Clinical Trials on Motor Disorders

Total 145735 results

Sun Yat-sen University
Shenzhen Nanshan Center for Chronic Disease Control

Recruiting

Nanshan Elderly Cohort Study (NECS)

Cardiovascular Diseases | Stroke | Hypertension | Obesity | Cancer | Type 2 Diabetes Mellitus | Death | Metabolic Syndrome | Chronic Kidney Disease | Sarcopenia

China
Massachusetts General Hospital

Recruiting

Open Lung Strategy, Gas Distribution and Right Heart Function in ARDS Patients

Respiratory Distress Syndrome | Mechanical Ventilation Complication | Right Ventricular Dysfunction | ARDS, Human | Right Heart Failure | Lung Injury, Acute | Alveolar Edema

United States
University Hospital, Toulouse

Recruiting

Alveolar Recruitment Maneuvers, Intracerebral Hemodynamic and Oxygenation (M'RHICO)

Acute Respiratory Distress Syndrome (ARDS) | Cerebral Injuries

France
University of Sao Paulo General Hospital

Completed

POST-CABGDM: Empagliflozin in Perioperative CABG (POST-CABGDM)

Coronary Artery Disease | Diabetes Mellitus, Type 2 | Acute Kidney Injury | Coronary Artery Bypass Surgery

Brazil
Imunon

Active, not recruiting

Study of IMNN-001 (Also Known as GEN-1) With NACT for Treatment of Ovarian Cancer (OVATION 2) (OVATION 2)

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Cancer

United States, Canada
Yale University
R-Pharm-US, LLC

Completed

Evaluation of Weekly Ixabepilone With or Without Biweekly Bevacizumab

Fallopian Tube Cancer | Epithelial Ovarian Cancer | Primary Peritoneal Cancer

United States
Pfizer

Terminated

Study of Maplirpacept (PF-07901801) in Combination With PLD in Patients With Platinum-Resistant Ovarian Cancer

Ovarian Neoplasms | Ovarian Cancer | Fallopian Tube Cancer | Epithelial Ovarian Cancer | Ovarian Carcinoma | Primary Peritoneal Carcinoma

United States
University of Texas Southwestern Medical Center
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Completed

Improving Chronic Disease Management With Pieces (ICD-Pieces)

Hypertension | Diabetes | Type 2 Diabetes | Chronic Kidney Disease | High BP

United States
The Hospital for Sick Children
University of Alberta; University of Waterloo

Terminated

Metformin Treatment in Infants After Perinatal Brain Injury

Premature Birth | Hypoxic Ischemic Encephalopathy of Newborn

Canada
Peking University
National Natural Science Foundation of China

Active, not recruiting

Peking University Birth Cohort in Tongzhou (PKUBC-T)

Obesity | Anemia | Preterm Birth | Child Development | Gestational Diabetes | Mother-Infant Interaction | Gestational Hypertension | Pregnancy Outcomes | Health Problems in Pregnancy

China
Children's Hospital Medical Center, Cincinnati

Completed

Eculizumab to Treat Thrombotic Microangiopathy/Atypical Hemolytic Uremic Syndrome -Associated Multiple Organ Dysfunction Syndrome in Hematopoietic Stem Cell Transplant Recipients

Thrombotic Microangiopathies | Atypical Hemolytic Uremic Syndrome | Multiple Organ Dysfunction Syndrome

United States
Peter MacCallum Cancer Centre, Australia

Active, not recruiting

BEACON - ABC in Recurrent Platinum Resistant HGSOC (BEACON)

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Carcinoma

Australia
AstraZeneca
British Columbia Cancer Agency

Completed

Phase II Study of AZD2281 in Patients With Known BRCA Mutation Status or Recurrent High Grade Ovarian Cancer or Patients With Known BRCA Mutation Status/ Triple Neg Breast Cancer

Breast Cancer | Ovarian Carcinoma

Canada
Sandoz

Completed

A Crossover Bioequivalence Study of Olaparib Tablets, 150 mg (Lek Pharmaceuticals d.d.) and Lynparza® (Olaparib) Tablets 150 mg (AstraZeneca Pharmaceuticals LP), in Patients With BRCA Mutated Ovarian Cancer, Recurrent Ovarian Cancer or Metastatic Breast Cancer

Breast Cancer | Ovarian Cancer

India
Peking Union Medical College Hospital

Completed

Single-cell Landscape of BALF in Patients With Severe ARDS and CARDS

Covid19 | ARDS: Acute Respiratory Distress Syndrome

China
Gregory Yanik
Jazz Pharmaceuticals

Completed

Defibrotide Therapy for SARS-CoV2 (COVID-19) Acute Respiratory Distress Syndrome (ARDS)

COVID-19 | COVID | Acute Respiratory Distress Syndrome | Sars-CoV2

United States
Winthrop University Hospital

Withdrawn

Differential Characteristics of Neuropathy in Type 2 Diabetics With and Without Lower Extremity Wounds

Type 2 Diabetes | Diabetic Foot Ulcer | Diabetic Neuropathy

United States
University of Utah

Completed

Effect of IV Acetaminophen on Patients in the Neurocritical Care Unit

Post-operative Craniotomy Patients | Carotid Endarterectomy and Carotid Artery Stenosis Patients | Post-op Spine Patients Admitted to the NCCU | Endovascular Patients Undergoing Intracranial Intervention | Traumatic Brain Injuries NPO for at Least 12 Hours

United States
Karolinska Institutet
University of California, San Diego; The Swedish Research Council; University... and other collaborators

Terminated

Safety and Efficacy of Hyperbaric Oxygen for ARDS in Patients With COVID-19 (COVID-19-HBO)

COVID-19 | Cytokine Storm | SARS (Severe Acute Respiratory Syndrome) | Acute Respiratory Failure | ARDS, Human | Sars-CoV2

Sweden, Germany
Genelux Corporation

Completed

GL-ONC1 Oncolytic Immunotherapy in Patients With Recurrent or Refractory Ovarian Cancer

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Carcinomatosis

United States
Ohio State University Comprehensive Cancer Center

Active, not recruiting

Universal Endometrial Cancer DNA Sequencing for Detection of Lynch Syndrome and Personalized Care (OPTEC)

Lynch Syndrome | Relatives | Endometrial Carcinoma | Endometrial Adenocarcinoma

United States
Ward Photonics LLC

Terminated

Low-Level Laser Therapy Treatment of Lung Inflammation in Post-COVID-19 Recovery

COVID-19 | Acute Respiratory Distress Syndrome

United States
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Completed

Efficacy of Respiratory Physiotherapy on Severe ICU-admitted COVID-19 Patients.

COVID-19 Acute Respiratory Distress Syndrome

Italy
Enzyvant Therapeutics GmBH
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Completed

Thymus Transplantation Dose in DiGeorge #932

DiGeorge Syndrome | DiGeorge Anomaly | Complete DiGeorge Anomaly | Complete DiGeorge Syndrome

United States
Jesús González de la Aleja Tejera

Completed

Glutamine Supplement in MELAS (Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like Episodes) Syndrome

MELAS Syndrome

Spain
Teodoro Marcianò

Terminated

Risk Factors for COVID-19 Mortality (RF-COVID)

Acute Respiratory Distress Syndrome | COVID-19 Virus Infection | Population at Risk

Italy
ExcellaBio LLC

Terminated

Combination of Nivolumab and Ipilimumab in Breast, Ovarian and Gastric Cancer Patients

Gastric Cancer | Ovarian Cancer | Breast Cancer Female

United States
Istanbul University - Cerrahpasa (IUC)

Withdrawn

Comparison of Extra Vascular Lung Water Index in Covid-19 ARDS and "Typical"ARDS Patients

Covid19 | Respiratory Distress Syndrome, Adult | Pulmonary Edema | Ventilation Perfusion Mismatch

Turkey
Abliva AB

Completed

A Phase Ia/Ib, SAD and MAD Study of of KL1333 in Healthy Subjects and Patients With Primary Mitochondrial Disease

Mitochondrial Diseases | Mitochondrial Myopathies | MELAS Syndrome | Mitochondrial Respiratory Chain Deficiencies

United Kingdom
Unidad Temporal COVID-19 en Centro Citibanamex

Completed

Effects in Oxygenation and Hypoxic Pulmonary Vasoconstriction in ARDS Secondary to SARS-CoV2 (COVID-19)

Acute Respiratory Distress Syndrome | SARS-CoV-2 Acute Respiratory Disease | Hypoxemia | Hypoxic Pulmonary Vasoconstriction

Mexico
University of Zurich

Completed

Closed Loop Mechanical Ventilation and ECMO

Acute Respiratory Distress Syndrome | Cardiogenic Shock
University of Maryland, Baltimore

Withdrawn

Pilot RCT of Therapeutic Hypothermia Plus Neuromuscular Blockade in COVID-19 Patients With ARDS (CHILL-pilot)

Respiratory Distress Syndrome, Adult | Sars-CoV2

United States
University Hospital, Tours

Completed

Prone Position in Patients on High-flow Nasal Oxygen Therapy for COVID-19 (HIGH-PRONE-COVID-19)

COVID-19 | Acute Respiratory Distress Syndrome

France
University Hospital, Montpellier

Completed

Extra Vascular Lung Water and Pulmonary Permeability in Critically Ill Patients With SARS-CoV-2 (COVID-19) (PiCCOVID)

COVID-19 | Pneumonia | Acute Respiratory Distress Syndrome

France
Spectrum Pharmaceuticals, Inc

Completed

Topotecan Liposomes Injection for Small Cell Lung Cancer (SCLC), Ovarian Cancer and Other Advanced Solid Tumors

Small Cell Lung Cancer | Ovarian Cancer | Solid Tumors

United States
University of British Columbia
Medical University of Graz; Hospital de Clinicas de Porto Alegre

Unknown

Natural History of Morquio B and Late-Onset of GM1 Gangliosidosis

Morquio B Disease | GM1 Gangliosidosis Type III

Canada
Assiut University

Unknown

Neuromuscular Ultrasound in Correlation to Neurophysiological Findings

Diabetic Neuropathies | Carpal Tunnel Syndrome | Guillain-Barre Syndrome
Mayo Clinic
National Cancer Institute (NCI)

Completed

WEE1 Inhibitor AZD1775 With or Without Cytarabine in Treating Patients With Advanced Acute Myeloid Leukemia or Myelodysplastic Syndrome

Chronic Myelomonocytic Leukemia | Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Untreated Adult Acute Myeloid Leukemia | Myelodysplastic/Myeloproliferative Neoplasm | Myelodysplastic Syndrome With Isolated Del(5q)

United States
Catalysis SL

Completed

Oncoxin® and Quality of Life in Cancer Patients

Non-small Cell Lung Cancer Stage III | Gastric Cancer Stage III | Gastric Cancer Stage II | Non-small Cell Lung Cancer Stage II

Kazakhstan, Russian Federation
National Cheng-Kung University Hospital

Completed

Vascular Protective Effect of Rosuvastatin in Arteriovenous Fistula

Diabetes Mellitus | Arteriovenous Fistula | End-stage Kidney Disease

Taiwan
Pfizer

Terminated

A Study Of PF-06263507 In Patients With Advanced Solid Tumors

Neoplasms | Breast Neoplasms | Ovarian Neoplasms | Carcinoma, Non Small Cell Lung

United States
University Hospital, Montpellier
Centre Hospitalier Universitaire de Nīmes; University Hospital, Toulouse; Perpignan... and other collaborators

Terminated

Use Lay Language. CAA-ri : a Series of 28 Patients

Cerebral Amyloid Angiopathy Related Inflammation
AbbVie

Completed

A Study to Evaluate the Effects of Veliparib on Heart Rhythms in Patients With Solid Tumors

Breast Cancer | Gastric Cancer | Ovarian Cancer | Lung Cancer | Colon Cancer | Solid Tumors

United States, Netherlands, Spain
Rennes University Hospital

Unknown

Study of Immunity Dysfunction Induced by Extracorporeal Assistance (ECMO / ECLS) (IMPEC)

Acute Respiratory Distress Syndrome | Cardiogenic Shock

France
National Cancer Institute (NCI)

Withdrawn

CT-011 and p53 Genetic Vaccine for Advanced Solid Tumors

Sarcoma | Breast Cancer | Pancreatic Cancer | Ovarian Cancer | Colon Cancer

United States
GlaxoSmithKline

Completed

Second-line Intravenous Treatment For Recurrent Platinum-Sensitive Ovarian, Fallopian, Or Peritoneal Cancer

Ovarian Cancer | Fallopian Tube Cancer | Peritoneal Cancer | Neoplasms, Ovarian

United States, Canada
Centre hospitalier de l'Université de Montréal...

Completed

Comparison of Three Scores for Ultrasound Assessment and Monitoring of Pulmonary Aeration

Pneumonia | Acute Respiratory Distress Syndrome | Pulmonary Embolism | Dyspnea | Hypoxemia | Atelectasis

Canada
Novartis Pharmaceuticals

Completed

Imatinib Mesylate in Patients With Various Types of Malignancies Involving Activated Tyrosine Kinase Enzymes

Chronic Myelomonocytic Leukemia | Hypereosinophilic Syndrome | Systemic Mastocytosis | Dermatofibrosarcoma

Australia
Adelphi Values LLC
Blueprint Medicines Corporation

Completed

Patient-Reported Outcome Questionnaire for Systemic Mastocytosis

Mast Cell Leukemia (MCL) | Aggressive Systemic Mastocytosis (ASM) | SM w Assoc Clonal Hema Non-mast Cell Lineage Disease (SM-AHNMD) | Smoldering Systemic Mastocytosis (SSM) | Indolent Systemic Mastocytosis (ISM) ISM Subgroup Fully Recruited

United States
Amgen

Completed

TRINOVA-1: A Study of AMG 386 or Placebo, in Combination With Weekly Paclitaxel Chemotherapy, as Treatment for Ovarian Cancer, Primary Peritoneal Cancer and Fallopian Tube Cancer

Ovarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Cancer

United States, France, Italy, Spain, United Kingdom, Belgium, Canada, Poland, Switzerland, Korea, Republic of, Russian Federation, Hong Kong, Portugal, South Africa, Israel, Romania, Bulgaria, Greece, Australia, Sweden, Japan, Latvia and more

Clinical Trials on Motor Disorders

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