Clinical Trials on Neuromuscular Disease in United Kingdom

Total 147616 results

Idera Pharmaceuticals, Inc.

Completed

Trial of IMO-8400 in Adult Patients With Dermatomyositis (8400-211)

Dermatomyositis

United States, Hungary, United Kingdom
Case Comprehensive Cancer Center

Withdrawn

Clinical Trial of Acupuncture for Chemotherapy-Induced Peripheral Neuropathy

Peripheral Neuropathy

United States
Johns Hopkins University

Terminated

Effect of Transcranial Direct Current Stimulation on Peripheral Neuropathy

Peripheral Neuropathy

United States
Legacy Health System

Completed

Treatment Trial Using Low Level Laser Therapy (LLLT) for Treatment of Chemotherapy Induced Peripheral Neuropathy (LLL)

Peripheral Neuropathy

United States
Columbia University
National Institute of Neurological Disorders and Stroke (NINDS); National Institute...

Recruiting

Measuring Physical Activity With ActivPal (Activpal)

Neuromuscular Diseases

United States
National Institute of Neurological Disorders and...

Completed

Rituximab to Treat Neuropathy With Anti-MAG Antibodies

Polyneuropathies

United States
Shenandoah University

Completed

Effects of Light Emitting Diode Irradiation on the Conduction Parameters of the Superficial Radial Nerve

Peripheral Neuropathy

United States
University of Edinburgh
University College, London; NHS Lothian; University of Warwick

Recruiting

Motor Neurone Disease - Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART)

Motor Neuron Disease, Amyotrophic Lateral Sclerosis

United Kingdom
Biogen

Completed

A Study for Participants With Spinal Muscular Atrophy (SMA) Who Previously Participated in Nusinersen (ISIS 396443) Investigational Studies (SHINE)

Spinal Muscular Atrophy

United States, Spain, Germany, United Kingdom, Australia, Japan, Canada, Belgium, France, Hong Kong, Italy, Korea, Republic of, Sweden, Turkey
Laboratoire français de Fractionnement et de Biotechnologies
TFS Trial Form Support

Completed

LIME Study (LFB IVIg MMN Efficacy Study) (LIME)

Motor Neuron Disease

Spain, United Kingdom, Italy, France
Indiana University

Completed

Evaluation of an Exercise Intervention for Vincristine Induced Peripheral Neuropathy in Pediatric Cancer Patients (Exercise)

Peripheral Neuropathy

United States
Brigham Young University
Sorenson Legacy Foundation; Brigham Young University MRI Research Facility

Completed

Central Mechanisms of Calmare: an fMRI Trial

Peripheral Neuropathy

United States
George Mason University

Completed

Effects of Reiki, Yoga, Meditation, on the Physical and Psychological Symptoms of Chemotherapy-Induced Peripheral Neuropathy

Peripheral Neuropathy

United States
Alexion Pharmaceuticals

Completed

Extension Study of ECU-MG-301 to Evaluate Safety and Efficacy of Eculizumab in Refractory Generalized Myasthenia Gravis

Refractory Generalized Myasthenia Gravis

Italy, United Kingdom, Spain, Belgium, Turkey, Japan, United States, Netherlands, Korea, Republic of, Argentina, Hungary, Sweden, Denmark, Brazil, Czechia, Finland, Canada
DAS-MG, Inc

Recruiting

Study of Pyridostigmine With Ondansetron in Subjects With Anti-AchR Positive Myasthenia Gravis

Myasthenia Gravis

United States
Power Life Sciences Inc.

Not yet recruiting

Examining Engagement Trends Among Participants in Peripheral Neuropathy Clinical Research

Peripheral Neuropathy

United States
University of Rochester

Completed

Exercise and Nutrition Interventions During Chemotherapy

Neuropathy;Peripheral

United States
Mannkind Corporation

Completed

A Study Designed to Determine if the Drugs Albuterol (Salbutamol) and Fluticasone Have an Effect on the Pharmacokinetics of the Investigational Product Technosphere® Insulin Inhalation Powder in Healthy Volunteers

Diabetes Mellitus | Healthy Subjects

United Kingdom
Merz Pharmaceuticals GmbH

Completed

IncobotulinumtoxinA (Xeomin) for Upper Limb Spasticity (NT-Spin)

Upper Limb Spasticity

France, Spain, Switzerland, United Kingdom, Italy, Austria, Germany, Portugal
ProgenaBiome

Recruiting

A Pilot Study to Explore the Role of Gut Flora in Myasthenia Gravis

Myasthenia Gravis | Myasthenia Gravis, Generalized

United States
Alexion Pharmaceuticals

Withdrawn

Study of ALXN1830 Administered Subcutaneously in Adults With Generalized Myasthenia Gravis

Generalized Myasthenia Gravis

United States
Biogen

Recruiting

A Study of Spinraza (Nusinersen) Exposure in Pregnant Women With Spinal Muscular Atrophy (SMA) Within Existing SMA Registries

Muscular Atrophy, Spinal

United States
Indiana University School of Medicine
Cure SMA

Completed

International SMA Patient Registry

Muscular Atrophy, Spinal

United States
Humanitas Mirasole SpA
KU Leuven; UMC Utrecht; University of Sheffield; Istituto Superiore di Sanità; University... and other collaborators

Recruiting

Open Label Extension of TUDCA-ALS Study (TUDCA-ALS OLE)

Amyotrophic Lateral Sclerosis

Germany, France, Netherlands, Italy, United Kingdom, Belgium, Ireland
Dartmouth-Hitchcock Medical Center

Completed

Exercise and Oxaliplatin-induced Peripheral Neuropathy

Peripheral Neuropathy

United States
Washington University School of Medicine
Orthopedic Research and Education Foundation

Terminated

Thromboelastography Transfusion Protocol for Pediatric Neuromuscular Scoliosis Surgery

Neuromuscular Scoliosis

United States
Abbott Nutrition

Completed

Evaluation of an Oral Nutritional Supplement Containing AN777

Malnutrition | Sarcopenia

Spain, United States, Italy, Poland, Belgium, Mexico, Switzerland, United Kingdom
Virginia Commonwealth University
Washington University School of Medicine; University of Iowa; University of Minnesota and other collaborators

Recruiting

Defining Clinical Endpoints in Limb Girdle Muscular Dystrophy (LGMD) (GRASP-01-001)

Muscular Dystrophies | Limb Girdle Muscular Dystrophy

United States, United Kingdom
Cabaletta Bio

Recruiting

RESET-MG: A Study to Evaluate the Safety and Efficacy of CABA-201 in Participants With Generalized Myasthenia Gravis

Generalized Myasthenia Gravis (gMG)

United States
Prisma Health-Upstate

Completed

Evaluating the Effects of Acupuncture in the Treatment of Taxane Induces Peripheral Neuropathy

Peripheral Neuropathy

United States
William Beaumont Hospitals
Camber Spine Technologies

Terminated

Prospective Study of Fusion Rates Using Spira-C Device for Anterior Cervical Discectomy and Fusion Surgery (ACDF)

Cervical Radiculopathy | Cervical Disc Disease

United States
Icahn School of Medicine at Mount Sinai

Terminated

Erector Spinae Block for Spine Surgery

Lumbar Radiculopathy

United States
Johns Hopkins University

Terminated

Post-lesion Administration of Dexamethasone to Prevent the Development of Neuritis After Radiofrequency Ablation

Neuritis | Radiofrequency Ablation

United States
Rocky Mountain University of Health Professions

Unknown

Manual Therapy, Exercise and Traction for Patients With Cervical Radiculopathy: A RCT

Cervical Radiculopathy

United States
Boston Medical Center
National Institute on Aging (NIA)

Terminated

TOM: Testosterone in Older Men With Sarcopenia

Muscular Diseases | Sarcopenia | Hypogonadism

United States
Merck Sharp & Dohme LLC

Completed

Efficacy, Safety, and Pharmacokinetics of Sugammadex (MK-8616) for Reversal of Neuromuscular Blockade in Pediatric Participants Aged Birth to <2 Years (MK-8616-169)

Neuromuscular Blockade

United States, Australia, Belgium, Brazil, Denmark, Finland, France, Guatemala, Hungary, Malaysia, Mexico, Netherlands, Peru, Russian Federation
argenx

Active, not recruiting

A Clinical Trial to Investigate the Safety and Tolerability, Efficacy, Pharmacokinetics, Pharmacodynamics and Immunogenicity of 2 Dose Regimens of ARGX-117 in Adults With Multifocal Motor Neuropathy (ARDA)

Multifocal Motor Neuropathy

United States, France, Germany, Belgium, Italy, Netherlands, Canada, United Kingdom, Austria, Poland, Spain
Texas Tech University Health Sciences Center

Recruiting

Annatto-derived GG for Statin-associated Myopathy (GG-statin)

Myopathy; Primary

United States
National University of Natural Medicine

Recruiting

MORE in the Management of Lumbosacral Radiculopathy Symptoms: A Randomized Controlled Trial (MORE)

Lumbar Radiculopathy

United States
Momenta Pharmaceuticals, Inc.

Completed

A Study to Evaluate the Safety, Tolerability, Efficacy, Pharmacokinetics and Pharmacodynamics of M281 Administered to Adults With Generalized Myasthenia Gravis

Generalized Myasthenia Gravis

United States, Belgium, Canada, Germany, Italy, Poland, Spain, United Kingdom
Biohaven Pharmaceuticals, Inc.

Active, not recruiting

A Study to Evaluate the Efficacy and Safety of Taldefgrobep Alfa in Participants With Spinal Muscular Atrophy (RESILIENT)

Neuromuscular Diseases | Spinal Muscular Atrophy | SMA

United States, Netherlands, United Kingdom, Spain, Czechia, Belgium, Germany, Italy, Poland
Stealth BioTherapeutics Inc.

Terminated

A Trial to Evaluate Safety and Efficacy of Elamipretide Primary Mitochondrial Myopathy Followed by Open-Label Extension (MMPOWER-3)

Primary Mitochondrial Myopathy

United States, Germany, Canada, Italy, United Kingdom, Denmark, Hungary
Brigham and Women's Hospital

Recruiting

Detection of Small Fiber Neuropathy Using Skin Properties

Small Fiber Neuropathy

United States
Johns Hopkins University
Adelson Medical Research Foundation

Completed

Evaluation of Nicotinamide Riboside in Prevention of Small Fiber Axon Degeneration and Promotion of Nerve Regeneration

Small Fiber Neuropathy

United States
University of Missouri-Columbia

Completed

Dispersal Pattern for Spine Injections (Gadolinium Contrast)

Cervical Radiculopathy

United States
EMD Serono Research & Development Institute, Inc.
Merck KGaA, Darmstadt, Germany

Recruiting

Study of M5049 in DM and PM Participants (NEPTUNIA)

Dermatomyositis | Polymyositis

United States, Italy, Spain, Greece, Czechia, United Kingdom, Poland
Novartis Pharmaceuticals

Completed

Real-World Use of Novel Treatments in Patients With Spinal Muscular Atrophy (SMA): A Multi-Site Retrospective Chart Review of Pediatric SMA Patients Outside of the United States

Spinal Muscular Atrophy

United States
NYU Langone Health
Winthrop University Hospital

Withdrawn

Pulmonary Function Test Changes and Respiratory Muscle Strength Trends in Spinal Muscular Atrophy Patients Receiving Nusinersen Treatments

Spinal Muscular Atrophy

United States
Hoffmann-La Roche

Completed

A Drug-drug Interaction Study With Risdiplam Multiple Dose and Midazolam in Healthy Participants

Spinal Muscular Atrophy

United States
National Institute of Neurological Disorders and...

Completed

Measuring Levels of SMN in Blood Samples of SMA Patients

Spinal Muscular Atrophy

United States

Clinical Trials on Neuromuscular Disease in United Kingdom

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