Clinical Trials on Neurocognitive Impairment in Belgium

Total 194 results

Universitaire Ziekenhuizen KU Leuven
CHDI Foundation, Inc.

Completed

Dosimetry of [11C]CHDI-180R and [11C]CHDI-626.

Huntington Disease

Belgium
University of Liege

Completed

Multichannel tDCS to Reduce Hypertonia in Patients With Prolonged DOC

Disorder of Consciousness | Spasticity, Muscle | Minimally Conscious State | Vegetative State

Belgium
University of Liege
Centre Hospitalier Neurologique William Lennox (Belgium); Hôpital Valdor -... and other collaborators

Recruiting

Apomorphine in Severe Brain-injured Patients (APODoC)

Disorder of Consciousness

Belgium, Spain
Janssen Research & Development, LLC

Completed

Characterization of T-Cell Response in Participants Previously Treated With JNJ-54861911 (Atabecestat)

Alzheimer Disease

France, Belgium, Germany, Spain, Sweden
Universitaire Ziekenhuizen KU Leuven

Recruiting

In Vivo PET of Synaptic Density in Cognitive Disorders

Alzheimer Disease | Frontotemporal Degeneration | Psychiatric Disorder | Dementia With Lewy Bodies

Belgium
University of Liege

Completed

Use of Analgesic Treatment to Reduce Signs of Pain in Patients With Disorders of Consciousness.

Disorders of Consciousness | Minimally Conscious State | Severe Brain Injury | Post-comatose Non-communicative Patients | Vegetative State

Belgium
Centre Hospitalier Universitaire Saint Pierre
Fonds iris-Recherche, Fondation Roi Baudouin, Belgium

Completed

Evaluation of the Role of OCT in the Detection of HIV-associated Neurocognitive Disorder (OCT-HIV)

AIDS-Related Dementia Complex

Belgium
Universitaire Ziekenhuizen KU Leuven
Research Foundation Flanders

Recruiting

Connectivity and Neural Signatures of Consciousness in Unresponsive States (CONSCIUS)

Seizures | Traumatic Brain Injury | Consciousness Disorders | Acute Brain Injury

Belgium
Janssen Research & Development, LLC

Completed

A Study to Investigate Safety and Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-63733657 in Healthy Subjects and Subjects With Alzheimer's Disease

Alzheimer Disease

Belgium, Spain, Netherlands, Germany
University Hospital of Mont-Godinne
Université Catholique de Louvain; Teva Pharmaceuticals USA

Terminated

Improving Cognitive Aptitudes With tDCS in Patients With Multiple Sclerosis (MScog-tDCS)

Relapsing Remitting Multiple Sclerosis | Motor Deficits | Cognitive Deficits | Secondary-progressive Multiple Sclerosis

Belgium
Universitaire Ziekenhuizen KU Leuven

Completed

Synaptic Density and Progression of Huntington's Disease.

Huntington Disease

Belgium
Cliniques universitaires Saint-Luc- Université...

Recruiting

Early UVFP Management Based on Neurological Evidences (ION-UVFP) - Preliminary Study

Unilateral Vocal Cord Paralysis | Central Auditory Processing Disorder

Belgium
Kyowa Kirin Co., Ltd.
Kyowa Hakko Kirin Pharma, Inc.

Completed

A Study of Single and Multiple Doses of KHK6640 in Subjects With Prodromal or Mild to Moderate Alzheimer's Disease

Alzheimer's Disease

Belgium, Finland, Netherlands, Serbia, Sweden
KU Leuven
Odisee University college for applied sciences

Not yet recruiting

Anxiety, Stress and Sleep Problems in People With Early Onset Dementia (Young-D)

Stress | Insomnia | Sleep | Anxiety | Distress, Emotional | Sleep Problem | Early Onset Dementia | Young Onset Dementia

Belgium
Fondazione Don Carlo Gnocchi Onlus
University of Liege; Ludwig-Maximilians - University of Munich; University Hospital... and other collaborators

Not yet recruiting

Spontaneous Eye Blinking in Disorders of Consciousness (Blink-DoC)

Disorders of Consciousness

Germany, Belgium, Italy, Spain
University of Liege

Recruiting

Transcutaneous Auricular Vagal Nerve Stimulation for Post-coma Patients With Disorders of Consciousness

Minimally Conscious State | Vegetative State | Consciousness Disorder

Belgium
Géraldine Martens
Centre Hospitalier Universitaire Dinant Godinne - UCL Namur

Completed

Long Term Effects of Soft Splints on Stroke Patients and Patients With Disorders of Consciousness

Pathologic Processes | Stroke | Central Nervous System Diseases | Neurocognitive Disorders | Brain Injuries | Craniocerebral Trauma | Trauma, Nervous System | Disorder of Consciousness | Contracture | Spasticity as Sequela of Stroke | Hypertonic Disorder

Belgium
Novartis

Completed

A 12 Month Core Study to Assess the Efficacy and Safety of Ranibizumab (Intravitreal Injections) in Patients With Visual Impairment Due to Diabetic Macular Edema and a 24 Month Open-label Extension Study (RESTORE)

Diabetic Macular Edema

Greece, Belgium, Spain, France, Netherlands, Australia, Canada, Germany, Hungary, Italy, Switzerland, Turkey, United Kingdom
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Effects of JNJ-54861911 on Amyloid Beta Processing in Cerebrospinal Fluid and Plasma in Patients With Prodromal Alzheimer's Disease

Alzheimer Disease

Spain, Netherlands, Belgium, Sweden
Fondazione Europea di Ricerca Biomedica Ferb Onlus
Mediolanum Cardio Research

Unknown

REspectful CAring for the AGitated Elderly (RECAGE)

Dementia

Germany, Belgium, France, Greece, Italy, Norway, Switzerland
University of Lausanne Hospitals
Université Catholique de Louvain; Mindmaze SA; Centre de Recherche de l'Institut... and other collaborators

Completed

The StayFitLonger Study: an Innovative Computerized Home-based Training to Foster Independent Life at Home (SFL)

Cognitive Decline Prevention in Robust Older Adults | Cognitive Decline Prevention in Pre-frail Older Adults | Physical Decline Prevention in Robust Older Adults | Physical Decline Prevention in Pre-frail Older Adults

Belgium, Canada, Switzerland
prof. dr. Koen Van Laere
Universitaire Ziekenhuizen KU Leuven; KU Leuven; University Hospital, Ghent; Fund...

Not yet recruiting

[18F]-MFBG Versus [123I]-MIBG and [18F]-PE2I in PD vs. MSA and DBL vs. AD

Parkinson Disease | Alzheimer Disease | Dementia With Lewy Bodies | MSA - Multiple System Atrophy

Belgium
Raman Health Technologies, S.L.

Completed

Multi-parameter Diagnostic Blood Test for the Diagnosis of Alzheimer's Disease (RH-VAL)

Alzheimer Disease

Spain, Belgium, France
Tel-Aviv Sourasky Medical Center
KU Leuven; Newcastle University; Universita degli Studi di Genova; University Medical...

Completed

A Treadmill Training Program Augmented by Virtual Reality to Decrease Fall Risk in Older Adults (VTIME)

Parkinson | Mild Cognitive Disorder | Elderly Adults

Israel, Belgium, Italy, Netherlands, United Kingdom
Janssen Research & Development, LLC

Terminated

An Extension Study to Evaluate the Long-Term Safety and Tolerability of JNJ-54861911 in Participants in the Early Alzheimer's Disease Spectrum

Alzheimer Disease

France, Spain, Netherlands, Belgium, Germany, Sweden
Novartis Pharmaceuticals

Completed

Dose-ranging Safety and Tolerability Study in Subjects ≥60 Years of Age

Alzheimer's Disease

Netherlands, United States, Belgium, Germany, United Kingdom
Air Liquide Santé International
OptumInsight

Completed

Hip Fracture Surgery in Elderly Patients (HIPELD)

Delirium

Spain, Belgium, France, Germany, United Kingdom, Italy
Janssen Research & Development, LLC

Completed

A Safety and Tolerability Study of JNJ-54861911 in Participants With Early Alzheimer's Disease

Alzheimer's Disease

France, Spain, Netherlands, Belgium, Germany, Sweden
University of Liege
Centre Hospitalier Universitaire de Nīmes; Centre Hospitalier Universitaire... and other collaborators

Recruiting

Development and Validation of the SWADOC Tool

Dysphagia | Swallowing Disorders | Disorders of Consciousness | Speech Therapy | Assessment Tool

France, Belgium
Vivoryon Therapeutics N.V.
Amsterdam UMC, location VUmc; Julius Clinical

Completed

Safety and Tolerability of PQ912 in Subjects With Early Alzheimer's Disease (SAPHIR)

Alzheimer's Disease

Spain, Finland, Germany, Netherlands, Belgium, France, Sweden
Noscira SA
ICON Clinical Research

Completed

Efficacy, Safety and Tolerability of Tideglusib to Treat Mild-to-Moderate Alzheimer's Disease Patients (ARGO)

Alzheimer's Disease

Belgium, Finland, France, Germany, Spain, United Kingdom
Hoffmann-La Roche

Terminated

A Study to Evaluate the Pharmacodynamic (PD) Effects of Once Weekly Administration of Gantenerumab in Participants With Early Alzheimer's Disease (AD)

Alzheimer Disease

Belgium, United States, Poland, Spain, Germany, Italy, France, United Kingdom
Novartis Pharmaceuticals

Completed

Safety, Tolerability and Abeta-specific Antibody Response of Repeated i.m. Injections of Adjuvanted CAD106 in Mild Alzheimer Patients

Alzheimer's Disease

Belgium, Switzerland, Spain, United States, Italy, Sweden, Canada, Germany, Norway, Netherlands
University of Edinburgh
Innovative Medicines Initiative

Terminated

European Prevention of Alzheimer's Dementia (EPAD) Longitudinal Cohort Study (LCS) (EPAD-LCS)

Alzheimer's Dementia

United Kingdom, Belgium, France, Greece, Italy, Netherlands, Spain, Sweden, Switzerland
Prevail Therapeutics
Eli Lilly and Company

Recruiting

Phase 1/2 Clinical Trial of LY3884963 in Patients With Frontotemporal Dementia With Progranulin Mutations (FTD-GRN) (PROCLAIM)

Frontotemporal Dementia

United States, Australia, Belgium, Spain, United Kingdom, France
Novartis Pharmaceuticals

Completed

A Study of the Efficacy and Safety of Brolucizumab vs. Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema (KITE)

Diabetic Macular Edema

Czechia, India, Russian Federation, Taiwan, Turkey, Lebanon, Denmark, Estonia, France, Germany, Hungary, Korea, Republic of, Latvia, Lithuania, Bulgaria, Norway, Belgium, Malaysia, Sweden, Slovakia, Singapore, Poland, Switzerland
Bellus Health Inc

Unknown

European Study of 3APS in Mild to Moderate Alzheimer's Disease Patients

Alzheimer's Disease

Poland, France, Spain, Switzerland, Netherlands, Italy, Germany, Sweden, United Kingdom, Belgium
Boehringer Ingelheim

Completed

Alzheimer Disease Proof of Concept Study With BI 409306 Versus Placebo

Alzheimer Disease

United States, Spain, Canada, United Kingdom, Germany, Italy, Netherlands, Portugal, Austria, Belgium, France, Poland
Pfizer

Completed

Multiple IV Dose Study Of PF-04360365 In Patients With Mild To Moderate Alzheimer's Disease

Alzheimer's Disease

Korea, Republic of, Canada, United States, Australia, United Kingdom, Belgium
FORUM Pharmaceuticals Inc

Unknown

Study to Assess the Safety, Tolerability, and Pharmacodynamic (PD) Effects of FRM-0334 in Subjects With Prodromal to Moderate Frontotemporal Dementia With Granulin Mutation

Granulin Mutation

Belgium, United States, France, Italy, Netherlands, United Kingdom
Amoneta Diagnostics SAS
Assistance Publique - Hôpitaux de Paris; University Hospital, Geneva; University... and other collaborators

Unknown

ADDIA Proof-of-Performance Clinical Study (ADDIA)

Frontotemporal Lobar Degeneration | Progressive Supranuclear Palsy (PSP) | Dementia With Lewy Bodies (DLB) | Corticobasal Degeneration (CBD) | Alzheimer Disease (AD) | Parkinson Disease Dementia (PDD)

Belgium, France, Italy, Switzerland, Turkey
Pfizer

Terminated

A Long-Term Safety And Tolerability Study Of Bapineuzumab In Alzheimer Disease Patients

Alzheimer Disease

Australia, France, Finland, Portugal, Spain, United Kingdom, Poland, Japan, Italy, Belgium, Switzerland, Netherlands, Chile, Slovakia, Sweden, New Zealand, South Africa
AstraZeneca

Completed

Proof of Concept Study of Cognitive Improvement in Patients With Alzheimer's Disease (Sirocco)

Alzheimer Disease

Bulgaria, Czech Republic, Russian Federation, United Kingdom, Germany, Romania, Canada, Austria, Belgium, Spain
GlaxoSmithKline

Completed

A Study of the Efficacy and Safety of Albiglutide in Subjects With Type 2 Diabetes With Renal Impairment.

Diabetes Mellitus, Type 2

United States, Germany, Peru, Israel, Taiwan, Australia, Russian Federation, United Kingdom, Korea, Republic of, Spain, Brazil, Colombia, India, Philippines, South Africa
AbbVie

Terminated

An Extension Study of ABBV-8E12 in Early Alzheimer's Disease (AD)

Alzheimer's Disease

United States, Australia, Belgium, Canada, Denmark, Finland, Italy, New Zealand, Spain, Sweden
TauRx Therapeutics Ltd

Completed

Safety and Efficacy of TRx0237 in Subjects With Alzheimer's Disease Followed by Open-Label Treatment

Alzheimer Disease

United States, Spain, Poland, Belgium, France, United Kingdom, Italy, Canada
UCB Biopharma SRL

Active, not recruiting

A Study to Test the Efficacy, Safety, and Tolerability of Bepranemab (UCB0107) in Patients With Mild Cognitive Impairment or Mild Alzheimer's Disease (AD)

Alzheimer's Disease

United States, Belgium, Canada, France, Germany, Italy, Netherlands, Poland, Spain, United Kingdom
FORUM Pharmaceuticals Inc
Syneos Health

Completed

A 26-Week Extension Study of EVP-6124 (Alpha-7 nAChR) as an Adjunctive Pro-Cognitive Treatment in Schizophrenia Subjects on Chronic Stable Atypical Antipsychotic Therapy

Schizophrenia | Impaired Cognition

United States, Ukraine, United Kingdom, Germany, Spain, Argentina, Canada, Singapore, Russian Federation, Italy, Mexico, Colombia, Australia, Belgium, Poland, Romania
TauRx Therapeutics Ltd

Completed

Safety and Efficacy Study Evaluating TRx0237 in Subjects With Mild Alzheimer's Disease

Alzheimer's Disease

United States, Spain, Canada, Belgium, France, Italy, Croatia, Finland, Germany, United Kingdom, Australia, Netherlands
Myrexis Inc.

Terminated

Global Efficacy Study of MPC-7869 to Treat Patients With Alzheimer's

Dementia | Alzheimer Disease

France, United States, Belgium, Germany, Spain, Canada, Netherlands, Italy, Denmark, Switzerland, Sweden, United Kingdom

Clinical Trials on Neurocognitive Impairment in Belgium

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