Clinical Trials on Nicotine

Total 499 results

Philip Morris Products S.A.

Completed

Reduced HPHC Exposure in Cigarette Smokers Switching to P4M3 Gen. 2.0 Compared to Continuing Smoking, or Smoking Abstinence

Nicotine | Nicotine Vaping | Vaping

United Kingdom
Philip Morris Products S.A.

Completed

Nicotine Pharmacokinetics Following Use of the P4M3 Gen 2.0 E-Cigarette Compared to Smoking Cigarettes

Nicotine | Nicotine Vaping | Vaping

United States
Virginia Commonwealth University
National Institute on Drug Abuse (NIDA)

Completed

The Effect of Electronic Cigarette (ECIG) Liquid Vehicles on ECIG Acute Effects

Nicotine Exposure | Nicotine Withdrawal Suppression

United States
Fred Hutchinson Cancer Center
National Institute on Drug Abuse (NIDA)

Active, not recruiting

A Smartphone Application (ACT on Vaping) for Vaping Cessation in Young Adults

Nicotine Dependence | Nicotine Use Disorder | Nicotine Vaping | Vaping | Nicotine Addiction

United States
Yale University

Completed

The Effect of Nicotine Delivery Rate on Reinforcement

Nicotine

United States
Ohio State University Comprehensive Cancer Center

Recruiting

Developing E-liquid Product Standards (Sweet Spot Study)

Nicotine | Nicotine Vaping | E-cigarette Use

United States
Philip Morris Products S.A.

Completed

Nicotine Pharmacokinetics and Subjective Effects of Nicotine Pouch 1.0 Compared to Velo® Ice Cool and Zyn® Cool Mint Mini Dry in Healthy Smokers

Smoking | Nicotine

United Kingdom
The University of Texas Health Science Center,...
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Completed

Thirdhand Smoke Contamination in a Neonatal Intensive Care Unit (NICU)

Nicotine Exposure

United States
Queen Mary University of London

Completed

Sensorimotor Replacement With Electronic and De-nicotinised Cigarettes (SenRep)

Nicotine Withdrawal

United Kingdom
Yale University
American University of Beirut Medical Center

Recruiting

Nicotine Flux, a Potentially Powerful Tool for Regulating Nicotine Delivery From Electronic Cigarettes

Nicotine Vaping

United States
American University of Beirut Medical Center
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Recruiting

Assess the Influence of Nicotine Flux and Nicotine Form on Subjective Effects Related to Dependency

Nicotine Dependence | Nicotine Vaping | Nicotine Addiction

Lebanon
Philip Morris Products S.A.

Completed

Study to Investigate the Nicotine Pharmacokinetic Profiles and Pharmacodynamic Effects of P4M3 Variants

Vaping | Nicotine Absorption

United States
Simbec Research
CN creative

Completed

A Study of Blood Levels of Nicotine Following an Electronic Cigarette

Nicotine Replacement Therapy
Pharmaceutical Productions Inc.
National Institute on Drug Abuse (NIDA)

Completed

Pilot Pharmacokinetic Study of Investigational Sublingual Nicotine Tablet Versus COMMIT Nicotine Lozenge

Nicotine Pharmacokinetic Study

United States
Milton S. Hershey Medical Center
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH); Food and Drug Administration (FDA)

Completed

Switching to Low Oxidant Content Cigarettes in Adult Smokers

Oxidative Stress | Nicotine

United States
Maastricht University Medical Center
Maastricht University

Completed

A Fmri Study on the Effects of a Conjugate Vaccine and Placebo on CNS Activation and Behavior Following a Nicotine Challenge (EPU057)

Smoking | Nicotine Dependency

Netherlands
Yale University
National Institute on Drug Abuse (NIDA)

Enrolling by invitation

Impact of Flavors on Nicotine Perception and Self-Administration Via E-cigarettes

Nicotine | E-liquid Flavors

United States
University of California, Irvine
National Institute on Drug Abuse (NIDA)

Completed

Association Between Smoking, Brain Activity, Genes, and ADHD

Smoking | ADHD | Withdrawal Nicotine

United States
National Institute of Respiratory Diseases, Mexico

Recruiting

Effectiveness of Combined Tobacco Treatment in Hospitalized Subjects

Tobacco Smoking | Nicotine Addiction | Nicotine Withdrawal | Nicotine Replacement Therapy | Tobacco Withdrawal

Mexico
Virginia Polytechnic Institute and State University
Medical University of South Carolina

Recruiting

Promotion and Mitigation Factors Leading to Illegal Tobacco Purchases

Cigarette Smoking | Nicotine Vaping

United States
Yale University
National Institute on Drug Abuse (NIDA)

Completed

Water Content in E-Liquids

Nicotine E-Cigarette Use

United States
Virginia Polytechnic Institute and State University
Medical University of South Carolina; National Cancer Institute (NCI)

Completed

Comparison of the Substitution Between Different Tobacco/Nicotine Products as a Function of Tobacco-user Type

Cigarette Smoking | Nicotine Vaping

United States
Cedars-Sinai Medical Center

Terminated

Effects of Nicotine-Free Hookah Smoking on Blood Flow to the Heart, Muscle and Skin

Nicotine-free Hookah Smoking

United States
Milton S. Hershey Medical Center

Completed

The Get Quit - Stay Quit Study (GQSQ)

Nicotine Dependent Cigarette Smoker

United States
University of California, San Francisco
National Institute on Drug Abuse (NIDA); National Institutes of Health (NIH)

Withdrawn

Cigarette Harm Reduction With Electronic Cigarette Use (NIDA-SREC)

Cardiovascular Risk Factor | Nicotine Dependence | Nicotine Dependence, Cigarettes | Nicotine Withdrawal | Tobacco Toxicity

United States
Virginia Commonwealth University
National Institute on Drug Abuse (NIDA)

Recruiting

Potential Effects of Electronic Nicotine Delivery System Flavor Regulations on African American Menthol Smokers (RVA Flavors)

Electronic Nicotine Delivery System Flavors

United States
University of Nottingham

Completed

Experiences of Pregnant Women Who Use NRT in Pregnancy as Part of a Quit Attempt

Pregnancy | Nicotine Replacement Therapy | Qualitative

United Kingdom
Ottawa Heart Institute Research Corporation
Canadian Institutes of Health Research (CIHR)

Active, not recruiting

The INITIATE Study: Initiating Nicotine Dependence Treatment for Smokers Admitted to Emergency Departments (INITIATE)

Nicotine Dependence, Cigarettes | Nicotine Withdrawal

Canada
Peking University
China Medical Board

Not yet recruiting

Effects of Dress by Adolescents on Electronic Cigarette Retailer Behaviors in China

Regulation Compliance | Electronic Nicotine Delivery Systems
University of Maryland, Baltimore
National Institute on Drug Abuse (NIDA)

Completed

Nicotinic Modulation of the Default Network

Magnetic Resonance Imaging | Cognition | Nicotine | Mecamylamine

United States
Washington University School of Medicine
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Helping Poor Smokers Quit

Smoking | Smoking Cessation | Tobacco Use | Tobacco Smoking | Tobacco Use Cessation | Nicotine Dependence | Tobacco Dependence | Smoking, Tobacco | Nicotine Use Disorder | Nicotine Dependence, Cigarettes | Smoking, Cigarette | Nicotine Dependence Tobacco Product | Tobacco; Use, Rehabilitation | Smoking (Tobacco) Addiction and other conditions

United States
University of California, San Francisco
National Institute on Drug Abuse (NIDA)

Not yet recruiting

Comparative Pharmacokinetics and Pharmacodynamics of Synthetic Nicotine

Nicotine Dependence | Nicotine Vaping

United States
University of Pennsylvania
National Institute on Drug Abuse (NIDA)

Completed

Progesterone and Brain Imaging Study

Nicotine Dependence | Nicotine Withdrawal

United States
University of Pennsylvania

Completed

Nicotine and Brain Imaging Research Study

Nicotine

United States
University of Oslo
Charles University, Czech Republic; The Research Council of Norway

Recruiting

Negotiating a Quit Date or Not in Online Interventions

Nicotine Dependence, Cigarettes

Czechia, Norway
Medical University of South Carolina

Completed

Translational Neuropsychopharmacology Research of Nicotine Addiction

Nicotine Dependence, Cigarettes

United States
Medical University of South Carolina
National Institute on Drug Abuse (NIDA)

Completed

Combined Pharmaco/Behavior Therapy in Adolescent Smokers

Nicotine Dependence | Nicotine Use Disorder

United States
Duke University
National Institutes of Health (NIH); National Center for Advancing Translational... and other collaborators

Terminated

Self-activation in Individuals With and Without Nicotine Dependence

Addiction Nicotine

United States
Yale University
National Institute on Drug Abuse (NIDA); US Department of Veterans Affairs

Completed

Treatment for Nicotine Addiction in Women

Nicotine Dependence

United States
National Institute on Drug Abuse (NIDA)
University of Maryland

Completed

Pilot Study of Transcranial Magnetic Stimulation (TMS) in Nicotine Addiction

Nicotine Dependence

United States
University of Minnesota
National Institute on Drug Abuse (NIDA); Pfizer

Completed

Human Laboratory Study of Varenicline and Bupropion for Nicotine Dependence (ChanBan)

Nicotine Dependence | Nicotine Withdrawal

United States
National Institute on Drug Abuse (NIDA)

Completed

Studying Nicotine Addiction With Transcranial Magnetic Stimulation

Nicotine Dependence

United States
University of Oslo
Charles University, Czech Republic; The Research Council of Norway

Recruiting

Comparing SMS and E-mail Reminders in an Online Smoking Cessation Intervention

Nicotine Dependence Tobacco Product

Norway, Czechia
National Defense Medical Center, Taiwan

Recruiting

Effects of HRV Biofeedback on Autonomic Function and Nicotine Withdrawal Symptoms and Dependence in Smoking Cessation Adults

Heart Rate Variability, Biofeedback, Nicotine Dependence, Nicotine Withdrawal, Anxiety, Depression, Insomnia

Taiwan
Washington University School of Medicine
National Institute on Drug Abuse (NIDA); The University of Texas Health Science... and other collaborators

Not yet recruiting

Testing the Feasibility and Acceptability of Social Media and Digital Therapeutics to Decrease Vaping Behaviors

Nicotine Use Disorder | Nicotine Vaping
University of Chicago

Withdrawn

Nicotine Virtual Reality Conditioned Place Preference (NEVE)

Nicotine Use Disorder | Nicotine Addiction

United States
University of Vermont
National Institute on Drug Abuse (NIDA)

Completed

Impact of Nicotine Messaging on Nicotine Beliefs and Tobacco Use Behavior

Nicotine Dependence, Cigarettes

United States
Freedom Laser, Inc.
NST Consultants, Inc.

Completed

Evaluation of LLLT/Music for Smoking Cessation

Nicotine Dependence, Cigarettes

United States
University of Vermont
National Institute of General Medical Sciences (NIGMS)

Completed

Improving Smoking Cessation in Socioeconomically-Disadvantaged Young Adults

Nicotine Dependence, Cigarettes

United States
Medical University of South Carolina

Terminated

Accelerated rTMS for the Reduction of Nicotine Craving

Nicotine Dependence | Nicotine Use Disorder

United States

Clinical Trials on Nicotine

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CROs in South Korea

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