Clinical Trials on Metastatic Malignancies

Total 10820 results

German Cancer Research Center
University Hospital Freiburg; ABX CRO; Friedrich-Alexander-Universität Erlangen-Nürnberg

Completed

Ga-68-PSMA-11 in High-risk Prostate Cancer

Prostate Cancer | Prostate Cancer Metastatic | High-risk Prostate Cancer | Lymphnode Metastasis

Austria, Germany
Baptist Health South Florida

Withdrawn

Transplantation of Hematopoietic Stem Cells From HLA-compatible Donors in Patients With B-Cell Lymphoid Malignancies

Non-Hodgkin Lymphoma | Hematologic Malignancy | B-Cell Lymphoid Malignancies

United States
University Hospital Tuebingen
Ludwig-Maximilians - University of Munich; University Hospital Augsburg

Completed

Secondary Haplo HSCT for Relapse After Initial Allogeneic HSCT

Relapse of Hematological Malignancies
Regeneron Pharmaceuticals

Recruiting

Safety and Pharmacokinetics of Cemiplimab Anti-programmed Death-ligand 1 (Anti-PD-1) and Other Agents in Japanese Adult Patients With Advanced Malignancies

Advanced Malignancies

Japan
Zai Lab (Shanghai) Co., Ltd.

Completed

To Evaluate Pharmacokinetics of Tisotumab Vedotin in Chinese Subjects With Metastatic or Recurrent Solid Malignancies

Solid Malignancies

China
Shenzhen Geno-Immune Medical Institute

Unknown

Combination CAR-T Cell Therapy Targeting Hematological Malignancies

B-cell Malignancies

China
Nectin Therapeutics Ltd
Merck Sharp & Dohme LLC

Recruiting

A Study of NTX-1088, a Monoclonal Antibody Targeting the Poliovirus Receptor (PVR, CD155), as Monotherapy and Combined With Pembrolizumab

Cancer | Metastatic Cancer | Advanced Solid Tumor | Tumor, Solid | Locally Advanced Solid Tumor

United States, Israel
Akamis Bio
Bristol-Myers Squibb

Recruiting

Study of NG-641 in Combination With Nivolumab in Metastatic or Advanced Epithelial Tumours (NEBULA)

Metastatic Cancer | Epithelial Tumor

United States, United Kingdom
University Hospital, Ghent

Completed

The Inflammatory Response to Stress and Angiogenesis in Liver Resection

Colorectal Cancer | Metastatic Cancer | Liver Metastases | Liver Cancer
GERCOR - Multidisciplinary Oncology Cooperative...
Bristol-Myers Squibb

Active, not recruiting

iRECIST Evaluation's Relevance for DCR in MMR/MSI Metastatic Colorectal Cancer Patients on Nivolumab and Ipilimumab (NIPICOL)

Metastatic Cancer Colorectal

France
Sandy Srinivas

Terminated

Phase I Sodium Selenite in Combination With Docetaxel in Castration-resistant Prostate Cancer

Urologic Neoplasms | Prostate Cancer | Prostate Cancer Metastatic Disease

United States
Centre Francois Baclesse
Roche Pharma AG; Hospira, now a wholly owned subsidiary of Pfizer; Vifor Pharma

Terminated

Randomized Study Evaluating Agents Stimulants Erythropoiesis (ASE) Associated With Ferric Carboxymaltose (Ferinject ®) in Concomitant or Sequential Patients Treated for Cancer and With Anemia Associated With Functional Iron Deficiency

Solid Cancer Metastatic Disease | Lymphoid Disease

France
University of Manchester
Manchester University NHS Foundation Trust; The Christie NHS Foundation Trust; Perspect... and other collaborators

Unknown

Colorectal Liver Metastases: Novel Assessment Tools for Technical Resectability (CoNoR)

Cancer | Colorectal Cancer | Liver Metastasis Colon Cancer | Cancer Metastatic

United Kingdom
Eli Lilly and Company

Completed

A Study of LY3076226 in Participants With Advanced or Metastatic Cancer

Metastatic Cancer | Advanced Cancer

United States, Canada
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Combination Chemotherapy and Bevacizumab With the NovoTTF-100L(P) System in Treating Participants With Advanced, Recurrent, or Refractory Hepatic Metastatic Cancer

Metastatic Malignant Neoplasm in the Liver | Advanced Malignant Neoplasm | Refractory Malignant Neoplasm | Colorectal Carcinoma Metastatic in the Liver

United States
Case Comprehensive Cancer Center

Terminated

Weight-based Dosing for Dense Weekly Paclitaxel and Carboplatin in Overweight Patients w/ Body Surface Area (BSA) > 2.0

Gynecologic Malignancies

United States
Regeneron Pharmaceuticals
Sanofi

Completed

Study of REGN2810 (Anti-PD-1) in Patients With Advanced Malignancies

Advanced Cancer | Advanced Malignancies

United States, Spain, Australia
Amgen

Completed

Study to Develop a Screening Tool for Functional Capacity in Anemic Subjects With Nonmyeloid Malignancies Receiving Chemotherapy and Darbepoetin Alfa

Anemia | Non-Myeloid Malignancies
The Affiliated People's Hospital of Ningbo University
UTC Therapeutics Inc.

Recruiting

Study of CAR-T Cell Therapy in the Treatment of Relapsed/Refractory Hematological Malignancies

Lymphoma | Leukemia | Myeloma | Relapsed/Refractory Hematological Malignancies

China
Catherine Bollard
Johns Hopkins University; Children's National Research Institute

Recruiting

Multi-institutional Prospective Research of Expanded Multi-antigen Specifically Oriented Lymphocytes for the Treatment of VEry High Risk Hematopoietic Malignancies (RESOLVE)

Relapsed/Refractory Hematopoietic Malignancies, Acute Myeloid Leukemia and MDS

United States
Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co...

Completed

A Study of F0002-ADC in Chinese Patients With Refractory or Recurrent CD30+ Hematologic Malignancies.

Refractory or Recurrent CD30+ Hematologic Malignancies

China
M.D. Anderson Cancer Center

Recruiting

Radiologic Pathologic Correlation of Imaging to Distinguish True Progression From Pseudoprogression in Brain Malignancies

Brain Malignancies | Pseudoprogression

United States
University Hospital, Caen

Not yet recruiting

Cancer Therapy-related Cardiac Dysfunction Occuring in Children Treated by Anticancer Drugs for Malignancies

Cardiovascular Diseases | Children, Only | Malignancies
Incyte Corporation

Recruiting

Study of INCA32459 a LAG-3 and PD-1 Bispecific Antibody in Participants With Select Advanced Malignancies

Advanced Malignancies

Spain, United States, France, Belgium, Italy
AstraZeneca

Completed

An Open-Label, Multi-Centre, Study to Assess the Safety of Fixed-Dose Durvalumab + Tremelimumab Combination Therapy or Durvalumab Monotherapy in Advanced Solid Malignancies. (STRONG)

Advanced Solid Malignancies

United States, Germany, Italy, United Kingdom, Canada, France, Korea, Republic of, Netherlands
CJ Bioscience, Inc.

Recruiting

Safety, Tolerability, and Preliminary Efficacy of CJRB-101 With Pembrolizumab in Subjects With Selected Types of Advanced or Metastatic Cancer

Melanoma | NSCLC | Metastatic Cancer | Advanced Solid Tumor | Advanced Cancer | HNSCC

Korea, Republic of
Akamis Bio

Recruiting

First in Human Study With NG-641, a Tumour Selective Transgene Expressing Adenoviral Vector (STAR)

Metastatic Cancer | Epithelial Tumor

United States
University Health Network, Toronto

Recruiting

Femoral Bone Metastases

Cancer | Metastatic Malignant Neoplasm to Femur | Risk of Fracture

Canada
Akamis Bio

Completed

First in Human Study of NG-350A (an Oncolytic Adenoviral Vector Which Expresses an Anti-CD40 Antibody) (FORTITUDE)

Metastatic Cancer | Epithelial Tumor

United States
Wake Forest University Health Sciences

Completed

Study to Evaluate Safety, Tolerability, Maximum Tolerated Dose (MTD), Efficacy, and Pharmacokinetics (PKs) of CPI-613 Given Twice Weekly for Three Consecutive Weeks in Patients With Advanced Hematologic Malignancies

Advanced Hematologic Malignancies

United States
Jazz Pharmaceuticals

Completed

Lurbinectedin Monotherapy in Participants With Advanced or Metastatic Solid Tumors (EMERGE-201) (EMERGE-201)

Advanced Solid Tumor | Metastatic Solid Tumor | Urothelial Cancer | Poorly Differentiated Neuroendocrine Carcinomas | Homologous Recombination Deficient-Positive Malignancies Agnostic

United States
Novartis Pharmaceuticals

Completed

A Study to Determine the Absorption, Distribution, Metabolism, and Excretion of LBH589

Cancer Patients With Advanced Solid Tumors Including Lymphoma or Chronic Hematological Malignancies

United States
Ankara University

Recruiting

Metastatic Pathologic Fractures, Short Term Results

Metastatic Cancer | Bone Metastases | Pathologic Fracture

Turkey
University of Arkansas

Withdrawn

The P10s-PADRE Basket Trial: Vaccination of Metastatic Cancer Patients

Neoplasms by Site | Metastatic Cancer
University of Michigan Rogel Cancer Center

Completed

Genetic Risk of Osteonecrosis of the Jaw (ONJ) in Patients With Metastatic Cancer: Concordance Study

Breast Cancer

United States
UNC Lineberger Comprehensive Cancer Center

Completed

Safety, Efficacy, and Dosing of Stereotactic Radiosurgery for Hepato-cellular Carc/Colo-rectal Liver Metastases

Liver Neoplasms | Colonic Neoplasms | Metastatic Cancer to Liver

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

A Multifaceted Telemedicine-Based Intervention to Improve Outcomes of Cancer Patients Admitted to the ICU (EXPERT-IS)

Active Malignancies | Life Threatening Complication of the Malignancy or Its Treatments
BioMed Valley Discoveries, Inc

Completed

Safety Study of Intratumoral Injection of Clostridium Novyi-NT Spores to Treat Patients With Solid Tumors That Have Not Responded to Standard Therapies

Solid Tumor Malignancies

United States
St. Jude Children's Research Hospital
National Cancer Institute (NCI)

Completed

Melatonin Intervention For Neurocognitive Deficits in the St. Jude Lifetime Cohort

Cancer Malignancies

United States
Nantes University Hospital

Completed

Medico-economic Evaluation Comparing the Impact of the New Fixed-dose Nivolumab Regimen With the Old mg/kg Regimen in the Management of Patients With Metastatic Cancer (IMEPOCA)

Metastatic Cancer
Artios Pharma Ltd

Active, not recruiting

A Study of ART4215 for the Treatment of Advanced or Metastatic Solid Tumors

Breast Cancer | Metastatic Cancer | Advanced Cancer

United States, United Kingdom
Incyte Corporation

Completed

To Evaluate the Safety, and Pharmacokinetics of Parscaclisib in Participants With Normal Hepatic Function and Hepatic Impairment.

Advanced Malignancies

United States
Arcus Biosciences, Inc.
Gilead Sciences

Recruiting

A Safety and Efficacy Study of Treatment Combinations With and Without Chemotherapy in Adult Participants With Advanced Upper Gastrointestinal Tract Malignancies (EDGE-Gastric)

Gastrointestinal Tract Malignancies

United States, Korea, Republic of, France, Serbia, Canada
Abramson Cancer Center of the University of Pennsylvania

Completed

Assessing the Impact of Electronic Capture of Patient Reported Outcomes in Radiation Oncology

Patients With Lung, Breast, Head and Neck, or Pelvic Malignancies

United States
Boston Pharmaceuticals

Completed

Study of Paclitaxel in Combination With BOS172722 in Patients With Advanced Nonhaematologic Malignancies

Advanced Nonhaematologic Malignancies

United Kingdom
Lahey Clinic

Completed

Laparoscopic Narrow Band Imaging for Detection of Occult Cancer Metastases

Gastrointestinal and Gynecologic Malignancies

United States
Amgen

Completed

Treatment for Patients With Non-Myeloid Malignancies Receiving Chemotherapy

Cancer | Non-Myeloid Malignancies
4SC AG

Completed

Oral Histone Deacetylase Inhibitor 4SC-202 in Patients With Advanced Hematologic Malignancies (TOPAS)

Advanced Hematologic Malignancies

Germany
Canisius-Wilhelmina Hospital
ZonMw: The Netherlands Organisation for Health Research and Development

Recruiting

Dutch National Randomized Study: PSMA-PET/CT as a Triage Tool for Pelvic Lymph Node Dissection in Prostatectomy Patients (PSMA-SELECT)

Prostate Cancer | Prostate Cancer Metastatic | Lymph Node Metastases

Netherlands
National Cancer Institute (NCI)

Completed

Phase II Study of Metastatic Cancer That Overexpresses P53 Using Lymphodepleting Conditioning Followed by Infusion of Anti-P53 TCR-Gene Engineered Lymphocytes

Anti-p53 TCR-Gene

United States

Clinical Trials on Metastatic Malignancies

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