Clinical Trials on Mitochondrial DNA Mutation in Switzerland

Total 318 results

University Hospital Inselspital, Berne

Completed

Nutritional Assessment in Mitochondrial Cytopathy (NAMITO)

Mitochondrial Diseases | Mitochondrial Myopathies | Mitochondrial Cytopathies

Switzerland
Mclean Hospital
Yale University; University of Lausanne

Not yet recruiting

MitoQ for Early-phase Schizophrenia-spectrum Disorder and Mitochondrial Dysfunction

Cognitive Impairment | Schizophrenia and Related Disorders | Mitochondrial Alteration

United States, Switzerland
Martin Berli
Bern University of Applied Sciences

Completed

Sensor Glove and Non-Invasive Vibrotactile Feedback Insole to Improve Hand Prostheses Functions and Embodiment (FeetBack)

Amputation; Traumatic, Hand

Switzerland
University of Zurich
ETH Zurich

Recruiting

CNS Changes Following Amputation

Amputation, Congenital | Upper Limb; Amelia

Switzerland
University Hospital, Basel, Switzerland

Completed

Clitoral Reconstruction (CR) in FGM/C Patients

Female Genital Mutilation / Cutting (FGM/C)

Switzerland
ETH Zurich

Recruiting

Enhancing Abilities in Amputees and Patients With Peripheral Neuropathy Through Restoration of Sensory Feedback

Lower Limb Amputation Below Knee (Injury) | Lower Limb Amputation Above Knee (Injury) | Diabetic Peripheral Neuropathy | Lower Limb Amputation Knee

Switzerland
iOMEDICO AG
Roche Pharma AG

Active, not recruiting

Registry for Molecular Testing, Treatment and Outcome of Patients With Solid Tumors Harboring a NTRK Gene Fusion (REALTRK)

NTRK Family Gene Mutation

Switzerland, Germany
University Hospital Inselspital, Berne
Swiss National Science Foundation

Recruiting

Metabolic Characterization of Space Occupying Lesions of the Brain (FASTMRSI)

Glioma | Brain Tumor | IDH Mutation

Switzerland
University Hospital, Geneva
Prof Laurent Kaiser; Dr Samuel Cordey; Dr Stavroula Masouridi-Levrat; Prof Christian... and other collaborators

Completed

DNA and RNA Viruses of the Blood Virome of Allogeneic Hematopoietic Stem Cell Transplant Recipients (GeBVir)

RNA Virus Infections | DNA Virus Infections | Hematopietic Stem Cell Transplantation | Blood Virome

Switzerland
Rehaklinik Bellikon
Cort X Sensorics GmbH

Unknown

Descriptive Study of Receptive Fields in Lower Limb Amputees

Lower Limb Amputation Below Knee (Injury)

Switzerland
Kantonsspital Aarau

Completed

Clinical Trial Comparing Conventional and Robot-assisted(Da Vinci®)Laparoscopic Interventions for Hysterectomy

Postoperative Complications | Intraoperative Complications | Laparoscopic Technique no Switch to Open | Duration of Surgery

Switzerland
University of Lausanne Hospitals

Recruiting

Clinical Trial Comparing Negative Pressure Wound Therapy and Standard Dry Dressings (BERLYTZ)

Amputation | Arthroplasty Complications | Prosthesis-Related Infections

Switzerland
Blueprint Medicines Corporation

Completed

(PROSPECTOR) Screening Study Evaluating the Prevalence of the KIT D816V Mutation in Patients With Systemic Mast Cell Activation

Systemic Mast Cell Activation | KIT D816V Mutation

United States, France, United Kingdom, Italy, Germany, Belgium, Spain, Switzerland
Pfizer

Completed

A Phase Ib/II Study of LGX818 in Combination With MEK162 in Adult Patients With BRAF Dependent Advanced Solid Tumors

Solid Tumors Harboring a BRAF V600 Mutation

United States, France, Italy, Singapore, Australia, Spain, Switzerland, Canada, Belgium
University Hospital, Basel, Switzerland

Recruiting

Leflunomide Treatment for MEN1 Patients - the LUMEN1 Trial (LUMEN1)

MEN1 Gene Mutation

Switzerland
Novartis Pharmaceuticals

Completed

Real-world Effectiveness of Asciminib and Treatment Patterns in Patients With Chronic Myeloid Leukemia With T315I Mutation - a Chart Review Study of Patients Treated in the Asciminib Managed Access Program (MAP)

Chronic Myeloid Leukemia With T315I Mutation

Switzerland
Swiss Tropical & Public Health Institute

Completed

Effects of Ward Cats in Patients With Substance Abuse, Depression and Psychosis at UPK Basel

Satisfaction | Station Atmosphere

Switzerland
ETOP IBCSG Partners Foundation
AstraZeneca

Active, not recruiting

Osimertinib and Locally Ablative Radiotherapy in Patients With Synchronous Oligo-metastatic EGFR Mutant NSCLC (STEREO) (STEREO)

NSCLC Stage IV | EGFR Gene Mutation

Singapore, Sweden, Korea, Republic of, Spain, Switzerland, Netherlands, Italy, Poland
University Hospital, Basel, Switzerland

Terminated

Telbivudine Versus Lamivudine for Maintenance Therapy of Patients With Chronic Hepatitis B and Negative HBV Viral Load After 6 Month of Treatment With Telbivudine (SASL28)

Hepatitis, Chronic

Switzerland
University of Zurich

Completed

Impact of Antioxidant Agents on the Number of DNA Double-strand Breaks After Radiation-based Cardiac Examinations

Focus of the Study: DNA Damage Due to Medical Diagnostic X-ray

Switzerland
Swiss Group for Clinical Cancer Research

Completed

Binimetinib in Addition to Standard Chemotherapy in KRAS Mutated NSCLC.

Lung Cancer | KRAS Gene Mutation | Advanced Non-small Cell Lung Cancer

Switzerland
Bavarian Nordic
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Dose-finding Study to Evaluate Immunogenicity of Three Different Dose Levels of the IMVAMUNE (MVA-BN) Smallpox Vaccine.

Smallpox

Switzerland
ETH Zurich
Neural Control of Movement laboratory ETH Zurich

Recruiting

multiSENSory Stimulation to tArgeT Sensory Loss and chronIc Pain in neurOpathic patieNts (SENSATION)

Diabetic Neuropathies | Amputation | Neuropathy | Neuropathy, Painful | Sensory Neuropathy

Switzerland
University Hospital, Geneva

Completed

A Comparison of Cotton and Flocked Swabs for Vaginal Self Collection

Human Papillomavirus Infection

Switzerland
University Hospital, Geneva

Completed

Knowledge and Attitudes Towards Human Papillomavirus Infections and HPV Vaccination

HPV-Related Cervical Carcinoma

Switzerland
University Children's Hospital Basel
Swiss National Science Foundation; Fondation Botnar

Completed

Measurement of Lipogenic Flux by Deuterium Resolved Mass Spectrometry Via Non-invasive Breath Analysis (D2OBREATH)

De Novo Lipogenesis (DNL)

Switzerland
Hoffmann-La Roche

Completed

An Observational Study of Valcyte (Valganciclovir) in D+/R- Liver Transplant Recipients

Cytomegalovirus Infections

Switzerland
University of Zurich
Division of Infectious Diseases and Hospital Epidemiology

Completed

Influence of Persistent CMV-infection on Immune Senescence

Immune Senescence

Switzerland
AstraZeneca
Merck Sharp & Dohme LLC; Myriad Genetic Laboratories, Inc.

Active, not recruiting

Assessment of the Efficacy and Safety of Olaparib Monotherapy Versus Physicians Choice Chemotherapy in the Treatment of Metastatic Breast Cancer Patients With Germline BRCA1/2 Mutations. (OlympiAD)

Breast Cancer Metastatic | BRCA 1 Gene Mutation | BRCA 2 Gene Mutation

Italy, Spain, United States, Czechia, Romania, France, Korea, Republic of, United Kingdom, Hungary, Japan, Peru, Poland, Russian Federation, Turkey, China, Taiwan, Bulgaria, Switzerland, Mexico
University Hospital, Basel, Switzerland

Recruiting

A Study to Assess Safety and Feasibility of Direct Infusions of Donor-derived Virus-specific T-cells in Recipients of Hematopoietic Stem Cell Transplantation With Post-transplant Viral Infections Using the Cytokine Capture System® (CCS)

Cytomegalovirus Infections | EBV | Adenovirus Infection | Cytokine Capture System | Allogenic Disease

Switzerland
University Hospital, Basel, Switzerland

Completed

Active Specific Intranodal Immunotherapy of Recombinant Vaccinia Virus in Locally Advanced to Metastatic Melanoma

Melanoma

Switzerland
University Hospital, Basel, Switzerland

Completed

Herpes Zoster: Risk Factors, Complications and Special Situations

Herpes Zoster

Switzerland
AstraZeneca

Completed

Efficacy, Safety, Tolerability of Gefitinib as 1st Line in Caucasian Patients With EGFR Mutation Positive Advanced NSCLC (IFUM)

Caucasian Patients With EGFR Mutation Positive Advanced NSCLC

Bulgaria, Italy, Poland, Spain, Turkey, United Kingdom, Romania, Norway, Hungary, Portugal, Greece, Switzerland, France
University Hospital Inselspital, Berne
Merck Sharp & Dohme LLC; Pfizer

Completed

Prevalence of Sexually Transmitted Infections (STIs) in HIV-infected Patients (CTNG)

HIV Infections | Herpes Simplex | Chlamydia Trachomatis | Neisseria Gonorrhoeae

Switzerland
University Hospital, Geneva

Recruiting

Immunity Against Varicella in Pediatric Orthotopic Liver Transplantation Recipients (VZVinOLTx)

Liver Disease | Varicella | Immunosuppression

Switzerland
University of Lausanne Hospitals

Completed

Cell-mediated Immunity for Prevention of CMV Disease

Cytomegalovirus Infections

Switzerland
Devirex AG

Terminated

A Study to Investigate the Efficacy, Safety and Tolerability of PEG in Patients With Genital Herpes

Genital Herpes

Switzerland
University of Zurich
Devirex AG

Completed

Place Controlled Study to Treat Recurrent Herpes Labialis.

Recurrent Herpes Labialis

Switzerland
Prof Patrice Lalive

Recruiting

Immunogenicity of the Recombinant Zoster Vaccine in Multiple Sclerosis Patients (MSHINGVAX)

Zoster | Shingles

Switzerland
University Hospital, Basel, Switzerland

Recruiting

Occurrence of Antibodies Cross-reacting With Autoantigens in Primary EBV Infection

Epstein-Barr Virus (EBV) Infection

Switzerland
GlaxoSmithKline

Completed

Safety and Immunogenicity of 3 Lots of GSK Biologicals' HBV-MPL Vaccine and Engerix™-B in Healthy Volunteers ≥ 15y

Hepatitis B

Australia, Czech Republic, Germany, Italy, Netherlands, Switzerland, United Kingdom
Kantonsspital Aarau
ETH Zurich

Completed

Blink Restoration in Patients With Facial Nerve Palsy (NEURO-BLINK)

Facial Nerve Palsy

Switzerland
A. Vogel AG
University Children's Hospital, Zurich

Withdrawn

Echinaforce Junior Bioavailability Trial

Common Cold

Switzerland
University of Bern

Completed

ROCO - Self-help for People With Psychological Distress Due to the Covid-19 Situation (ROCO)

Psychological Distress | Coronavirus | Adjustment, Psychological

Switzerland
University Hospital, Basel, Switzerland
University of Basel; Swiss Federal Institute of Technology; University Children...

Completed

Prospective Analysis of Seasonal Influenza - Viral Transmission and Evolution in the City of Basel, Switzerland

Influenza

Switzerland
Crucell Holland BV

Completed

Re-licensing Study to Assess Inflexal V Formulated With WHO Recommended Influenza Strains (2013-14)

Influenza

Switzerland
Novartis Vaccines

Completed

Study to Evaluate Safety, Tolerability and Immunogenicity of a Bedside Mixing Combination of Two Adjuvanted Influenza Vaccines

Influenza

Switzerland
Crucell Holland BV

Completed

Re-licensing Study to Assess Inflexal V Formulated With WHO Recommended Influenza Strains

Influenza

Switzerland
Crucell Holland BV

Completed

A Re-licensing Study to Assess the Efficacy of Inflexal V Formulated With WHO Recommended 2008/2009 Influenza Virus Strains for the Northern Hemisphere

Influenza

Switzerland
Crucell Holland BV

Completed

A Re-licensing Study to Assess the Efficacy of Inflexal V Formulated With WHO Recommended 2010/2011 Influenza Virus Strains for the Northern Hemisphere

Influenza

Switzerland

Clinical Trials on Mitochondrial DNA Mutation in Switzerland

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