Clinical Trials on Mild to Moderate Depression.

Total 707 results

Regeneron Pharmaceuticals
Sanofi

Completed

Efficacy and Safety of Dupilumab in Participants ≥12 to <18 Years of Age, With Moderate-to-severe Atopic Dermatitis

Hypersensitivity, Immediate | Dermatitis, Atopic | Moderate-to-Severe Atopic Dermatitis | Dermatitis, Dermatitis Atopic | Eczema, Skin Diseases, Skin | Diseases Genetic, Genetic | Diseases Inborn, Skin | Disease, Eczematous Skin | Hypersensitivity, Immune System Diseases

United States, Canada
Edwards Lifesciences
ICON plc

Terminated

Observational Registry on the HARPOON Device (REPLICATE)

Severe Degenerative Mitral Regurgitation Due to Mid-segment Posterior Leaflet Prolapse

Germany, Spain, Switzerland
nihat demir

Unknown

How Effect Olive Oil and Eoprotin on Immunological Parameters and Growth (RDS)

Premature Birth of Newborn | Breast Milk Expression
Novartis Pharmaceuticals

Active, not recruiting

2 Years Prospective Study to Collect Real-life Data on the Retention, Quality of Life, Effectiveness and Treatment Pattern of Secukinumab in Adult Patients With Moderate to Severe Plaque Psoriasis, Psoriatic Arthritis, Ankylosing Spondylitis and Non-radiographic Axial Spondyloarthritis (PROMPT)

Psoriatic Arthritis | Ankylosing Spondylitis | Moderate to Severe Plaque Psoriasis | Non-radiographic Axial Spondyloarthritis

Thailand
Kessler Foundation
University of California, San Diego; University of Michigan; Rehabilitation Hospital... and other collaborators

Recruiting

Comparison of Two Group Wellness Interventions for Individuals With Neurologic Conditions and Their Support Persons

Dementia | Traumatic Brain Injury | Alzheimer's Disease | Mild Traumatic Brain Injury | Brain Injury Traumatic Severe | Brain Injury Traumatic Moderate

United States
Ningbo No. 1 Hospital

Completed

Alcohol Consumption and Type 2 Diabetes Mellitus Risk in Nonalcoholic Fatty Liver Disease

Nonalcoholic Fatty Liver Disease | Type2 Diabetes Mellitus | Light-to-moderate Alcohol Consumption

China
Children's Memorial Health Institute, Poland
Siemens Healthcare Sp. z o.o.

Recruiting

Pediatric Patient Experience on a Diagnostic Path

Demyelinating Diseases | Urinary Incontinence | Brain Tumor | Headache | Visual Impairment | Growth Deficiency | Psychomotor Retardation, Mild to Severe

Poland
University College, London
Beijing Children's Hospital

Completed

Breastfeed a Better Youngster: the BABY Study (BABY)

Infant Behavior | Psychological Stress | Breastfeeding | Infant Development | Breast Milk Expression | Breastfeeding, Exclusive

China
Galena Biopharma, Inc.

Completed

Efficacy and Safety Study of NeuVax™ (Nelipepimut-S or E75) Vaccine to Prevent Breast Cancer Recurrence (PRESENT)

Breast Cancer With Low to Intermediate HER2 Expression

United States, United Kingdom, France, Israel, Germany, Canada, Russian Federation, Romania, Bulgaria, Czech Republic, Hungary, Poland, Ukraine
Assistance Publique Hopitaux De Marseille

Not yet recruiting

Effects on Biotrauma of NMBAs and PP Association During ARDS (CURA-PRONE)

Moderate to Severe Acute Respiratory Distress Syndrome

France
Galderma R&D

Completed

To Evaluate the Efficacy and Safety of Nemolizumab for 12 Weeks in Participants With Chronic Kidney Disease With Associated Moderate to Severe Pruritus (NemoCKDaP)

Chronic Kidney Disease Associated Moderate to Severe Pruritus

Spain, United States, Hungary, Poland
The Hospital for Sick Children

Completed

Heated Humidified High Flow Nasal Cannula Oxygen in Obstructive Sleep Apnea in Adolescents

Obesity | Central Sleep Apnea | Obstructive Sleep Apnea (Moderate to Severe)

Canada
Lawson Health Research Institute

Recruiting

Internet Delivered Cognitive Behavioural Therapy for Persons With Mild Traumatic Brain Injury

Depression | Anxiety | Mild Traumatic Brain Injury | Internet-Delivered Cognitive Behavioural Therapy

Canada
University of Illinois at Chicago

Completed

Evaluating the Impact of Focused Muscle Contraction Therapy in Retire APF Players (GH-APF)

Depression | Brain Injuries | Acute Pain | Chronic Pain Due to Injury

United States
Nordlandssykehuset HF
University Hospital of North Norway; UiT The Arctic University of Norway; Helsepartner... and other collaborators

Recruiting

A Naturalistic Trial of the Norwegian Sickness Absence Clinic. The NSAC Efficacy Study (NSAC)

Depression | Pain | Fatigue | Anxiety Disorders | Occupational Exposure | Musculoskeletal Disorder | Work Related Stress | Return to Work | Employment | Workplace Bullying | Sickness Absence

Norway
Impulse Dynamics

Recruiting

Assessment of CCM in HF With Higher Ejection Fraction (AIM HIGHer)

Heart Failure | Heart Failure With Preserved Ejection Fraction | Diastolic Heart Failure | Heart Failure With Mid Range Ejection Fraction | Heart Failure With Moderately Reduced Ejection Fraction

United States
Nordlandssykehuset HF
University Hospital of North Norway; UiT The Arctic University of Norway; Helgelandssykehuset... and other collaborators

Active, not recruiting

A Naturalistic Trial of Nudging Clinicians in the Norwegian Sickness Absence Clinic. The NSAC Nudge Study (NSAC)

Depression | Pain | Fatigue | Anxiety Disorders | Occupational Exposure | Musculoskeletal Disorder | Work Related Stress | Return to Work | Employment | Workplace Bullying | Sickness Absence

Norway
VA Office of Research and Development

Active, not recruiting

Neurobiological and Psychological Benefits of Exercise in Chronic Pain and PTSD (EXCPPTSD)

Chronic Musculoskeletal Pain | Posttraumatic Stress Disorder (PTSD) | Mild or Moderate Traumatic Brain Injury

United States
Peking University Cancer Hospital & Institute

Unknown

Performance of White Light, NBI and Iodine Staining Endoscopy in the Diagnosis of Esophageal Lesions

Esophageal Squamous Cell Carcinoma | Mild Dysplasia of Esophagus | Moderate Dysplasia of Esophagus | Severe Dysplasia of Esophagus | Carcinoma in Situ of Esophagus

China
Heidelberg Engineering GmbH

Completed

Repeatability of Static & Dynamic Composite Confocal Microscopy for Assessment of the Corneal Nerve Fiber Plexus in Early Diabetic Polyneuropathy

Normal Eyes of Subjects Without Diabetes Mellitus | Subjects With Diabetes Mellitus Type 2 Without Coexisting DPN | Subjects With Diabetes Mellitus Type 2 With Coexisting Early to Moderate DPN
Radboud University Medical Center
Merck Sharp & Dohme LLC

Completed

The Influence of GINkGo Biloba on the Pharmacokinetics of the UGT Substrate raltEgraviR (GINGER) (GINGER)

Depression | HIV Infections | Mild Cognitive Impairment

Netherlands
AIO-Studien-gGmbH
Novartis Pharmaceuticals; Assign Data Management and Biostatistics GmbH

Completed

Safety and Tolerability of Everolimus as Second-line Treatment in Poorly Differentiated Neuroendocrine Carcinoma / Neuroendocrine Carcinoma G3 (WHO 2010) and Neuroendocrine Tumor G3 - an Investigator Initiated Phase II Study (EVINEC)

Neuroendocrine Carcinoma, Grade 3 | Poorly Differentiated Malignant Neuroendocrine Carcinoma | Neuroendocrine Carcinoma, Grade 1 [Well-differentiated Neuroendocrine Carcinoma] That Switched to G3 | Neuroendocrine Carcinoma, Grade 2 [Moderately Differentiated Neuroendocrine Carcinoma]... and other conditions

Germany
University of Washington
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institute... and other collaborators

Completed

A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity Pilot (TSOS6)

Substance-Related Disorders | Depression | Alcohol-Related Disorders | Quality of Life | Suicidal Ideation | Mild Cognitive Impairment | Posttraumatic Stress Disorder
Massachusetts General Hospital
National Institutes of Health (NIH); National Institute on Aging (NIA)

Recruiting

Care Planning for a Loved One With Dementia: Knowledge, Preparing for Decisions, and Emotions

Dementia | Dementia Alzheimers | Caregiver Stress Syndrome | Caregiver Burnout | Dementia, Mild | Dementia Moderate | Dementia Severe | Dementia Frontotemporal

United States
Mansoura University

Completed

JAK2 Mutation May Predict Response and Guide First Line Treatment in Rheumatoid Arthritis

Response Assessment in Newly Diagnosed RA Patients at 3rd Month Was Evaluated by DAS28 and ACR in Relation to JAK Expression

Egypt
University of Oslo
Modum Bad

Completed

The Mental Health Status of the General Population During the COVID-19 Pandemic and Its Association With Adherence to Government-initiated Non-pharmacological Epidemiological Interventions (NPI's)

Depression | Generalized Anxiety | Adherence to Non-pharmacological Epidemiological Interventions (NPIs)

Norway
IGC Pharma LLC

Recruiting

IGC-AD1 Trial on Agitation in Dementia Due to Alzheimer's (IGC-AD1-P2)

Aggression | Depression | Anxiety | Alzheimer Disease | Memory Impairment | Agitated; State, Acute Reaction to Stress | Agitation,Psychomotor | Care Giving Burden | NPS | Aggressive Outburst

United States, Canada, Puerto Rico
Diakonhjemmet Hospital

Completed

Cognitive Behavioral Therapy for Insomnia (CBTi) in Patients With Mental Illness

Sleep Disorder | Insomnia | Sleep Initiation and Maintenance Disorders | Sleep Disturbance | Mental Illness | Depression, Anxiety | Insomnia Chronic | Psychological Disorder | Insomnia Due to Mental Disorder | Insomnia, Psychophysiological

Norway
University of Calgary
Hotchkiss Brain Institute, University of Calgary

Completed

rTMS Treatment of Persistent Headache and Post Concussion Symptoms Attributed to Mild Traumatic Injury to the Head (TOPiCS-rTMS)

Transcranial Magnetic Stimulation | Brain Injuries, Traumatic | Headache | Mild Traumatic Brain Injury | Post-Traumatic Headache | Concussion, Brain | Headaches Chronic

Canada
Wuhan University
Peking University; Pfizer

Unknown

Efficacy and Safety of Ziprasidone to Treat Depressive Symptoms in Patients With Schizophrenia

The Primary Evaluation is the Change From Baseline at End of Study for CDSS Total Scores. | The Secondary Efficacy Evaluations Include: MADRS, PANSS Total Scores and Subscales and Responder Rate; CGI-S and CGI-I Scales. | Safety Evaluations Include: Laboratory Test Abnormalities; BARS... and other conditions
Vastra Gotaland Region
Göteborg University

Terminated

Effects of Tofacitinib vs Methotrexate on Rheumatoid Arthritis Interstitial Lung Disease (PULMORA)

Rheumatoid Arthritis | ILD | Interstitial Lung Disease Due to Systemic Disease (Disorder) | RA

Sweden
VA Office of Research and Development

Completed

Multifamily Group to Reduce Marital Conflict and Disability in Veterans With mTBI (MFG-mTBI)

Depression | Posttraumatic Stress Disorders | Mild Traumatic Brain Injury

United States
Mesoblast International Sàrl

No longer available

Intermediate-size Expanded Access Program (EAP), Mesenchymal Stromal Cells (MSC) for Acute Respiratory Distress Syndrome (ARDS) Due to COVID-19 Infection

Moderate to Severe Acute Respiratory Distress Syndrome Associated With COVID-19

United States
University of Texas Southwestern Medical Center
Texas A&M University; University of Texas Rio Grande Valley

Completed

PST for Care Partners of Adults With Alzheimer's and Alzheimer'S-related Dementia

Mild Cognitive Impairment (MCI) | Alzheimer Disease | Lewy Body Dementia (LBD) | Frontotemporal Degeneration (FTD) | Vascular Contributions to Cognitive Impairment and Dementia (VCID) | Mixed Etiology Dementias (MED)

United States
Shanghai Bovax Biotechnology Co., Ltd.
Chongqing Bovax Biopharmaceutical Co., Ltd.

Completed

Evaluate the Safety and Primary Immunogenicity of 9-valent HPV Recombinant Vaccine in Chinese Healthy Females

Vulvar Cancer | Vaginal Cancer | CIN1 | CIN2 | VaIN1 | VaIN2 | VaIN3 | Genital Wart | AIS | Invasive Carcinoma | Cervical Cancers | CIN 3 | Vin III | Mild Dysplasia of Vulva | Moderate Dysplasia of Vulva

China
University Hospital Inselspital, Berne
University of Bern

Recruiting

Bern Birth Cohort / Trajectory of Microbiota Maturation in Healthy Bern Infants - a Network Approach (BeBiCo)

Microbial Colonization | Mental Health Disorder | Maturation of the Healthy Infant Intestinal Microbiota | Nutrition Disorder, Infant | Milk Expression, Breast

Switzerland
Norwegian School of Sport Sciences
National Dairy Council

Completed

The Health of Competitive Fitness Athletes

Depression | Exercise Addiction | Perfectionism | Binge Eating | Body Image | Eating Disorder | Resting Metabolic Rate | Dietary Deficiency | Bone Mineral Density, Low, Susceptibility to | Exercise-Related Amenorrhea | Dietary Amenorrhea

Norway
Centro Universitário de Anapolis

Recruiting

Post COVID-19 Pulmonary Rehabilitation Program (COVID19REHAB)

Lung Diseases | Covid19 | Muscle Weakness | Respiratory Insufficiency | COVID-19 Respiratory Infection | Anxiety Disorder; Mixed With Depression (Mild)

Brazil
Johns Hopkins University
Department of Defense Congressionally Directed Medical Research Program

Recruiting

CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms

Depression | Insomnia | Sleep | Traumatic Brain Injury | Memory Impairment | Head Injury | Cognitive Behavioral Therapy | Concussion, Brain | Post-traumatic Stress | Brain Injury Traumatic Mild

United States
City of Hope Medical Center

Recruiting

Early Detection of Advanced Adenomas and Colorectal Cancer (AACRC)

Colorectal Neoplasms | Colorectal Cancer | Colorectal Disorders | Colorectal Adenocarcinoma | Colorectal Cancer Stage II | Colorectal Cancer Stage III | Colorectal Cancer Stage IV | Colorectal Polyp | Colorectal Neoplasms Malignant | Colorectal Adenomatous Polyp | Colorectal Cancer Stage I | Colorectal Adenoma... and other conditions

United States, Italy, China, Spain, Japan
Shanghai Mental Health Center

Recruiting

The China Longitudinal Aging Study of Cognitive Impairment

Depression | Anxiety | Alzheimer Disease | Mild Cognitive Impairment | Dementia, Vascular | Dementia With Lewy Bodies | Dementia Frontal

China
University of Washington
National Institute on Alcohol Abuse and Alcoholism (NIAAA); National Institute... and other collaborators

Completed

A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and Comorbidity (TSOS6)

Substance-Related Disorders | Depression | Alcohol-Related Disorders | Quality of Life | Pain | Brain Injuries | Chronic Disease | Suicidal Ideation | Mild Cognitive Impairment | Posttraumatic Stress Disorder | Wounds and Injury

United States
University of North Carolina, Greensboro

Completed

Rhythmically Entrained Exercise in Community-Dwelling Older Adults (REECO)

Depression | Cognitive Impairment | Cognitive Dysfunction | Dementia | Alzheimer Disease | Exercise | Caregiver Burden | Healthy Aging | Fall | Mild Cognitive Impairment | Elderly | Executive Function | Gait | Mental Health | Cognitive Decline | Memory Disorders | Memory Impairment | Walking | Cognition | Physical Exertion | Music Therapy and other conditions

United States
Brigham and Women's Hospital

Recruiting

Targeting Human Milk Fortification to Improve Preterm Infant Growth and Brain Development

Preterm Birth | Neurodevelopmental Disorders | Breast Milk Expression | Nutrition Disorder, Infant | Brain Development Abnormality

United States
Novoic Limited
King's College London

Completed

Clinical Feasibility of Speech Phenotyping for Remote Assessment of Neurodegenerative and Psychiatric Disorders (RHAPSODY)

Parkinson Disease | Motor Neuron Disease | Amyotrophic Lateral Sclerosis | Alzheimer Disease | Bipolar Disorder | Mild Cognitive Impairment | Major Depressive Disorder | Frontotemporal Dementia | Primary Progressive Aphasia | Dementia, Vascular | Dementia With Lewy Bodies

United Kingdom
University of Southern California
National Institute on Aging (NIA); Huntington Hospital

Completed

Social Work Intervention Focused on Transitions (SWIFT)

Depression | Stroke | Hypertension | Diabetes | Cancer | Chronic Obstructive Pulmonary Disease | Asthma | Chronic Heart Failure | Heart Disease | Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention

United States
Harran University
Hasan Kalyoncu University

Not yet recruiting

The Effect of Probiotics Added to the Mother's Diet on Preterm Babies

Necrotizing Enterocolitis | Breast Milk Expression | Preterm | Late-Onset Neonatal Sepsis
Indiana University

Recruiting

Intervention to Change Affect Recognition and Empathy (ICARE)

Traumatic Brain Injury | Concussion, Severe | Concussion, Intermediate | Concussion With Brief Loss of Consciousness | Traumatic Brain Injury With Brief Loss of Consciousness | Traumatic Brain Injury With No Loss of Consciousness | Concussion With LOC 31 to 59 Minutes | Traumatic Brain Injury With... and other conditions

United States
University of California, Los Angeles
United States Department of Defense

Not yet recruiting

Personalized Brain Stimulation to Treat Chronic Concussive Symptoms

Depression | Anxiety | Dizziness | Headache | Post-Concussion Syndrome | Cognitive Symptom | Post-traumatic Stress Disorder | Dysautonomia | Mild Traumatic Brain Injury | Head Injury | Concussion, Brain | Irritability; Syndrome

United States
Aneurin Bevan University Health Board

Unknown

MORbidity PRevalence Estimate In StrokE (MORe PREcISE)

Depression | Stroke | Anxiety | Dysphagia | Cerebral Infarction | Mild Cognitive Impairment | Hemiplegia | Aphasia | Stroke, Ischemic | Stroke Hemorrhagic | Hemiparesis | CVA (Cerebrovascular Accident) | Dysarthria | Intracerebral Hemorrhage | Hemianopia | Hemispatial Neglect | CVA; Sequelae

United Kingdom

Clinical Trials on Mild to Moderate Depression.

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