Clinical Trials on Musculoskeletal Complications in Czechia

Total 859 results

AstraZeneca

Terminated

Randomised Double-Blind, Placebo-Controlled, Parallel Group Study in Patients With Active Rheumatoid Arthritis:Magnetic Resonance Imaging Sub-Study (OSKIRA 4 SS)

Rheumatoid Arthritis

United States, Bulgaria, Russian Federation, South Africa, United Kingdom, Germany, Hungary, Netherlands, Canada, Czech Republic, Poland
Novartis Pharmaceuticals

Completed

Long Term Study of Canakinumab (ACZ885) in Patients With Gout

Gouty Arthritis

Colombia, Spain, Taiwan, Russian Federation, Guatemala, Belgium, United States, Argentina, Czechia, Germany, Hungary, Poland, Portugal, Singapore, Slovakia, South Africa, Turkey, United Kingdom
Fibrex Medical Research & Development GmbH

Completed

Efficacy of FX06 in the Prevention of Myocardial Reperfusion Injury

Myocardial Infarction | Myocardial Ischemia | Coronary Disease

Austria, Belgium, Czech Republic, Denmark, Germany, Lithuania, Netherlands, Poland, Romania, Sweden, Switzerland
Sandoz

Completed

Comparative Efficacy and Safety Study of GP2015 and Enbrel® in Patients With Rheumatoid Arthritis (EQUIRA)

Rheumatoid Arthritis

Estonia, Italy, Lithuania, United Kingdom, United States, Bulgaria, Czechia, Poland, Slovakia, Spain, Latvia, Serbia, Hungary, Russian Federation, Mexico, Germany
Novartis Pharmaceuticals

Active, not recruiting

Gevokizumab With Standard of Care Anti-cancer Therapies for Metastatic Colorectal, Gastroesophageal, and Renal Cancers

Renal Cell Carcinoma | Colorectal Cancer | Gastroesophageal Cancer

United Kingdom, Australia, Belgium, Germany, Italy, Taiwan, Czechia, Israel, Spain, Japan, Singapore, Canada, Korea, Republic of, United States, Chile
SOTIO Biotech AG
SOTIO Biotech a.s.

Active, not recruiting

Study of SO-C101 and SO-C101 in Combination With Pembro in Adult Patients With Advanced/Metastatic Solid Tumors

Melanoma | Renal Cell Carcinoma | Cervical Cancer | Hepatocellular Carcinoma | Gastric Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Mesothelioma | Bladder Cancer | Triple Negative Breast Cancer | Small-cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Thyroid | Anal Cancer | Merkel Cell Carcinoma | Biliary... and other conditions

United States, France, Spain, Czechia
Janssen Research & Development, LLC

Completed

A Study of JNJ-40346527 in Patients With Active Rheumatoid Arthritis Despite Disease-modifying Antirheumatic Drug Therapy

Arthritis, Rheumatoid

Poland, Ukraine, Chile, Korea, Republic of, Singapore, Russian Federation, Argentina, Bulgaria, Hungary, Czech Republic
Biotest
AbbVie

Terminated

Study to Investigate the Safety and Efficacy of Tregalizumab in Subjects (MTX-IR) With Active Rheumatoid Arthritis (986)

Rheumatoid Arthritis

United States, Bulgaria, Canada, Czechia, Estonia, Germany, Hungary, Lithuania, Mexico, Poland, Russian Federation, Serbia, Slovakia, Ukraine
MedImmune LLC

Terminated

A Long Term Safety Study of Mavrilimumab in Adult Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

Bulgaria, Poland, Russian Federation, South Africa, Spain, United Kingdom, Estonia, Hungary, Ukraine, Argentina, Chile, Czechia, Israel, Slovakia, Greece, Germany, Serbia, Colombia, Mexico
Novartis Pharmaceuticals

Completed

24 Week Efficacy and 3-year Safety and Efficacy of Secukinumab in Active Psoriatic Arthritis

Psoriatic Arthritis

United Kingdom, Germany, Italy, Spain, United States, Australia, Bulgaria, Russian Federation, Czechia, Canada, Netherlands, Switzerland, Puerto Rico
Hoffmann-La Roche

Completed

A Study to Evaluate the Efficacy and Safety of Mabthera Alone and in Combination With Either Cyclophosphamide or Methotrexate in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

Belgium, Italy, Poland, Spain, Germany, United Kingdom, Canada, Israel, Australia, Netherlands, Czech Republic
Corbus Pharmaceuticals Inc.

Completed

Trial to Evaluate Efficacy and Safety of Lenabasum in Dermatomyositis (DETERMINE)

Dermatomyositis

United States, Korea, Republic of, Japan, Spain, United Kingdom, Germany, Hungary, Bulgaria, Canada, Czechia, Italy, Poland, Sweden
Novartis Pharmaceuticals

Completed

16-week Efficacy and 2-year Safety, Tolerability and Efficacy of Secukinumab in Participants With Active Ankylosing Spondylitis (MEASURE4)

Spondylitis, Ankylosing

Germany, Austria, Denmark, United States, Australia, Netherlands, Poland, Italy, Bulgaria, Spain, Russian Federation, United Kingdom, Greece, Czechia, Canada, Norway, Slovakia, Switzerland, Finland
NS Pharma, Inc.
Nippon Shinyaku Co., Ltd.

Active, not recruiting

Study to Assess the Safety and Efficacy of Viltolarsen in Ambulant Boys With DMD (RACER53-X)

Duchenne Muscular Dystrophy

Korea, Republic of, Chile, Japan, China, United Kingdom, Netherlands, Spain, Norway, Russian Federation, Australia, Greece, Italy, New Zealand, Turkey, Mexico, Czechia, Canada
UCB Biopharma SRL

Completed

A Study to Evaluate the Safe and Effective Use of the Prefilled Safety Syringe or the Auto-injector for the Subcutaneous Self-injection of Bimekizumab Solution by Subjects With Active Psoriatic Arthritis

Psoriatic Arthritis

United States, Czechia, Germany, Hungary, Poland, Russian Federation
Reneo Pharma Ltd

Completed

An Efficacy and Safety Study of 24 Week Treatment With Mavodelpar (REN001) in Primary Mitochondrial Myopathy Patients (STRIDE)

Primary Mitochondrial Myopathy

United States, Spain, Australia, France, United Kingdom, New Zealand, Denmark, Norway, Czechia, Belgium, Canada, Germany, Hungary, Italy, Netherlands
Eli Lilly and Company
Incyte Corporation

Completed

A Study in Participants With Rheumatoid Arthritis on Background Methotrexate Therapy

Arthritis, Rheumatoid

Hungary, Romania, United States, Czechia, Croatia, Poland, Ukraine, Mexico, India
Alentis Therapeutics AG

Recruiting

Rescue of Nephrons With ALE.F02 (RENAL-F02) (RENAL-F02)

Glomerulonephritis Rapidly Progressive

Czechia, Spain, Germany, Denmark, Italy, United Kingdom, France, Switzerland, Sweden, Turkey
argenx

Recruiting

A Study to Assess the Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Active Idiopathic Inflammatory Myopathy (ALKIVIA+)

Myositis | Dermatomyositis | Polymyositis | Antisynthetase Syndrome | Immune-Mediated Necrotizing Myopathy | Active Idiopathic Inflammatory Myopathy

Korea, Republic of, Thailand, United States, Bulgaria, Taiwan, Argentina, Belgium, Cyprus, Denmark, France, Georgia, Germany, Greece, Italy, Lithuania, Czechia, Sweden
UCB Pharma

Completed

Open Label Long-Term Safety Study of Certolizumab Pegol (CZP) for Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

United States, United Kingdom, Belgium, Germany, Austria, Ireland, Czechia
Archigen Biotech Limited

Completed

PK, PD, Safety, and Efficacy of SAIT101 Versus MabThera® Versus Rituxan® in Patients With Rheumatoid Arthritis

Rheumatoid Arthritis

United States, Korea, Republic of, Hungary, Poland, Czechia, Spain, Bosnia and Herzegovina, Bulgaria, Germany, India, Mexico
Ablynx

Completed

A Phase IIb Study for ALX-0061 Monotherapy in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

Czechia, Bulgaria, Germany, Mexico, Poland, Romania, Serbia, Spain, Hungary, United States, Belgium, Georgia, Moldova, Republic of, North Macedonia
Hoffmann-La Roche

Completed

A Study of Bonviva (Ibandronate) in Women With Post-Menopausal Osteoporosis Who Have Received Previous Bonviva Treatment

Post-Menopausal Osteoporosis

Spain, South Africa, Germany, Mexico, Italy, Belgium, United States, Poland, Denmark, Hungary, Czech Republic, France, Norway, United Kingdom, Australia
Italfarmaco

Completed

Phase II Study With ITF2984 in Acromegalic Patients (POC)

Acromegaly

France, Hungary, Netherlands, Serbia, Czech Republic, Italy, Spain, Poland, Romania
Fresenius Kabi SwissBioSim GmbH

Completed

MSB11456 in Participants With Moderately to Severely Active Rheumatoid Arthritis

Rheumatoid Arthritis

Hungary, Serbia, Georgia, Russian Federation, Slovakia, Czechia, Bulgaria, Moldova, Republic of, Poland
UCB Biopharma S.P.R.L.

Completed

A Study to Evaluate the Efficacy and Safety of Different Doses of Bimekizumab in Subjects With Active Ankylosing Spondylitis (BE AGILE)

Ankylosing Spondylitis

United States, Bulgaria, Canada, Czechia, Germany, Hungary, Poland, Russian Federation, Spain, Ukraine
Glenmark Pharmaceuticals Ltd. India
Glenmark Pharmaceuticals S.A.

Completed

A Clinical Trial to Study the Effects GRC 17536 in Patients With Painful Diabetic Peripheral Neuropathy (Painful Extremities Due to Peripheral Nerve Damage in Diabetic Patients).

Painful Diabetic Peripheral Neuropathy

India, Czech Republic, Germany, United Kingdom
Celgene

Terminated

A Study of CC-99677 in Participants With Active Ankylosing Spondylitis (AS SpA axSpA)

Spondylitis, Ankylosing

United States, China, Czechia, Germany, Poland, Romania, Spain, Turkey
VectivBio AG

Active, not recruiting

Open-label Extension Trial to Evaluate the Long-term Safety of Apraglutide in Short Bowel Syndrome. (STARS extend)

Short Bowel Syndrome

United States, Belgium, United Kingdom, Korea, Republic of, Japan, Taiwan, Germany, France, Czechia, Hungary, Spain, Italy, Poland, Argentina, Denmark, Israel, Norway, Sweden
Bayer

Completed

Non-proliferative Diabetic Retinopathy Treated With Runcaciguat (NEON-NPDR)

Diabetic Retinopathy

United States, Czechia, Denmark, Portugal, Spain, United Kingdom, Netherlands, Bulgaria, Latvia, Slovakia, Germany, Poland, Romania, Switzerland
Novartis Pharmaceuticals

Recruiting

A Multi-center Study to Evaluate the Safety, Tolerability and Efficacy of TIN816 in Patients at Risk for Acute Kidney Injury Following Cardiac Surgery.

Acute Kidney Injury Following Cardiac Surgery

France, Taiwan, Belgium, Germany, Argentina, Spain, Czechia, Hungary, Singapore, Estonia, Brazil, Lithuania
Janssen Research & Development, LLC

Completed

An Efficacy And Safety Study of CNTO 6785 In Participants With Active Rheumatoid Arthritis Despite Methotrexate Therapy

Rheumatoid Arthritis

Poland, Argentina, Colombia, Philippines, Russian Federation, Thailand, Czech Republic
Pfizer

Completed

Methotrexate Withdrawal Study of Tofacitinib Modified Release Formulation in Subjects With Rheumatoid Arthritis

Rheumatoid Arthritis

Korea, Republic of, United States, Poland, Bulgaria, Australia, Belgium, Hungary, Spain, United Kingdom, Czechia, Slovakia, Germany, Mexico, Philippines, Russian Federation, South Africa
Pfizer

Completed

An Efficacy And Safety Study Evaluating Tofacitinib With And Without Methotrexate Compared To Adalimumab With Methotrexate (ORAL STRATEGY)

Rhematoid Arthritis

Spain, United Kingdom, United States, Korea, Republic of, Poland, Israel, Australia, Taiwan, Thailand, South Africa, Bulgaria, Estonia, Latvia, Philippines, Canada, Romania, Russian Federation, Turkey, Mexico, Bosnia and Herzegovina and more
Pfizer's Upjohn has merged with Mylan to form Viatris...

Terminated

A Study To Evaluate Pregabalin In The Treatment Of Moderate To Severe Chronic Bone Pain Related To Metastatic Cancer (COPE)

Cancer | Bone Neoplasms | Pain, Intractable

Italy, Spain, United States, Canada, France, Hungary, Poland, Sweden, Taiwan, Korea, Republic of, Philippines, Peru, Venezuela, Finland, Czechia, Egypt, Mexico, Russian Federation, Thailand
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

Efficacy and Safety Study of Pregabalin in the Treatment of Pain on Walking in Patients With Diabetic Peripheral Neuropathy (DPN)

Diabetic Peripheral Neuropathy

United States, Czechia, Sweden, South Africa
AbbVie

Completed

A Study Investigating the Efficacy and Safety of Upadacitinib (ABT-494) Given With Methotrexate (MTX) in Adults With Rheumatoid Arthritis Who Have Had an Inadequate Response to MTX Alone

Rheumatoid Arthritis

United States, Bulgaria, Chile, Czechia, Hungary, Israel, Latvia, Mexico, Poland, Puerto Rico, Russian Federation, Slovakia, South Africa, Spain, Turkey, Ukraine
Sanofi
Regeneron Pharmaceuticals

Completed

To Evaluate The Safety of SAR153191 (REGN88) and Tocilizumab Added to Other RA Drugs in Patients With RA Who Are Not Responding to or Intolerant of Anti-TNF Therapy (SARIL-RA-ASCERTAIN)

Rheumatoid Arthritis

United States, Argentina, Belgium, Brazil, Czechia, Estonia, Finland, Hungary, Israel, Italy, Mexico, Netherlands, Poland, Romania, Russian Federation, Spain, Sweden, United Kingdom, Norway
Takeda
Nimbus Lakshmi, Inc.

Completed

A Study to Evaluate the Efficacy, Safety, and Tolerability of NDI-034858 in Participants With Active Psoriatic Arthritis

Psoriatic Arthritis

United States, Czechia, Germany, Poland
Johnson & Johnson Pharmaceutical Research & Development...

Terminated

An Efficacy and Safety Study of JNJ-38518168 in Adult Participants With Rheumatoid Arthritis

Rheumatoid Arthritis

Poland, United Kingdom, Taiwan, Spain, Korea, Republic of, Belgium, Russian Federation, Czech Republic, Netherlands, Ireland
Vertex Pharmaceuticals Incorporated

Completed

Phase 2 Clinical Study in Rheumatoid Arthritis With an Investigational Oral p38 MAP Kinase Inhibitor VX-702

Rheumatoid Arthritis

Poland, Croatia, Russian Federation, Bulgaria, Czech Republic, Former Serbia and Montenegro, Slovakia, Slovenia, Ukraine
Pfizer
Hospira, now a wholly owned subsidiary of Pfizer

Completed

Post-Marketing Use Of CT-P13 (Infliximab) For Standard Of Care Treatment Of Rheumatoid Diseases Who Are Naïve To Biologics Or Switched From Remicade (PERSIST)

Rheumatoid Arthritis | Psoriatic Arthritis | Ankylosing Spondylitis | Rheumatoid Diseases

Spain, Canada, Greece, United Kingdom, Germany, Bulgaria, Czechia
Ipsen

Completed

Dysport® Adult Lower Limb Spasticity Study

Leg Spasticity

United States, Australia, France, Belgium, Czechia, Hungary, Italy, Poland, Portugal, Russian Federation, Slovakia
Merck Sharp & Dohme LLC

Completed

Golimumab (MK-8259 / SCH900259) Treatment Withdrawal in Participants With Non-radiographic Axial Spondyloarthritis (GO-BACK) (MK-8259-038)

Spondyloarthritis

Czechia, Germany, Netherlands, Poland, Romania, Russian Federation, Spain, Turkey, Ukraine
Lexicon Pharmaceuticals

Completed

Study of LX3305 in Subjects With Active Rheumatoid Arthritis on Stable Methotrexate

Rheumatoid Arthritis

United States, Bulgaria, Czech Republic, Hungary, Poland, Serbia
Hoffmann-La Roche

Completed

MOBILE Study - A Study of Bonviva (Ibandronate) Regimens in Women With Post-Menopausal Osteoporosis

Post Menopausal Osteoporosis

Australia, United Kingdom, United States, Brazil, Germany, South Africa, France, Spain, Switzerland, Italy, Canada, Hungary, Belgium, Mexico, Poland, Denmark, Norway, Czechia, Romania
Fujifilm Kyowa Kirin Biologics Co., Ltd.

Completed

A Study to Compare FKB327 Long-term Safety, Efficacy and Immunogenicity With Humira® in Rheumatoid Arthritis Patients (ARABESC-OLE)

Arthritis, Rheumatoid

Poland, Russian Federation, United States, Germany, Romania, Ukraine, Canada, Chile, Czechia, Spain, Peru
ReveraGen BioPharma, Inc.
University of Pittsburgh; Newcastle University; European Union; Cooperative International...

Completed

A Study to Assess the Efficacy and Safety of Vamorolone in Boys With Duchenne Muscular Dystrophy (DMD)

Duchenne Muscular Dystrophy

United States, Belgium, Canada, United Kingdom, Spain, Netherlands, Sweden, Czechia, Australia, Greece, Israel
Amgen

Completed

A Study Evaluating the Efficacy and Safety of ABP 959 Compared With Eculizumab in Adult Participants With PNH (DAHLIA)

Paroxysmal Nocturnal Hemoglobinuria

Spain, Italy, United States, Norway, Czechia, United Kingdom, Slovenia, Netherlands, Turkey, Portugal, Finland, France, Ireland, Sweden
Eli Lilly and Company
Rigel Pharmaceuticals

Recruiting

An Adaptive Phase 2a/2b Study of LY3871801 in Adult Participants With Rheumatoid Arthritis

Rheumatoid Arthritis

United States, France, United Kingdom, Argentina, Mexico, India, Czechia, Germany, Slovakia

Clinical Trials on Musculoskeletal Complications in Czechia

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