Clinical Trials on Moderate-severe Pain in Australia

Total 382 results

Peter MacCallum Cancer Centre, Australia
Melbourne Health; Westmead Hospital; Victorian Infectious Diseases Reference...

Completed

PET/CT and Bacterial/Fungal PCR in High Risk Febrile Neutropenia (PIPPIN)

Acute Myeloid Leukemia | Febrile Neutropenia | Acute Lymphoblastic Leukemia | Haematopoietic Stem Cell Transplant, Autologous | Haematopoietic Stem Cell Transplant, Allogeneic

Australia
Germano Melissano

Suspended

Cryoablation of Intercostal Nerves for Better Control of Postoperative Pain After Thoracic and Thoracoabdominal Open Surgery

Aneurysm

Netherlands, Germany, Italy, United Kingdom, Austria, France, Portugal, Switzerland
89bio, Inc.

Recruiting

To Evaluate the Efficacy and Safety of Pegozafermin in Subjects With Severe Hypertriglyceridemia (ENTRUST)

Severe Hypertriglyceridemia

United States, Bulgaria, Canada, Latvia, Spain, Austria, Belgium, Czechia, Georgia, Hungary, Poland, Puerto Rico, Argentina, Chile, France, Germany, United Kingdom, India, Italy
Octapharma

Completed

Efficacy and Safety Study of Human-cl rhFVIII in PTPs With Severe Hemophilia A

Severe Hemophilia A

Germany, Austria, United Kingdom, Bulgaria
Ionis Pharmaceuticals, Inc.

Active, not recruiting

A Study of Olezarsen (ISIS 678354) Administered to Participants With Severe Hypertriglyceridemia

Severe Hypertriglyceridemia

Finland, United States, France, Israel, Netherlands, Denmark, Spain, Australia, United Kingdom, Germany, Italy, Canada, Czechia, Turkey, Hungary, Bulgaria, New Zealand, Sweden, South Africa, Poland, Norway, Portugal, Slovakia
Abbott Medical Devices

Completed

A Post-Market Study Evaluating the Prodigy MRI and Proclaim Elite MR Conditional SCS Systems (SCS MRI PMCF)

Chronic Pain

Italy, United States, Belgium, Austria, Germany, Spain, United Kingdom
Starship Child Health, Te Toka Tumai Auckland
Menzies School of Health Research; Health Research Council, New Zealand

Not yet recruiting

TREAT-SC: Early, Short Course Oral Dexamethasone for the Treatment of Sydenham Chorea in Children (TREAT-SC)

Rheumatic Fever | Sydenham Chorea

Australia, New Zealand
GlaxoSmithKline

Completed

Study in Neuropathic Pain Patients With Peripheral Nerve Injury (PNI)

Pain, Neuropathic

Spain, Russian Federation, Sweden, Denmark, United Kingdom, Norway, Australia
Edwards Lifesciences

Recruiting

ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve

Aortic Stenosis, Severe

United States, Australia, New Zealand, Canada
Xeris Pharmaceuticals
Empiristat, Inc.

Completed

G-Pen Compared to Glucagen Hypokit for Severe Hypoglycemia Rescue in Adults With Type 1 Diabetes

Type 1 Diabetes Mellitus | Severe Hypoglycemia | Insulin Hypoglycemia

United States, Canada, Austria
Pfizer

Terminated

Placebo Controlled Dose-Response Study Of PD-217,014 In The Treatment Of Postherpetic Neuralgia

Pain

Australia, Spain, Canada, Czech Republic, Netherlands, United Kingdom
Grünenthal GmbH

Completed

Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Chronic Low Back Pain Taking Either WHO Step I or Step II Analgesics or no Regular Analgesics

Low Back Pain | Chronic Pain

Austria, Germany, United Kingdom, Croatia, France, Italy, Poland, Spain, Switzerland
Grünenthal GmbH

Completed

Tapentadol Prolonged Release (PR) Versus Oxycodone/Naloxone Prolonged Release in Severe Chronic Low Back Pain With a Neuropathic Component.

Back Pain | Low Back Pain | Neuropathic Pain

Germany, Spain, Austria, Italy
Bioverativ Therapeutics Inc.
Swedish Orphan Biovitrum

Completed

Study to Evaluate the Safety, Pharmacokinetics and Efficacy of Recombinant Factor VIII Fc Fusion Protein (rFVIIIFc) in Previously Treated Subjects With Severe Hemophilia A

Severe Hemophilia A

United States, United Kingdom, Spain, Hong Kong, Israel, New Zealand, Sweden, Australia, Brazil, Japan, Austria, Belgium, Italy, India, Switzerland, Canada, France, Germany, South Africa
MedtronicNeuro

Completed

SISTERS: Spasticity In Stroke Study - Randomized Study (SISTERS)

Severe Spasticity

Belgium, Spain, United States, Austria, Germany, Italy, Netherlands, Slovenia, United Kingdom
Grünenthal GmbH

Terminated

Evaluation of Effectiveness and Tolerability of Tapentadol Hydrochloride in Subjects With Severe Pain Due to Osteoarthritis Taking WHO Step III Analgesics But Showing a Lack of Tolerability.

Osteoarthritis | Chronic Pain

Germany, United Kingdom, Spain, Australia, Denmark, Poland
Amgen

Completed

Trial Assessing Long Term USe of PCSK9 Inhibition in Subjects With Genetic LDL Disorders (TAUSSIG)

Severe Familial Hypercholesterolemia

Italy, Czechia, United States, Israel, New Zealand, South Africa, France, Spain, Australia, Belgium, Canada, Netherlands, Hong Kong, Brazil, United Kingdom, Greece, Japan, Lebanon
Christian Müller, MD
University Hospital Inselspital, Berne; Medical University Innsbruck; University... and other collaborators

Recruiting

Reliability of Cardiac Troponins for the Diagnosis of Myocardial Infarction in the Presence of Skeletal Muscle Disease (H&M)

Muscle Weakness | Muscle Atrophy | Muscle Spasticity | Muscle Cramp | Muscle Soreness | Muscle Damage | Myopathy | Muscle Injury

Switzerland, Austria
Bioverativ Therapeutics Inc.
Swedish Orphan Biovitrum

Completed

Study of Recombinant Factor IX Fc Fusion Protein (rFIXFc) in Participants With Hemophilia B

Severe Hemophilia B

Sweden, United States, France, Italy, Russian Federation, United Kingdom, Germany, China, Poland, Japan, Australia, Brazil, Canada, India, South Africa, Hong Kong, Belgium
Grünenthal GmbH

Completed

Efficacy and Tolerability of Lidocaine Plaster for Treatment of Long-term Local Nerve Pain

Pain | Chronic Pain | Postoperative Pain | Neuropathic Pain

Austria, Belgium, Brazil, Denmark, France, Italy, Spain, United Kingdom
Axsome Therapeutics, Inc.

Unknown

CREATE-1: A Study to Assess the Efficacy and Safety of AXS-02 in Patients With CRPS-1 (CREATE-1)

Reflex Sympathetic Dystrophy | Complex Regional Pain Syndrome

United States, United Kingdom, Australia, Canada
Tris Pharma, Inc.

Completed

CORAL XT - Open-label Extension Trial of the CORAL Trial (CORAL XT)

Neoplasms | Pain | Chronic Pain

Austria, Belgium, Bulgaria, Denmark, Germany, Hungary, Poland, Romania, Serbia, Slovakia
Grünenthal GmbH

Completed

Comparison of Increasing Doses of Tapentadol Versus a Combination of Tapentadol and Pregabalin

Low Back Pain | Neuropathic Pain

Austria, Belgium, Denmark, Germany, Netherlands, Poland, Spain
Themis Bioscience GmbH

Completed

Phase II Study to Evaluate Safety and Immunogenicity of a Chikungunya Vaccine (MV-CHIK-202)

Chikungunya Virus Infection

Austria, Germany
University of Alberta

Completed

Acupuncture for Preterm Infants Requiring Eye-exam (MAGNIFIC-ROP)

Pain | Retinopathy of Prematurity | Acupuncture | Premature Infant

Canada, Australia, Malaysia
Medical University of Vienna

Completed

Tonsillectomy Using BiZact™ - a Randomized Side-controlled Clinical Trial

Hemorrhage | Otorhinolaryngologic Diseases | Postoperative Pain | Surgery--Complications | Postoperative Hemorrhage | Tonsillectomy | Tonsillitis Chronic | Handling

Austria
University of Minnesota
National Institute of Allergy and Infectious Diseases (NIAID); National Institutes...

Recruiting

Respiratory Virus Hospitalization Study (FLU 003 Plus)

Influenza | Novel Respiratory Virus-1 Middle Eastern Respiratory Syndrome Coronavirus (MERS-CoV) | Novel Respiratory Virus-2 Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)

United States, Australia, Spain, Denmark, Greece, Argentina, United Kingdom, Belgium, Chile, Germany, Peru, Thailand
Octapharma

Completed

Assess the Safety and Efficacy of Individually Tailored Prophylaxis With Human-cl rhFVIII in Patients With Severe Haemophilia A

Severe Haemophilia A

Austria, United Kingdom, Bulgaria, Hungary, Germany, Poland, Romania, Slovakia
Abbott Medical Devices

Active, not recruiting

The CONFIDENCE Registry

Severe Aortic Stenosis | Symptomatic Degenerative Aortic Stenosis

Spain, Italy, United Kingdom, Germany, Switzerland, Czechia, Australia, Belgium, Poland
Tris Pharma, Inc.
Forest Laboratories

Completed

Efficacy and Safety of GRT6005 in Patients With Chronic Low Back Pain.

Low Back Pain

Austria, Belgium, Denmark, Finland, Germany, Hungary, Netherlands, Poland, Spain, Sweden, United Kingdom
Astellas Pharma Europe Ltd.

Completed

Observation of the Use of QUTENZA™ in Standard Clinical Practice (ASCEND)

Peripheral Neuropathic Pain

Austria, Greece, Italy, Portugal, Spain, Switzerland, United Kingdom
Bioverativ Therapeutics Inc.

Completed

Long-Term Safety and Efficacy of rFIXFc in the Prevention and Treatment of Bleeding Episodes in Previously Treated Participants With Hemophilia B (B-YOND)

Severe Hemophilia B

United States, Italy, Belgium, Australia, Brazil, Hong Kong, India, Ireland, Japan, South Africa, United Kingdom, Netherlands, Sweden, Canada, Poland, China, France, Germany
Biogen

Terminated

Extension Study to Evaluate the Long-Term Safety, Tolerability, and Maintenance of Effect of BIIB074 (RELAY-1 Extend)

Neuropathic Pain From Lumbosacral Radiculopathy

Spain, United Kingdom, Slovakia, Austria, Belgium, Bulgaria, Czechia, France, Georgia, Italy, Latvia, Romania, Serbia, Estonia
Bionorica SE
FGK Clinical Research GmbH

Recruiting

Efficacy of Vitex Agnus-castus BNO 1095 (20 mg) in Women With Primary Dysmenorrhea

Primary Dysmenorrhea

Poland, Hungary, Germany, Czechia, Austria, Sweden
Medical University of Vienna
Paracelsus Medical University

Completed

Growth and Weight Gain in ELBW Infants Fed an Exclusively Human Milk Based Diet With Prolacta®

Preterm Infants | Weight Gain | Human Milk | Extremely Low Birth Weight

Austria
Grünenthal GmbH
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

Completed

A Study to Evaluate Tapentadol (CG5503) in the Treatment of Chronic Tumor-Related Pain Compared With Placebo and Morphine

Pain | Tumor

Austria, Bulgaria, Croatia, Czechia, France, Germany, Hungary, Italy, Moldova, Republic of, Poland, Romania, Russian Federation, Serbia, Slovakia, Spain, Sweden
CSL Behring

Completed

An Open-label Safety and Efficacy Study of Recombinant FVIII in Patients With Severe Hemophilia A

Hemophilia A | Severe Hemophilia A

United States, Australia, Austria, Canada, Czechia, France, Georgia, Germany, Hungary, Ireland, Italy, Japan, Lebanon, Malaysia, Netherlands, Philippines, Poland, Portugal, Romania, South Africa, Spain, Switzerland, Thailand, Ukraine, United...
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Efficacy and Safety of Gefapixant (MK-7264) in Women With Endometriosis-Related Pain (MK-7264-034)

Endometriosis-related Pain

United States, Australia, Chile, New Zealand, Poland, Puerto Rico, Russian Federation, Spain, Ukraine
Tris Pharma, Inc.

Terminated

CORAL - Cebranopadol Versus Morphine Prolonged-release in Patients With Chronic Moderate to Severe Pain Related to Cancer (CORAL)

Neoplasms | Pain | Chronic Pain

Croatia, Austria, Belgium, Bulgaria, Denmark, Germany, Hungary, Poland, Romania, Serbia, Slovakia, Chile, Spain, United Kingdom
Alza Corporation, DE, USA

Terminated

A Prospective Safety Surveillance Study of Fentanyl Iontophoretic Transdermal System (40 Mcg)

Pain

Germany, Austria, Finland, Netherlands
Mesoblast, Ltd.
Quintiles, Inc.

Completed

Placebo-controlled Study to Evaluate Rexlemestrocel-L Alone or Combined With Hyaluronic Acid in Participants With Chronic Low Back Pain (MSB-DR003)

Degenerative Disc Disease

United States, Australia
Novartis Vaccines

Completed

Safety of Two Trivalent Influenza Vaccines Evaluated in Children and Adolescents 4 to 17 Years of Age

Fever | Influenza

United States, Australia, New Zealand, Philippines, Thailand
Dompé Farmaceutici S.p.A

Recruiting

Reparixin add-on Therapy to Std Care to Limit Progression in Pts With COVID19 & Other Community Acquired Pneumonia

Severe COVID-19 | Infectious Pneumonia

United States, Australia, Turkey, Argentina, Germany, Austria, Italy
Newron Pharmaceuticals SPA

Completed

Phase II Dose Titration Study in Patients With Neuropathic Pain

Neuropathic Pain

United Kingdom, Czech Republic, Poland, Italy, India, Austria
Jazz Pharmaceuticals
Otsuka Pharmaceutical Development & Commercialization, Inc.

Completed

Long Term Safety of Sativex Oromucosal Spray (Sativex®; Nabiximols) as Adjunctive Therapy in Patients With Uncontrolled Persistent Chronic Cancer Related Pain

Pain | Advanced Cancer

Italy, United States, Taiwan, United Kingdom, Czechia, Bulgaria, Belgium, Latvia, Mexico, Lithuania, Poland, Romania, Hungary, Spain, Israel, Germany, Puerto Rico, Australia
Swedish Orphan Biovitrum
Syneos Health

Active, not recruiting

A Study Evaluating Physical Activity and Joint Health in Severe Haemophilia A Patients ≥12 Years Treated Once Weekly With Efanesoctocog Alfa (FREEDOM)

Hemophilia A, Severe

Germany, Spain, France, Czechia, Netherlands, Ireland, Austria, Croatia, Greece, Italy, Norway, Slovenia, Sweden, United Kingdom
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Surgical Pain After Inguinal Hernia Repair (SPAIHR)

Pain, Postoperative | Hernia, Inguinal

United States, India, Spain, Australia, Canada, Sweden
Pfizer

Completed

A Study Comparing the Efficacy and Safety of Valdecoxib Plus Parecoxib Versus Valdecoxib Plus Placebo for the Treatment of Pain After Coronary Artery Bypass Surgery

Pain

Canada, United States, Belgium, Italy, Spain, Sweden, Colombia, Germany, Poland, Australia, Netherlands, Switzerland, Israel, Denmark, Singapore, South Africa, Ireland, United Kingdom, Czech Republic, Finland, Slovakia, Argentina, A... and more
VASCage GmbH
Medical University Innsbruck; Tirol Kiniken GmbH

Completed

Early Vascular Ageing in the YOUth (EVA4YOU)

Cardiovascular Diseases | Vascular Diseases | Hypertension | Obesity | Overweight | Sleep Disorder | Atherosclerosis | Sleep | Headache | Vascular Stiffness | Cardiovascular Risk Factor | Non-Alcoholic Fatty Liver Disease | Life Style | Cardiovascular Pathology

Austria
Johnson & Johnson Pharmaceutical Research & Development...
Grünenthal GmbH

Completed

An Open-label Extension Study With Flexible Dosing of Extended-release (ER) Tapentadol (CG5503) to Treat Patients With Moderate to Severe Chronic Pain

Pain | Osteoarthritis | Low Back Pain

United States, Australia, Canada, New Zealand

Clinical Trials on Moderate-severe Pain in Australia

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