Clinical Trials on Neurotoxicity Syndromes in United Kingdom

Total 14183 results

Columbia University

Completed

Glutamine in Treating Neuropathy Caused by Vincristine in Young Patients With Lymphoma, Leukemia, or Solid Tumors

Sarcoma | Lymphoma | Kidney Cancer | Leukemia | Neurotoxicity | Peripheral Neuropathy

United States
Genethon

Active, not recruiting

Long Term Safety Follow up of Haematopoietic Stem Cell Gene Therapy for the Wiskott Aldrich Syndrome (WASFUP)

Wiskott-Aldrich Syndrome

United Kingdom, France
ResMed
Imperial College London; Royal Brompton & Harefield NHS Foundation Trust

Completed

Mechanisms of Action of Adaptive Servoventilation

Heart Failure | Sleep Apnea Syndromes

United Kingdom
Gilead Sciences
California Institute for Regenerative Medicine (CIRM)

Completed

CAMELLIA: Anti-CD47 Antibody Therapy in Haematological Malignancies

Acute Myeloid Leukemia | Myelodysplastic Syndrome

United Kingdom
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Neurobehavioral Complications in Children Who Were Previously Treated With Steroids and Intrathecal Therapy for Acute Lymphoblastic Leukemia

Leukemia | Neurotoxicity | Long-term Effects Secondary to Cancer Therapy in Children | Psychosocial Effects of Cancer and Its Treatment

United States
Prof. Janet Dunn
King's College Hospital NHS Trust; University of Manchester; University of Birmingham and other collaborators

Recruiting

Repurposed Drugs to Improve Haematological Responses in Myelodysplastic Syndromes (REPAIR-MDS)

Myelodysplastic Syndromes (MDS)

United Kingdom
Kyowa Kirin, Inc.

Terminated

Study of KHK2823 in Patients With Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)

Acute Myeloid Leukemia | Myelodysplastic Syndrome

United Kingdom
University of Nottingham
Medical Research Council; National Institute for Health Research, United Kingdom

Recruiting

Characterising Frailty Using Magnetic Resonance Imaging (PHENOFRIM)

Frail Elderly Syndrome | Frailty | Frailty Syndrome

United Kingdom
National Institute of Allergy and Infectious Diseases...

Completed

A Study to Evaluate the Effects of Giving IL-2 Alone to HIV-Positive Patients With CD4 Cell Counts of at Least 350 Cells/mm3 Who Do Not Wish to Receive Anti-HIV Therapy

HIV Infections

United Kingdom
GlaxoSmithKline

Withdrawn

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Proof of Mechanism of GSK2618960 in Primary Sjögren's Syndrome (pSS)

Autoimmune Diseases

United Kingdom
Cell Medica Ltd
University College, London; Cell Therapy Catapult

Completed

A Phase I/II Study of Gene-modified WT1 TCR Therapy in MDS & AML Patients

Myelodysplastic Syndromes (MDS) | Acute Myeloid Leukaemia (AML)

United Kingdom, Germany, Belgium
The Whiteley Clinic
Bauerfeind

Recruiting

Study to Investigate the Influence of Compression Treatment in Patients With Pelvic Congestion Syndrome (PCS)

Pelvic Congestive Syndrome

United Kingdom
Gilead Sciences

Completed

SWEET: Once Daily Truvada Versus Twice Daily Combivir for the Treatment of HIV Infection

HIV Infections

United Kingdom
Radboud University Medical Center

Recruiting

A Prospective, Multicentre European Registry for Newly Diagnosed Patients With Myelodysplastic Syndromes (EUMDS)

Myelodysplastic Syndromes (MDS)

Denmark, Switzerland, Serbia, Austria, Croatia, Czechia, France, Germany, Greece, Israel, Italy, Netherlands, Poland, Portugal, Romania, Spain, Sweden, United Kingdom
Premaitha Health

Completed

Clinical Evaluation of the IONA Test for Non-invasive Pre Natal Screening in Twin Pregnancies (TWIN)

Down Syndrome | Patau Syndrome | Edward's Syndrome

United Kingdom
Blackpool Teaching Hospitals NHS Foundation Trust

Not yet recruiting

Subacromial Injections for Shoulder Subacromial Pain Syndrome - Anterolateral vs Posterior Approach

Shoulder Subacromial Pain Syndrome

United Kingdom
Cardiff and Vale University Health Board
South East Wales Trials Unit (SEWTU); Tenovus

Completed

Low Anterior Resection Syndrome and Rectal Irrigation Study (LARRIS)

Anterior Resection Syndrome

United Kingdom
University of South Florida
National Cancer Institute (NCI); Children's Oncology Group

Completed

Glutamic Acid in Reducing Nerve Damage Caused by Vincristine in Young Patients With Cancer

Sarcoma | Lymphoma | Kidney Cancer | Leukemia | Neurotoxicity | Peripheral Neuropathy

United States
PENTA Foundation

Completed

Pharmacokinetic (PK) Study of Twice Daily vs Once Daily Lamivudine (3TC) and Abacavir (ABC) as Part of Combination Antiretroviral Therapy (ART) in HIV Infected Children (PENTA 13)

HIV Infection

United Kingdom
Chelsea and Westminster NHS Foundation Trust
Merck Sharp & Dohme LLC; Imperial College London; University of Liverpool

Completed

Pharmacokinetics of Plasma Doravirine Once Daily Over 72 Hours Following Drug Intake Cessation in Healthy Volunteers

Human Immunodeficiency Virus

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
Veryan Medical Ltd.

Recruiting

Structured Exercise Versus Endovascular Reconstruction in Post Thrombotic Syndrome (SEvERe-PTS)

Post Thrombotic Syndrome

United Kingdom
King's College Hospital NHS Trust
Alexandra Hospital, Athens, Greece

Completed

RCT of Laser Therapy for GSM

Genitourinary Syndrome of Menopause

United Kingdom
Jazz Pharmaceuticals

Completed

A Dose-ranging Pharmacokinetics and Safety Study of GWP42003-P in Children With Dravet Syndrome (GWPCARE1)

Epilepsy | Dravet Syndrome

United States, United Kingdom
Mirati Therapeutics Inc.

Terminated

Phase 2 Study of Azacitidine (Vidaza) vs MGCD0103 vs Combination in Elderly Subjects With Newly Diagnosed Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)

Acute Myeloid Leukemia (AML) | Myelodysplastic Syndrome (MDS)

United States, Canada, United Kingdom
St. Bartholomew's Hospital

Unknown

Early Diagnosis of Aspergillosis in Patients at High Risk of Fungal Infection Caused by Treatment for Hematologic Cancer or Other Disease

Myelodysplastic Syndromes | Leukemia | Infection | Graft Versus Host Disease | Myelodysplastic/Myeloproliferative Neoplasms

United Kingdom
University of Edinburgh
NHS Lothian

Completed

BLB Study Back or Leg Pain and Bladder Symptoms Study (BLB)

Cauda Equina Syndrome | Functional Neurological Disorder

United Kingdom
Royal Devon and Exeter NHS Foundation Trust

Completed

Singing Exercises to Improve Symptoms of Snoring and Sleep Apnea

Snoring | Obstructive Sleep Apnea | Upper Airway Resistance Syndrome

United Kingdom
NHS Greater Glasgow and Clyde
NHS Research Scotland

Recruiting

Clinical Characteristics and Subgroups in Greater Trochanteric Pain Syndrome

Greater Trochanteric Pain Syndrome

United Kingdom
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Brain Function in Young Patients Receiving Methotrexate for Acute Lymphoblastic Leukemia

Untreated Childhood Acute Lymphoblastic Leukemia | Childhood T Acute Lymphoblastic Leukemia | Neurotoxicity Syndrome | Childhood B Acute Lymphoblastic Leukemia | Cognitive Side Effects of Cancer Therapy | Psychological Impact of Cancer | Long-Term Effects Secondary to Cancer Therapy in Children

United States, Canada, Australia, New Zealand
Northumbria University
Newcastle University; Versus Arthritis; Teesside University

Unknown

Pilot Feasibility Study of a Sjögren's Syndrome Self-management App

Sjogren's Syndrome

United Kingdom
Indiana University

Completed

Switch From Calcineurin Inhibitor to Belatacept in Pancreas Transplant Recipients

Nephrotoxicity

United States
Shire

Completed

Long-term Study of Teduglutide in Pediatric Subjects With Short Bowel Syndrome Who Completed the TED-C13-003 Study

Short Bowel Syndrome

United States, United Kingdom
Cardiff University
Experimental Cancer Medicine Centres; Leukaemia & Lymphoma Research Group

Completed

A Trial to Establish the Feasibility of Combining Either the Tyrosine Kinase Inhibitor AC220,CXCR4 Inhibitor Plerixafor or HSP90 Inhibitor Ganetespib With Chemotherapy in Older Patients With Acute Myeloid Leukaemia and High Risk Myelodysplastic Syndrome. (AML18 Pilot)

High Risk Myelodysplastic Syndrome | Acute Myeloid Leukaemia

United Kingdom
Womb Transplant UK
Oxford University Hospitals NHS Trust; Imperial College Healthcare NHS Trust

Recruiting

INvestigational Study Into Transplantation of the Uterus (INSITU)

Cervical Cancer | Postpartum Hemorrhage | Mayer-Rokitansky-Kuster Syndrome | Asherson's Syndrome

United Kingdom
Imperial College London

Completed

Clinical Trial of HIV Vaccine Combinations in Healthy Men and Women (Ad4HIV)

Human Immunodeficiency Virus

United Kingdom
University of Oxford
Wellcome Trust

Recruiting

Mechanisms of Neurodynamic Treatments (MONET)

Carpal Tunnel Syndrome | Physiotherapy | Neurodynamic Treatment | Nerve Mobilisation | Diffusion MRI | Mechanistic Trial

United Kingdom
GlaxoSmithKline
Quintiles, Inc.

Completed

A PH I Pilot Imaging Study to Evaluate Molecular Imaging Methods in HVs and pSS Pts

Autoimmune Diseases

United Kingdom
Resolve Therapeutics
Newcastle-upon-Tyne Hospitals NHS Trust; University Hospital Birmingham

Completed

A Study of RSLV-132 in Subjects With Primary Sjogren's Syndrome (RSLV-132)

Sjogren's Syndrome

United Kingdom
University Hospitals Coventry and Warwickshire...
National Institute for Health Research, United Kingdom

Completed

TMJ Dysfunction Following Use of SAD

Temporomandibular Joint Disorder Bilateral

United Kingdom
Shire

Completed

Safety, Efficacy and Pharmacokinetic Study of Teduglutide in Infants 4 to 12 Months of Age With Short Bowel Syndrome

Short Bowel Syndrome

Finland, Italy, United Kingdom, France
Cardiff and Vale University Health Board
Cambridge University Hospitals NHS Foundation Trust; University of Aarhus; University...

Completed

Translation of the International Consensus Definition of LARS Into a Bowl Dysfunction Severity Scoring Tool (New LARS Score)

Low Anterior Resection Syndrome

United Kingdom
Imperial College London

Completed

Service Development: Assessing Non-attendance Rates in Outpatient Clinics

Sleep Apnea Syndromes | Asthma | Tuberculosis | COPD

United Kingdom
ViiV Healthcare
GlaxoSmithKline

Completed

Bioavailability of BMS-626529 in Healthy Subjects From Prototype Low Dose Extended Release Formulations (Part 1) and Prototype Extended Release Multi-particulate Formulations (Part 2) of BMS-663068 Relative to 600 mg Extended Release Tablet

Infection, Human Immunodeficiency Virus

United Kingdom
ViiV Healthcare
GlaxoSmithKline

Completed

Relative Bioavailability Study With BMS-955176

Infection, Human Immunodeficiency Virus

United Kingdom
University of Central Lancashire

Recruiting

Impact of 'SESL01' Lens on Computer Vision Syndrome

Computer Vision Syndrome

United Kingdom
Croydon University Hospital

Completed

Obstructed Defaecation: Proctography Versus Ultrasound in Symptomatic Patients (OPUS)

Obstructed Defaecation Syndrome

United Kingdom
ViiV Healthcare
GlaxoSmithKline

Completed

Absolute Bioavailability of BMS-626529 After Oral and Intravenous Dosing

Infection, Human Immunodeficiency Virus

United Kingdom
St Stephens Aids Trust

Completed

PK of Tenofovir, Emtricitabine and Efavirenz in Healthy Volunteers

HIV Infections | HIV Infection

United Kingdom
University of Oxford

Terminated

Safety and Immunogenicity of a Candidate MERS-CoV Vaccine (MERS001)

MERS (Middle East Respiratory Syndrome)

United Kingdom
Chelsea and Westminster NHS Foundation Trust
Gilead Sciences; Imperial College London

Terminated

Efficacy, Tolerability and Acceptability of Biktarvy by TPLWH

Human Immunodeficiency Virus

United Kingdom

Clinical Trials on Neurotoxicity Syndromes in United Kingdom

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