Clinical Trials on Mitral Regurgitation

Total 19175 results

Innovalve Bio Medical Ltd.

Recruiting

TVMR With the Innovalve System Trial - Pilot in Georgia (TWIST-PILOT-GE)

Mitral Valve Regurgitation (Degenerative or Functional)

Georgia
Innovalve Bio Medical Ltd.

Not yet recruiting

TVMR With the Innovalve System Trial - TWIST-BE TWIST-PILOT-BE

Mitral Valve Regurgitation (Degenerative or Functional)
Innovalve Bio Medical Ltd.

Recruiting

TVMR With the Innovalve System Trial - Pilot Study in Italy (TWIST-PILOT-IT)

Mitral Valve Regurgitation (Degenerative or Functional)

Italy
Innovalve Bio Medical Ltd.

Recruiting

TVMR With the Innovalve System Trial - Early Feasibility Study (TWIST-EFS)

Mitral Valve Regurgitation (Degenerative or Functional)

United States
University Hospital Birmingham NHS Foundation Trust
British Heart Foundation

Completed

The Role of Myocardial Fibrosis in Degenerative Mitral Regurgitation

Mitral Regurgitation | Mitral Valve Regurgitation

United Kingdom
Edwards Lifesciences

Terminated

Edwards Cardioband System ACTIVE Pivotal Clinical Trial (ACTIVE) (ACTIVE)

Mitral Regurgitation | Mitral Insufficiency | Functional Mitral Regurgitation

United States
Sun Yat-sen University
First Affiliated Hospital, Sun Yat-Sen University; Third Affiliated Hospital... and other collaborators

Recruiting

Dapagliflozin Effect on FunctiOnal Mitral Regurgitation and Myocardial Fibrosis (DEFORM) (DEFORM)

Functional Mitral Regurgitation

China
Insel Gruppe AG, University Hospital Bern
University Hospital, Basel, Switzerland; Cardiocentro Ticino; Triemli Hospital

Recruiting

Prediction of Reverse Remodeling and Outcome in Patients With Severe Secondary Mitral Valve Regurgitation Undergoing Transcatheter Edge-to-edge Mitral Valve Repair (PRE-MITRA)

Severe Mitral Regurgitation

Switzerland
National Heart, Lung, and Blood Institute (NHLBI)

Active, not recruiting

NHLBI DIR Transcatheter Mitral Cerclage Annuloplasty Early Feasibility Study

Functional Mitral Regurgitation

United States
4C Medical Technologies, Inc.

Recruiting

AltaValve Early Feasibility Study Protocol

Mitral Regurgitation | Mitral Valve Regurgitation | Mitral Valve Incompetence | Mitral Insufficiency | Mitral Incompetence

United States
Oxford University Hospitals NHS Trust
Edwards Lifesciences

Recruiting

Early Discharge After Mitral and Tricuspid Edge-to-edge Repair: an Assessment of Feasibility and Safety (EARLY-Edge)

Heart Failure | Mitral Regurgitation | Tricuspid Regurgitation | Mitral Repair

United Kingdom
Ancora Heart, Inc.

Completed

Feasibility of the AccuCinch® System for Left Ventricular Reshaping of the Mitral Apparatus to Reduce Functional Mitral Regurgitation and Improve Left Ventricular Function (LVRECOVER)

Severe Functional Mitral Regurgitation and Heart Failure

Australia
Tau Pnu Medical Co., Ltd.

Completed

Atrial Functional Mitral Regurgitation Response In Mitral Loop Cerclage Annuloplasty (AFRICA Study) (AFRICA)

Heart Failure | Atrial Functional Mitral Regurgitation

Korea, Republic of
Centre Cardiologique du Nord
Campus Bio-Medico University; University of Genova; Henri Mondor University Hospital and other collaborators

Enrolling by invitation

Transcatheter Versus Standard Surgical Mitral Valve Operation for Secondary Mitral Regurgitation (TEERMISO)

Severe Mitral Valve Regurgitation (Disorder)

France
Saint Petersburg State University, Russia

Suspended

Stress Echo for Ischemic Mitral Valve Surgery (SURVIVE)

Ischemic Mitral Regurgitation

Russian Federation
Montreal Heart Institute
Abbott Medical Devices

Unknown

MitraClip for the Treatment of Moderate Functional Mitral Regurgitation: EVOLVE-MR (EVOLVE-MR)

Heart Failure | Mitral Regurgitation | Mitral Valve Regurgitation Due to Cardiomyopathy (Disorder)

Canada
University Cardiology

Unknown

Effect of Ranolazine on Valvular Disease in Patients With Pacemakers (REIN-MR)

Ischemic Mitral Regurgitation

United States
Laval University
Canadian Institutes of Health Research (CIHR)

Recruiting

Serotonin Receptor Blockers in Ischemic Mitral Regurgitation (CYPRO-MR)

Ischemic Mitral Regurgitation

Canada
Nanjing Medical University
The First Affiliated Hospital of Anhui Medical University; Nanjing First Hospital... and other collaborators

Not yet recruiting

Concomitant Tricuspid Repair in Patients With Left Heart Surgery

Mitral Regurgitation | Cardiopulmonary Bypass | Tricuspid Regurgitation

China
Edwards Lifesciences

Active, not recruiting

Edwards EVOQUE Eos MISCEND Study

Mitral Valve Regurgitation (Degenerative or Functional)

United States, Canada
Shaare Zedek Medical Center

Completed

Surgical Correction of Moderate Ischemic Mitral Regurgitation

Moderate Ischemic Mitral Regurgitation

Israel
Cardiac Dimensions, Inc.

Recruiting

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR

Heart Diseases | Cardiovascular Diseases | Heart Failure | Heart Valve Diseases | Mitral Valve Insufficiency | Functional Mitral Regurgitation

United States, France, Greece, Poland
Konkuk University Medical Center

Completed

Acute Normovolemic Hemodilution on ROTEM in Cardiac Surgery

Mitral Regurgitation | Tricuspid Regurgitation | Mitral Stenosis

Korea, Republic of
Konkuk University Medical Center

Completed

Acute Normovolemic Hemodilution on Serum-creatinine Concentration in Cardiac Surgery

Mitral Regurgitation | Tricuspid Regurgitation | Mitral Stenosis

Korea, Republic of
Atlantic Health System

Recruiting

Comparison Study of Echocardiography and Cardiovascular Magnetic Resonance Imaging in the Assessment of Mitral and Aortic Regurgitation

Mitral Regurgitation | Aortic Regurgitation

United States
Ospedale San Raffaele

Unknown

Expiratory Flow Limitation and Mechanical Ventilation During Cardiopulmonary Bypass in Cardiac Surgery

Mitral Regurgitation | Aortic Regurgitation

Italy
Michele De Bonis

Completed

LOng-Term Fate of Moderate Aortic Regurgitation Left Untreated at the Time of Mitral Valve Surgery

Mitral Regurgitation | Aortic Regurgitation

Italy
University of Luebeck

Not yet recruiting

Treatment of Functional Mitral Regurgitation in Patients With Atrial Fibrillation (CAMERA-Pilot)

Atrial Fibrillation | Mitral Regurgitation Functional
Deutsches Herzzentrum Muenchen

Recruiting

The Prospecive OBSERVational Munich Interventional MITRAl-Valve Registry (OBSERV-MITRA)

Mitral Valve Stenosis | Mitral Valve Regurgitation | Tricuspid Valve Regurgitation

Germany
Centre Hospitalier Universitaire, Amiens

Recruiting

Early Mitral ValvE Repair Versus Watchful Waiting for Asymptomatic SEvere Degenerative Mitral Regurgitation (REVERSE-MR)

Degenerative Mitral Regurgitation (MR) Due to Leaflet Prolapse

France
Abbott Medical Devices

Completed

ACCESS-Europe A Two-Phase Observational Study of the MitraClip® System in Europe (ACCESS-EU)

Mitral Valve (MV) Regurgitation

Germany
University Hospital, Clermont-Ferrand

Completed

Use of Pre-operative Global Longitudinal Strain to Predict Post-operative Left Ventricular Dysfunction in Mitral Regurgitation Surgery (DysPO IM)

Severe Mitral Regurgitation | Preserved Ventricular Ejection Fraction

France
Ziekenhuis Oost-Limburg
Jessa Hospital

Recruiting

Sacubitril-Valsartan in Heart Failure With Preserved Ejection Fraction and Secondary Mitral Valve Regurgitation (PRAISE-MR)

Heart Failure With Preserved Ejection Fraction | Functional Mitral Regurgitation

Belgium
Mayo Clinic

Recruiting

Watchman for Patients With Atrial Fibrillation Undergoing Transcatheter Mitral Valve Repair (WATCH-TMVR) (WATCH-TMVR)

Nonvalvular Atrial Fibrillation | Severe Degenerative Mitral Regurgitation

United States, Canada
Edwards Lifesciences
ICON plc

Terminated

Observational Registry on the HARPOON Device (REPLICATE)

Severe Degenerative Mitral Regurgitation Due to Mid-segment Posterior Leaflet Prolapse

Germany, Spain, Switzerland
Fundación para la Investigación Biosanitaria del...
Meditrial Europe Ltd.

Not yet recruiting

Early Transcatheter Mitral Valve Repair After Myocardial Infarction (EMCAMI)

Acute Mitral Regurgitation

Spain, Italy, Netherlands, Israel
Universitätsklinikum Hamburg-Eppendorf
University Hospital, Bordeaux; Montreal Heart Institute

Recruiting

CHoice of OptImal transCatheter trEatment for Mitral Insufficiency Registry (CHOICE-MI)

Mitral Regurgitation

Switzerland, United States, Denmark, United Kingdom, France, Canada, Germany, Australia, Italy, Norway
Edwards Lifesciences

Active, not recruiting

SAPIEN M3 EFS: Early Feasibility Study of the Edwards SAPIEN M3 System for the Treatment of Mitral Regurgitation (SAPIEN M3 EFS)

Mitral Regurgitation | Mitral Disease

United States, Canada
Medtentia International Ltd Oy

Completed

5-Year Follow-Up Safety and Performance Evaluation of the Medtentia Annuloplasty Ring in Adults

Mitral Regurgitation | Mitral Insufficiency

Finland
Istanbul University - Cerrahpasa (IUC)

Enrolling by invitation

Biomechanical Taping on Low Back Pain With Increased Foot Pronation

Low Back Pain | Functional Mitral Regurgitation | Taping | Foot Posture

Turkey
Edwards Lifesciences

Recruiting

MiCLASP Post Market Clinical Follow-Up (PMCF) Study (MiCLASP)

Mitral Regurgitation | Mitral Insufficiency

Switzerland, Germany, Austria, Greece, Italy, Netherlands, Poland, Spain, United Kingdom
Medtentia International Ltd Oy

Terminated

Study on Safety and Performance of Medtentia Mitral Valve Repair System in Surgical Repair of Mitral Regurgitation

Mitral Regurgitation | Mitral Insufficiency

Finland
Instituto Dante Pazzanese de Cardiologia
Edwards Lifesciences

Recruiting

Randomized Trial of Transcatheter Valve-in-Valve vs Redo Surgery for Bioprosthetic Mitral Dysfunction

Mitral Prosthetic Valve Stenosis and Regurgitation

Brazil
IRCCS San Raffaele

Unknown

Percutaneous Mitral Valve Repair in Cardiogenic Shock: Mitra-Shock Study (MSS)

Mitral Regurgitation Functional

Italy
Polares Medical SA
Polares Medical, Inc.

Not yet recruiting

EXPLORE MRace: Early Feasibility Experience of Posterior Leaflet Restoration to Reduce Mitral Regurgitation Using the MRace Implant (EXPLORE MRace)

Mitral Valve Disease

Brazil
P+F Products + Features GmbH
Meditrial USA Inc.

Not yet recruiting

Munich Transcatheter Mitral Valve Safety and Effectiveness (MUSE)

Mitral Regurgitation | Mitral Valve Disease

Brazil, Argentina, Chile
Polares Medical SA

Terminated

Early Feasibility EXperience of Posterior Leaflet RestOration to REduce Mitral Regurgitation (EXPLORE MR)

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Disease

Switzerland, Germany
Cardiovalve Ltd.
Meditrial Europe Ltd.; Meditrial SrL

Recruiting

AHEAD: European Feasibility Study of the Cardiovalve Transfemoral Mitral Valve System (AHEAD)

Mitral Regurgitation | Mitral Valve Disease

Germany, Italy, Greece
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Evaluation of Mitral Valve Insufficiency Under General Anesthesia (MITIGATE)

Mitral Regurgitation | Mitral Valve Insufficiency | Mitral Valve Disease

Netherlands
Michele De Bonis

Completed

Durability at 20 Years of Quadrangular Resection With Annular Plication for Mitral Regurgitation

Mitral Valve Disease

Italy

Clinical Trials on Mitral Regurgitation

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