Clinical Trials on Multiple Myeloma Progression

Total 13469 results

Imperial College London
GlaxoSmithKline; University College, London; Medical Research Council; Queen Mary... and other collaborators

Completed

Patient Research Cohort: Rapidly Evolving Multiple Sclerosis (PRC-REMS)

Relapsing-remitting Multiple Sclerosis | Secondary Progressive Multiple Sclerosis

United Kingdom
Multiple Myeloma Research Consortium

Not yet recruiting

Horizon Adaptive Platform Trial Evaluating Therapies in RRMM

Refractory Multiple Myeloma | Relapse Multiple Myeloma
Massachusetts General Hospital
Pfizer

Recruiting

Elranatamab in R/R Multiple Myeloma

Multiple Myeloma | Refractory Multiple Myeloma | Relapse Multiple Myeloma

United States
Carl Ola Landgren, MD, PhD
Bristol-Myers Squibb

Recruiting

Iberdomide, Daratumumab, Carfilzomib, and Dexamethasone (Iber-KDd) in Patients With Relapsed/Refractory Multiple Myeloma (Iber-KDd)

Refractory Multiple Myeloma | Relapsed Multiple Myeloma

United States
Pfizer

Recruiting

A Study to Learn How Patients With Triple Class Refractory Multiple Myeloma (TCR-MM) Are Treated in Italian Centers for Blood Related Diseases (MUST)

Refractory Multiple Myeloma | Relapse Multiple Myeloma

Italy
Shenzhen University General Hospital

Recruiting

B Cell Maturation Antigen Targeted CAR-T Cells in Treatment With Relapsed and Refractory Multiple Myeloma

Multiple Myeloma | Refractory Multiple Myeloma | Relapse Multiple Myeloma

China
Zhejiang University
Yake Biotechnology Ltd.

Not yet recruiting

A Study of Humanized BCMA-targeted CAR-T Cells Therapy for Refractory/Relapsed Multiple Myeloma

Refractory Multiple Myeloma | Relapse Multiple Myeloma

China
Amgen

Completed

Study of Carfilzomib, Daratumumab and Dexamethasone for Patients With Relapsed and/or Refractory Multiple Myeloma. (CANDOR)

Refractory Multiple Myeloma | Relapsed Multiple Myeloma

Canada, Belgium, Spain, United States, Korea, Republic of, Australia, Czechia, Taiwan, Hungary, Austria, Romania, Japan, United Kingdom, Greece, Turkey, Bulgaria, France, Russian Federation, Poland
Mario Boccadoro

Active, not recruiting

Evaluation of the Safety and the Efficacy of Carfilzomib Combined With Cyclophosphamide and Dexamethasone (CCyd) or Lenalidomide and Dex (CRd) Followed by ASCT or 12 Cycles of Carf Combined With Dex and Len for Patients Eligible for ASCT With Newly Diagnosed Multiple Myeloma. (FORTE)

MULTIPLE MYELOMA (MM)

Italy
Regeneron Pharmaceuticals

Active, not recruiting

First In Human (FIH) Study of REGN5459 in Adult Patients With Relapsed or Refractory Multiple Myeloma (MM)

Refractory Multiple Myeloma | Relapsed Multiple Myeloma

United States
Black Sea Hematology Association
Amgen

Unknown

Carfilzomib in Combination for the Treatment of RR MM

Multiple Myeloma | Refractory Multiple Myeloma | Relapse Multiple Myeloma

Turkey
Dana-Farber Cancer Institute
Beth Israel Deaconess Medical Center; Brigham and Women's Hospital; H. Lee Moffitt...

Completed

Bortezomib in Combination With CC-5013 in Patients With Relapsed/Refractory Multiple Myeloma

Multiple Myeloma | Refractory Multiple Myeloma | Relapsed Multiple Myeloma

United States
Hoffmann-La Roche

Active, not recruiting

A Phase III, Non-Inferiority, Randomized, Open-Label, Parallel Group, Multicenter Study To Investigate The Pharmacokinetics, Pharmacodynamics, Safety And Radiological And Clinical Effects Of Subcutaneous Ocrelizumab Versus Intravenous Ocrelizumab In Patients With Multiple Sclerosis (Ocarina II)

Relapsing Multiple Sclerosis | Primary Progressive Multiple Sclerosis

Spain, United States, Italy, Poland, Turkey, New Zealand, Czechia, Brazil
Zhejiang University
Yake Biotechnology Ltd.

Recruiting

A Study of BCMA-targeted CAR-T Cells Therapy for Refractory/Relapsed Multiple Myeloma

Refractory Multiple Myeloma | Relapse Multiple Myeloma

China
Weill Medical College of Cornell University
Janssen Scientific Affairs, LLC

Recruiting

A Phase II Study of Daratumumab, Clarithromycin, Pomalidomide And Dexamethasone (D-ClaPd) In Multiple Myeloma Patients Previously Exposed to Daratumumab

Multiple Myeloma | Refractory Multiple Myeloma | Relapse Multiple Myeloma

United States
Ionis Pharmaceuticals, Inc.

Active, not recruiting

A Study of ION251 Administered to Patients With Relapsed/Refractory Multiple Myeloma

Refractory Multiple Myeloma | Relapsed Multiple Myeloma

United States
Takeda

Completed

A Phase 3 Study Comparing Oral Ixazomib Plus Lenalidomide and Dexamethasone Versus Placebo Plus Lenalidomide and Dexamethasone in Adult Participants With Relapsed and/or Refractory Multiple Myeloma

Refractory Multiple Myeloma | Relapsed Multiple Myeloma

United States, Canada
Ajai Chari
Amgen

Completed

Study of High Dose Carfilzomib in Multiple Myeloma Patients Who Have Progressed On Standard Dose Carfilzomib

Refractory Multiple Myeloma | Relapse Multiple Myeloma

United States
Amsterdam UMC, location VUmc

Recruiting

Discontinuing Disease-modifying Therapies in Stable Relapsing - Onset Multiple Sclerosis (DOT-MS). (DOT-MS)

Multiple Sclerosis | Multiple Sclerosis, Relapsing-Remitting | Multiple Sclerosis, Secondary Progressive

Netherlands
Danish Research Centre for Magnetic Resonance
Scleroseforeningen; Danish Multiple Sclerosis Center

Completed

Cortical Lesions in Patients With Multiple Sclerosis (CLiMS)

Multiple Sclerosis | Multiple Sclerosis, Relapsing-Remitting | Multiple Sclerosis, Secondary Progressive

Denmark
AB Science

Recruiting

Masitinib in the Treatment of Patients With Primary Progressive or Non-active Secondary Progressive Multiple Sclerosis (MAXIMS)

Progressive Multiple Sclerosis

Spain, Sweden, France, Greece, Italy, Poland, Russian Federation, Ukraine
Genzyme, a Sanofi Company

Completed

A Long-term Follow-up Study Of Multiple Sclerosis Patients Who Participated In Genzyme-sponsored Studies of GZ402668

Progressive Multiple Sclerosis

Germany
Somogy Megyei Kaposi Mór Teaching Hospital

Completed

Follow-up Study of the Effectiveness of Virtual Reality Therapy in MS Patients

Multiple Sclerosis, Chronic Progressive | Multiple Sclerosis, Primary Progressive

Hungary
NYU Langone Health

Completed

A Pilot Trial of Remotely-Supervised Transcranial Direct Current Stimulation (RS-tDCS) to Enhance Motor Learning in Progressive Multiple Sclerosis (MS)

Multiple Sclerosis

United States
IRCCS San Raffaele
Fondazione Italiana Sclerosi Multipla

Completed

Neural Stem Cell Transplantation in Multiple Sclerosis Patients (STEMS)

Progressive Multiple Sclerosis

Italy
Aristotle University Of Thessaloniki
Greek Alzheimer's Association and Related Disorders; Ellis-Farm, Eliama Daily...

Completed

Efficacy of Early Harvest Olive Oil in Cognition of Primary (PPMS) or Secondary (SPMS) Progressive Multiple Sclerosis

Progressive Multiple Sclerosis

Greece
Rigshospitalet, Denmark
Biogen

Completed

Dimethyl Fumarate Treatment of Primary Progressive Multiple Sclerosis (FUMAPMS)

Primary Progressive Multiple Sclerosis

Denmark
MedDay Pharmaceuticals SA

Terminated

Effect of MD1003 in Progressive Multiple Sclerosis (SPI2) (SPI2)

Multiple Sclerosis

United States, Spain, Canada, Australia, United Kingdom, Belgium, Turkey, Czechia, Poland, Italy, Hungary, Germany, Sweden
South Valley University

Completed

Aerobic Exercises for Multiple Sclerosis

Multiple Sclerosis, Primary Progressive

Egypt
Genentech, Inc.

No longer available

Expanded Access Program for Ocrelizumab in Participants With Primary Progressive Multiple Sclerosis

Multiple Sclerosis

United States
Novartis Pharmaceuticals

Terminated

This Was an Open-label, Single-arm Extension Study (CFTY720D2306E1) to a Double-blind, Randomized Multicenter, Placebo-controlled, Parallel-group Core Study (CFTY720D2306) in PPMS. (INFORMS)

Primary Progressive Multiple Sclerosis

United States, Belgium, Poland, Germany, Hungary, Turkey, Spain, Australia, Canada, Czechia, Switzerland, United Kingdom, Netherlands, France, Italy, Denmark, Finland, Sweden
Genentech, Inc.

Completed

Study to Explore the Mechanism of Action of Ocrelizumab and B-Cell Biology in Participants With Relapsing Multiple Sclerosis (RMS) or Primary Progressive Multiple Sclerosis (PPMS)

Multiple Sclerosis, Primary Progressive | Relapsing Multiple Sclerorsis

United States, Germany, Canada, Sweden
Bayer

Withdrawn

Study to Compare Double-dose Betaferon to the Approved Dose, for Patients With Early Secondary Progressive Multiple Sclerosis (SPMS)

Multiple Sclerosis

Sweden, Denmark
The First Affiliated Hospital of Xiamen University

Recruiting

All-trans Retinoic Acid in Combination With a KPD Regimen for the Treatment of Refractory/Relapsed Multiple Myeloma

Multiple Myeloma in Relapse | Multiple Myeloma, Refractory

China
Oncotherapeutics

Not yet recruiting

A Study of Venetoclax in Combination With Isatuximab and Dexamethasone for Relapsed/Refractory Multiple Myeloma

Multiple Myeloma in Relapse | Multiple Myeloma, Refractory
Dong-A University Hospital

Not yet recruiting

Carfilzomib, Oral Cyclophosphamide, and Dexamethasone for RRMM (KMM-KCd)

Multiple Myeloma in Relapse | Multiple Myeloma, Refractory
Amsterdam UMC, location VUmc

Not yet recruiting

Alternative Dosing Scheme of Pomalidomide 4 mg Every Other Day Versus Pomalidomide 2 mg and 4 mg Every Day; the POMAlternative Study (POMAlternative)

Multiple Myeloma | Multiple Myeloma in Relapse | Multiple Myeloma, Refractory
Luminary Therapeutics
The Cleveland Clinic; Case Western Reserve University

Recruiting

LMY-920 for Treatment of Relapsed or Refractory Myeloma (LMY-920-002)

Multiple Myeloma in Relapse | Multiple Myeloma, Refractory

United States
Tel-Aviv Sourasky Medical Center
Weizmann Institute of Science

Recruiting

Cyclosporine in Combination With Carfilzomib and Dexamethasone in Relapsed Multiple Myeloma Refractory to Carfilzomib and High Expression of PPIA Gene in Myeloma Cells

Multiple Myeloma in Relapse | Multiple Myeloma, Refractory

Israel
Tel-Aviv Sourasky Medical Center

Recruiting

Ixazomib-pomalidomide-dexamethasone as Second or Third-line Combination Treatment for Patients With Relapsed and Refractory Multiple Myeloma Previously Treated With Daratumumab, Lenalidomide and Bortezomib (IPoD-790)

Refractory Multiple Myeloma | Multiple Myeloma in Relapse

Israel
Zhejiang University
Yake Biotechnology Ltd.

Recruiting

APRIL CAR-T Cell Therapy for Patients With BCMA/TACI Positive Relapsed and/or Refractory Multiple Myeloma

Multiple Myeloma in Relapse | Multiple Myeloma, Refractory

China
TJ Biopharma Co., Ltd.

Active, not recruiting

TJ202, Lenalidomide and Dexamethasone vs. Lenalidomide and Dexamethasone in Subjects With Relapsed or Refractory Multiple Myeloma

Refractory Multiple Myeloma | Multiple Myeloma in Relapse

China, Taiwan
TJ Biopharma Co., Ltd.

Active, not recruiting

TJ202 Combined With Dexamethasone in Subjects With Relapsed or Refractory Multiple Myeloma

Refractory Multiple Myeloma | Multiple Myeloma in Relapse

China, Taiwan
Alliance Foundation Trials, LLC.
Pharmacyclics LLC.

Active, not recruiting

Study of Ibrutinib in Combination With Revlimid/Dexamethasone in Relapsed/Refractory Multiple Myeloma

Multiple Myeloma | Refractory Multiple Myeloma | Multiple Myeloma in Relapse

United States
National Cancer Institute (NCI)

Terminated

Aflibercept for Relapsed Multiple Myeloma

Stage II Multiple Myeloma | Stage III Multiple Myeloma

United States
Ajai Chari
Celgene Corporation

Completed

Study of Pomalidomide, Cyclophosphamide, Dexamethasone in Relapsed/Refractory Multiple Myeloma

Multiple Myeloma in Relapse | Multiple Myeloma, Refractory

United States
Instituto Universitario de Oftalmobiología Aplicada...
Hospital del Río Hortega; Fundación Eugenio Rodríguez Pascual

Enrolling by invitation

Visual Processing Speed and Objective Analysis of Ocular Movements in Multiple Sclerosis

Progressive Multiple Sclerosis | Multiple Sclerosis | Clinically Isolated Syndrome | Relapsing Remitting Multiple Sclerosis

Spain
University Hospital, Caen

Active, not recruiting

Neuropsychological Management of Multiple Sclerosis: Benefits of a Computerised Semi-autonomous At-home Cognitive Rehabilitation Programme (SEPIA)

Relapsing Remitting Multiple Sclerosis | Secondary Progressive Multiple Sclerosis

France
National Cancer Institute (NCI)

Active, not recruiting

T Cells Expressing a Novel Fully-Human Anti-BCMA CAR for Treating Multiple Myeloma

Myeloma-Multiple | Myeloma, Plasma-Cell

United States
National Cancer Institute (NCI)

Completed

Study of T Cells Targeting B-Cell Maturation Antigen for Previously Treated Multiple Myeloma

Myeloma-Multiple | Myeloma, Plasma-Cell

United States

Clinical Trials on Multiple Myeloma Progression

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