Clinical Trials on Mitral Valve Regurgitation

Total 21002 results

Kathirvel Subramaniam
Pacira Pharmaceuticals, Inc

Completed

Comparison of Sternal Wound Infiltration With Liposomal Bupivacaine v. Bupivacaine Hydrochloride

Coronary Artery Disease | Valve Regurgitation, Tricuspid | Coronary Artery Stenoses | Valve Regurgitation, Mitral

United States
IRCCS San Raffaele

Unknown

Percutaneous Mitral Valve Repair in Cardiogenic Shock: Mitra-Shock Study (MSS)

Mitral Regurgitation Functional

Italy
Ospedale San Raffaele
Istituto Clinico Humanitas; Central Clinical Hospital of the Ministry of Internal...

Recruiting

Annuloplasty for Not-Severe TR in Patients Undergoing MV Repair Versus Mitral Repair Only (NOSTRUM) (NOSTRUM)

Mitral Regurgitation | Tricuspid Disease

Italy, Poland
Scientific Institute San Raffaele

Unknown

Transcatheter Mitral Valve Repair as Bridge Therapy to Heart Transplantation (MitraBridge)

Heart Failure | Mitral Regurgitation | End-stage Heart Failure

Italy
University of Alabama at Birmingham
National Heart, Lung, and Blood Institute (NHLBI); AstraZeneca

Completed

Molecular Mechanisms of Volume Overload-Aim 1(SCCOR in Cardiac Dysfunction and Disease) (P1A1)

Mitral Regurgitation

United States
Medical University of Vienna

Not yet recruiting

Edge-to-edge Mitral Valve Repair in ATTR-CM (MILLENNIAL)

Mitral Regurgitation | ATTR-Cardiomyopathy | Edge-to-Edge Mitral Valve Repair
Hospices Civils de Lyon

Recruiting

Impact of Preoperative Myocardial Fibrosis Related to Mitral Valve Prolapse on Postoperative Left Ventricular Remodeling (IMPARED)

Regurgitation, Mitral

France
Abbott Medical Devices

Active, not recruiting

Feasibility Study of the Tendyne Mitral Valve System in Mitral Annular Calcification

Cardiovascular Diseases | Heart Valve Diseases | Mitral Regurgitation | Mitral Insufficiency | Valve Heart Disease | Mitral Annulus Calcification | Mitral Valve Disease | Mitral Annular Calcification | Heart Valve Calcification

United States
Mayra Guerrero

Recruiting

The MITRAL II Pivotal Trial (Mitral Implantation of TRAnscatheter vaLves). (MITRAL-II)

Mitral Regurgitation | Mitral Valve Disease | Mitral Annular Calcification | Mitral Stenosis

United States
Groupe Hospitalier Paris Saint Joseph

Completed

Exercise-induced in Secondary Mitral Regurgitation: Analysis of Echocardiographic Parameters at Rest Predicting the Onset of Significant Exercise-induced Mitral Regurgitation (IM EFFORT)

Cardiac Disease

France
Assiut University

Not yet recruiting

Left Chamber Function in Mitral Regurgitation and Predicting Outcome After Replacement and Targeting for Early Surgery

Mitral Regurgitation
Metanoic Health Ltd.
Abbott Medical Devices

Completed

Incidence of Significant Mitral Regurgitation in Acute Heart Failure Patients (MRAHF)

Mitral Regurgitation | Acute Heart Failure

United Kingdom
China National Center for Cardiovascular Diseases
Shanghai Children's Medical Center; Chinese Academy of Medical Sciences, Fuwai... and other collaborators

Recruiting

Study of Innovative Drug Treatment Therapy for Pediatric Mitral Regurgitation

Congenital Mitral Insufficiency

China
Imperial College London
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Unknown

Online Videodensitometric Assessment of Aortic Regurgitation in the Cath-Lab (OVAL)

Heart Valve Diseases | Aortic Valve Insufficiency | Paravalvular Aortic Regurgitation | Regurgitation, Aortic

Netherlands
Imperial College London
British Heart Foundation; Humboldt-Universität zu Berlin

Completed

Identifying an Ideal Cardiopulmonary Exercise Test Parameter (PVA)

Mitral Regurgitation | Left Ventricular Systolic Dysfunction

United Kingdom
Rabin Medical Center
Mayo Clinic; IRCCS San Raffaele; Medical University of Vienna; University of British... and other collaborators

Unknown

Transcatheter Treatment for Combined Aortic and Mitral Valve Disease. The Aortic+Mitral TRAnsCatheter (AMTRAC) Valve Registry (AMTRAC)

Aortic Stenosis | Mitral Regurgitation

Israel
Hospices Civils de Lyon

Withdrawn

Effectiveness and Safety of Mitral Valve Repair With the NeoChord DS1000 Artificial Chordae Delivery System Versus Conventional Surgery in Patients With Severe Primary Mitral Regurgitation Due to Isolated Leaflet Prolapse (MITRACHORD)

Cardiovascular Diseases

France
Azienda Ospedaliero, Universitaria Pisana

Not yet recruiting

Patients With Severe TrIcuspid Regurgitation After triCvALve System Implantation (CRITICAL)

Severe Tricuspid Valve Regurgitation
Xiamen Cardiovascular Hospital, Xiamen University

Recruiting

The China Mviv Registry

Heart Failure | Mitral Regurgitation | Mitral Stenosis | Mitral Stenosis With Insufficiency | Bioprosthesis Failure

China
Technische Universität Dresden
Zentrum für Klinische Studien Leipzig; University Medical Center Mainz; KKS Dresden

Recruiting

Treatment of Concomitant Mitral Regurgitation by Mitral Valve Clipping in Patients With Successful Transcatheter Aortic Valve Implantation. (MITAVI)

Aortic Stenosis | Mitral Regurgitation

Germany
Meshalkin Research Institute of Pathology of Circulation

Completed

Flexible Band vs Rigid Ring for Degenerative Mitral Valve Disease

Mitral Regurgitation
Shaare Zedek Medical Center

Completed

Repair of Ischemic Mitral Regurgitation: Comparison Between Flexible and Rigid Annuloplasty Rings (IMR2)

Mitral Regurgitation

Israel
Na Homolce Hospital
Centre of Cardiovascular and Transplantation Surgery, Czech Republic; St. Anne... and other collaborators

Recruiting

Early Aortic vaLve surgEry Versus wAtchful waitiNg Strategy in Severe Asymptomatic aOrtic reguRgitation (ELEANOR)

Aortic Valve Regurgitation

Serbia, Czechia, Belgium
Edwards Lifesciences

Active, not recruiting

Magna® Mitral Pericardial Bioprostheses Post-Approval Study Protocol

Coronary Artery Disease | Heart Failure | Mitral Valve Regurgitation | Mitral Valve Incompetence

Canada, United States, Austria, Germany
Assiut University

Not yet recruiting

Surgical Strategies in Moderate Ischemic Mitral Insufficiency in Patients Undergoing Coronary Artery Bypass Graft

Moderate Ischemic Mitral Regurgitation

Egypt
Ospedale San Raffaele

Completed

Minimally Invasive or Conventional Edge-To-Edge Repair for Severe Mitral Regurgitation Due to Bileaflet Prolapse in Barlow's Disease: Does the Surgical Approach Have an Impact on the Long-term Results?

Barlow's Disease | Prolapse; Mitral
St. Antonius Hospital
ZonMw: The Netherlands Organisation for Health Research and Development

Enrolling by invitation

Evaluating Edge-to-edge Transcatheter Tricuspid Valve Repair in Patients With Severe Symptomatic Tricuspid Regurgitation (TRACE-NL)

Cardiac Catheterization | Tricuspid Valve Regurgitation, Nonrheumatic | Heart Failure, Right Sided | Valve Regurgitation, Tricuspid

Netherlands
4Tech Cardio Ltd.

Completed

Percutaneous Treatment of Tricuspid Valve Regurgitation With the TriCinch System™ (PREVENT)

Tricuspid Regurgitation

Germany, France, Italy, Netherlands
Michele De Bonis

Completed

Surgical Treatment of Tricuspid Valve Regurgitation in Patients With Cardiac Implantable Electronic Devices: Long Term Results

Tricuspid Regurgitation

Italy
Assiut University

Not yet recruiting

Effect of Significant Ischemic Mitral Regurgitation on the Outcome of ST Segment Elevation Myocardial Infarction Patients Treated With Primary Percutaneous Coronary Intervention

Ischemic Mitral Regurgitation
Montreal Heart Institute
Abbott Medical Devices

Terminated

Transcatheter Mitral Valve Repair for the Treatment of Mitral Valve Regurgitation In Heart Failure (The EVOLVE-MR Trial) (EVOLVE-MR)

Ventricular Remodeling, Left

Canada
UMC Utrecht

Terminated

Edwards SAPIEN-3 Periprosthetic Leakage Evaluation Versus Medtronic CoreValve in Transfemoral Aortic Valve Implantation (ELECT)

Periprosthetic Aortic Valve Regurgitation After TAVI

Netherlands
Seung-Jung Park
CardioVascular Research Foundation, Korea

Terminated

Evaluation of Effectiveness and Safety of Evolut R Valve In Patients With Pure Aortic Regurgitation (Pure AR TAVR)

Aortic Regurgitation | Aortic Valve Insufficiency | Regurgitation, Aortic Valve | Aortic Valve | Aortic Incompetence

Korea, Republic of
Myocor

Completed

RESTOR-MV: Randomized Evaluation of a Surgical Treatment for Off-Pump Repair of the Mitral Valve

Heart Failure | Mitral Valve Regurgitation | Left Ventricular Dysfunction

United States
Edwards Lifesciences

Completed

TRI-REPAIR: TrIcuspid Regurgitation RePAIr With CaRdioband Transcatheter System (TRI-REPAIR)

Heart Diseases | Cardiovascular Diseases | Heart Valve Diseases | Tricuspid Valve Regurgitation | Tricuspid Valve Insufficiency | Tricuspid Regurgitation | Cardiac Valve Annuloplasty

Italy, Germany, France
Icahn School of Medicine at Mount Sinai
National Heart, Lung, and Blood Institute (NHLBI); Canadian Institutes of Health... and other collaborators

Active, not recruiting

Evaluating the Benefit of Concurrent Tricuspid Valve Repair During Mitral Surgery

Tricuspid Regurgitation | Mild Tricuspid Regurgitation | Moderate Tricuspid Regurgitation

United States, Canada, Germany
Mayo Clinic

Recruiting

A Study to Evaluate a Computerized Stethoscope Called ©Voqx to Diagnose Heart Disease

Mitral Regurgitation | Isolated Aortic Stenosis

United States
National Institute of Cardiology, Warsaw, Poland
Medical Research Agency, Poland; Soft Communication, Poland

Enrolling by invitation

Optimal PeriproCeduraL AnticOagulation in Structural Transseptal Interventions (STOP CLOT)

Atrial Fibrillation | Mitral Regurgitation | Anticoagulation

Poland
Charite University, Berlin, Germany

Recruiting

Berlin Registry of Right Heart Interventions

Pulmonary Regurgitation | Tricuspid Regurgitation

Germany
TriFlo Cardiovascular, Inc.

Not yet recruiting

Transcatheter Treatment of Tricuspid Valve Regurgitation

Symptomatic Severe Tricuspid Regurgitation

Italy
The Cleveland Clinic
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Phenotypic Classification of FMR With CMR

Functional Mitral Regurgitation | Nonischemic Congestive Cardiomyopathy

United States
American College of Cardiology
The Society of Thoracic Surgeons

Recruiting

STS/ACC TVT Registry Mitral Module (TMVR)

Mitral Valve Regurgitation

United States
Karolinska Institutet
Karolinska University Hospital

Recruiting

Ventricular Arrhythmias in Patients Undergoing Mitral Valve Surgery (Mitra-VT)

Mitral Regurgitation | Ventricular Tachycardia | Mitral Valve Prolapse

Sweden
Abbott Medical Devices

Recruiting

PARADIGM: Amplatzer Valvular Plug for PVL Closure (PARADIGM)

Paravalvular Aortic Regurgitation

United States, Spain, Canada, Netherlands, United Kingdom, Italy, Poland
Assistance Publique - Hôpitaux de Paris

Unknown

Transcatheter Aortic Valve Implantation With Sapien 3 Transcatheter Heart Valve for Pure Aortic Regurgitation (S3AR)

Pure Aortic Regurgitation

France
Assistance Publique Hopitaux De Marseille

Suspended

Aortic Valve Regurgitation Acquired After Left Ventricular Assist Device Implantation: an Outstanding in Vivo Model of Valvular Heart Diseases

Aortic Valve Regurgitation Acquired

France
Baylor Research Institute
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Impact of Medical and Surgical Therapy on Functional Mitral Regurgitation

Heart Diseases | Cardiovascular Diseases | Coronary Disease

United States
Ankara University
The Scientific and Technological Research Council of Turkey

Unknown

Gene Expression Profiles in Patients With Permanent Atrial Fibrillation (AF) Versus Sinus Rhythm (SR)

Atrial Fibrillation | Mitral Regurgitation | Sinus Rhythm

Turkey
Genesis Medtech Corporation

Recruiting

Clinical Trial in China

Diseases of Aortic Valve | Aortic Regurgitation Disease

China
Mayo Clinic

Completed

Rhythm Control and Potential Early Surgery for Tricuspid Regurgitation

Severe Tricuspid Valve Regurgitation (Disorder)

United States

Clinical Trials on Mitral Valve Regurgitation

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