Clinical Trials on Metastatic Pancreatic Neuroendocrine Tumor

Total 5869 results

National Cancer Institute (NCI)

Recruiting

Evaluating the Addition of the Immunotherapy Drug Atezolizumab to Standard Chemotherapy Treatment for Advanced or Metastatic Neuroendocrine Carcinomas That Originate Outside the Lung

Advanced Extrapulmonary Neuroendocrine Carcinoma | Metastatic Extrapulmonary Neuroendocrine Carcinoma | Recurrent Extrapulmonary Neuroendocrine Carcinoma | Unresectable Extrapulmonary Neuroendocrine Carcinoma

United States
National Cancer Institute (NCI)

Completed

Temsirolimus and Bevacizumab in Treating Patients With Advanced Endometrial, Ovarian, Liver, Carcinoid, or Islet Cell Cancer

Uterine Carcinosarcoma | Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Uterine Corpus Carcinoma | Ovarian Endometrioid Adenocarcinoma | Ovarian Seromucinous Carcinoma | Endometrial Serous Adenocarcinoma | Lung Carcinoid Tumor | Metastatic... and other conditions

United States, Canada
University of California, San Francisco
University of California Pancreatic Cancer Consortium (UCPCC)

Recruiting

Genetic Predisposition Testing Program for Pancreatic Neuroendocrine Neoplasms (PanNEN)

Pancreatic Neuroendocrine Neoplasm

United States
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Recruiting

AMT-PET in Monitoring Telotristat Etiprate Treatment in Participants With MetastaticNeuroendocrine Neoplasm

Carcinoid Syndrome | Metastatic Nonfunctional Well Differentiated Neuroendocrine Neoplasm

United States
Orion Biotechnology Polska Sp. z o.o.

Not yet recruiting

Study of OB-002 in Patients With Refractory Metastatic Cancer

Metastatic Colorectal Cancer | Metastatic Cancer | Metastatic Breast Cancer | Metastatic Urothelial Carcinoma | Metastatic Gastric Cancer | Metastatic Pancreatic Cancer
University Hospital, Strasbourg, France

Recruiting

Multi-omics Characterization of Pancreatic Neuroendocrine Tumors and Carcinomas (Camune)

Cancer of Pancreas

France
Pfizer

Completed

The Safety And Efficacy Of Sunitinib In Chinese Patients With Progressive Advanced Or Metastatic Well-Differentiated Unresectable Pancreatic Neuroendocrine Tumors

Pancreatic Neuroendocrine Tumors

China
Grupo Espanol de Tumores Neuroendocrinos

Completed

Radiological Response of Pancreatic Neuroendocrine Tumors: Comparison Between the Choi and the RECIST Criteria (CRIPNET)

Pancreatic Neuroendocrine Tumors

Spain
Peking Union Medical College Hospital

Completed

Comparative Study of Robotic, Laparoscopic and Open Surgery for Enucleation of Benign Pancreatic Neoplasms

Pancreatic Neuroendocrine Tumors

China
Pfizer

Completed

Efficacy And Safety Of Sunitinib In Patients With Advanced Well-Differentiated Pancreatic Neuroendocrine Tumors

Pancreatic Neuroendocrine Tumors

Japan
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Completed

A Bioequivalence Study of Sunitinib Malate Capsules.

Renal Cell Carcinoma | Gastrointestinal Stromal Tumors | Pancreatic Neuroendocrine Tumor

China
Rutgers University

Unknown

Study Investigating MEN1 and SDHD in Familial Carcinoid Tumors

Carcinoid Neuroendocrine Cancer

United States
Novartis Pharmaceuticals

Active, not recruiting

LUTATHERA Injection General Use Result Survey

Somatostatin Receptor-positive Neuroendocrine Tumor

Japan
Genentech, Inc.

Active, not recruiting

Safety and Pharmacokinetics (PK) of Escalating Doses of Tiragolumab as a Single Agent and in Combination With Atezolizumab and/or Other Anti-Cancer Therapies in Locally Advanced or Metastatic Tumors

Advanced/Metastatic Tumors

Spain, United States, Korea, Republic of, Australia, France, Japan, Canada
Dermatologic Cooperative Oncology Group

Unknown

Standard Palliative Care Versus Standard Palliative Care Plus Polychemotherapy in Metastasized Malignant Melanoma

Metastatic Melanoma

Germany
Cylene Pharmaceuticals

Completed

Quarfloxin in Patients With Low to Intermediate Grade Neuroendocrine Carcinoma

Neuroendocrine Tumors | Carcinoid Tumor

United States
Novartis Pharmaceuticals

Completed

Phase IV Study of the Safety and Efficacy of Everolimus in Adult Patients With Progressive pNET in China

Pancreatic Neuroendocrine Tumors

China
Novartis Pharmaceuticals

Completed

Study of Safety and Efficacy of Alpelisib With Everolimus or Alpelisib With Everolimus and Exemestane in Advanced Breast Cancer Patients, Renal Cell Cancer and Pancreatic Tumors

Neoplasms | Kidney Neoplasms | Breast Neoplasms | Pancreatic Neuroendocine Neoplasms (pNETs)

France, Germany, United States, Netherlands, Italy, Spain, United Kingdom, Hong Kong, Hungary
Australasian Gastro-Intestinal Trials Group
Canadian Cancer Trials Group

Not yet recruiting

Cessation of Somatostatin Analogues After PRRT in Mid, Hind-Gut and Pancreatic Neuroendocrine Tumours (STOPNET)

Neuroendocrine Tumors

Australia
Merck Sharp & Dohme LLC

Recruiting

Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)

Von Hippel-Lindau Disease | Pancreatic Neuroendocrine Tumor | Pheochromocytoma/Paraganglioma | Advanced Gastrointestinal Stromal Tumor | HIF-2α Mutated Cancers

Canada, United States, Denmark, France, Germany, Hungary, Italy, Russian Federation, Spain, Sweden, Turkey, Israel, United Kingdom, Netherlands, Australia, China, Singapore, Japan
H. Lee Moffitt Cancer Center and Research Institute

Completed

Clinical Utility Assay as a Biomarker for Gastroenteropancreatic and Lung Neuroendocrine Tumors

Lung Neuroendocrine Neoplasm | Gastroenteropancreatic Neuroendocrine Tumor

United States
UNC Lineberger Comprehensive Cancer Center
Pfizer; BioMed Valley Discoveries, Inc

Recruiting

Ulixertinib/Palbociclib in Patients With Advanced Pancreatic and Other Solid Tumors

Melanoma | Pancreatic Cancer | Tumor, Solid

United States
University Hospital, Montpellier

Recruiting

Triple BRAFinh/MEKinh /antiPD1 Combined Therapy in Patients With BRAF Mutated Melanoma With Central Nervous System Metastasis

Metastatic Melanoma

France
Nantes University Hospital

Completed

TEP With 68-DOTANOC in Gastroenteropancreatic Neuroendocrine Tumors (68-DOTANOC-GEP)

Patients With Gastroenteropancreatic Neuroendocrine Tumors

France
National Cancer Institute (NCI)

Recruiting

Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells

Stage IV Prostate Cancer AJCC v8 | Metastatic Prostate Small Cell Neuroendocrine Carcinoma | Metastatic Prostate Adenocarcinoma With Neuroendocrine Differentiation | Metastatic Prostate Neuroendocrine Carcinoma

United States
Turning Point Therapeutics, Inc.

Terminated

A Study of Repotrectinib in Combination With Other Anticancer Therapies for the Treatment of Subjects With KRAS-Mutant Solid Tumors

Advanced Solid Tumor | Metastatic Solid Tumor | KRAS Mutation-Related Tumors

United States
CHU de Reims

Unknown

Interest of Whole-body MRI Correlated to Spreading Sequences for Staging Neuroendocrine Tumors (LAB-2013-01)

Neuroendocrine Tumors With Metastasis
M.D. Anderson Cancer Center

Active, not recruiting

Phase I, Open-Label, Study of Tumor Infiltrating Lymphocytes Engineered With Membrane Bound IL15 Plus Acetazolamide in Adult Patients With Metastatic Melanoma

Melanoma | Metastatic Melanoma | Tumor

United States
Ludwig-Maximilians - University of Munich

Unknown

Melanoma Inhibitory Activity (MIA): A Serological Marker for Metastatic Uveal Melanoma

Melanoma | Radiotherapy | Metastatic Disease

Germany
National Cancer Institute (NCI)

Completed

Bevacizumab and PEG-Interferon Alfa-2b in Treating Patients With Metastatic or Unresectable Carcinoid Tumors

Metastatic Gastrointestinal Carcinoid Tumor | Recurrent Gastrointestinal Carcinoid Tumor | Regional Gastrointestinal Carcinoid Tumor

United States
CHU de Reims

Completed

Diagnostic Performances of Urine and Plasma 5-hydroxyindolacetic Acid (5HIAA) Values in Patients With Small-intestine Neuroendocrine Tumors

Small-intestine Neuroendocrine Tumors (Carcinoid Tumors)

France
Mohammed M Milhem
Genentech, Inc.

Terminated

Treatment of a Resistant Disease Using Decitabine Combined With Vemurafenib Plus Cobimetinib (ML28604)

Melanoma | Metastatic Melanoma | BRAF-mutated Metastatic Melanoma | V600EBRAF-mutated Metastatic Melanoma

United States
CHU de Reims

Recruiting

Resection of the Primary Tumor vs no Resection in Asymptomatic Patients With Unresectable Synchronous Liver Metastases From siNEN (SI-NET)

Small Intestinal Neuroendocrine Tumor

France
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Irinotecan in Treating Patients With Advanced Neuroendocrine Tumors

Neuroendocrine Carcinoma | Carcinoma of Unknown Primary | Neuroendocrine Carcinoma of the Skin

United States
University Hospital, Montpellier

Not yet recruiting

Identification and Characterization of Circulating Tumor Cells Before and After Treatment (Surgery and Radiotherapy) in a Cohort of Patients Treated for Resectable Stage I-III Merkel Cell Carcinoma (MERCCALIBI)

Merkel Cell Carcinoma
Memorial Sloan Kettering Cancer Center

Recruiting

Pancrelipase in People With Pancreatic Ductal Adenocarcinoma (PDAC)

Pancreatic Cancer | Pancreatic Cancer Metastatic | Pancreatic Cancer Stage IV | Metastatic Pancreatic Carcinoma | Metastatic Pancreatic Adenocarcinoma | Pancreatic Carcinoma | Metastatic Pancreatic Cancer | Pancreatic Cancer Non-resectable | Metastatic Pancreatic Ductal Adenocarcinoma | Pancreatic Carcinoma... and other conditions

United States
National Cancer Institute (NCI)

Completed

Nivolumab (Anti-PD1), Tadalafil and Oral Vancomycin in People With Refractory Primary Hepatocellular Carcinoma or Liver Dominant Metastatic Cancer From Colorectal or Pancreatic Cancers

Metastatic Colorectal Cancer | Hepatocellular Carcinoma | Hepatocellular Cancer | Metastatic Pancreatic Cancer | Liver Metastasis

United States
European Organisation for Research and Treatment...

Terminated

Intravenous or Hepatic Arterial Infusion of Fotemustine in Treating Patients With Unresectable Liver Metastases From Eye Melanoma

Metastatic Cancer | Intraocular Melanoma

Switzerland, Italy, United Kingdom, Poland
Hoffmann-La Roche

Completed

Study of Oral RXDX-101 in Adult Patients With Locally Advanced or Metastatic Cancer Targeting NTRK1, NTRK2, NTRK3, ROS1, or ALK Molecular Alterations. (STARTRK-1)

Locally Advanced Solid Tumors | Metastatic Solid Tumors

United States, Korea, Republic of
Abramson Cancer Center at Penn Medicine
Roswell Park Cancer Institute; CARTI

Recruiting

CapTemY90 for Grade 2 NET Liver Metastases (CapTemY90)

Neuroendocrine Tumors | Neuroendocrine Tumor Grade 2

United States
Amgen

Completed

Open Label Extension Study of Conatumumab and Ganitumab (AMG 479)

Sarcoma | Lymphoma | Colorectal Cancer | Non-Small Cell Lung Cancer | Advanced Solid Tumors | Metastatic Cancer | Solid Tumors | Carcinoid | Locally Advanced

United States, Spain, Poland
Cambridge University Hospitals NHS Foundation Trust

Completed

Capecitabine and Streptozocin With or Without Cisplatin in Treating Patients With Unresectable or Metastatic Neuroendocrine Tumors

Islet Cell Tumor | Gastrointestinal Carcinoid Tumor

United Kingdom
University of Iowa
Molecular Insight Pharmaceuticals, Inc.

Withdrawn

90Y DOTA/Retinoic Acid for Neuroblastoma and Neuroendocrine Tumor (NET)

Neuroendocrine Tumor | Neuroblastoma

United States
University Hospital, Montpellier
Department of digestive surgery, Carémeau Hospital, 30900, Nîmes, France; Department... and other collaborators

Completed

Pancreatectomy for NET: External Evaluation of WHO 2017 Grading System (PanTEN)

Pancreatic Surgery

France
Frontier Medicines Corporation

Recruiting

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors (PROSPER)

Colorectal Cancer | Pancreatic Cancer | Non Small Cell Lung Cancer | Metastatic Solid Tumor | Solid Tumor, Adult | Unresectable Solid Tumor | KRAS G12C | Advanced Solid Tumors With KRAS G12C Mutations

United States
UNICANCER
GlaxoSmithKline; National Cancer Institute, France

Not yet recruiting

Dostarlimab for Locally Advanced or Metastatic Cancer (Non-colorectal/Non-endometrial) With Tumor dMMR/MSI (Pan-MSI-ACSE)

Soft Tissue Sarcoma | Pancreatic Adenocarcinoma | Gastric Adenocarcinoma | Neuroendocrine Carcinoma | Adrenocortical Carcinoma | Small Bowel Adenocarcinoma | Ampulla of Vater Carcinoma | Duodenum Adenocarcinoma

France
Melanoma and Skin Cancer Trials Limited

Recruiting

Targeted Therapy and Avelumab in Merkel Cell Carcinoma (GoTHAM)

Metastatic Merkel Cell Carcinoma

Australia
Incyte Corporation

Active, not recruiting

A Study of INCMGA00012 in Metastatic Merkel Cell Carcinoma (POD1UM-201)

Metastatic Merkel Cell Carcinoma

United Kingdom, United States, Germany, Canada, Czechia, Italy, France, Spain, Switzerland, Australia, Poland, Hungary
Merck KGaA, Darmstadt, Germany
Pfizer

Approved for marketing

Expanded Access to Avelumab for Treatment of Metastatic Merkel Cell Carcinoma (mMCC)

Metastatic Merkel Cell Carcinoma

France
Nicholas Fidelman, MD
Merck Sharp & Dohme LLC; BTG International Inc.

Active, not recruiting

Pembrolizumab With Liver-Directed or Peptide Receptor Radionuclide Therapy for Neuroendocrine Tumors and Liver Metastases

Neuroendocrine Neoplasm | Metastatic Malignant Neoplasm in the Liver

United States

Clinical Trials on Metastatic Pancreatic Neuroendocrine Tumor

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