Clinical Trials on Muscle Spasticity in Ireland

Total 73 results

Allergan

Completed

BOTOX® Treatment in Pediatric Lower Limb Spasticity

Cerebral Palsy | Muscle Spasticity | Pediatrics

United States, Korea, Republic of, Thailand, Hungary, Italy, Philippines, Poland, Russian Federation, Turkey
Allergan

Completed

BOTOX® Open-Label Treatment in Pediatric Lower Limb Spasticity

Cerebral Palsy | Muscle Spasticity | Pediatrics

United States, Korea, Republic of, Thailand, Philippines, Poland, Hungary, Russian Federation, Turkey, Italy
Nuritas Ltd
Sports Surgery Clinic, Santry, Dublin

Completed

Effects of Protein Hydrolysate Supplementation Influencing Strength Recovery and Expression of Muscle Damage Markers Post-exercise

Muscle Injury

Ireland
Nuritas Ltd

Completed

Effects of Protein Hydrolysate Supplement on Systemic Muscle Function Markers Following Resistance Type Exercise in Male Subjects

Muscle Injury

Ireland
University of Limerick

Unknown

Protein Supplementation and Recovery of Muscle Function

Muscle Damage | Resistance Training

Ireland
Naturex SA
Atlantia Food Clinical Trials

Completed

Recovery and Muscle Function After Supplementation With Turmeric (RECOFAST)

Pain | Muscle Soreness | Muscle Damage

Ireland
University of Limerick

Completed

Whey Protein Support to Metabolic and Performance Adaptations in Response HIIT

Exercise | Muscle, Skeletal | High-Intensity Interval Training

Ireland
Elan Pharmaceuticals

Completed

Comparison of Safety and Efficacy of Tizanidine Hydrochloride Capsules Versus Zanaflex® (Tizanidine Hydrochloride Tablets) Taken While in the Fed State (Just After a Meal) and in the Fasted State (Before a Meal) in Patients With Moderate to Severe Spasticity.

Stroke | Multiple Sclerosis | Muscle Spasticity | Spinal Cord Injury

United States
University College Cork
South East Technological University

Completed

RubusElite Efficacy Testing of a Novel High Protein, Berry Polyphenol Enriched Dairy Beverage

Stress | Anxiety | Muscle Soreness | Muscle Damage | Exercise Performance | Gut Microbiome

Ireland
Bio-Medical Research, Ltd.

Completed

Determination of the Efficacy of Slendertone® Face to Tone the Muscles of the Face and Reduce the Signs of Facial Aging (Face)

Facial Muscle Toning

Ireland
Royal College of Surgeons, Ireland
St. James's Hospital, Ireland

Completed

Lower Limb Resistance Training in Older Inpatients

Muscle Weakness

Ireland
University College Dublin
Kerry Group

Completed

Probiotic-Muscle Study

Muscle Weakness | Old Age; Debility | Protein Deposition | Protein Deregulation

Ireland
The Adelaide and Meath Hospital, incorporating...

Completed

Does Saline Injection Around Phrenic Nerve Reduce Incidence of Diaphragmatic Paresis Following Interscalene Block?

Phrenic Nerve Palsy

Ireland
Cynosure, Inc.

Completed

Study To Evaluate The Safety And Efficacy Of The MyEllevate® Procedure

Soft Tissue Approximation | Elevation of Subdermis | Elevation of Underlying Muscle

United States
University of Dublin, Trinity College
Motor Neurone Disease Association, UK; Irish Research Council, IE; Thierry Latran... and other collaborators

Recruiting

Non-invasive Spinal, Cortical, and Sensorimotor Biomarkers in Motor Neurone Disease

Multiple Sclerosis | Primary Lateral Sclerosis | Postpoliomyelitis Syndrome | Motor Neuron Disease, Amyotrophic Lateral Sclerosis | Motor Neuron Disease Progressive Spinal Muscle Atrophy

Ireland
European Paediatric Soft Tissue Sarcoma Study Group
Children's Cancer and Leukaemia Group; Dutch Childhood Oncology Group; Italian...

Unknown

Combination Chemotherapy in Treating Young Patients With Nonmetastatic Rhabdomyosarcoma

Sarcoma

Ireland, United Kingdom, Spain, Belgium, Austria, Denmark, Sweden, Switzerland
University of Saskatchewan

Completed

Delivra Topical Creatine for Improving Muscular Power

Muscle Weakness

Canada
University of Saskatchewan
University of Guelph; University of Prince Edward Island

Completed

Delivra Topical Creatine Combined With Oral Creatine for Improving Muscular Power

Muscle Weakness

Canada
Neurana Pharmaceuticals, Inc.

Completed

Efficacy and Safety of Tolperisone in Subjects With Pain Due to Acute Back Muscle Spasm (RESUME-1)

Back Pain | Acute Pain | Back Muscle Spasm | Back Strain | Back Spasm Upper | Muscle Spasm

United States
Societe Internationale d'Oncologie Pediatrique
Children's Cancer and Leukaemia Group; Societe Francaise Oncologie Pediatrique

Completed

Combination Chemotherapy in Treating Children With Metastatic Rhabdomyosarcoma or Other Malignant Mesenchymal Tumors

Sarcoma | Small Intestine Cancer | Ovarian Cancer

France, United Kingdom, Ireland
Pfizer

Terminated

A Study to Learn About the Study Medicine (Called Ontorpacept or TTI-621) Given Alone and in Combination With Doxorubicin in People With Leiomyosarcoma (TTI-621-03)

Leiomyosarcoma

United States
Brown University
Actuate Therapeutics Inc.

Withdrawn

A Phase 2 Study of 9-ING-41Combined With Chemotherapy in Adolescents and Adults With Advanced Sarcomas

Sarcoma | Soft Tissue Sarcoma | Leiomyosarcoma | High Grade Sarcoma | Liposarcoma | Rhabdomyosarcoma | Angiosarcoma | Bone Sarcoma | Synovial Sarcoma | Undifferentiated Pleomorphic Sarcoma | Metastatic Sarcoma | Myxofibrosarcoma | Spindle Cell Sarcoma

United States
University of Chicago
Myovant Sciences GmbH

Recruiting

Surgical Myomectomy Followed by Oral Myfembree Versus Standard of Care Trial (SOUL) (SOUL)

Pelvic Pain | Metrorrhagia | Leiomyoma | Menorrhagia

United States
Neurana Pharmaceuticals, Inc.

Completed

Tolperisone in Acute Muscle Spasm of the Back (STAR)

Back Pain | Low Back Pain | Acute Pain | Muscle Cramp | Back Strain | Muscle Spasm | Back Spasm Upper Back

United States
University of Birmingham

Recruiting

FaR-RMS: An Overarching Study for Children and Adults With Frontline and Relapsed RhabdoMyoSarcoma (FaR-RMS)

Rhabdomyosarcoma

Switzerland, Spain, Denmark, United Kingdom, France, Israel, Australia, New Zealand, Austria, Belgium, Greece, Ireland, Italy, Netherlands, Norway, Portugal, Slovakia, Slovenia, Czechia
Brown University
Actuate Therapeutics Inc.

Withdrawn

Phase 2 Study of 9-ING-41 With Chemotherapy in Sarcoma

Soft Tissue Sarcoma | Osteosarcoma | Ewing Sarcoma of Bone | Leiomyosarcoma | High Grade Sarcoma | Liposarcoma | Rhabdomyosarcoma | Angiosarcoma | Bone Sarcoma | Synovial Sarcoma | Undifferentiated Pleomorphic Sarcoma | Myxofibrosarcoma | Spindle Cell Sarcoma

United States
Merck Sharp & Dohme LLC
Seagen Inc.; Astellas Pharma Global Development, Inc.

Recruiting

Perioperative Pembrolizumab (MK-3475) Plus Cystectomy or Perioperative Pembrolizumab Plus Enfortumab Vedotin Plus Cystectomy Versus Cystectomy Alone in Participants Who Are Cisplatin-ineligible or Decline Cisplatin With Muscle-invasive Bladder Cancer (MK-3475-905/KEYNOTE-905/EV-303)

Urinary Bladder Cancer, Muscle-invasive

United States, Australia, Belgium, Canada, Denmark, France, Germany, Hungary, Ireland, Israel, Italy, Korea, Republic of, Malaysia, Mexico, Philippines, Poland, Russian Federation, Singapore, South Africa, Spain, Sweden, Thailand, T... and more
Merck Sharp & Dohme LLC

Recruiting

Study of Pembrolizumab (MK-3475) and Pembrolizumab With Other Investigational Agents in Participants With High Risk Non-muscle Invasive Bladder Cancer (MK-3475-057/KEYNOTE-057)

Bladder Cancer

Canada, France, Italy, Netherlands, Turkey, Brazil, Spain, United States, Finland, Puerto Rico, Singapore
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Docetaxel, Gemcitabine, and Filgrastim (G-CSF) or Pegfilgrastim in Treating Patients With Advanced, Persistent, or Recurrent Uterine Leiomyosarcoma

Sarcoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma

Sarcoma

United States, Canada, Puerto Rico, Australia, Netherlands, New Zealand, Switzerland
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Metastatic Rhabdomyosarcoma or Sarcoma

Sarcoma

United States, Canada, Puerto Rico, Australia, Netherlands, New Zealand, Switzerland
Bayer

Terminated

Assess Safety and Efficacy of Vilaprisan in Subjects With Uterine Fibroids (ASTEROID 5)

Uterine Fibroids

Spain, Korea, Republic of, Denmark, Taiwan, Hungary, Lithuania, Austria, Portugal, Germany, Australia, Canada, Sweden, Bulgaria, Czechia, Finland, Norway, Poland, United Kingdom, Belgium, Italy, Slovakia, Netherlands, Ireland
European Organisation for Research and Treatment...
Canadian Cancer Trials Group; ECOG-ACRIN Cancer Research Group; Japan Clinical... and other collaborators

Recruiting

Surgery With or Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma (STRASS2)

Leiomyosarcoma | Liposarcoma | Retroperitoneal Sarcoma

United States, Japan, France, Spain, Canada, Italy, United Kingdom, Germany, Czechia, Cyprus, Netherlands, Australia, Poland, Slovakia, Denmark
Amzell

Withdrawn

A Study to Evaluate Safety and Efficacy of AMZ002 Treatment, Compared With Vigabatrin in Participants With Infantile Spasms

Spasms, Infantile

Italy, Argentina, France, United States, Spain, India, Poland, Mexico
Numab Therapeutics AG

Recruiting

NM32-2668 in Adult Patients With Selected Advanced Solid Tumors

Renal Cell Carcinoma | Mesothelioma, Malignant | Adenocarcinoma of Lung | Triple Negative Breast Cancer | Endometrial Cancer | Fallopian Tube Carcinoma | Peritoneal Carcinoma | Leiomyosarcoma | Liposarcoma | Ovarian Carcinoma | Adenocarcinoma of the Stomach | Melanoma, Malignant | Adenocarcinoma - Gastroesophageal...

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Terminated

Gemcitabine Hydrochloride and Docetaxel Followed by Doxorubicin Hydrochloride or Observation in Treating Patients With High-Risk Uterine Leiomyosarcoma Previously Removed by Surgery

Uterine Corpus Leiomyosarcoma | Stage I Uterine Sarcoma AJCC v7

United States, Belgium, France, Spain, United Kingdom, Netherlands, Norway, Venezuela
National Cancer Institute (NCI)
NRG Oncology

Completed

Alisertib in Treating Patients With Recurrent or Persistent Leiomyosarcoma of the Uterus

Recurrent Uterine Corpus Sarcoma | Uterine Corpus Leiomyosarcoma

United States
Bayer

Active, not recruiting

Assess Safety and Efficacy of Vilaprisan in Subjects With Uterine Fibroids (ASTEROID 6)

Uterine Fibroids

United States, China, Thailand, South Africa, Japan, Turkey, Czechia, Finland, Hong Kong, Mexico, Norway, Poland, Russian Federation
National Cancer Institute (NCI)
NRG Oncology

Completed

Ixabepilone in Treating Patients With Recurrent or Persistent Leiomyosarcoma of the Uterus Previously Treated With Chemotherapy

Recurrent Uterine Corpus Sarcoma | Uterine Corpus Leiomyosarcoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

Embryonal Rhabdomyosarcoma | Fusion-Negative Alveolar Rhabdomyosarcoma | Spindle Cell/Sclerosing Rhabdomyosarcoma

United States, Australia, Canada, New Zealand
Alexion Pharmaceuticals

Terminated

Safety and Efficacy Study of Eculizumab in Patients With Refractory Generalized Myasthenia Gravis

Myasthenia Gravis

United States, Canada, United Kingdom
ObsEva SA

Completed

Efficacy and Safety of OBE2109 in Subjects With Heavy Menstrual Bleeding Associated With Uterine Fibroids (PRIMROSE 1)

Uterine Fibroids | Heavy Menstrual Bleeding

United States
National Cancer Institute (NCI)

Active, not recruiting

Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk Rhabdomyosarcoma

Rhabdomyosarcoma | Alveolar Rhabdomyosarcoma | Embryonal Rhabdomyosarcoma | Botryoid-Type Embryonal Rhabdomyosarcoma | Sclerosing Rhabdomyosarcoma | Spindle Cell Rhabdomyosarcoma

United States, Canada, Puerto Rico, Australia, New Zealand
Sumitomo Pharma Switzerland GmbH

Recruiting

A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis

Endometriosis | Uterine Fibroids

United States
Hoffmann-La Roche

Recruiting

A Study of Atezolizumab Versus Placebo as Adjuvant Therapy in Patients With High-Risk Muscle-Invasive Bladder Cancer Who Are ctDNA Positive Following Cystectomy (IMvigor011)

Muscle-invasive Bladder Cancer

Belgium, Korea, Republic of, Japan, Brazil, China, United States, Singapore, France, United Kingdom, Canada, Greece, Italy, Spain, Turkey, Russian Federation, Ukraine, Israel, Czechia, Colombia, Hong Kong, Argentina, Germany, Ireland, Polan... and more
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

A Study to Compare Early Use of Vinorelbine and Maintenance Therapy for Patients With High Risk Rhabdomyosarcoma

Alveolar Rhabdomyosarcoma | Embryonal Rhabdomyosarcoma | Botryoid-Type Embryonal Rhabdomyosarcoma | Spindle Cell Rhabdomyosarcoma | Spindle Cell/Sclerosing Rhabdomyosarcoma | Metastatic Embryonal Rhabdomyosarcoma | Metastatic Rhabdomyosarcoma | Solid Alveolar Rhabdomyosarcoma

United States, Canada, Australia, Puerto Rico, Saudi Arabia
National Cancer Institute (NCI)

Recruiting

Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working

Locally Advanced Uterine Corpus Leiomyosarcoma | Metastatic Uterine Corpus Leiomyosarcoma | Stage III Uterine Corpus Leiomyosarcoma AJCC v8 | Stage IV Uterine Corpus Leiomyosarcoma AJCC v8 | Unresectable Uterine Corpus Leiomyosarcoma

United States, Puerto Rico
National Cancer Institute (NCI)

Recruiting

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder for Bladder Cancer Treatment, MODERN Study

Stage III Bladder Urothelial Carcinoma AJCC v6 and v7 | Stage IV Bladder Urothelial Carcinoma AJCC v7 | Stage II Bladder Urothelial Carcinoma AJCC v6 and v7 | Muscle Invasive Bladder Urothelial Carcinoma

United States
National Cancer Institute (NCI)

Completed

Temozolomide, Cixutumumab, and Combination Chemotherapy in Treating Patients With Metastatic Rhabdomyosarcoma

Stage IV Adult Soft Tissue Sarcoma | Adult Rhabdomyosarcoma | Metastatic Childhood Soft Tissue Sarcoma | Childhood Alveolar Rhabdomyosarcoma | Childhood Embryonal Rhabdomyosarcoma | Untreated Childhood Rhabdomyosarcoma

United States, Canada, Australia, New Zealand
Myovant Sciences GmbH

Completed

Study of Relugolix With Estradiol and Norethindrone Acetate in Women With Heavy Menstrual Bleeding Associated With Uterine Fibroids

Uterine Fibroids | Uterine Leiomyoma

United States, Italy, Poland, Czechia, Hungary, South Africa, Brazil, Chile

Clinical Trials on Muscle Spasticity in Ireland

Sponsors and Collaborators

Medical Conditions

Drug Interventions

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CROs in Bangladesh

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Drug Interventions

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Sponsor/Collaborators

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