Clinical Trials on Niemann-Pick Disease Type A

Total 58688 results

University Hospital, Strasbourg, France

Recruiting

Direct Diagnosis of Disseminated Lyme Borreliosis. (DIALYD)

Lyme Disease

France
National Institute of Allergy and Infectious Diseases...

Recruiting

Evaluation, Treatment, and Follow-up of Patients With Lyme Disease

Lyme Disease

United States
Pfizer
Valneva Austria GmbH

Active, not recruiting

An Efficacy, Safety, Tolerability, Immunogenicity, and Lot-Consistency Clinical Trial of a 6-Valent OspA-Based Lyme Disease Vaccine (VLA15) (VALOR)

Lyme Disease

United States, Finland, Canada, Poland, Sweden, Germany, Netherlands
ModernaTX, Inc.

Active, not recruiting

A Study to Evaluate the Safety and Immunogenicity of mRNA-1975 and mRNA-1982 Against Lyme Disease in Participants 18 Through 70 Years of Age

Lyme Disease

United States
MassBiologics
Celerion

Completed

First Clinical Study of the Safety and Blood Levels of a Human Monoclonal Antibody (2217LS) Against Lyme Disease Bacteria in Healthy People

Lyme Disease

United States
T2 Biosystems

Terminated

Detection of Borrelia Bacteria in Early Stage Lyme Borreliosis Using the T2Lyme Panel

Lyme Disease

United States
Brigham and Women's Hospital
Centers for Disease Control and Prevention

Completed

A School-Based Intervention to Reduce Lyme Disease

Lyme Disease
Oxford Immunotec

Terminated

Lyme Test Indication Combinations (LyTIC) Study (LyTIC)

Lyme Disease

United States
Novartis Vaccines

Completed

Observational Study of Safety of Flu Cell Culture Derived Adjuvanted Swine Origin A (H1N1) Pandemic Subunit Vaccine

Novel Influenza A (H1N1) | A New Flu Virus of Swine Origin

Chile, Colombia, Germany, Switzerland
Aarhus University Hospital
Odense University Hospital; Zealand University Hospital; Rigshospitalet, Denmark and other collaborators

Completed

Reducing Atrial Pacing Rate to Reduce Atrial Fibrillation in Patients With Sick Sinus Syndrome. (DANPACEII)

Atrial Fibrillation | Sinus Node Disease

Denmark
JOTEC GmbH

Recruiting

Post-market Registry of the AMDS for the Treatment of Acute DeBakey Type I Dissection (PROTECT)

Aortic Dissection | Intramural Hematoma | Acute DeBakey I Dissection | Acute Type A Dissection

Germany
Medtronic BRC
Vitatron GmbH

Unknown

Mode Evaluation in Sick Sinus Syndrome Trial (MODEST)

Sick Sinus Syndrome

Germany
China Medical University Hospital

Unknown

The Role of Angiotensinogen Gene Polymorphism in the Pathogenesis of Non-familial Sick Sinus Syndrome

Sick Sinus Syndrome

Taiwan
The DANPACE Investigator Group

Terminated

The Danish Multicenter Randomised Study on AAI Versus DDD Pacing in Sick Sinus Syndrome

Sick Sinus Syndrome

Denmark
Rambam Health Care Campus

Unknown

The Optimal Timing for Cerclage Removal

Respiratory Disease of A Newborn

Israel
Hoffmann-La Roche

Active, not recruiting

A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Subcutaneous Emicizumab in Participants From Birth to 12 Months of Age With Hemophilia A Without Inhibitors (HAVEN 7)

Severe Hemophilia A

Canada, United States, United Kingdom, Belgium, Australia, Austria, Brazil, France, Germany, Israel, Italy, South Africa, Spain, Turkey
University of Wisconsin, Madison
National Institute on Deafness and Other Communication Disorders (NIDCD)

Enrolling by invitation

Vitamin A Status in Patients With Vocal Fold Leukoplakia

Vitamin A Deficiency | Leukoplakia | Vitamin A | Vocal Cord Neoplasm

United States
Enzyre B.V.
Instytut Hematologii i Transfuzjologii, Warschau, Poland

Completed

Real-life Clinical FEIBA Samples Measured Using the Version A of the HemA EnzySystem

Hemophilia A | Hemophilia A With Inhibitor

Poland
Swedish Orphan Biovitrum
Cerner Enviza

Completed

rFVIIIFc (Elocta®) ITI Chart Review in Patients With Haemophilia A

Hemophilia A With Inhibitor

France, Ireland, Italy, Norway, Germany, Kuwait, Saudi Arabia, Switzerland
BioMarin Pharmaceutical

Active, not recruiting

Gene Therapy Study in Severe Haemophilia A Patients (270-201)

Severe Haemophilia A

United Kingdom
AryoGen Pharmed Co.

Completed

rFVIII-Fc (Produced by AryoGen Pharmed Co.) Pharmacokinetic Study

Severe Hemophilia A

Iran, Islamic Republic of
Bayer

Completed

Study Evaluating "Real World" Treatment Pattern in Previously Treated Hemophilia A Patients Receiving KOVALTRY (Octocog Alfa) for Routine Prophylaxis (TAURUS)

Hemophilia A, Congenital

Slovenia, Italy, Germany, France, United States, Belgium, Canada, Colombia, Greece, Luxembourg, Netherlands, Spain, Taiwan
Margaret Ragni
Health Resources and Services Administration (HRSA)

Terminated

The Hemophilia Inhibitor Prevention Trial

Hemophilia A Without Inhibitor

United States
Grifols Biologicals, LLC

Completed

Safety Study of Alphanate in Previously Treated Patients With Severe Hemophilia A

Severe Hemophilia A

Poland
Bioverativ, a Sanofi company
Swedish Orphan Biovitrum

Completed

A Study to Evaluate Efficacy of rFVIIIFc for Immune Tolerance Induction (ITI) in Severe Hemophilia A Participants With Inhibitors Undergoing the First ITI Treatment (verITI-8 Study)

Hemophilia A With Inhibitors

United States, Spain, Canada, Belgium, France, Bulgaria, Italy, United Kingdom, Japan, Germany
Grifols Therapeutics LLC
Grifols Biologicals, LLC

Terminated

Alphanate in Immune Tolerance Induction Therapy

Hemophilia A, Congenital

United States, Spain, Italy, India, Canada, Russian Federation
Pfizer

Completed

PF-06741086 Long-term Treatment in Severe Hemophilia

Hemophilia A or B

Poland, Switzerland, South Africa, United States, Croatia, Brazil, Chile
Octapharma

Completed

Human Cell Line-derived Recombinant Factor VIII (Human-cl-rhFVIII) in Previously Untreated Patients

Severe Hemophilia A

Canada, United States, France, Spain, Ukraine, United Kingdom, Belarus, Georgia, Germany, India, Italy, Moldova, Republic of, Morocco, Poland, Portugal, Russian Federation, Slovenia
Octapharma

Completed

Clinical Study to Investigate the PK, Efficacy, and Safety of Wilate in Patients With Severe Hemophilia A

Severe Hemophilia A

Bulgaria, Poland, Hungary, Romania, Russian Federation
Bioverativ Therapeutics Inc.

Completed

Study of Recombinant Factor VIII Fc Fusion Protein (rFVIIIFc) in Subjects With Severe Hemophilia A

Severe Hemophilia A

United States, Hong Kong, Israel
Octapharma

Completed

Assess the Safety and Efficacy of Individually Tailored Prophylaxis With Human-cl rhFVIII in Patients With Severe Haemophilia A

Severe Haemophilia A

Austria, United Kingdom, Bulgaria, Hungary, Germany, Poland, Romania, Slovakia
Children's Hospital Los Angeles

Withdrawn

Individualizing Hemophilia Bypassing Agent Therapy Utilizing Thromboelastography

Hemophilia A With Inhibitors
University of Pittsburgh
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Hemophilia Adult Prophylaxis Study: Factor VIII in Severe Hemophilia A

Severe Hemophilia A

United States
Nara Medical University
Shire

Unknown

Basic Study of Combination Therapy Based on APCC-induced FVllI Activation in Hemophilia A Patients With Inhibitors

Hemophilia A With Inhibitor

Japan
Skane University Hospital

Completed

Hemophilia Inhibitor Genetics Study (HIGS)

Hemophilia A With Inhibitor

Sweden
New York Presbyterian Hospital
Manchester University NHS Foundation Trust

Terminated

International Immune Tolerance Study

Hemophilia A With Inhibitors

United States
Molde University College
Norwegian Labour and Welfare Administration

Completed

Obesity, Lifestyle and Work Intervention

Obesity | Morbid Obesity | Work Related Illnesses | Life Style | Sick-leave
Biotronik SE & Co. KG

Completed

Ventricular Pace Suppression Versus Intrinsic Rhythm Support Study (VIPERS)

Sick Sinus Syndrome

Italy
Abbott Medical Devices

Completed

HBP Device EGM Data Collection

Heart Failure | Sick Sinus Syndrome | AV Block

United States
Abbott Medical Devices

Terminated

Impact of Septal Vs Apical Pacing on Right and Left Ventricular Performance

Heart Block | Ventricular Dysfunction | Atrioventricular Block | Sick Sinus Syndrome

Switzerland
Boston Scientific Corporation

Completed

Safety and Performance Study of the INGEVITY Lead

Bradycardia | Sinus Node Dysfunction

United States, Belgium, Germany, Canada, Spain, Sweden, Italy, Malaysia, Denmark, Australia, Austria, United Kingdom, Hong Kong, France, Portugal, Thailand
Lars Rombo

Completed

Hepatitis A Vaccine in Patients With Immunomodulating Drugs

Response to Hepatitis A Vaccine

Finland, Sweden
Ospedale Santa Maria di Loreto Mare

Unknown

Right Ventricular Lead Placement in a Pacemaker Population: Evaluation of Apical and Alternative Position

Heart Block | Bradycardia | Sick Sinus Syndrome

Italy
Assistance Publique Hopitaux De Marseille

Unknown

Does Chemotherapy Train the Mutation of the Pig-A Gene? (PIGA)

Breast Cancer Female

France
Jiangsu Gensciences lnc.

Not yet recruiting

Study of Efficacy and Safety of FRSW107 in Pediatric Patients With Severe Hemophilia A

Severe Hemophilia A

China
Ascension Healthcare Development Limited

Recruiting

A Pharmacokinetic and Clotting Activity Study of FVIII-PEGLip

Hemophilia A With Inhibitor

Russian Federation
Swedish Orphan Biovitrum
Syneos Health

Active, not recruiting

A Study Evaluating Physical Activity and Joint Health in Severe Haemophilia A Patients ≥12 Years Treated Once Weekly With Efanesoctocog Alfa (FREEDOM)

Hemophilia A, Severe

Germany, Spain, France, Czechia, Netherlands, Ireland, Austria, Croatia, Greece, Italy, Norway, Slovenia, Sweden, United Kingdom
Novo Nordisk A/S

Completed

A Research Study of How a New Medicine NNC0365-3769 (Mim8) Works in the Body of Healthy People

Healthy Volunteers - Haemophilia A

Germany
Jiangsu Gensciences lnc.

Completed

A Study to Evaluate the Pharmacokinetics，Safety and Tolerability of PEG Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection

Severe Hemophilia A

China
Jiangsu Gensciences lnc.

Completed

A Study of Repeat Dosing of PEG Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection

Severe Hemophilia A

China

Clinical Trials on Niemann-Pick Disease Type A

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