/Metastatic Tumors

Spain, United States, Korea, Republic of, Australia, France, Japan, Canada
The Cooper Health System

Completed

Observation for Patients With Asymptomatic CNS Metastatic Disease

Cancer | Metastatic Cancer

United States
Stony Brook University
The University of Texas Health Science Center at San Antonio

Recruiting

Definitive Radiation for High-Risk Spine Metastases

Metastatic Cancer | Metastatic Lung Cancer | Metastatic Breast Cancer | Metastasis | Spine Metastases | Metastatic Tumor | Metastatic Tumor of Bone | Metastatic Tumor to the Spine

United States
Abramson Cancer Center of the University of Pennsylvania

Completed

RADVAX: A Stratified Phase I Trial of Pembrolizumab With Hypofractionated Radiotherapy in Patients With Advanced and Metastatic Cancers

Metastatic Cancers

United States
Centre Leon Berard
Transgene

Completed

Immunization Strategy With Intra-tumoral Injections of Pexa-Vec With Ipilimumab in Metastatic / Advanced Solid Tumors. (ISI-JX)

Advanced Tumor | Metastatic Tumor

France
Novartis Pharmaceuticals

Terminated

A Phase I/Ib Study of NIZ985 in Combination With PDR001 in Adults With Metastatic Cancers

Metastatic and Advanced Solid Tumors

United States
M.D. Anderson Cancer Center

Recruiting

Combination Therapy for Cancer Related Fatigue in Patients With Metastatic Cancers

Fatigue | Metastatic Cancers

United States
Institut Claudius Regaud
Novartis

Terminated

Phase I Clinical and Pharmacokinetic Study of Pazopanib in a Population of Frail Elderly Patients According SIOG Criteria (VOTRAGE)

Metastatic Cancer (Different Solid Tumour Types)

France
Washington University School of Medicine
Varian Medical Systems

Completed

Simulation-Free Hippocampal-Avoidance Whole Brain Radiotherapy Using Diagnostic MRI-Based and Cone Beam Computed Tomography-Guided On-Table Adaptive Planning in a Novel Ring Gantry Radiotherapy Device

Intracranial Metastatic Disease From Any Solid Malignancy

United States
Hoffmann-La Roche

Completed

Study of Oral RXDX-101 in Adult Patients With Locally Advanced or Metastatic Cancer Targeting NTRK1, NTRK2, NTRK3, ROS1, or ALK Molecular Alterations. (STARTRK-1)

Locally Advanced Solid Tumors | Metastatic Solid Tumors

United States, Korea, Republic of
Eli Lilly and Company

Completed

A Study of LY2334737 in Participants With Cancer That is Advanced and/or Has Spread

Solid Tumor | Malignant Solid Tumor | Metastatic Tumor

Germany, United States, France
Vascular Biogenics Ltd. operating as VBL Therapeutics

Unknown

A Phase I Study to Assess the Safety and Distribution of VB-111 in Patients With Advanced Metastatic Cancer

Advanced and/or Metastatic Solid Organ Cancer

United States
M.D. Anderson Cancer Center

Not yet recruiting

A Randomized Phase II Basket Trial EXTENDing Efficacy of Systemic Therapy With Local Consolidative Therapy for OligoProgressive Metastatic Disease (EXTEND-OP)

OligoProgressive Metastatic Disease

United States
I-Mab Biopharma Co. Ltd.

No longer available

Expanded Access Protocol for Subjects With Relapsed or Refractory Advanced Solid Tumors Receiving TJ210001

Solid Tumor Metastatic Cancer Advanced Cancer
Centre Hospitalier Universitaire de Besancon

Completed

Evaluation of Immune Response Against Human Papillomavirus (HPV)in Patients With Metastatic Cancer of the Anal Canal (Epitopes-HPV01)

Metastatic Anal Canal Cancer | Human Papillomavirus

France
Memorial Sloan Kettering Cancer Center

Withdrawn

Detection of Acid Sphingomyelinase/Ceramide Pathway Activation in Radiotherapy Patients Using Intravoxel Incoherent Motion (IVIM) Diffusion-weighted Magnetic Resonance Imaging and Serum Biomarkers

Metastatic Disease to Bone | Metastatic Disease to Soft Tissue

United States
University Hospital, Linkoeping
Sahlgrenska University Hospital, Sweden; Medical Research Council of Southeast...

Recruiting

Evaluation of Tumour Growth and Oncological Treatment in Patients With CRLM Using Zebra Fish Embryo Model (CRLM-Z)

Colorectal Cancer Metastatic | Chemotherapy Effect | Tumour Metastasis | Tumor Growth

Sweden
Orion Biotechnology Polska Sp. z o.o.

Not yet recruiting

Study of OB-002 in Patients With Refractory Metastatic Cancer

Metastatic Colorectal Cancer | Metastatic Cancer | Metastatic Breast Cancer | Metastatic Urothelial Carcinoma | Metastatic Gastric Cancer | Metastatic Pancreatic Cancer
Fundación de Investigación Biomédica - Hospital...
Marcello Di Martino

Completed

Chemotherapy for Resectable Colorectal Liver Metastases

Metastatic Colorectal Cancer | Metastatic Liver Cancer

Spain, United Kingdom, France
Centre Hospitalier Universitaire de Nice

Completed

Circulating Tumor Cells and Neutrophils Count for Colorectal Metastatic Cancer

Metastatic Colorectal Cancer

France
Memorial Sloan Kettering Cancer Center

Completed

Use of a Video Decision Tool to Improve Informed Decision-Making in Hospitalized Patients Considering Palliative Radiation Therapy

Metastatic Cancer or Locally Advanced | Patients Receiving Palliative Radiation

United States
Suzhou Transcenta Therapeutics Co., Ltd.

Recruiting

A First-in-Human, Phase 1 Study of TST003 in Subjects With Solid Tumors

Colorectal Adenocarcinoma | Locally Advanced Solid Tumor | Metastatic Tumor

United States
Case Comprehensive Cancer Center

Recruiting

Spine Radiosurgery for Symptomatic Metastatic Neoplasms

Metastatic Neoplasm | Metastatic Neoplasm to the Spine

United States
Akeso

Not yet recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of AK114

Metastasis | Advanced or Metastatic Solid Tumors | Malignancy

Australia
Aadi Bioscience, Inc.

Recruiting

Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes (PRECISION 1)

Malignant Solid Neoplasm | Neoplasms | Cancer | Neoplasm Metastasis | Solid Tumor | Metastatic Cancer | Metastasis | Advanced Solid Tumor | Metastatic Solid Tumor | Advanced Cancer | Tumor | Malignant Neoplasm | Malignant Tumor | Tumors | Cancer Metastatic | Tumor, Solid | Malignant Solid Tumor | TSC | TSC1 | TSC2 | Metastatic Neoplasm

Korea, Republic of, United States, Puerto Rico
Takeda
Takeda Development Center Americas, Inc.

Recruiting

First-in-Human Study of TAK-280 in Participants With Unresectable Locally Advanced or Metastatic Cancer

Unresectable Locally Advanced or Metastatic Cancer

United States, Australia
Centre Leon Berard
Bayer

Active, not recruiting

A Retro-/Prospective, Non-interventional, Cohort Study in Adult Patients With Locally Advanced or Metastatic Tumors With a Neurotrophic Tyrosine Receptor Kinase (NTRK) Gene Fusion, Treated With Larotrectinib (LAROTRACKING)

Metastatic Cancer | Solid Tumor, Adult | Locally Advanced Solid Tumor

France
City of Hope Medical Center
National Cancer Institute (NCI)

Withdrawn

Perception of Cure Among Patients With Metastatic Cancer

Hematopoietic and Lymphoid Cell Neoplasm | Metastatic Malignant Solid Neoplasm

United States
Indiana University

Recruiting

Prospective Validation of a Points Score System Predicting 30-day Survival

Metastatic Cancer

United States
Rampart Health, L.L.C.

Recruiting

A Phase 2 Trial for Patients With Metastatic Solid Cancer

Metastatic Cancer

United States
Sanofi
BioNTech RNA Pharmaceuticals GmbH

Terminated

A First-in-Human Dose Escalation and Expansion Study to Evaluate Intratumoral Administration of SAR441000 as Monotherapy and in Combination With Cemiplimab in Patients With Advanced Solid Tumors

Metastatic Neoplasm

France, Spain, United States, Belgium, Germany, Netherlands
Cancer Research Antwerp

Completed

A Dose-escalation Trial of Stereotactic Ablative Body Radiotherapy for Non-spine Bone & Lymph Node Oligometastates (Destroy)

Metastatic Cancer

Belgium
Sanofi
Mirati Therapeutics Inc.; Revolution Medicines, Inc.

Active, not recruiting

Safety and Efficacy Study of SAR442720 in Combination With Other Agents in Advanced Malignancies

Metastatic Neoplasm

Taiwan, Chile, Korea, Republic of, United States, Argentina, Australia, Netherlands, Spain
SWOG Cancer Research Network
Proteus Digital Health, Inc.

Terminated

S1916 Digital Medicine Program for Pain Control in Cancer Patients

Metastatic Cancer

United States
Haining Health-Coming Biotech Co., Ltd.
Alphacait, LLC

Unknown

Clinical Studies by Using Alphacait to Screen Drugs for Advanced Solid Tumor

Metastatic Cancer

China
Bayer

Terminated

Refametinib (BAY86-9766) in Combination With Regorafenib (Stivarga, BAY73-4506) in Patients With Advanced or Metastatic Cancer

Neoplasms

United States

Clinical Trials on Metastatic

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