Clinical Trials on Non-Cirrhotic Portal Hypertension in Germany

Total 45 results

University Hospital, Bonn

Recruiting

Predicting Acute-on-Chronic Liver Failure After Surgical Intervention in Chronic Liver Disease (PERSEVERE)

Liver Cirrhosis | Acute-On-Chronic Liver Failure | Surgery | Portal Hypertension | Non-Cirrhotic Portal Hypertension

Germany
University Hospital Freiburg

Recruiting

Freiburg TIPS Registry (FRETIR)

Liver Cirrhosis | Portal Hypertension | Portal Vein Thrombosis | Non-Cirrhotic Portal Hypertension | Budd Chiari Syndrome | Portal Systemic Shunt

Germany
University Hospital Freiburg

Recruiting

Prediction of Portal Hypertension in Patients With CVID (CVID-pHT) (CVID-pHT)

Common Variable Immunodeficiency | Non-Cirrhotic Portal Hypertension

Germany
University Hospital, Bonn

Completed

Myocardial Fibrosis and Inflammation in Liver Cirrhosis

Cardiomyopathies | Portal Hypertension | Cirrhosis, Liver

Germany
Histogen

Completed

Emricasan, an Oral Caspase Inhibitor, in Subjects With NASH Cirrhosis and Severe Portal Hypertension (ENCORE-PH)

Cirrhosis | Portal Hypertension | Non-alcoholic Steatohepatitis

United States, Germany, Spain
University Hospital, Bonn

Completed

Viatorr CX Case-control Study for Complications of Portal Hypertension (VIATORR-CX)

Portal Hypertension | Liver Cirrhoses

Germany
Johann Wolfgang Goethe University Hospital

Recruiting

Characterization and Pathogenesis of ACLF (ACLF-I)

Liver Cirrhosis | Acute-On-Chronic Liver Failure | Portal Hypertension

Germany
University Hospital, Bonn

Completed

Non-invasive Evaluation Program for TIPS and Follow Up Network (NEPTUN)

Portal Hypertension

Germany
University Hospital, Bonn

Recruiting

Non-invasive Evaluation Program for TIPS and Follow Up Network 2 (NEPTUN2) (NEPTUN2)

Portal Hypertension

Germany
Hannover Medical School

Recruiting

Improvement of Portal Hypertension During Viral Suppression in Patients With Hepatitis Delta (IMPHROVE-D) (IMPHROVE-D)

Liver Cirrhosis | Hepatitis B | Hepatitis D | Portal Hypertension

Germany
Boehringer Ingelheim

Terminated

A Study to Test Whether Avenciguat Helps People With Liver Cirrhosis and High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver) Who Had Bleeding in the Esophagus or Fluid Accumulation in the Belly

Liver Cirrhosis | Hypertension, Portal

Spain, Germany, Canada, China, Austria, United States, Japan, France, Korea, Republic of, Romania
University Hospital, Bonn

Recruiting

Multiparametric Cardio-hepatic MRI in Patients With Noncirrhotic Portal Hypertension

Cardiomyopathies | Hypertension, Portal

Germany
University of Ulm

Unknown

Spleen-ARFI-assisted-Portal-Hypertension-Evaluation-Study (SAPHES) (SAPHES)

Hypertension, Portal

Germany
Galectin Therapeutics Inc.

Active, not recruiting

Study Evaluating the Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in NASH Cirrhosis (NAVIGATE)

Cirrhosis | NASH - Nonalcoholic Steatohepatitis | Prevention of Esophageal Varices

United States, France, Spain, Australia, Canada, Israel, Puerto Rico, Belgium, Argentina, Chile, Germany, Korea, Republic of, Mexico, Poland, United Kingdom
University Hospital of Cologne

Unknown

24-h-ambulatory Blood Pressure Monitoring and Pulse Wave Analysis in NAFLD Patients (HyperNAFLD)

NAFLD; Hypertension, White-coat Hypertension, Masked Hypertension

Germany
Integra LifeSciences Corporation
Avania

Completed

CERTAS Programmable Valve Registry (CERTAS)

Hydrocephalus | NPH (Normal Pressure Hydrocephalus) | IIH - Idiopathic Intracranial Hypertension

Germany, Netherlands
Boehringer Ingelheim

Terminated

A Study to Test Whether Two Different Doses of Avenciguat Help People With Liver Cirrhosis and High Blood Pressure in the Portal Vein (Main Vessel Going to the Live

Hypertension, Portal

Spain, Denmark, United Kingdom, Singapore, Germany, Italy, Austria, Taiwan, Canada, Croatia, China, Netherlands, Belgium, United States, Japan, Argentina, France, Switzerland, Portugal, Israel, Romania, Korea, Republic of
SciPharm SàRL

Completed

Efficacy and Tolerability of Subcutaneously Administered Treprostinil Sodium in Patients With Severe (Non-operable) Chronic Thromboembolic Pulmonary Hypertension (CTREPH) (CTREPH)

Non-operable Chronic Thromboembolic Pulmonary Hypertension

Austria, Poland, Czechia, Germany
Integra LifeSciences Corporation

Recruiting

Post Market Clinical Follow-up of CODMAN CERTAS Programmable Valve

Brain Tumor | Hemorrhagic Stroke | Hydrocephalus | Hydrocephalus in Children | NPH (Normal Pressure Hydrocephalus) | IIH - Idiopathic Intracranial Hypertension | Post-Traumatic Hydrocephalus

Germany, Belgium
Hannover Medical School

Withdrawn

Cardiopulmonary Interactions in Patients With Heart Failure

Heart Failure | Pulmonary Hypertension | Heart Failure With Reduced Ejection Fraction | Heart Failure With Normal Ejection Fraction

Germany
Boehringer Ingelheim

Terminated

A Study to Test Whether BI 685509 Alone or in Combination With Empagliflozin Helps People With Liver Cirrhosis Caused by Viral Hepatitis or Non-alcoholic Steatohepatitis (NASH) Who Have High Blood Pressure in the Portal Vein (Main Vessel Going to the Liver)

Liver Diseases | Hypertension, Portal

Spain, Denmark, Singapore, Germany, Italy, Austria, Canada, Netherlands, China, Israel, Belgium, United States, Japan, Argentina, France, Romania
Dr. Falk Pharma GmbH

Completed

Different Doses of ZED1227 vs. Placebo in NAFLD (NormaliZED)

NAFLD | Liver Fibrosis

Germany
Baxter Healthcare Corporation

Completed

Efficacy and Safety of Endoscopic Injection of Fibrin Sealant Versus Endoscopic Ligature for Bleeding Esophageal Varices

Esophageal and/or Gastric Varices

Germany
Universitätsklinikum Hamburg-Eppendorf

Completed

Avoiding Postinduction Hypotension: the Clinical ZERO-HYPOTENSION Proof-of-concept Study

Hypotension | Anesthesia | Hypotension on Induction

Germany
AstraZeneca

Completed

A Study to Evaluate the Safety and Efficacy of Cotadutide Given by Subcutaneous Injection in Adult Participants With Non-cirrhotic Non-alcoholic Steatohepatitis With Fibrosis (PROXYMO-ADV)

Non-cirrhotic Non-alcoholic Steatohepatitis With Fibrosis

United States, Austria, Italy, Thailand, Germany, Korea, Republic of, Japan, Malaysia, New Zealand, Spain, Taiwan, Turkey, Australia, Israel, Argentina, Canada, Greece, South Africa, United Kingdom, France
NGM Biopharmaceuticals, Inc

Completed

Study of Aldafermin (NGM282) in Subjects With Compensated Cirrhosis (ALPINE 4)

Nonalcoholic Steatohepatitis | Compensated Cirrhosis

United States, Australia, Belgium, France, Germany, Hong Kong, Poland, Puerto Rico, United Kingdom
Intercept Pharmaceuticals

Completed

Study Evaluating the Efficacy and Safety of Obeticholic Acid in Subjects With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (REVERSE)

Nonalcoholic Steatohepatitis | Compensated Cirrhosis

United States, Spain, France, Australia, New Zealand, Puerto Rico, Germany, Canada, United Kingdom, Hungary, Poland, Ukraine
Technische Universität Dresden
Fraunhofer Institute for Ceramic Technologies and Systems IKTS

Completed

Computer-aided Diagnosis of Ocular Diseases Based on Corneal Biomechanics (EyeTwin)

Glaucoma | Corneal Astigmatism | Keratoconus | Open Angle Glaucoma | Corneal Ectasia | Corneal Disease | Normal Tension Glaucoma

Germany
Novartis Pharmaceuticals
Allergan

Completed

Study of Safety, Tolerability, and Efficacy of a Combination Treatment of LJN452 and CVC in Adult Patients With NASH and Liver Fibrosis (TANDEM)

Non-alcoholic Steatohepatitis (NASH)

United States, Belgium, Spain, Canada, Argentina, Israel, Germany, France, Italy, Turkey, Singapore, Russian Federation, United Kingdom, Czechia, Egypt, India, Latvia
Novartis Pharmaceuticals

Terminated

Efficacy, Safety and Tolerability of the Combination of Tropifexor & Licogliflozin and Each Monotherapy, Compared With Placebo in Adult Patients With NASH and Liver Fibrosis. (ELIVATE)

Non Alcoholic Steatohepatitis (NASH)

United States, South Africa, Spain, Germany, Italy, Taiwan, Canada, Korea, Republic of, Singapore, Bulgaria, Estonia, Mexico, Japan, Denmark, United Kingdom, Colombia, Brazil, Belgium, Russian Federation, Puerto Rico, Chile, Argen... and more
Jonel Trebicka

Completed

Predicting Acute-on-Chronic Liver Failure in Cirrhosis (PREDICT) Study (PREDICT)

Liver Cirrhosis With Acute Decompensation

Spain, Germany, Denmark, Austria, Belgium, United Kingdom, Netherlands, Switzerland, Hungary, Italy, France, Portugal, Slovakia, Turkey
Galmed Research and Development, Ltd.
Medical University of Graz; Tel-Aviv Sourasky Medical Center; Fondazione IRCCS... and other collaborators

Completed

A Clinical Trial to Evaluate the Efficacy and Safety of Two Aramchol Doses Versus Placebo in Patients With NASH (Aramchol_005)

Liver Diseases | Fatty Liver | Non-Alcoholic Steatohepatitis | Liver Fibroses

United States, Chile, Israel, Italy, France, Germany, Mexico, Georgia, Lithuania, Hong Kong, Romania
Celgene

Terminated

Study to Evaluate the Efficacy and Safety of CC-90001 in Participants With Non-alcoholic Steatohepatitis (NASH) and Liver Fibrosis

Liver Cirrhosis | Non-alcoholic Fatty Liver Disease

United States, Spain, Australia, Korea, Republic of, Canada, Germany, France, Japan, United Kingdom, Poland
Bayer

Not yet recruiting

A Study to Learn About the Safety of BAY3283142 in People With Mild to Moderate High Blood Pressure

Chronic Kidney Disease | Arterial Hypertension | Non-proliferative Diabetic Retinopathy

Germany
Gilead Sciences

Terminated

Safety and Efficacy of Simtuzumab (SIM, GS-6624) in Adults With Advanced Liver Fibrosis But Not Cirrhosis Secondary to Non-Alcoholic Steatohepatitis (NASH)

Liver Fibrosis Due to NASH

United States, Spain, France, Canada, Germany, Italy, Puerto Rico, United Kingdom, Belgium
University of Oxford
Assistance Publique - Hôpitaux de Paris; University of Nottingham; Novartis; Pf... and other collaborators

Active, not recruiting

LITMUS Imaging Study

NAFLD | Fibrosis, Liver | NASH - Nonalcoholic Steatohepatitis | NASH | Steatosis of Liver

United Kingdom, Finland, Sweden, Spain, Greece, United States, Switzerland, Italy, France, Germany
Tarsier Pharma

Completed

A Study of TRS01 in Subjects With Active Non-infectious Anterior Uveitis Including Subjects With Uveitic Glaucoma

Uveitic Glaucoma | Non-infectious Anterior Uveitis

United States, Germany, France
Newcastle University
Assistance Publique - Hôpitaux de Paris; Medical University of Vienna; University... and other collaborators

Recruiting

The European NAFLD Registry

Cardiovascular Diseases | Hypertension | Obesity | Hepatocellular Carcinoma | Type 2 Diabetes | NAFLD | Fibrosis, Liver | NASH - Nonalcoholic Steatohepatitis | Dyslipidaemia | NASH | Steatosis of Liver | Other Associated Comorbidities

Netherlands, Germany, United Kingdom, Finland, Belgium, Greece, Italy, Sweden, Portugal, Spain, France, Switzerland
Tobira Therapeutics, Inc.

Terminated

Rollover Study of Cenicriviroc for the Treatment of Liver Fibrosis in Participants With Nonalcoholic Steatohepatitis

Liver Cirrhosis | Non-alcoholic Fatty Liver Disease | Nonalcoholic Steatohepatitis

United States, Australia, France, Germany, Spain, Poland, United Kingdom, Italy, Puerto Rico, Belgium, Hong Kong
Tobira Therapeutics, Inc.

Completed

Efficacy and Safety Study of Cenicriviroc for the Treatment of Nonalcoholic Steatohepatitis (NASH) in Adult Participants With Liver Fibrosis (CENTAUR)

Nonalcoholic Steatohepatitis

Belgium, Spain, Hong Kong, United States, France, Germany, Australia, United Kingdom, Poland, Italy
Bristol-Myers Squibb

Terminated

Safety and Effectiveness of BMS-986263 in Adults With Compensated Cirrhosis (Liver Disease) From Nonalcoholic Steatohepatitis (NASH)

Nonalcoholic Steatohepatitis (NASH)

United States, Germany, Taiwan, United Kingdom, Spain, Argentina, Brazil, France, Israel, Italy, Japan, Korea, Republic of, Belgium, Canada, Puerto Rico, Switzerland
Goethe University

Completed

Gingival Bleeding and Von Willebrand Disease Typ 2 and 3

Von Willebrand Diseases | Gingival Bleeding

Germany
Tobira Therapeutics, Inc.

Terminated

AURORA: A Study for the Efficacy and Safety of Cenicriviroc (CVC) for the Treatment of Liver Fibrosis in Adults With Nonalcoholic Steatohepatitis (NASH) (AURORA)

Nonalcoholic Steatohepatitis

United States, Spain, Australia, Belgium, Israel, Canada, Puerto Rico, Italy, Germany, France, New Zealand, Taiwan, Poland, United Kingdom, Brazil, Austria, Singapore, Portugal, Chile, Greece, Hong Kong, Hungary, Latvia, Mexico, Norway, R... and more
European Foundation for Study of Chronic Liver...

Recruiting

Liver Transplantation in Patients With CirrHosis and Severe Acute-on-Chronic Liver Failure: iNdications and outComEs (CHANCE)

Liver Diseases | Liver Cirrhosis | Acute-On-Chronic Liver Failure | Liver Transplant; Complications

Spain, United States, Germany, Belgium, United Kingdom, Japan, Mexico, Taiwan, Korea, Republic of, Canada, France, Australia, Italy, Argentina, Austria, Brazil, Colombia, Czechia, Hong Kong, India, Netherlands, New Zealand, Poland, Po... and more
AstraZeneca

Completed

Evaluation of Target Organs Damage in Hypertensive Patients (PreVENT-A GP)

Hypertensive | Target Organs Damage | no Known Cardiovascular | no Known Renal Disease

France

Clinical Trials on Non-Cirrhotic Portal Hypertension in Germany

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